The Effects Of<i> Panax</I><i> Ginseng</I> on Serum Oxidative Stress Following Bisphenol a Exposure

dc.authorscopusid 59307380000
dc.authorscopusid 58674094100
dc.authorscopusid 58563673800
dc.authorscopusid 55662834600
dc.authorscopusid 24067816000
dc.contributor.author Ede Pazarbaşı, Seren
dc.contributor.author Şener, Göksel
dc.contributor.author Dorucu, Dogancan
dc.contributor.author Sener, Goksel
dc.contributor.author Tunali-Akbay, Tugba
dc.contributor.other Eczane Hizmetleri Bölümü
dc.contributor.other Eczacılık Meslek Bilimleri Bölümü
dc.date.accessioned 2025-01-11T13:03:13Z
dc.date.available 2025-01-11T13:03:13Z
dc.date.issued 2024
dc.department Fenerbahçe University en_US
dc.department-temp [Fazalyar, Najiullah; Pazarbasi, Seren Ede] Marmara Univ, Inst Hlth Sci, Dept Biochem, Istanbul, Turkiye; [Pazarbasi, Seren Ede] Fenerbahce Univ, Vocat Sch Hlth Serv, Istanbul, Turkiye; [Dorucu, Dogancan] Marmara Univ, Fac Med, Dept Urol, Istanbul, Turkiye; [Sener, Goksel] Fenerbahce Univ, Fac Pharm, Dept Pharmacol, Istanbul, Turkiye; [Tunali-Akbay, Tugba] Marmara Univ, Fac Dent, Dept Basic Med Sci, Istanbul, Turkiye en_US
dc.description.abstract Objective: Bisphenol A (BPA) is a toxic compound that causes oxidative stress by disrupting antioxidant enzymes and promoting tissue lipid peroxidation. This study aimed to examine the impacts of BPA on serum oxidative stress in rats and to detect the antioxidant feature of Panax ginseng (PxG) in reducing BPA-induced oxidative stress. Materials and Methods: Wistar Albino rats (250-300 g) were divided into control, control + PxG, BPA, and BPA + PxG groups. 50 mg/kg BPA and 100 mg/g PxG were given for six weeks. Serum total antioxidant and oxidant status, lipid peroxidation, and glutathione levels were determined. Results: BPA administration increased total oxidant status and lipid peroxidation, while PxG administration to the BPA group decreased these parameters. PxG also increased total antioxidant status and glutathione levels compared to the BPA group. Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure. en_US
dc.description.sponsorship Marmara University Scientific Research Projects Unit [TYL-2024-11206] en_US
dc.description.sponsorship Financial Disclosure: This study was funded by a grant from the Marmara University Scientific Research Projects Unit (TYL-2024-11206) en_US
dc.description.woscitationindex Emerging Sources Citation Index
dc.identifier.citation 0
dc.identifier.doi 10.26650/experimed.1443398
dc.identifier.endpage 72 en_US
dc.identifier.issn 2667-5846
dc.identifier.issue 2 en_US
dc.identifier.scopus 2-s2.0-85202700666
dc.identifier.scopusquality Q4
dc.identifier.startpage 68 en_US
dc.identifier.trdizinid 1277159
dc.identifier.uri https://doi.org/10.26650/experimed.1443398
dc.identifier.uri https://hdl.handle.net/20.500.14627/239
dc.identifier.volume 14 en_US
dc.identifier.wos WOS:001322096300002
dc.identifier.wosquality N/A
dc.language.iso en en_US
dc.publisher Istanbul Univ en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.scopus.citedbyCount 0
dc.subject Bisphenol A en_US
dc.subject Panax Ginseng en_US
dc.subject Oxidative Stress en_US
dc.subject Antioxidant Effect en_US
dc.title The Effects Of<i> Panax</I><i> Ginseng</I> on Serum Oxidative Stress Following Bisphenol a Exposure en_US
dc.type Article en_US
dc.wos.citedbyCount 0
dspace.entity.type Publication
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