WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
Browse
Recent Submissions
Article Biopsychosocial-Based Exercise Model for Rheumatic Diseases Via Telerehabilitation: a Case Series With a One Year Follow Up(Nova Southeastern Univ, 2025) Nacar, Nazli Elif; Karaca, Nur Banu; Bulut, Zeynep Irem; Sari, Erkin Oguz; Bulut, SenemPurpose: This study aims to examine the sustainability of the biopsychosocial exercise performed by telerehabilitation on individuals with rheumatic disease, with and without supervision, and investigate the effect of the biopsychosocial-based exercise model on biopsychosocial status, general health status, and anxiety-depression levels of individuals. Method: Twenty patients with rheumatic diseases performed a biopsychosocial-based exercise model Cognitive Exercise Therapy Approach via telerehabilitation with physiotherapist-supervised and unsupervised exercises who continued for three sessions per week for 12 months. Outcome measures were Health Assessment Questionnaire, Hospital Anxiety and Depression Scale, and Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire. Patients were assessed at baseline, 3rd, 6th, 9th, and 12th months. Results: There was no significant difference by time for Health Assessment Questionnaire (p=0.512) and Hospital Anxiety and Depression Scale-anxiety and depression scores (p=0.162 and p=0.825, respectively) between the five measures at the one-year followup. Similarly, there is no significant difference in Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire score outcomes by time (p=0.184). Conclusion: In this study a group of rheumatic patients with face-to-face biopsychosocial exercise habits were able to maintain their exercise habits with realtime telerehabilitation with or without supervised during the 1-year follow-up period during the COVID-19 pandemic was shown. Although there was no improvement in the parameters during the pandemic period when social isolation and depression-anxiety disorders increased, the level of recovery which individuals had previously gained was not adversely affected and the healing properties were preserved with the help of telerehabilitation.Conference Object The Effect of Manual Therapy on Pain, Muscle Activity and Jaw Function in Temporomandibular Joint Dysfunction With Myofascial Origin(Elsevier, 2024) Ates, K.; Coskunsu, D. KaragozogluArticle Cross-Cultural Adaptation, Validity, and Reliability of the Turkish Version of the Cumberland Ankle Instability Tool for Athletes(Human Kinetics Publ Inc, 2025) Yazgan, Elif Aleyna; Coskunsu, Dilber Karagozoglu; Ozdincler, Arzu RazakContext: To cross-cultural translate the Cumberland Ankle Instability Tool (CAIT) to Turkish version (CAIT-T) and to evaluate the validity, reliability, and cutoff score of CAIT-T for Turkish athletic population. Design: The English version of CAIT was translated to CAIT-T based on a guideline of cross-cultural adaptation. Fifty-two athletes with chronic ankle instability and 63 athletes without chronic ankle instability were included in the study. Construct validity was evaluated with correlations between the CAIT-T, Turkish version of Foot Ankle Ability Measure (FAAM-T), and Numeric Rating Scale. CAIT-T was completed twice by each participant at 7 to 10 days intervals to assess test-retest reliability based on the intraclass correlation coefficient, whereas Cronbach alpha evaluated internal consistency. Discriminative validity and content validity of the CAIT-T also evaluated. Results: In construct validity, strong positive correlation was found between CAIT-T and Numeric Rating Scale perceived ankle instability (rho = -.771, P<.001), as well as moderate negative correlations with FAAM-T-activities of daily living and FAAM-T-sports (rho = -.448, P < .001 and rho = -0.541, P < .001, respectively). The CAIT-T demonstrated strong test-retest reliability (intraclass correlation coefficient score of .98) with a good internal consistency (Cronbach alpha: .85). Receiver operating characteristic curve showed a cutoff score of 26.5 (Youden index: 0.78, sensitivity: 0.57, specificity: 0.90.5). No ceiling or floor effects were observed. Conclusions: CAIT-T is a valid and reliable questionnaire for the assessment of chronic ankle instability in the Turkish athletic population.Article Unraveling Hepatic Consequences of Intrauterine Growth Restriction and Catch-Up Growth: Insights From Histological, Biochemical and Metabolomic in Rats(Univ Basque Country Upv-Ehu Press, 2025) Esrefoglu, Mukaddes; Selek, Sahabettin; Koktasoglu, Fatmanur; Bayindir, Nihan; Hekimoglu, Emine-Rumeysa; Kirmizikan, Seda; Bekiroglu, SomerIntrauterine growth