Fenerbahçe Üniversitesi

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Citation - WoS: 1
Citation - Scopus: 1
A Comparative Study of Biochemical, Antimicrobial Effects and Phytochemical Composition Analysis of Glycyrrhiza Glabra L. Varieties Root Extracts
(Marmara University, 2025) Sen, Ali; Servı, Hüseyın; Barak, Timur Hakan; Tekin, Fethullah; Şener, Azize; Marzi, Mahdi; Gülmez, Gizem
Plants are the significant global interest as alternative treatment sources with their biologically activecompounds. This study compares the chemical composition and the antioxidant, antidiabetic, and antimicrobialproperties of ethanol extracts of G. glabra L. two different varieties from different regions. The phytochemicalcompositions was determined using GC-MS. Additionaly, total phenolic (TPC), flavonoid (TFC) and triterpene (TTC)contents were determined. Glycyrrhizic acid contents were analysed by HPLC. G. glabra var. glandulifera (GF1) showedthe highest antioxidant activity. All extracts had strong antidiabetic effects, besides GF1 showing the highest effect. TheMIC values was determined against 8 bacterial and 1 yeast strain and values ranged from 2.500 to 0.500; 2.500 to 0.714;2.500 to 0.714 for G. glabra var. glabra (GB), GF1, G. glabra var. glandulifera (GF2) respectively. Phytochemical studies haveshown that TPC was 100.60±5.06, 127.90±0.30, 69.01±0.30 mg GAE /g extract; TFC was 80.07±0.15, 25.35±0.0, 16.58±0.31mg KE/g and TTC was 217.30±6.05,172.40±2.17, 126.30±4.50 mg OE/g extract for GB, GF1, GF2, respectively. GF1 inparticular has the highest glycyrrhizic acid content. This study will contribute to the creation of new treatment strategiesand potential therapeutic agents in addition to the use of G. glabra L. in traditional treatments. Our study is also apreliminary study for future studies.
Citation - WoS: 8
Citation - Scopus: 9
Acute Changes in Electrophysiological Brain Dynamics in Elite Karate Players
(Springer international Publishing Ag, 2020) Duru, Adil Deniz; Balcioglu, Taylan Hayri; Ozcan Cakir, Canan Elif; Goksel Duru, Dilek
Regular physical exercise has enhanced effects on the human anatomy and functionality. Recently, an effect of a single set of exercise is shown to have positive effects on mood and on cognitive functioning. The aim of this study is to investigate the effect of a single bout of moderate exercise on the brain electrophysiological dynamics in resting-state condition and under the mental workload situation from elite-level athletes. For this purpose, electroencephalogram (EEG) is measured before and after the exercise sessions from 17 elite karate players who are members of the national karate team of Turkey. Blood lactate measurements are implemented to monitor the volunteers before EEG measurements. EEG data are analyzed using three metrics: conventional band power of each electrode, coherence metrics between electrodes for each band and source coherence values corresponding to each frequency band. Each metric is statistically analyzed between pre- and post-values, and results revealed that in all frequency bands, right parietal electrode had increased connection values which are thought to be related to ongoing sympathetic nervous system response observed during the recovery period. Another finding is the enhanced connectivity of frontal sources under the resting state as well as during the increased mental workload periods.
The Acute Effects of Various Dynamic Stretching Exercises on Jump Performance and Range of Motion
(Universidad de Murcia, 2025) Savaan, Mustafa; Pmar, Yeliz; Pmar, Salih
This study aimed to investigate the acute effects of different dynamic stretching (DS) protocols on vertical jump performance and range of motion (ROM). Thirty healthy male participants, with an average age of 23.48 years, body weight of 76.90 kg, and height of 181.87 cm, who had engaged in recreational exercise for at least two years, participated voluntarily. A "cross-controlled randomized" experimental design was utilized to assess four distinct DS protocols: a-DS at 100 bpm for 30", b-DS at 100 bpm for 75" s, c-DS at 150 bpm for 30", and d-DS at 150 bpm for 75". Acute ROM was measured using the Passive Straight Leg Raise Test (PSLR), while jump performance was assessed via countermovement jump (CMJ). Data were analyzed using repeated measures ANOVA and paired samples T-tests with significance set at p<.05. All four DS techniques significantly increased angles measured by PSLR following application (p <.05). CMJ values also showed significant improvements in both groups subjected to the shorter protocols lasting 30"at either tempo (p <.05). Consideration should be given to application duration and tempo when planning DS exercises, as structured warmup routines can enhance flexibility and optimize athletic performance.
