PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/8
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Article Ludwig's Angina in a 6-Year Child: Case Report(Wiley, 2025) Akbari, Negarin; Razavi, Ali; Sabzi, Zahra; Parhiz, JabbarLudwig's angina is a rare but potentially fatal cellulitis that affects the submandibular, sublingual, and submental spaces, typically triggered by dental infections. This case report details a severe presentation of Ludwig's angina in a 6-year-old girl who presented with submandibular swelling, fever, voice alterations, and respiratory distress. Diagnosis was based on clinical evaluation, supported by CT imaging, revealing significant airway narrowing and lymphadenopathy. The patient was promptly intubated to secure the airway, followed by emergency surgical drainage and intravenous antibiotics. Postoperative care included sedation, ongoing monitoring in the PICU, and close follow-up by multiple specialties. After a 10-day hospitalization, the patient showed significant recovery with no complications. The case underscores the importance of early diagnosis and intervention in preventing severe complications such as airway obstruction, sepsis, and mediastinal spread. It highlights the critical role of interdisciplinary collaboration, including pediatric infectious disease specialists, surgeons, and anesthesiologists, in managing this life-threatening condition effectively.Article Post-Covid Neutropenia in an Infant With Thalassemia Minor: Case Report(Wiley, 2025) Elsherif, Yasmine; Elsherif, Omar; Karimi, Mehran; Ibrahim, Ismail A.; Abukhadijah, Hana J.This case of an 11-month-old female who developed severe neutropenia following COVID-19 infection underscores the need for heightened vigilance and monitoring of hematological parameters in infants post-COVID-19. The exact mechanism of COVID-19-induced neutropenia is not fully understood, but it may involve cytokine-induced suppression of hematopoiesis and bone marrow repression due to the inflammatory response. Given the potential for serious clinical implications, including increased susceptibility to infections, it is crucial to effectively identify and manage neutropenia in this vulnerable population. Further research is necessary to elucidate the underlying mechanisms and optimize treatment strategies for COVID-19-related hematological complications in infants.Article Tinea Capitis (favus) in a 8-Year Child: Case Report(Wiley, 2024) Akbari, Negarin; Parhiz, Jabbar; Sabzi, ZahraKey Clinical MessageIn examining any scalp itch or skin lesions, especially in children with long hair, fungal lesions under the hair may not be diagnosed in a timely manner. Additionally, fungal infection of the scalp, known as tinea capitis, is considered a chronic condition and if left untreated, it can lead to alopecia (hair loss) and permanent scarring.AbstractTinea capitis (TC) is a common cutaneous fungal infection in childhood. In this report, we describe the case of an 8-year-old child presenting with erythematous scalp lesions accompanied by hair loss. Upon examination, palpation revealed a swollen and tender left parotid gland. Notably, the frontal region of the scalp exhibited erythematous lesions and scaly red plaques resembling yellowish paste-like dough. Subsequent clinical evaluation and culture analysis confirmed the diagnosis of TC. The patient received treatment with Terbinafine 125 mg for a duration of 8 weeks. Follow-up examinations conducted after 3 months showed no signs of recurrence. Accurate diagnosis and timely treatment, along with adherence to medication regimens, are crucial in cases of TC, and differential diagnoses should be considered. Treatment should commence promptly upon diagnosis to prevent complications such as scalp baldness and transmission to others. This case report underscores the significance of establishing a precise diagnosis and effective treatment for this dermatophytosis to mitigate the risk of recurrences or therapeutic shortcomings, particularly in infants.Article Citation - WoS: 1The Unlikely Combination: Anderson-Fabry Disease and Congenital Dyserythropoietic Anemia Type Ii in a Pediatric Patient(Wiley, 2024) Elsherif, Yasmine; Ibrahim, Ismail A.; Elsherif, Omar; Abukhadijah, Hana J.Anderson- Fabry disease (AFD) is a rare condition, characterized by a lysosomal storage disorder affecting lipid storage. It manifests in two forms: classic (early- onset) and nonclassic (late- onset). Conversely, congenital dyserythropoietic anemia (CDA) is a rare blood disorder caused by ineffective erythropoiesis, which results in the production of abnormal erythroblasts during the maturation of red blood cells, with CDA type II being the most frequent type. Both disorders have well- understood pathophysiologies, yet they are genetically