PubMed İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/8
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Article Oral Antipyretics for Fatigue Alleviation and Exercise Enhancement in Adults with Multiple Sclerosis: A Systematic Review and Meta-Analysis(Springer-Verlag Italia SRL, 2026) Hamdy, Ahmed Mohamed; Elmandrawi, Sara Wael; Ibrahim, Ismail A.; Shehata, Mazen Momtaz; Raza, Muhammad Liaquat; Elemam, Ahmed Mahmoud Elsayed; Elewa, MandyAims This review aims to explore the potential role of oral antipyretics (aspirin (ASA)/ acetaminophen), commonly known for fever and pain control, in managing fatigue, temperature regulation, and exercise capacity in patients with Multiple Sclerosis (MS), with a focus on nursing implications for symptom management. Design A systematic review of existing clinical studies assessing the effects of aspirin/ acetaminophen on MS-related fatigue, thermoregulation, and exercise performance. Data sources Electronic databases including Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, PubMed, Scopus, Web of Science, Wiley, Google Scholar, and ClinicalTrials.gov were searched up to March 2024. Review methods Quality assessment was conducted using the Cochrane risk of bias tool 2. to evaluate the methodological rigor of included studies. Outcomes analyzed included clinically assessed fatigue scores, exercise endurance, and postexercise thermoregulation, with attention to potential risks associated with aspirin use. Results After assessment of 57 reports for eligibility, only seven studies met inclusion criteria; results indicated that aspirin pretreatment significantly improved Time to Exhaustion (TTE) in heat-sensitive MS patients (p = 0.013), though one study reported no significant effect. Aspirin reduced post-exercise temperature rise by 56%, but this was not statistically significant in one trial (p = 0.178), while another showed significant reductions (p = 0.002). Conclusion Aspirin and acetaminophen may offer benefits in alleviating fatigue, enhancing thermoregulation, and improving exercise endurance in MS patients. These findings suggest that nurses should consider the potential role of aspirin in symptom management, with further research needed to confirm efficacy and safety. Impact This review highlights a potential adjunct therapy for nurses to incorporate into comprehensive MS care, emphasizing symptom control and quality of life improvements.Article Citation - WoS: 2Citation - Scopus: 1Examining the Sensory Processing Skills and Occupational Performance of People With Multiple Sclerosis(Taylor & Francis inc, 2024) Aydoner, Selen; Bumin, GoncaThis study aimed to compare sensory processing skills and occupational performance between participants with multiple sclerosis and healthy controls. Eighty participants were enrolled in this study, 40 with multiple sclerosis and 40 with healthy controls. Participants were between 18 and 65 years of age and asked to complete the Adult Sensory Profile, and Canadian Occupational Performance Measure. The findings of the study revealed that participants with multiple sclerosis had a lower ability to register sensory input, a higher sensory sensitivity, and avoidance, as well as lower levels of performance and satisfaction in their daily occupations, compared to the healthy controls (p < 0.05). People with multiple sclerosis often experience difficulties with sensory processing and occupational performance in daily life. More research and practice are needed on the role of sensory processing and occupational performance in daily life in people with multiple sclerosis.Article Citation - WoS: 3Citation - Scopus: 3E-Health Literacy Status of Individuals With Multiple Sclerosis in Turkey(Mary Ann Liebert, inc, 2024) Tosun, Anil Tekeoglu; Isiklar, Cagdas; Yildirim, Merve; Coskunsu, Dilber KaragozogluBackground: This research aims to compare e-health literacy of technology users and nonusers in people with multiple sclerosis (MS) and to investigate whether there are correlations between age, duration of MS, gender, marital status, and e-health total scores.Methods: This descriptive study was carried out with a web-based questionnaire. The questionnaire was sent to 300 patients with MS who were registered at Istanbul University-Cerrahpasa Medical Faculty Neurology Department.Results: A total of 156 people (mean age: 35.33 +/- 10.47 years) participated in the survey. Smartphone 98.1% (n = 153) was the mostly used device. Rate of using Google and recommended websites about MS was 94.25% (n = 145) and 73.9% (n = 113), respectively. e-Health literacy of both the tablet and recommended websites users significantly differed from that of nonusers (p = 0.007 for both). Participants' e-health literacy total score was found to weakly, but significantly, correlate with their age, marital status, and education level (rho: -0.161, p = 0.044; rho: 0.172, p = 0.032; rho: -0.192, p = 0.016, respectively).Conclusions: With developments in digital technologies, it is important to identify the access status of people with MS to improve daily clinical management and implement further motor and cognitive rehabilitation. Therefore, determining the health literacy of individuals with MS and providing education on this subject will reduce the information pollution.Article Citation - WoS: 4Citation - Scopus: 5Therapeutic Effects of Line Dancing in People With Multiple Sclerosis: an Evaluator-Blinded, Randomized Controlled Study(Routledge Journals, Taylor & Francis Ltd, 2024) Basturk, Sultan; Ekici, Gamze; Kirteke, Fatos; Durak, Omer Faruk; Ekici, BerkayBackgroundLine dancing is a popular form of exercise shown to affect balance and mood positively. However, few studies examine its effectiveness in multiple sclerosis (MS). The study aims to investigate the effects of line dancing on balance, mood, and health-related quality of life in MS.MethodsParticipants were randomized into the line dance (n =15) and the control groups (n =16). Outcomes were measured using the Berg Balance Scale, Hospital Anxiety and Depression Scale, and Multiple Sclerosis Quality of Life-54 (MSQoL-54) at baseline and post intervention.ResultsPost-intervention in the line dancing group, significant improvements were observed in balance, anxiety status, and health-related quality of life. When the groups were compared, significant differences were found in balance, anxiety, and the mental health composite of the MSQoL-54.ConclusionThis study recommends the use of line dancing as a therapeutic intervention in MS. Nevertheless, comparisons with different intervention approaches and follow-up studies are needed.Article Citation - WoS: 1Citation - Scopus: 1The Relationship Between Stress, Anxiety, and Depression Levels and Pseudobulbar Affect in Patients With Multiple Sclerosis(Routledge Journals, Taylor & Francis Ltd, 2022) Ozer, Duygu; Ata, Elvan Emine; Dikec, Gul; Demir, SerkanBackground Pseudobulbar affect (PBA) has recently been added to the list of mental disorders commonly observed in patients with Multiple Sclerosis (MS). The emotional changes experienced by MS patients may be associated with other mental problems and adversely affect disease prognosis. However, there are limited studies in the international and national literature on this subject. Aim This study aimed to evaluate the relationship between PBA and stress, anxiety, and depression levels in patients with MS. Design This is a descriptive, relational, and cross-sectional study. Methods A total of 442 MS patients followed in the neurology outpatient clinic of a hospital and registered with the MS Society in Turkey participated in this study. Data were collected using a personal information form, the Turkish version of the Center for Neurologic Study-Lability Scale (CNS-LS), and the Depression Anxiety Stress Scale (DASS). Results In this study, 63.3% of the patients had PBA, 21% had extremely severe depression, 41.6% had extremely severe anxiety, and 24.9% had severe stress. Correlation analysis revealed weak positive correlations between CNS-LS total score and DASS subscale and total scores. Depression, anxiety, and stress levels accounted for 22.5% of the variation in CNS-LS total score. Conclusion The results of this study indicate that a majority of MS patients in Turkey experience PBA, depression, anxiety, and stress, and that PBA is positively associated with depression, anxiety, and stress. Impact statement This study, indicates that should be increased consultation-liaison psychiatry services in Turkey, and MS patients should benefit from comprehensive psychiatric services.