FBU GCRIS Standard Database
The scientific memory of Fenerbahçe University. Publications, projects, and researchers—all in one place. The heart of open science beats here. 'Open Science. Visible Impact.'
Recent Submitted Publications
Updating the Signal-To Level To Reduce Anti-Hepatitis C Virus False Positivity
(Kowsar Medical Institute, 2021) Oztürk, S.; Ağalar, C.
Background: Anti-hepatitis C virus (anti-HCV) is the only screening test being used in the diagnosis of hepatitis C. In this study, we examined anti-HCV positivity rates in our hospital. Objectives: The aim of administering the anti-HCV test was to distinguish patients with hepatitis C infection from false positivity in patients with reactive results. Methods: The anti-HCV tests were performed at Fatih Sultan Mehmet Training and Research Hospital in Istanbul, Turkey, between January 1, 2015 and December 31, 2019. The patients were evaluated retrospectively in terms of age, gender, anti-HCV titer, the clinic for which the examination was requested, the reason for the examination, and the history of hepatitis C. Results: In this study, 511 patients who had two negative polymerase chain reaction (PCR) results were evaluated as false positive cases and enrolled. The cut-off value was found to be 7.5 IU/ml, with the highest sensitivity of 94.4% and specificity of 94.5% (area under the curve [AUC]: 0.982). The lowest anti-HCV titer (5.2) was from patients without acute hepatitis, who were HCV-RNA positive and diagnosed with chronic hepatitis C. Conclusions: It may be more appropriate to report anti-HCV cut-off value of 0-5 as negative, 5-7.5 as borderline, and > 7.5 as positive. Working with a more acceptable cut-off level with a greater number of tests can help identify patients with asymptomatic HCV infection. Also, it can possibly reduce the cost due to a decrease in the number of PCR tests administered. © 2021, Author(s).
Citation - WoS: 22
Citation - Scopus: 31
Digital Transformation in Project-Based Manufacturing: Developing the Isa-95 Model for Vertical Integration
(Elsevier, 2022) Apiliogullari, Lutfi
The Smart Factory is the intelligent management of all business operations that aims to produce innovative products in the most efficient and faster way through the cyber-physical system (CPS). CPS integrates the cyber (IT) and the physical world (OT) through the hierarchical layers of ISA-95 model and forms the backbone of Industry 4.0. The CPS plays a crucial role in transforming data from interconnected systems, and it is a pre-requisite for the entire system to be able to interact. The ISA-95 model consists of components that can be used to determine how the interaction between domains vertically within the facility. However, the current ISA-95 Model does not include all the components that need to be integrated in vertical integration of all domains. The product domain is one of them. All IT and OT components need to be represented in the ISA-95 layers to achieve an ideal CPS structure. In this study, all components needed to achieve the ideal CPS structure have been identified in an expanded ISA-95 Model for project-based manufacturers. An extended ISA-95 model is proposed so that each manufacturing industry can use it in the digital transformation process by adding a product domain and connectivity layer to the Model. The Model was tested and confirmed, by conducting a case study which was based on implementing the vertical integration on it. This model helps businesses to develop more effective digital transformation strategies by defining where they should focus on or from where they should start the digital transformation processes.
Determining the Type 2 Diabetes Risks and Healthy Lifestyle Behaviors of First Year University Students (Vol 6, Pg 420, 2022)
(Dokuz Eylul Univ inst Health Sciences, 2023) Eroglu, Nermin; Temiz, Gamze
Bölgeselcilik Kavramı Işığında Karadeniz Bölgesi: Soğuk Savaş Sonrası Dış Politika Dinamikleri
(2019) Sıvış, Efe
Genişletilmiş Karadeniz Bölgesi Avrupa, Orta Asya ve Orta Doğu yollarının kesiştiği önemli bir noktadır. ÜçNATO üyesi devlet ve partner ülkesine ev sahipliği yapan Karadeniz; Rusya, ABD, Türkiye ve AB içinbölgesel egemenlik için bir mücadele alanı olarak tebarüz etmiştir. 2014’te Kırım’ın ilhakıyla beraberbölgenin daha çok dikkat çekmesi Rusya’nın Karadeniz’deki askeri mevcudiyetini artırmasına yol açmış vebu durum NATO üyeleri nezdinde doğrudan bir tehdit algılamasına neden olmuştur. Bu çalışma özelliklebölgesel işbirliğinin güvenlik yönüne odaklanarak, bölgeselcilik çerçevesinde bölgenin karmaşık yapısınıhem AB hem de ABD’nin bakış açısından incelemeyi hedeflemektedir. Çalışmada ABD’nin GenişletilmişKaradeniz Bölgesi, AB’nin Karadeniz Stratejisi ve NATO’nun bölgeye yönelik politikaları bölgeselcilikkavramı çerçevesinde ele alınmaktadır.
Citation - WoS: 2
Citation - Scopus: 3
Effect of Pacifier and Pacifier With Dextrose in Reducing Pain During Orogastric Tube Insertion in Newborns: a Randomized Controlled Trial
(Springernature, 2024) Akkaya-Gul, Aysenur; Ozyazicioglu, Nurcan
OBJECTIVE: This study aimed to assess the efficacy of pacifier use, with and without 25% dextrose, in reducing pain during orogastric tube insertion in newborns. STUDY DESIGN: In a randomized controlled trial involving 60 newborns at a public hospital from April to December 2019,participants were divided into three groups: pacifier (n=20), pacifier with 25% dextrose (n=20), and control (n=20). A pacifier, with and without dextrose, was used for the experimental groups, while the control group performed a routine procedure. Neonatal infant pain scale, crying duration, heart rate (HR), and oxygen saturation (SpO2) were evaluated. RESULTS: Results indicated that the control group experienced significantly higher pain levels, elevated HRs, decreased SpO2, and prolonged crying. Conversely, the pacifier with 25% dextrose group showed a notable reduction in crying duration. CONCLUSION: A pacifier, with and without 25% dextrose, effectively reduces pain and improves physiological and behavioral parameters during orogastric tube insertion.