Acute Serious Hepatitis of Unknown Cause in Children
(Galenos Publishing House, 2022) Kılbaş, E.P.K.; Altındiş, M.
On April 5, 2022, an increase in cases of acute hepatitis of unknown etiology was reported in previously healthy children under the age of 10 in the United Kingdom. Since there is no link between these patients, called acute non-HepA-E hepatitis, and viral hepatitis agents (hepatitis A, B, C, D, and E), the possible etiology, and pathogenesis of this emergency is being investigated. One of the alarming features of this epidemic is the high requirement for liver transplantation in a fraction of the cases. In cases other than hepatitis A, B, C, D, and E, a case definition is made by looking at a series of clinical pictures, including serum transaminase levels and age. As of August 26, 2022, 513 cases of acute hepatitis have been reported in Europe and 1,010 globally. Adenovirus was detected in 75% of cases tested in the UK, but data for other countries are still lacking. The role of other etiologic agents is still under investigation. The exact disease pathogenesis has not yet clear. Evidence of human-to-human transmission of the disease remains unclear. Epidemiological studies are critical in clarifying the uncertainties regarding the existence of links between the cases reported to date. Continuing the national and international surveillance activities of the countries in an organized manner is the most basic issue required for the elimination of the epidemic. Copyright © 2022 Tehran University of Medical Sciences.
Adaptation of Caregivers' Task Scale for Multiple Sclerosis To Turkish Society: Validity and Reliability Study
(Dokuz Eylul Univ inst Health Sciences, 2022) Eroglu, Nermin; Tosun, Anil Tekeoglu
Objectives: This study was planned and carried out methodologically to adapt the Caregiving Tasks in Multiple Sclerosis Scale (CTiMSS) to Turkish society. Methods: A methodological research. The study was conducted with caregivers of individuals with multiple sclerosis who presented to the neurology clinic of a university hospital between June 2019 and September 2020. The validity and reliability study of the Caregiving Tasks in Multiple Sclerosis Scale (CTiMSS) was performed with a total of 142 individuals, which is more than 5 times the number of items on the scale (24 items). Results: The validity of the CTiMSS was evaluated with language validity, construct validity (CFA), and content validity. The reliability coefficient of the internal consistency analysis (Cronbach's Alpha) was found to be extremely high (0.97). Item-total correlation of the scale was examined, and accordingly, no items were removed from the scale. The scale was administered to 30 patients at a two-week interval to analyze test-retest reliability and time-dependent invariance. Conclusion: The CTiMSS, which was adapted to Turkish society to evaluate the tasks of individuals providing care for individuals with multiple sclerosis, is a valid and reliable tool. We recommend that it should be administered to different groups and cultures to increase its evidence value. CTiMSS is an appropriate measurement tool to determine the duties of caregivers of individuals with multiple sclerosis.
Citation - WoS: 1
Ameliorative Effects of Myrtus Communis L. Extract Involving the Inhibition of Oxidative Stress on High Fat Diet-Induced Testis Damage in Rats
(Taylor & Francis Ltd, 2024) Coskunlu, Busra; Koroglu, M. Kutay; Hersek, Irem; Ertas, Busra; Sen, Ali; Sener, Goksel; Ercan, Feriha
The possible protective effects of Myrtus communis L. (MC) extract on a high fat diet (HFD)-induced testicular injury in a rat model were investigated using histological and biochemical methods. Wistar albino rats were divided into three groups: a standard diet control group; a HFD group; and an HFD+MC group. The HFD and HFD+MC groups were fed with a HFD for 16 weeks. MC extract (100 mg/kg) was given orally five days a week to the rats in the HFD+MC group during the last four weeks of the experiment. Leptin, triglyceride, high-density lipoproteins, cholesterol, estrogen, testosterone, LH and FSH were analyzed in blood serum. Sperm parameters were evaluated from the epididymis. Testicular morphology, proliferative, apoptotic and NADPH oxidase-2 (NOX2)-positive cells were evaluated histologically. Testicular oxidative stress parameters were analyzed biochemically. In the HFD group, lipid and hormone profiles were changed, abnormal spermatozoa, degenerated seminiferous tubules with apoptotic and NOX2-positive cells were increased in number, and sperm motility and germinal proliferative cells decreased compared to the control group. Moreover, testicular malondialdehyde, 8-hydroxy-2-deoxyguanosine and myeloperoxidase levels increased, whereas glutathione and superoxide dismutase levels decreased in the HFD group compared to the control group. All these histological and biochemical features were ameliorated by MC treatment of HFD-fed rats. In conclusion, HFD caused alterations in sperm parameters and testicular morphology by increasing oxidative damage and apoptosis. MC extract may have potential protective effects by inhibiting oxidative damage.