restriction (IUGR) is increasingly recognized as a significant risk factor for metabolic disorders in adulthood. Employing a multi-faceted approach encompassing histopathological, immunohistochemical, biochemical, Western-blotting, and metabolomics analyses, this study aimed to elucidate potential metabolite markers of IUGR, and catch-up growth-related metabolic disturbances and the underlying metabolic pathways implicated in IUGR pathogenesis. This study cohort comprised 54 male siblings from 20 Sprague-Dawley female young rats. On the 19th day of gestation, half of the pregnant rats underwent bilateral uterine artery ligation, while the remaining half underwent a simulated surgical intervention involving solely peritoneal incisions. Blood and liver samples were collected from the pups after attaining catch-up growth at the postnatal weeks 2, 4, and 8. IUGR rats exhibited a spectrum of changes including histological abnormalities, altered apoptosis rates, oxidative stress markers, and mitochondrial energy metabolism. Metabolomic analysis revealed dysregulation in multiple metabolic pathways encompassing galactose, propanoate, glycerolipid, cysteine, methionine, and tyrosine metabolism, among others. Notably, disturbances were observed in butanoate, glutathione metabolism, as well as glycolysis/gluconeogenesis. Our metabolomics analysis provides insights into the potential disease susceptibility of individuals born with IUGR, including obesity, diabetes, heart failure, cancer, mental retardation, kidney and liver diseases, and cataracts. These findings underscore the intricate interplay between intrauterine conditions and long-term metabolic health outcomes, highlighting the need for further investigation into preventive and therapeutic strategies aimed at mitigating the risk of metabolic diseases in individuals with a history of IUGR.Article The Effectiveness of Proprioceptive Neuromuscular Facilitation Techniques Versus Conventional Therapy in Patients With Proximal Humerus Fracture: Randomized Controlled Trial(Taylor & Francis Inc, 2025) Kus, Gamze; Alpozgen, Ayse Zengin; Ozdincler, Arzu Razak; Gungor, Feray; Altun, SuleymanBackground To date, no study has investigated the effectiveness of proprioceptive neuromuscular facilitation (PNF) techniques for patients with proximal humerus fractures (PHF). Objective To compare the effect of PNF, conventional physicaltherapy (CPT) on shoulder passive and active range of motion (ROM), function, muscle strength, pain, kinesiophobia, quality of life (QoL), and patient satisfaction in patients with PHF. Methods A total of 40 patients with PHF were randomly allocated into two groups of CPT and PNF. Both groups received treatment programs three times a week for 6 weeks. The primary measures were shoulder ROM, function, and muscle strength. The secondary measures were pain, kinesiophobia, QoL, and patient satisfaction. Results Forty patients analyzed at the end of the study. There were no statistically significant group-by-time interactions for function, pain, shoulder ROM (active and passive), or muscle strength (p > .05). However, there were statistically significant group-by-time interactions in role limitations due to physical health subscale of the 36-item Short Form Survey (SF-36) in CPT (p = .046, eta(2)(p) = 0.078). In addition, a significant difference was found in patient satisfaction at 3 weeks in CPT (p = .021) but no difference at 6 weeks between groups (p > .05). Conclusion The PNF techniques demonstrated similar outcomes to the CPT in reducing pain, improving function and shoulder ROM, and enhancing quality of life in patients with PHF in short time. According to our findings, PNF techniques are as effective as CPT and can be proposed as a potential adjunctive treatment for patients with PHF. Clinicaltrialnumber NCT05960435Article Anti-Lipid Accumulation and Antioxidant Effects of the Root Extract From Rubus Discolor and Its Phytochemical Analysis(Springer, 2025) Sekerler, Turgut; Gulmez, Gizem; Algul, Kader Fatma; Goger, Fatih; Senkardes, Ismail; Sen, Ali; Sener, AzizeRubus species exhibit potent antioxidant properties due to their high phenolic compound content. In our study, phytochemical composition of the extract obtained from roots of Rubus discolor (RDE) was determined using LC-MS/MS. Subsequently, effect of this extract on lipid accumulation was investigated in HepG2 liver cells. For this purpose, HepG2 cells were treated with oleic acid to induce lipid accumulation. The effect of RDE on lipid accumulation was assessed using Oil-Red staining and measuring intracellular triglyceride, cholesterol levels. Melatonin was used as a positive