Molecular Epidemiology of Carbapenem-Resistant Acinetobacter Baumannii Isolates in Turkiye: Systematic Review

dc.authorid CIFTCI, IHSAN HAKKI/0000-0002-9812-134X
dc.authorid Kahraman Kilbas, Elmas Pinar/0000-0003-1348-625X
dc.authorid KILBAS, IMDAT/0000-0002-8909-4140
dc.authorscopusid 57226442170
dc.authorscopusid 57199149860
dc.authorscopusid 8669926200
dc.authorwosid Ciftci, Ihsan/HTP-7328-2023
dc.authorwosid Kılbaş, Elmas/HRC-3339-2023
dc.contributor.author Kahraman Kılbaş, Elmas Pınar
dc.contributor.author Kilbas, Imdat
dc.contributor.author Ciftci, Ihsan Hakki
dc.contributor.other Tıbbi Hizmetler ve Teknikler Bölümü
dc.date.accessioned 2025-01-11T13:04:14Z
dc.date.available 2025-01-11T13:04:14Z
dc.date.issued 2023
dc.department Fenerbahçe University en_US
dc.department-temp [Kilbas, Elmas Pinar Kahraman] Fenerbahce Univ, Hlth Serv Vocat Sch, Dept Med Lab Tech, Istanbul, Turkiye; [Kilbas, Imdat] Istanbul Univ, Inst Hlth Sci, Med Microbiol Doctorate Program, Istanbul, Turkiye; [Ciftci, Ihsan Hakki] Sakarya Univ, Fac Med, Dept Microbiol, Sakarya, Turkiye en_US
dc.description CIFTCI, IHSAN HAKKI/0000-0002-9812-134X; Kahraman Kilbas, Elmas Pinar/0000-0003-1348-625X; KILBAS, IMDAT/0000-0002-8909-4140 en_US
dc.description.abstract The World Health Organization has designated carbapenem-resistant Acinetobacter baumannii (CRAB) as a "critical" pathogen on the global priority list of antibiotic-resistant bacteria. This study aims to discuss the molecular epidemiology of CRAB isolates in Turkiye in the last 12 years and the prevalence of gene regions associated with resistance or pathogenesis using a systematic review method. Our study consists of a literature search, determination of eligibility and exclusion criteria, qualitative analysis of studies, data extraction, and statistical analysis. All studies were analyzed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Guidelines. The incidence rates of blaOXA-23, blaOXA-23-like, blaOXA-24/40, blaOXA-24/40-like, blaOXA-51, blaOXA-51-like, blaOXA-58, and blaOXA-58-like genes in CRAB strains were 76.4%, 68.6%, 1.2%, 3.4%, 97.0%, 98.6%, 8.4%, and 17.1%, respectively. It was determined that the prevalence of the blaOXA-23 and blaOXA-58 gene regions showed a statistically significant change over the years. Due to the high prevalence of A. baumannii strains carrying the blaOXA-23 variant, it is necessary to follow its geographical distribution and transposon and plasmid movements. Based on available data, molecular surveillance of CRAB strains should be standardized. In addition, sterilization and disinfection processes applied within the scope of an effective struggle against CRAB strains that can remain live on surfaces for a long time should be reviewed frequently. en_US
dc.description.woscitationindex Emerging Sources Citation Index
dc.identifier.citation 3
dc.identifier.doi 10.14744/nci.2022.17003
dc.identifier.endpage 539 en_US
dc.identifier.issn 2148-4902
dc.identifier.issn 2536-4553
dc.identifier.issue 4 en_US
dc.identifier.pmid 37719251
dc.identifier.scopus 2-s2.0-85168956476
dc.identifier.scopusquality Q4
dc.identifier.startpage 531 en_US
dc.identifier.trdizinid 1242655
dc.identifier.uri https://doi.org/10.14744/nci.2022.17003
dc.identifier.uri https://hdl.handle.net/20.500.14627/331
dc.identifier.volume 10 en_US
dc.identifier.wos WOS:001089160600019
dc.language.iso en en_US
dc.publisher Kare Publ en_US
dc.relation.publicationcategory Diğer en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.scopus.citedbyCount 4
dc.subject Acinetobacter Baumannii en_US
dc.subject Blaoxa-23 en_US
dc.subject Blaoxa-24/40 en_US
dc.subject Blaoxa51 en_US
dc.subject Blaoxa58. en_US
dc.title Molecular Epidemiology of Carbapenem-Resistant Acinetobacter Baumannii Isolates in Turkiye: Systematic Review en_US
dc.type Review en_US
dc.wos.citedbyCount 4
dspace.entity.type Publication
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relation.isAuthorOfPublication.latestForDiscovery cc28c727-07ae-40d8-9418-75b409b22d85
relation.isOrgUnitOfPublication 71e25e1a-470b-4aba-b574-5311c2551e2d
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