Citation - WoS: 3
Citation - Scopus: 5
Analysis for Two-Dimensional Inverse Quasilinear Parabolic Problem by Fourier Method
(Taylor & Francis Ltd, 2021) Kanca, Fatma; Baglan, Irem
In this work, two-dimensional inverse quasi-linear parabolic problem with periodic boundary and integral overdetermination conditions is investigated. The formal solution is obtained by the Fourier approximation. Under some natural regularity and consistency conditions on the input data,the existence, uniqueness and continuously dependence upon the data of the solution are proved by iteration method. The inverse problem is first examined by linearization and then used implicit finite difference scheme for the numerical solution. Also predictor corrector method is considered in the numerical approach. Some results on the numerical solution with two examples are presented with figures and tables. The sensitivity of the scheme with respect to noisy overdetermination data is illustrated.
An Analysis of Psychological Resilience Levels Among Judo Coaches According to Selected Demographic Factors
(Idokan Poland Association, 2025) Beşiktaş, M.Y.; Terekli, M.S.
Background. Psychological resilience is a crucial personal trait that enables individuals, especially those in high-stress professions like coaching, to adapt and thrive in the face of adversity. Understanding how resilience manifests among coaches can contribute to more effective support and development strategies in sports psychology. Problem and aim. This study aims to determine whether the psychological resilience levels of judo coaches differ according to demographic variables such as age, educational background, coaching certification level, years of coaching experience, profession, and perceived economic status. Material and methods. The sample included 284 active judo coaches (58 women and 226 men) from Istanbul, Kutahya, and Eskisehir. Data were collected using the “Psychological Resilience Scale for Adults” [Friborg et al. 2003; Basim, Cetin 2011] and a “Personal Information Form.” Statistical analyses were conducted using SPSS 24.0, including independent samples t-tests, one-way ANOVA, and Eta squared analysis to assess the influence of demographic actors on resilience levels. Results. The findings indicated significant differences in psychological resilience levels based on gender, marital status, age, educational attainment, coaching experience, income level, and coaching certification level. Conclusions. The results suggest that psychological resilience among judo coaches is meaningfully influenced by various demographic characteristics. These findings underscore the importance of tailoring psychological support and development programs to the specific profiles of coaches. © Yoshin Academy
Citation - WoS: 1
An Analysis of the Gross Motor Skills of Children Aged 3-6 Years With Autism Spectrum Disorder in Comparison With Their Typically Developing Peers
(Sagamore Publishing Llc, 2023) Ozcan, Gulsum Hatipoglu; Ozer, Dilara; Pinar, Salih
The aim of this study is to examine the motor skill levels of children aged 3-6 years with Autism spectrum dis-order (ASD) in comparison with their typically devel-oping (TD) peers and to reveal their needs for motor support programs. The research group consisted of 88 participants aged 3-6 years, including 43 children (40 boys and 3 girls) diagnosed with ASD attending spe-cial education and rehabilitation institutions, and 45 TD children (23 boys and 22 girls) receiving pre-school education in a private institution (ASD=57.4 months, +/- 9.32 - TD=59.06 months, +/- 8.61). The Peabody Devel-opmental Motor Scale-2 (PDMS-2) and the Turkish Ver-sion of the Gilliam Autism Rating Scale-2 (GARS-2-TV) were used as data-collection tools in the study. The Mann-Whitney U test was used for the two-group com-parisons of the parameters that did not exhibit normal distribution in the analysis of the data. The Spearman correlation analysis was applied to determine the relationship between the variables. The significance was evaluated at the p<0.05 level. As a result of the research, the balance, locomotor and manipula-tive skills and total gross motor scores of the children with ASD were found to be lower than those of the TD children (p<0.05). In addition, it was observed that there was a significant correlation between GARS-2 -TV scores and PDMS-2 scores of the children with ASD (p<0.05).
