PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/8
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Article The Impact of Home-Based Telerehabilitation Pranayama on Sleep Quality and Wellbeing in Mild to Moderate Obstructive Sleep Apnea Syndrome. A Randomized Controlled Trial(BMC, 2026) Mustafaoğlu, Rüstem; Naci, Baha; Demir, Rengin; Önder, Ömer Önder; Atahan, Ersan; Kaçar Akkoç, ZeynepBackground Obstructive sleep apnea syndrome (OSAS) is a common disorder that causes repeated airway obstruction, disrupted breathing, and fragmented sleep. This study aimed to investigate the effects of Pranayama on sleep quality, daytime sleepiness, quality of life, fatigue, depression, and anxiety in patients with OSAS. Methods This study was designed as an open-label, prospective, randomized controlled trial. OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group or a Control group. Pranayama training was applied to the Intervention group for 8 weeks, 7 days a week, and 3 times a day for 15 min. In addition, a single 15-minute session, 3 days a week, was conducted online under the supervision of a physiotherapist. The control group did not receive any intervention. Primary outcome was sleep quality (Pittsburgh Sleep Quality Index, PSQ). Secondary outcomes included daytime sleepiness (Epworth Sleepiness Scale, ESS), Fatigue Severity Scale (FSS), Functional Outcomes of Sleep Questionnaire (FOSQ), Nottingham Health Profile (NHP), and Hospital Anxiety and Depression Scale (HADS). All outcome measures were assessed at baseline and reassessed after the 8-week intervention period. Results Thirty-eight OSAS patients meeting the inclusion criteria were randomly assigned to either an Intervention group 6n = 19 ) or a Control group (n = 19) Four participants (two in each group) were lost to follow-up, leaving the data of participants (17 per group) available for inclusion in the final analysis. In the intervention group, PSQI scores decreased from 9.12 +4.71 to 6.88 +/- 4.45 (p < 0.001) whereas no improvement was observed in the control group. Regarding the primary outcome, the reduction in PSQI scores was significantly greater in the intervention group than in the control group (p < 0.001) The ESS scores also decreased significantly in the intervention group, from 9.41 +/- 6.15 to 7.41 +/- 6.18 6p = 0.006 with a significant between-group difference (p < 0.001) Fatigue severity decreased in the intervention group (FSS change: 0.53 +/- 0.70; p = 0.006 ), with a significant between-group difference 6p = 0.037 The FOSQ score improved markedly, with significant gains in FOSQ total score (-0.38 +/- 0.25 vs. 0.14 +/- 0.22 in controls; p < 0.001) and in activity level and vigilance subdomains (both p < 0.001). The HADS-anxiety scores decreased by 1.94 +/- 3.94 (p = 0.059) and depression scores by 3.06 +/- 2.05 (p < 0.001) in the intervention group, with significant between-group differences for both anxiety (p = 0.008) and depression (p < 0.001). Conclusion Pranayama was an effective adjunct therapy for these OSAS patients, and incorporating it into treatment strategies may enhance patient outcomes. Clinical trial registration number/date NCT04632147/22.10.2020.Article Citation - WoS: 1Citation - Scopus: 1Can Manual Therapy Alter Muscle Stiffness in Patients With Spinal Accessory Nerve Injury(Wiley, 2025) Simsek, Ferhat; Naci, Baha; Kilicoglu, Meltem Bozaci; Alkan, Zeynep; Topcuoglu, Osman Melih; Gormez, Aysegul; Okyar, Ali FethiObjective. Shoulder and neck dysfunctions resulting from spinal accessory nerve injury impair quality of life. This study aims to investigate the effects of manual therapy in combination with standard physiotherapy on the mechanical properties of muscle, neck and shoulder function, pain, and quality of life in head and neck cancer patients. Study Design. Prospective, randomized, controlled, double-blind clinical trial. Setting. Department of Otorhinolaryngology Head and Neck Surgery of a university hospital. Methods. A total of 26 participants were randomized into two groups. The control group (n = 11) received standard physiotherapy including therapeutic exercises, scar tissue massage, and education. The intervention group (n = 10) received manual therapy consisting of soft tissue, myofascial release, and mobilization techniques in combination with standard physiotherapy. Outcome measures were mechanical properties of muscle, neck and shoulder active range of motion, shoulder pain and disability, and quality of life. Results. Upper trapezius and sternocleidomastoid muscle stiffness increased significantly in the control group (P < .01), whereas a significant reduction was observed in the intervention group compared to the control group (P = .001). A reduction in muscle thickness was observed bilaterally in both groups (P < .01). Moreover, all participants showed improvements in neck and shoulder active range of motion, shoulder pain, and quality of life (P < .01). Conclusion. Manual therapy in addition to standard physiotherapy was more effective in improving neck and shoulder function, quality of life, and reducing muscle stiffness compared to standard physiotherapy alone. Therefore, clinicians should consider incorporating manual therapy into their treatment protocols to optimize patient outcomes.Article Citation - WoS: 5Citation - Scopus: 5Effects of Adding Respiratory Training To Osteopathic Manipulative Treatment on Exhaled Nitric Oxide Level and Cardiopulmonary Function in Patients With Pulmonary Arterial Hypertension(Excerpta Medica inc-elsevier Science inc, 2022) Naci, Baha; Demir, Rengin; Onder, Omer O.; Sinan, Umit Yasar; Kucukoglu, Mehmet SerdarLimited research exists regarding nonpharmacologic management of pulmonary arterial hypertension (PAH), except for exercise training. The objective of this study was to investigate the effects of osteopathic manipulative treatment (OMT) alone and combined with respiratory training on fractional exhaled nitric oxide (FeNO), and cardiopulmonary function in patients with PAH. This single-blind, prospective, randomized controlled study included 54 patients with PAH who were randomly allocated to OMT, combined intervention, and control groups. The OMT group (n = 16) and combined intervention group (n = 16) received OMT and yoga respiratory training plus OMT, respectively, twice a week for 8 weeks. The control group (n = 16) received no intervention. All patients undertook an educational lecture. FeNO level, pulmonary function, 6-minute walk distance (6MWD), maximal inspiratory and expiratory pressures, and handgrip strength were assessed at baseline and 8 weeks. Combined intervention and OMT groups significantly improved all outcome measures after 8 weeks of treatment (p 0.01), except mean forced expiratory flow between 25% and 75% of forced vital capacity, which did not change in the OMT group (p 0.05). The control group showed significant deteriorations in 6MWD, inspiratory and peripheral muscle strength, and pulmonary function except peak expiratory flow at 8 weeks (p <0.05). The combined intervention group revealed significantly greater improvements of FeNO, 6MWD, respiratory and peripheral muscle strength, and pulmonary function except mean forced expiratory flow between 25% and 75% of forced vital capacity compared with the OMT group (p <0.05). All outcomes significantly improved in both intervention groups versus the control group (p <0.05). Our study demonstrated that adding respiratory training to OMT provided further benefit to FeNO level and cardiopulmonary function compared with OMT alone and that the OMT might be a useful and safe intervention for patients who cannot attend cardiac rehabilitation programs. (c) 2021 Elsevier Inc. All rights reserved. (Am J Cardiol 2022;162:184-190)