control. Enzymes involved in lipid synthesis, including acetyl-CoA carboxylase (ACC1), fatty acid synthase (FAS), and transcription factor sterol regulatory element-binding protein 1 (SREBP-1c), as well as the antioxidant status, were evaluated by RT-PCR. As dose-dependent, RDE significantly reduced lipid accumulation and each concentrations (25, 50, 100 mu g/mL) of RDE showed 78%, 48%, 38% ratio, respectively for Oil Red O staining. TG was found 1.92 +/- 0.03, 1.76 +/- 0.40, 1.22 +/- 0.13, 1.41 +/- 0.08 mg/mg protein for oleic acid and each concentrations (25, 50, 100 mu g/mL) of RDE, respectively It significantly suppressed ACC1, FAS, and SREBP-1c (p < 0.001, p < 0.001, p < 0.01, respectively) at a dose of 50 g/mL. The extract also exhibited in vitro strong antioxidant and good anti-inflammatory properties. Pedunculagin isomer, ellagic acid and ellagic acid pentoside compounds were found to be the main compounds of RDE with high total phenolic content. The results indicate that RDE has the potential to prevent lipid accumulation. These findings could provide a basis for further studies on the potential therapeutic effect of Rubus discolor in the treatment of NAFLD.Conference Object The Effect of Myrtus Communis Extract on High Fat Diet Induced Liver Damage in Rats(Wiley, 2025) Sucu, Gizem; Kabatas, Gul Sinemcan; Ertas, Busra; Sen, Ali; Sener, Goksel; Ercan, Feriha; Akakin, DilekArticle The Effect of Vitamin D and Paricalcitol on Protein Disulfide Isomerase(Marmara Univ, Fac Pharmacy, 2024) Koksal, Muhammed Murat; Sekerler, Turgut; Sener, AzizeProtein disulfide isomerase (PDI), a multifunctional protein plays an important role as oxidoreductase, isomerase and chaperone in the cell. Prior studies have identified PDI is highly expressed in many different cancer types and presented as a new potential target for cancer treatment. Here, we investigated vitamin D and its analogue paricalcitol in silico interaction of the human PDI and inhibition of PDI reductase activity in vitro. We observed a non-covalent mechanism where the main skeleton of the vitamin D3 and paricalcitol structure is located at the hydrophobic site in the b' domain of PDI and forms a hydrogen bond with a residue (His138) in this domain. They also form multiple weak hydrophobic interactions with various chemical groups of the b' subunit. For the first time, we demonstrate that 1,25dihydroxyvitamin D3 (1 alpha,25(OH)2 vitamin D3) and paricalcitol inhibit the PDI reductase activity in vitro and their IC50 values are 20.79 +/- 1.43 nmol/L and 32.82 +/- 3.15 nmol/L respectively. The two compounds can also block the denitrosation activity of PDI.Article Determining the Injury Risk Levels of Kyorugi and Poomsae Taekwondo Athletes and Comparing Them With Selected Athletic Performance Parameters(Stowarzyszenie Idokan Polska-Idokan Poland Assoc, 2025) Ergin, Ceren z.; Pinar, Yeliz; Sani, Fatih; Cumbur, Cansel; Ramazanoglu, NusretBackground. Different disciplines within the same sport can lead to varying injury risks and performance requirements due to differences in energy systems, techniques, and competition rules. Problem and aim. This study assesses and compares injury risk levels among taekwondo athletes in the kyorugi and poomsae disciplines alongside selected athletic performance parameters. Material and Method. The study included 10 women (22 +/- 2.37 years) and 10 men (22 +/- 1.25 years) from the kyorugi discipline, and 10 women (19.4 +/- 2.55 years) and 10 men (18.8 +/- 3.29 years) from poomsae. All participants had competed in licensed elite-level competitions for at least 4 years. Injury risk and performance were evaluated using the Y balance test (YBT), reactive strength index (RSI), and functional movement screen (FMS). Results. Significant differences were found between male kyorugi and poomsae athletes in rotary stability (p=0.042), dominant leg Y balance (p=0.012), and composite scores (p=0.012). For female athletes, differences in dominant leg Y balance (p=0.049), anterior reach (p=0.027), RSI (p=0.001), and jump height (p=0.001) were noted. Female poomsae athletes had RSI values below normative standards. According to the YBT, the male poomsae group had the lowest number of athletes at risk of injury, whereas the female kyorugi group had the highest. Conclusions. Generally, taekwondo athletes displayed low injury risks based on FMS and YBT values, with moderate to low RSI risk levels. Increased reactive strength may correlate with higher injury risk. Female poomsae athletes should work to improve RSI scores, while kyorugi athletes should focus on strategies to address asymmetry-related injuries.Article Cochleogram-Based