PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/8
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Article The Impact of Home-Based Telerehabilitation Pranayama on Sleep Quality and Wellbeing in Mild to Moderate Obstructive Sleep Apnea Syndrome. A Randomized Controlled Trial(BMC, 2026) Mustafaoğlu, Rüstem; Naci, Baha; Demir, Rengin; Önder, Ömer Önder; Atahan, Ersan; Kaçar Akkoç, ZeynepBackground Obstructive sleep apnea syndrome (OSAS) is a common disorder that causes repeated airway obstruction, disrupted breathing, and fragmented sleep. This study aimed to investigate the effects of Pranayama on sleep quality, daytime sleepiness, quality of life, fatigue, depression, and anxiety in patients with OSAS. Methods This study was designed as an open-label, prospective, randomized controlled trial. OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group or a Control group. Pranayama training was applied to the Intervention group for 8 weeks, 7 days a week, and 3 times a day for 15 min. In addition, a single 15-minute session, 3 days a week, was conducted online under the supervision of a physiotherapist. The control group did not receive any intervention. Primary outcome was sleep quality (Pittsburgh Sleep Quality Index, PSQ). Secondary outcomes included daytime sleepiness (Epworth Sleepiness Scale, ESS), Fatigue Severity Scale (FSS), Functional Outcomes of Sleep Questionnaire (FOSQ), Nottingham Health Profile (NHP), and Hospital Anxiety and Depression Scale (HADS). All outcome measures were assessed at baseline and reassessed after the 8-week intervention period. Results Thirty-eight OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group 6n = 19 ) or a Control group (n = 19) Four participants (two in each group) were lost to follow-up, leaving the data of participants (17 per group) available for inclusion in the final analysis. In the intervention group, PSQI scores decreased from 9.12 +4.71 to 6.88 +/- 4.45 (p < 0.001) whereas no improvement was observed in the control group. Regarding the primary outcome, the reduction in PSQI scores was significantly greater in the intervention group than in the control group (p < 0.001) The ESS scores also decreased significantly in the intervention group, from 9.41 +/- 6.15 to 7.41 +/- 6.18 6p = 0.006 with a significant between-group difference (p < 0.001) Fatigue severity decreased in the intervention group (FSS change: 0.53 +/- 0.70; p = 0.006 ), with a significant between-group difference 6p = 0.037 The FOSQ score improved markedly, with significant gains in FOSQ total score (-0.38 +/- 0.25 vs. 0.14 +/- 0.22 in controls; p < 0.001) and in activity level and vigilance subdomains (both p < 0.001). The HADS-anxiety scores decreased by 1.94 +/- 3.94 (p = 0.059) and depression scores by 3.06 +/- 2.05 (p < 0.001) in the intervention group, with significant between-group differences for both anxiety (p = 0.008) and depression (p < 0.001). Conclusion Pranayama was an effective adjunct therapy for these OSAS patients, and incorporating it into treatment strategies may enhance patient outcomes. Clinical trial registration number/date NCT04632147/22.10.2020.Article The Effect of Preoperative Melatonin Patches on Sleep Quality in Patients Undergoing Urological Surgery(Assoc Medica Brasileira, 2026) Akok, Selin Ayten; Akinci, Naile; Toprak, ÇağlaOBJECTIVE: The aim of this study was to determine the effects of transdermal melatonin patches on sleep quality in patients undergoing urological surgery. METHODS: This study is a randomized controlled trial. Fifty-seven patients hospitalized in the urology department of a university hospital in Istanbul were included. Patients were randomly assigned to two groups (melatonin and control). Patients in the melatonin group received transdermal melatonin containing 7 mg of melatonin at 11:00 PM in a quiet, darkened room the night before surgery. RESULTS: According to the results of this study, Richards-Campbell Sleep Scale sleep-quality scores increased significantly in the melatonin group (p<0.001). The control group showed lower sleep-quality scores. In addition, a statistically significant decrease was observed between the visual analog scale well-being scores before and after the application in the melatonin group (p<0.001). CONCLUSION: In this study, our results showed that melatonin patches improved sleep quality and psychological well-being in patients undergoing urological surgery.