Citation - WoS: 1
Citation - Scopus: 2
Apocynin Exhibits an Ameliorative Effect on Endothelial Dysfunction/ Atherosclerosis-Related Factors in High-Fat Diet-Induced Obesity in Rats
(Marmara Univ, Fac Medicine, 2024) Ayci, Nurdan Bulbul; Ertas, Busra; Kaya, Rumeysa Keles; Sevinc, Sevgi Kocyigit; Amuran, Gokce Gullu; Ercan, Feriha; Cetinel, Sule
Objective: The aim of this study was to reveal the effect of apocynin (APO) on the factors involved in obesity-related endothelial dysfunction (ED) and atherosclerosis (AS). Materials and Methods: Male Wistar albino rats were divided into control (CNT), high-fat diet (HFD) and HFD+APO groups. HFD and HFD+APO groups were fed HFD for sixteen weeks. APO (25 mg/kg) was administered to the HFD+APO group for the last four weeks. The effects of APO on: AS-related metabolic parameters (triglyceride, total cholesterol, high-density lipoprotein-cholesterol, insulin and leptin), oxidative stress (OS), [ malondialdehyde, glutathione, nicotinamide adenine dinucleotide phosphate (NADPH)oxidase-2, oxidised-low-density lipoprotein (ox-LDL) and 8-hydroxy-2-deoxyguanosine], low-density lipoprotein and ox-LDL uptake potential (activin receptor-like kinase-1 and lectin-like oxidized low-density lipoprotein receptor-1, respectively), tissue inflammation inducible-nitric oxide synthase, nitric oxide), programmed cell death (terminal deoxynucleotidyl-transferase-dUTP-nick-end (alpha-smooth muscle actin), histology and ultrastructure of thoracic aorta were evaluated. Results: In obesity, APO had an ameliorative effect on metabolic parameters, OS, inflammation, ED, programmed cell death and oxLDL uptake potential, but not on foam cell formation and LDL uptake potential. Conclusion: Apocynin may improve ED and AS in obesity by suppressing OS-linked factors involved in the early stage of AS.
Assessment of Breastfeeding Self-Efficacy in Nursing Mothers Following Earthquakes: A Case Study of the Kahramanmaraş Earthquakes in Turkey
(Kashan Univ Medical Sciences, 2025) Dinmez, Sinem Guven; Karaman, Ozen Esra; Bakir, Emine
Background: Natural disasters disproportionately impact vulnerable populations, particularly mothers and infants. Research indicates that during such events, mothers often favor formula and supplementary feeding over breastfeeding. Self-efficacy is a critical determinant influencing breastfeeding practices in disaster contexts.
Objectives: This study aimed to examine the breastfeeding characteristics and self-efficacy of nursing mothers following the Kahramanmara & scedil; earthquakes.
Methods: This descriptive study was conducted at the Children's Polyclinic of Iskenderun State Hospital in Turkey from August 1 to August 31, 2023. A total of 54 mothers with infants aged 0-1 year at the time of the earthquake, who continued to breastfeed (providing breast milk for at least one feeding), were selected using a non-probability purposive sampling method. During the study period, all eligible mothers visiting the polyclinic who met the inclusion criteria were evaluated. Data were collected using a "Descriptive Data Form" and the "Breastfeeding Self-Efficacy Short Form Scale". Statistical analyses were performed using SPSS version 23, employing Independent Samples t-tests, Mann-Whitney U tests, and One-Way ANOVA for group comparisons. A P-value of less than 0.05 was considered statistically significant.
Results: The mean breastfeeding self-efficacy score among mothers was 58 +/- 5.87 (minimum 40; maximum 70). Mothers who exclusively breastfed their infants had significantly higher self-efficacy scores compared to those who introduced formula (P = 0.021) Among the mothers surveyed, 81.5% reported that their breastfeeding was affected by the earthquake; 41% cited issues related to privacy, while 27% faced challenges regarding shelter. Prior to the earthquake, 72% of infants were exclusively breastfed; however, this figure decreased as 81.5% of infants began receiving complementary foods alongside breast milk post-earthquake.