Speech Emotion Recognition With the Cascade of Asymmetric Resonators With Fast-Acting Compression Using Time-Distributed Convolutional Long Short-Term Memory and Support Vector Machines(Mdpi, 2025) Parlak, CevahirFeature extraction is a crucial stage in speech emotion recognition applications, and filter banks with their related statistical functions are widely used for this purpose. Although Mel filters and MFCCs achieve outstanding results, they do not perfectly model the structure of the human ear, as they use a simplified mechanism to simulate the functioning of human cochlear structures. The Mel filters system is not a perfect representation of human hearing, but merely an engineering shortcut to suppress the pitch and low-frequency components, which have little use in traditional speech recognition applications. However, speech emotion recognition classification is heavily related to pitch and low-frequency component features. The newly tailored CARFAC 24 model is a sophisticated system for analyzing human speech and is designed to best simulate the functionalities of the human cochlea. In this study, we use the CARFAC 24 system for speech emotion recognition and compare it with state-of-the-art systems using speaker-independent studies conducted with Time-Distributed Convolutional LSTM networks and Support Vector Machines, with the use of the ASED and the NEMO emotional speech dataset. The results demonstrate that CARFAC 24 is a valuable alternative to Mel and MFCC features in speech emotion recognition applications.Article The Effects of Pelvic Floor Muscle Training Applied Via Telerehabilitation During the Postpartum Period: a Randomized Controlled Study(Mary Ann Liebert, inc, 2025) Razak Ozdincler, Arzu; Korkmaz Dayican, Damla; Ozyurek, BurcinPurpose: To examine the short- and medium-term effects of pelvic floor muscle training (PFMT) applied via telerehabilitation (TR) on pelvic floor muscle function, pelvic floor symptoms, and quality of life. Methods: Fifty-eight women between the ages of 18 and 35 who were between 6 and 8 weeks postpartum were included. The participants were randomized into the PFMT applied via TR (TR-PFMT) group or the supervised PFMT (S-PFMT) group. The PFMT was performed for 8 weeks, 2 days a week, and 45-50 min a day. The participants' pelvic floor muscle function, pelvic floor symptoms, and quality of life were evaluated with the superficial electromyography, the Pelvic Floor Distress Inventory-20 (PFDI-20), and the Pelvic Floor Impact Questionnaire-7, respectively. Results: Phasic, tonic, and endurance activities of the pelvic floor muscles were significantly higher in both groups immediately after and 8 weeks after the exercise program (all p < 0.05). In addition, total PFDI-20 and all subscales' scores decreased significantly in the TR-PFMT group (all p < 0.05). In the S-PFMT group, total PFDI-20 (p = 0.012) and Urinary Distress Inventory-6 (p = 0.012) scores improved significantly. A significant difference was found between the groups in favor of the TR-PFMT group in terms of total PFDI-20 (p = 0.024; p = 0.024) and Urinary Distress Inventory-6 (p = 0.033; p = 0.040) scores immediately after and 8 weeks after the exercise program. Conclusions: TR-PFMT and S-PFMT improved women's pelvic floor muscle function, pelvic floor symptoms, and quality of life in the short and medium term. Improvement in urinary symptoms was greater after TR-PFMT. TR-PFMT should be considered for postpartum women.Article Relationship Between E-Health Literacy and Healthy Lifestyle Behaviours of Turkish Health Sciences Students(Emerald Publishing, 2025) Çakır, Furkan; Ozturk, Sergen; Gerçek, Hasan; Eryildiz, Ezgi; Kartal, Gokce; Polat, Mine GuldenPurpose: E-health literacy (EHL) and healthy lifestyle behaviours (HLBs) are important for individuals receiving health education. Health professionals of the future should be conscious, e-health literate and develop HLBs. The aims of this study were to determine the EHL and HLBs of university students receiving health education and to examine the relationship between them. Design/methodology/approach: A total of 1,454 health sciences students, between the ages of 18–27, were included in the study. Participants' data were collected online via Google Forms. Participants' EHL levels were assessed with the E-Health Literacy Scale. Participants' HLB were assessed with the Healthy Lifestyle Behaviours Scale II. Findings: Positive weak correlation was found between EHL and HLB (p < 0.001, r = 0.329). EHL scores of bachelor’s degree students were higher than associate degree students (p = 0.004). HBL total score bachelor’s and associate