distinct. AFD is inherited in an X- linked manner, whereas CDA type II follows an autosomal recessive pattern of inheritance. Although both AFD and CDA type II have been reported separately in the literature. The co- existence for both AFD and CDA type II has not been reported. We describe a 10- year- old boy, with both which is believed to be the first documented case.Article Citation - WoS: 5Citation - Scopus: 5Disaster Risk Perception and Sustainable Earthquake Awareness Among Public and Private University Nursing Students(Wiley, 2024) Kolac, Nurcan; Eroglu, Nermin; Nirgiz, CansuBackground: This research was conducted in descriptive type to determine the disaster risk perception and sustainable earthquake awareness of nursing students studying at public and private universities. Methods: The study sample consisted of 400 nursing students studying at one public and one private university. The research was conducted between April and May 2023. The data were collected using a Sociodemographic Form, University Students Disaster Risk Perception Scale (USDRPS), and Sustainable Earthquake Awareness Scale (SEAS). Data were collected online using a questionnaire created on Google Forms. Analyses included frequency, percentage, mean, standard deviation values, independent groups t-test, post-hoc Tukey test, LSD, and ANOVA test. Results: Of the students, 61.8% had a disaster experience, 17.4% had lost a relative in the disaster, and 76.8% did not consider themselves prepared for a possible disaster. In the study, the exposure sub-dimension score of the disaster risk perception scale was found to be higher in students who had disaster experience than in those who did not (p = 0.032). Nursing students from the private university had higher sustainable earthquake awareness scores than those studying at the state university (p = 0.001). The mean scores of female students on the earthquake preparedness and preparation application sub-dimensions showed a significant difference compared to the scores of male students (p = 0.016). In the study, sustainable earthquake awareness total and earthquake preparedness sub-dimension scores were higher in second-year nursing students than in students of other years (p = 0.042; 0.015). Those who had received disaster training had low scores on the uncontrollable sub-dimension of the disaster risk perception scale, and high scores on the total SEAS and earthquake-structure relationship, earthquake preparedness, and earthquake preparation application sub-dimensions (p < 0.05). Conclusions: In the study, three out of four students did not find themselves prepared for disasters. Those who had disaster experience had higher disaster risk perceptions. Students who had received disaster-related training had more positive earthquake preparedness, earthquake-structure relationship, and earthquake preparation applications than those who had not. Students who were female and were in the second year had higher earthquake awareness. Studies can be carried out to inform people about the pre-disaster and preparation stages to raise awareness about disasters at universities. Education on disaster management can be integrated into courses from the first years of university.Article Citation - WoS: 1Functional Evaluation of Physical Performance, Gait, Balance and Activities of Daily Living in Older Individuals With Long Covid Syndrome(Wiley, 2024) Kosel, Izzettin; Aydin, Gamze; Tascilar Uyanik, Lacin Naz; Taşcilar Uyanik, Laçin NazObjective: The aim of our study was to evaluate the physical performance, balance, gait and activities of daily living (ADL) of older individuals with long COVID syndrome (LCS). Methods: A total of 124 individuals (49% women) with a mean age of 71.8 +/- 5.8 years were included in the study. Participants were divided into two groups, older individuals with LCS in the LCS group and older individuals who were not diagnosed with COVID-19 in the CON (control) group. Physical performance of participants was evaluated with the Alusti Test, balance and gait assessment was evaluated with the Tinetti Balance and Gait Assessment (TBGA), and ADL were evaluated with the Barthel Index (BI). Results: In the evaluations between groups, the mean score of active muscular mobility of right and left upper extremities, transfer supine position to sitting, trunk in sitting position and standing, which are among the subparameters of the Alusti Test, were statistically significantly lower in LCS compared to CON (p < .05). TBGA total score and gait section mean score of TBGA were statistically significantly lower in LCS than in CON (p < .05). There was no significant difference between the groups in the balance section of the TBGA and the mean BI scores (p > .05). Conclusions: It was concluded that physical performance parameters