Effects of Combined Triflow, Deep Breathing and Coughing Exercises on Postoperative Pulmonary Function After Mitral Valve Replacement: A Randomized Controlled Trial

dc.contributor.author Akinci, Naile
dc.contributor.author Eren, Esra
dc.date.accessioned 2026-03-12T14:36:05Z
dc.date.available 2026-03-12T14:36:05Z
dc.date.issued 2026
dc.description.abstract Background Postoperative pulmonary complications remain a major cause of morbidity after cardiac valve surgery. Although incentive spirometry (Triflow) is routinely used in postoperative care, evidence regarding the additional benefits of combining Triflow with deep breathing and coughing exercises remains limited. This study aimed to evaluate the effects of combined Triflow, deep breathing, and coughing exercises on postoperative pulmonary function in adult patients undergoing mitral valve replacement. Methods This randomized controlled, single-blind trial was conducted between May and August 2025 in a private hospital in Istanbul. A total of 60 adult patients undergoing mitral valve replacement were randomly allocated to an experimental group (n = 30) or a control group (n = 30) using simple randomization. The experimental group performed Triflow combined with deep breathing and coughing exercises, while the control group performed Triflow alone. Results Postoperative SpO(2) levels were significantly higher in the experimental group at T1 (p = 0.009; 95% CI: 0.46-3.14), T2 (p < 0.001; 95% CI: 1.57-3.43), and T3 (p < 0.001; 95% CI: 2.72-4.54). The FEV1/FVC ratio increased significantly in the experimental group compared with the control group at discharge (p < 0.001; 95% CI: 4.46-6.41). Respiratory rate was significantly higher in the experimental group at T1 (p < 0.001; 95% CI: 1.68-4.45), T2 (p < 0.001; 95% CI: 3.34-6.26), and T3 (p < 0.001; 95% CI: 5.23-8.37). Hematocrit levels were significantly lower in the experimental group at T1 (p = 0.039; 95% CI: -8.32 to - 0.24), T2 (p = 0.007; 95% CI: -8.29 to - 1.40), and T3 (p = 0.034; 95% CI: -6.54 to - 0.28). Pain scores were significantly lower in the experimental group at T1 (p < 0.001; 95% CI: -2.82 to - 1.71) and T2 (p < 0.001; 95% CI: -1.98 to - 1.08). Time to first mobilization was significantly shorter in the experimental group (p < 0.001; 95% CI: -2.94 to - 1.26). No postoperative pulmonary complications were observed in either group. Conclusion The combined application of Triflow, deep breathing, and coughing exercises was associated with significant improvements in postoperative pulmonary function, oxygen saturation, pain reduction, and earlier mobilization compared with Triflow alone in patients undergoing mitral valve replacement. These findings suggest that a structured, combined respiratory exercise protocol may provide additional clinical benefits in the early postoperative period. en_US
dc.identifier.doi 10.1186/s12893-026-03542-7
dc.identifier.issn 1471-2482
dc.identifier.scopus 2-s2.0-105031368522
dc.identifier.uri https://doi.org/10.1186/s12893-026-03542-7
dc.identifier.uri https://hdl.handle.net/20.500.14627/1453
dc.language.iso en en_US
dc.publisher BMC en_US
dc.relation.ispartof BMC Surgery en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Mitral Valve Replacement en_US
dc.subject Breathing Exercises en_US
dc.subject Pulmonary Function en_US
dc.subject Postoperative Complications en_US
dc.title Effects of Combined Triflow, Deep Breathing and Coughing Exercises on Postoperative Pulmonary Function After Mitral Valve Replacement: A Randomized Controlled Trial en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.scopusid 58190300900
gdc.author.scopusid 58902988200
gdc.description.department Fenerbahçe University en_US
gdc.description.departmenttemp [Akinci, Naile] Fenerbahce Univ, Fac Hlth Sci, Dept Nursing, Istanbul, Turkiye; [Eren, Esra] Istanbul Medipol Univ, Fac Hlth Sci, Dept Nursing, Istanbul, Turkiye en_US
gdc.description.issue 1 en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q2
gdc.description.volume 26 en_US
gdc.description.woscitationindex Science Citation Index Expanded
gdc.description.wosquality Q2
gdc.identifier.pmid 41668083
gdc.identifier.wos WOS:001702630200001
gdc.index.type WoS
gdc.index.type Scopus
gdc.index.type PubMed

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