degree student scores were similar (p = 0.714). Originality/value: This article addresses an important gap in understanding health sciences students' online reading habits about health and their relationship to HLB. Considering that there is a positive relationship between EHL and HLBs of students in the health departments of universities, increasing the EHL levels of students will help to increase HLBs. © 2025, Emerald Publishing Limited.Article Relationship of Handwriting Skills With Cognitive Functions and Sensory Processing in the Older Adults(Routledge Journals, Taylor & Francis Ltd, 2025) Sirma, Gamze Cagla; Yucel, HulyaAims: Handwriting involves complex processes, including cognitive function and sensory processing. Cognitive function and sensory processing change with aging. However, the relationship between these parameters remains unclear. The aim of this study is to investigate the relationship between cognitive function and sensory processing with handwriting skills in the older adults. Methods: Fifty-six community-dwelling individuals aged 65-75 years completed a sociodemographic questionnaire, the Adolescent/Adult Sensory Profile, the Montreal Cognitive Assessment (MoCA), and handwriting tasks. Results: The mean age was 70.62 +/- 3.49 years. The strongest correlations were observed between MoCA and the handwriting subtest. Low registration, sensory sensitivity, and sensation avoiding were positively correlated with handwriting subtests. Moreover, the results showed that these skills were also predictive of older adults' handwriting skills (p < 0.05). Conclusions: It is crucial for occupational therapists and physiotherapists to integrate handwriting skill assessment into their clinical settings in terms of its relationship with cognitive and sensory processing.Article Evaluating the Potential Role of Ai Chatbots in Designing Personalized Exercise Programs for Weight Management(Taylor & Francis inc, 2025) Sarac, Hakan; Ulusoy, Ismet Tarik; Alpay, Janset; Odemis, Hasan; Sogut, MustafaThis study aimed to evaluate the effectiveness and potential use of artificial intelligence (AI) chatbots in developing personalized exercise programs for weight management. Exercise programs were developed by ChatGPT-4, ChatGPT-4o, Gemini-1.5 Pro models, and a group of human expert trainers for a hypothetical obese individual case. All exercise programs were assessed based on the American College of Sports Medicine (ACSM) and National Academy of Sports Medicine (NASM) guidelines. The chatbot-generated programs were consistent with ACSM and NASM standards, indicating their potential use in low-resource settings. Nevertheless, considerable differences were found between human trainers and chatbots in key parameters, including initial load and target heart rate zone recommendations. While AI chatbots have the potential to enhance accessibility, human expertise remains essential to ensure program safety and effectiveness. The results of this study provide insights into the potential role of AI chatbots in personalized exercise programs for weight management.Article Relationship Between Executive Functions and School Readiness in Kindergarten Children With Cochlear Implant(Routledge Journals, Taylor & Francis Ltd, 2025) Bektas, Selen Aydoner; Bumin, GoncaThis study aimed to examine the relationship between executive functions and school readiness of kindergarten children with cochlear implants. The study included 109 children between the ages of 57 and 71 months, who were enrolled in a special education practice school for the deaf and followed up by the ear, nose, and throat diseases clinic, who had bilateral severe or profound sensorineural type hearing loss and who used bilateral cochlear implants. The participants' teachers filled out the Childhood Executive Functions Inventory and the Primary School Readiness Scale. The findings showed a significant relationship between the Childhood Executive Functions Inventory-Working Memory, Inhibitory Control, and Total scores and Primary School Readiness Scale of kindergarten children with cochlear implant (r values are -.793, -.819., and -.768, respectively; p < 0.01). The results obtained from this study emphasize the importance of interventions that support the executive functions and school readiness of children with cochlear implants from the earliest period and increase their participation in school life.Article Post-Covid Neutropenia in an Infant With Thalassemia Minor: Case Report(Wiley, 2025) Elsherif, Yasmine; Elsherif, Omar; Karimi, Mehran; Ibrahim, Ismail A.; Abukhadijah, Hana J.This case of an 11-month-old female who developed severe neutropenia