related to active muscular mobility of the upper extremity, transfer supine position to sitting, trunk in sitting position and walking in LCS were negatively affected by the disease, but this did not affect the level of balance and independence in ADL.Article Elastic Sac To Support Oral Feeding Performance of Preterm Infants: Crossover Randomized Controlled Study(Wiley, 2024) Genc, Canan; Goezen, Duygu; Narter, Fatma; Gözen, DuyguBackgroundSwaddling is recommended for preterm infants during feeding. Swaddling preterm infants with elastic cotton materials allows infants to easily stretch and move their extremities. This study aimed to assess the effect of bottlefeeding in a novel "elastic sac" on physiological parameters and feeding performance of preterm infants. MethodsA randomized controlled, crossover trial was conducted with total of 26 preterm infants at 26-36(+6) weeks of gestation. Infants randomly assigned to group 1 (n = 13) were bottlefed in an elastic sac (researcher-designed single-piece pouch made of soft, elastic cotton) for the first feeding and in normal clothes for the next feeding. Infants randomly assigned to group 2 (n = 13) were fed first in normal clothes and then in the elastic sac. The physiological parameters and feeding performance of the infants were assessed during each feeding. ResultsPreterm infants fed in the elastic sac had lower heart rate and higher oxygen saturation during and after feeding than infants fed in normal clothes (P < 0.05). Although all values were within clinically normal ranges, the findings suggest that feeding preterm infants in the elastic sac had a favorable effect on physiological parameters compared with feeding in normal clothes. There was no significant difference in the infants' feeding performance (P > 0.05). ConclusionA semielevated right lateral position and flexed body posture are recommended while feeding preterm infants, which can be easily maintained using the elastic sac. Feeding preterm infants in an elastic sac may support physiologic stability during oral feeding.Article Citation - WoS: 3Citation - Scopus: 3Which Factors Affect Internalized Stigmatization in Adolescents With Mental Disorders?(Wiley, 2022) Dikec, Gul; Bilac, Oznur; Kardelen, Cansin; Sapmaz, Sermin Yalin; Kandemir, HasanPurpose: The aim of this descriptive study was to determine the factors affecting internalized stigmatization of adolescents with mental disorders. Method: The study data were collected in a university hospital between August 1, 2020 and July 30, 2021 (n = 123), using a Personal information form and the Internalized Stigmatization of Mental Illness-Adolescent Form (ISMI-AF). Results: Gender and the number of hospitalizations were determined to be independent variables with explanatory power in the ISMI-AF, and in the model created with these variables, it was determined that these variables explained 18% of the change in the total points of the ISMI-AF. Conclusions: It could be recommended that psychosocial programs are developed with the aim of decreasing internalized stigmatization and increasing the psychological resilience of adolescents.Article Citation - WoS: 18Citation - Scopus: 21Exercise Improves Testicular Morphology and Oxidative Stress Parameters in Rats With Testicular Damage Induced by a High-Fat Diet(Wiley, 2022) Elmas, Merve Acikel; Ozakpinar, Ozlem Bingol; Kolgazi, Meltem; Sener, Goksel; Arbak, Serap; Ercan, FerihaObesity and male infertility are problems that affect population. Exercise is a nonpharmacological way to reduce the negative health effects of obesity. The purpose of this study was to examine the effects of exercise on hormone levels, blood-testis barrier, and inflammatory and oxidative biomarkers in rats that became obese due to a high-fat diet (HFD). Male rats received a standard diet (STD group) or a HFD (HFD group) for 18 weeks. During the final 6 weeks of the experiment, swimming exercises (1 h/5 days/week) were given to half of these animals (STD + EXC and HFD + EXC groups). Finally, blood and testicular tissues were analysed by biochemical and histological methods. Body weight, leptin, malondialdehyde, interleukin-6, TNF-alpha and myeloperoxidase levels, apoptotic cells and DNA fragmentation were increased, and testis weight, insulin, FSH, LH, testosterone, glutathione and superoxide dysmutase levels, proliferative cells, ZO-1, occludin, and gap junction protein Cx43 immunoreactivity were decreased in the HFD group. All these hormonal, morphological, oxidative and inflammatory biomarkers were enhanced in the HFD + EXC group. It is thought that exercise protected testicular cytotoxicity by regulating hormonal and oxidant/antioxidant balances and testicular function, inhibiting inflammation and apoptosis, as well as preserving blood-testis barrier.
