PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/8
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Article The Impact of Home-Based Telerehabilitation Pranayama on Sleep Quality and Wellbeing in Mild to Moderate Obstructive Sleep Apnea Syndrome. A Randomized Controlled Trial(BMC, 2026) Mustafaoğlu, Rüstem; Naci, Baha; Demir, Rengin; Önder, Ömer Önder; Atahan, Ersan; Kaçar Akkoç, ZeynepBackground Obstructive sleep apnea syndrome (OSAS) is a common disorder that causes repeated airway obstruction, disrupted breathing, and fragmented sleep. This study aimed to investigate the effects of Pranayama on sleep quality, daytime sleepiness, quality of life, fatigue, depression, and anxiety in patients with OSAS. Methods This study was designed as an open-label, prospective, randomized controlled trial. OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group or a Control group. Pranayama training was applied to the Intervention group for 8 weeks, 7 days a week, and 3 times a day for 15 min. In addition, a single 15-minute session, 3 days a week, was conducted online under the supervision of a physiotherapist. The control group did not receive any intervention. Primary outcome was sleep quality (Pittsburgh Sleep Quality Index, PSQ). Secondary outcomes included daytime sleepiness (Epworth Sleepiness Scale, ESS), Fatigue Severity Scale (FSS), Functional Outcomes of Sleep Questionnaire (FOSQ), Nottingham Health Profile (NHP), and Hospital Anxiety and Depression Scale (HADS). All outcome measures were assessed at baseline and reassessed after the 8-week intervention period. Results Thirty-eight OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group 6n = 19 ) or a Control group (n = 19) Four participants (two in each group) were lost to follow-up, leaving the data of participants (17 per group) available for inclusion in the final analysis. In the intervention group, PSQI scores decreased from 9.12 +4.71 to 6.88 +/- 4.45 (p < 0.001) whereas no improvement was observed in the control group. Regarding the primary outcome, the reduction in PSQI scores was significantly greater in the intervention group than in the control group (p < 0.001) The ESS scores also decreased significantly in the intervention group, from 9.41 +/- 6.15 to 7.41 +/- 6.18 6p = 0.006 with a significant between-group difference (p < 0.001) Fatigue severity decreased in the intervention group (FSS change: 0.53 +/- 0.70; p = 0.006 ), with a significant between-group difference 6p = 0.037 The FOSQ score improved markedly, with significant gains in FOSQ total score (-0.38 +/- 0.25 vs. 0.14 +/- 0.22 in controls; p < 0.001) and in activity level and vigilance subdomains (both p < 0.001). The HADS-anxiety scores decreased by 1.94 +/- 3.94 (p = 0.059) and depression scores by 3.06 +/- 2.05 (p < 0.001) in the intervention group, with significant between-group differences for both anxiety (p = 0.008) and depression (p < 0.001). Conclusion Pranayama was an effective adjunct therapy for these OSAS patients, and incorporating it into treatment strategies may enhance patient outcomes. Clinical trial registration number/date NCT04632147/22.10.2020.Article Citation - WoS: 2Citation - Scopus: 1A New Perspective on Osas Cases With the Baveno Classification(Taylor & Francis Ltd, 2024) Koseoglu, Handan Inonu; Aykun, Goekhan; Kanbay, Asiye; Pazarli, Ahmet Cemal; Yakar, Halil Ibrahim; Demir, Osman; Inonu Koseoglu, HandanObjective/Background: Since the apnea-hypopnea index (AHI), which is used in the diagnosis and grading of OSAS, does not adequately reflect the clinical perspective of the disease, the Baveno classification of OSA was developed, which allows multicomponent evaluation of OSAS patients. The aim of our study was to evaluate the application of the Baveno classification in clinical practice. Patients/Methods: A prospective study was performed on patients diagnosed with OSAS between January 2021 and June 2022. Patients were divided into 4 groups according to Baveno classification (Groups A-D) and three groups as mild, moderate, and severe OSAS according to AHI. Results: A total of 378 patients (70% male, mean age 48.68 +/- 11.81 years) were included in the study. The patients had mild (n: 75; 20%), moderate (n: 88; 23%), and severe (n: 215; 57%) OSAS. According to Baveno classification, patients were included in Groups A (n: 90; 24%), B (n: 105 (28%), C (n: 65; 17%), and D (n: 118; 31%). The mean AHIs of the Baveno groups were similar (p = 0.116). Oxygen desaturation index (ODI) was higher in Groups B and D compared to Group A. The duration of T90 desaturation was longer in Groups C and D compared to Groups A and B (p < 0.05). Conclusions: The Baveno classification divided our OSAS cases into equivalent groups. One out of every four patients with mild OSAS was in Group D. This data was noteworthy in that the Baveno classification allows for the identification of symptomatic and comorbid patients with mild OSAS according to AHI and for the application of more effective treatments to these patients. Patients with comorbidities experienced oxygen desaturation for a longer period of time at night, and oxygenation deteriorated in patients with prominent symptoms. Baveno classification was found to be a more reasonable and easily applicable approach in clinical practice.