following COVID-19 infection underscores the need for heightened vigilance and monitoring of hematological parameters in infants post-COVID-19. The exact mechanism of COVID-19-induced neutropenia is not fully understood, but it may involve cytokine-induced suppression of hematopoiesis and bone marrow repression due to the inflammatory response. Given the potential for serious clinical implications, including increased susceptibility to infections, it is crucial to effectively identify and manage neutropenia in this vulnerable population. Further research is necessary to elucidate the underlying mechanisms and optimize treatment strategies for COVID-19-related hematological complications in infants.Article The Impact of Game-Based Learning (Gbl) on Efl Learners' Buoyancy, Directed Motivational Currents (Dmcs), and Language Learning(Gate Assoc Teaching & Education-Gate, Switzerland, 2025) Arzhangi, Mohadeseh; Ghanizadeh, AfsanehThe teaching approach of game-based learning emphasizes the creation, improvement, and use of games for educational purposes and training to achieve specific learning goals. A quasi-experimental research study using quantitative methods was conducted to investigate the impact of Game-Based Learning on the academic resilience, Directed Motivational Currents, and language learning of English as Foreign Language (EFL) Learners. The study involved 30 pre- intermediate students from two classes at the Iran-Europe Language Institute in Tehran, with one class assigned to the experimental group and the other to the control group. To provide a baseline for comparison, the experimental group participated in game-based learning, while the control group received traditional education devoid of any game-based activities. In effect, the experimental group engaged in digital and non-digital games related to vocabulary, grammar, and other language components alongside with some real-time quizzes, whereas the control group adhered to traditional teaching procedure in instruction, revision, and mainstream quizzes, in a non-gamified context. Data were collected using the L2 Buoyancy Questionnaire and the Persian version of the Dynamic online DMC Disposition Questionnaire. Results indicated statistically significant improvements in the experimental group`s academic buoyancy, DMC, and language proficiency with effect sizes of 1.96, 0.71.272, and 0.585 respectively, compared to the control group. Derived from these findings, teachers are recommended to integrate game- based learning by incorporating interactive language tasks such as digital simulation or vocabulary games into their lesson plans, helping the students engage more with the material effectively. Furthermore, educational institutions and administrators can elevate students' knowledge quality by incorporating game- based instruction into curricula, by providing structured gamified tasks aligned with curriculum objectives to make learning more effective and engaging.Article Can Manual Therapy Alter Muscle Stiffness in Patients With Spinal Accessory Nerve Injury(Wiley, 2025) Simsek, Ferhat; Naci, Baha; Kilicoglu, Meltem Bozaci; Alkan, Zeynep; Topcuoglu, Osman Melih; Gormez, Aysegul; Okyar, Ali FethiObjective. Shoulder and neck dysfunctions resulting from spinal accessory nerve injury impair quality of life. This study aims to investigate the effects of manual therapy in combination with standard physiotherapy on the mechanical properties of muscle, neck and shoulder function, pain, and quality of life in head and neck cancer patients. Study Design. Prospective, randomized, controlled, double-blind clinical trial. Setting. Department of Otorhinolaryngology Head and Neck Surgery of a university hospital. Methods. A total of 26 participants were randomized into two groups. The control group (n = 11) received standard physiotherapy including therapeutic exercises, scar tissue massage, and education. The intervention group (n = 10) received manual therapy consisting of soft tissue, myofascial release, and mobilization techniques in combination with standard physiotherapy. Outcome measures were mechanical properties of muscle, neck and shoulder active range of motion, shoulder pain and disability, and quality of life. Results. Upper trapezius and sternocleidomastoid muscle stiffness increased significantly in the control group (P < .01), whereas a significant reduction was observed in the intervention group compared to the control group (P = .001). A reduction in muscle thickness was observed bilaterally in both groups (P < .01). Moreover, all participants showed improvements in neck and shoulder active range of motion, shoulder pain, and quality of life (P < .01). Conclusion. Manual therapy in addition to standard physiotherapy was more effective in improving neck and shoulder function, quality of life, and reducing muscle stiffness compared to standard physiotherapy alone. Therefore, clinicians should consider incorporating manual therapy into their treatment protocols to optimize patient outcomes.Article Citation - Scopus: 0Coach Candidates' and Coaches' Nutrition Knowledge Affects Dietary Recommendations Indirectly: Mediator Effects of Self-Efficacy(Mdpi, 2025) Altinok, Oyku; Bas, MuratBackground/Objectives: The nutritional knowledge and behavior of athletes are considerably influenced by the dietary recommendations of their coaches, which, in turn, affect their health and performance. In the context of social cognitive theory, this study examines the impact of general and sports nutrition knowledge (GeSNK), nutrition self-efficacy (NSE), and nutrition counseling self-efficacy (NCSE) on the dietary recommendations (DRs) provided by coach candidates and coaches (CC&Cs). Additionally, it explores variations in GeSNK, NSE, and NCSE among CC&Cs based on their sports positions, genders, and types of sports. Methods: This study included 70 coach candidates and 102 coaches, with data collected via validated scales for GeSNK, NSE, and NCSE. Using the PROCESS macro, the serial multiple mediator model was applied, and group comparisons were conducted via the Mann-Whitney U test. Results: The results revealed that 36% of participants achieved adequate GeSNK scores, but only 6.4% abstained from providing DRs. Participants engaged in individual sports exhibited higher NSE and NCSE scores than those involved in team sports. Additionally, 22.7% of CC&Cs identified their former coaches as a primary source of nutrition information. The study findings revealed that GeSNK, NSE, and NCSE significantly influenced DRs, collectively accounting for 23% of the variance in DRs. The direct effect of NCSE on DRs was statistically significant, whereas the direct effects of GeSNK and NSE were not significant. GeSNK and NSE jointly explained only 41% of the variance in NCSE, suggesting that additional factors influencing NCSE and DRs remain unexplored. Conclusions: To address the issue of inadequate dietary recommendations stemming from insufficient information, it is crucial to identify and understand these additional factors affecting NCSE and DRs. Diversifying nutrition education programs to enhance the nutrition knowledge of CC&Cs is essential. Furthermore, fostering collaboration between CC&Cs and nutritionists can ensure that athletes receive accurate and comprehensive nutritional guidance.Article Citation - Scopus: 0Validity, Reliability and Responsiveness of the Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (bety-Bq) in Knee Osteoarthritis(Springer Heidelberg, 2025) Bulut, Zeynep Irem; Unal, Edibe; Oksuz, Sevim; Dogru, Atalay; Akyol, Ahmet; Yakut, YavuzPurposeThis study was planned to test whether the Cognitive Exercise Therapy Approach- Biopsychosocial Questionnaire (BETY-BQ) is an appropriate questionnaire in assessing the biopsychosocial status in KOA.MethodsFrequently used assessment tools, OA-specific scale The Western Ontario and McMaster Universities OA Index, the Hospital Anxiety and Depression Scale, and the Short Form-36 were utilized for the validity and responsiveness of BETY-BQ in individuals with KOA. The test-retest method, internal consistency analysis, and item analysis were used to test reliability. For the test-retest method, BETY-BQ was administered again to the same 30 individuals 1 week later. To assess the responsiveness of the BETY-BQ, individuals who underwent medical treatment were subjected to a second round of questionnaire administration after a 3-month interval.ResultsModerate to weak correlations between BETY-BQ and the other questionnaires ensued the divergent validity. According to the confirmatory factor analysis, all goodness-of-fit indices of BETY-BQ were acceptable (CMIN/df = 2.212; RMSEA = 0.080; SRMR = 0.08). Both Cronbach's alpha (0.900) and ICC value (0.941) showed that the BETY-BQ has excellent reliability in the KOA population. The Bland-Altman Plot showed high agreement as all differences between the first and second BETY-BQ were found between the 95% lower and upper limits. BETY-BQ demonstrated moderate responsiveness as the effect size and standardized mean response were 0.656 and 0.566, respectively.ConclusionA valid, reliable, responsive, multi-dimensional, and self-reported questionnaire for measuring biopsychosocial status in KOA was introduced to the use of healthcare professionals.