Conclusion: The findings indicate that mothers breastfeeding self-efficacy is at a moderate level. Additionally, mothers reported alterations in their breastfeeding practices compared to the pre-earthquake period. These results underscore the importance of promoting breastfeeding in disaster-affected areas and highlight the critical role of midwives in supporting these efforts.
Citation - WoS: 1
Citation - Scopus: 1
Assessment of the Psychometric Properties of the Online Education Student Satisfaction Scale: a Methodological Study
(Springer Publishing Company, 2024) Harmancı Seren, A.K.; Alan, H.; Türkmen, E.; Gungor, S.; Baykal, Ü.
Background and Purpose: Assessing student satisfaction is essential in evaluating the quality of education. The number of valid and reliable tools that measure students’ satisfaction with online education is limited. This methodological study aimed to assess the psychometric properties of the online education student satisfaction scale. Methods: Eleven academicians from the nursing field provided expert opinions on content validity. Separate 25 students evaluated the language clarity of the draft scale. The study sample included 525 third- and fourth-year nursing students. Finally, a group of 30 nursing students different from the sample participated in the test–retest. The study created an item pool based on the recent literature. The researchers calculated the items’ content validity rates and the scale’s content validity index by taking the experts’ opinions. In addition, item–total score correlation analysis, exploratory factor analysis, discrimination analysis, stability test, and internal consistency analysis were performed. Results: An item with a low-correlation value was excluded from the scale. The correlation coefficients of the remaining items were between.536 and.811. In the second round of exploratory factor analysis, a five-factor structure emerged that explained 72.1% of the total variance. In addition, item discrimination, stability, and internal consistency test results ensured that the scale was valid and reliable. Conclusions: The online education student satisfaction scale with five subdimensions containing 28 items is a valid and reliable tool. Researchers, educators, and managers may use it to evaluate students’ satisfaction with online education. © Copyright 2024 Springer Publishing Company, LLC.
Assessments of Energy, Macro and Micronutrient Intakes in Children and Adolescents With Type 1 Diabetes Mellitus
(Marmara Univ, Fac Medicine, 2023) Ozkaya, Volkan; Ozkaya, Sebnem Ozgen
Objective: This study aims at examining dietary intake in children and adolescents with type 1 diabetes mellitus (DM) and comparing the results with national dietary intake recommendations. Patients and Methods: One hundred fifty children and adolescents (52.7% female) with an average age of 12.2 +/- 3.1 years and with type 1 DM who were followed by the Pediatric Endocrinology Polyclinic participated in the study. Three-day food intake records and clinical information regarding the type 1 DM condition of the participants were obtained. Results: No gender-related significant difference was found among the participants regarding food intake. The percentage of energy derived from fat (average 39.6%) and saturated fat (16.1%) were higher than the recommended levels in both gender groups. The percentage of energy derived from carbohydrates (female 44.1 +/- 5.7%, male 43.0 +/- 6.8%) was below the recommended levels. The dietary fiber intake in children aged 6-10 years with type 1 DM met recommendations, whereas, it was below the recommended levels in other age groups. Micronutrient inadequacy was common in children and adolescents with type 1 DM. Conclusions: The authors believe that guidelines and programs are needed for children and adolescents with type 1 DM to reduce total fat and saturated fat intake, increase carbohydrate and dietary fiber intake up to the recommended levels, and prevent multiple micronutrient inadequacies.
Citation - WoS: 3
Citation - Scopus: 5
Association Between Carbohydrate Quality Index and Dietary Patterns, Sleep Quality, Anxiety Level, and Depression Symptoms: a Cross-Sectional Study
(Soc Chilena Nutricion, Bromatologia & Toxicologia, 2022) Yuksel, Aysun; Yilmaz-Onal, Hulya; Basturk, Berrak; Yalcin, Bahar
Aim: This study was conducted to determine the relationship between carbohydrate quality and sleep quality, depression, anxiety, stress and anthropometric measurements. Methods: The carbohydrate quality was calculated using the total fiber intake, ratio of whole grains to total grains, the ratio of solid carbohydrates to total carbohydrates, and the glycemic index. Sleep status was determined using the Pittsburgh Sleep Quality Index (PSQI) and nutritional status was determined by taking a 1-day food consumption record and food consumption frequency. Results: It was found that 20% of the participants with the highest carbohydrate quality had the highest sleep quality and the lowest body mass index. Conclusion: Adults should be informed that the quality of carbohydrates that they consume, was associated with better sleep quality and some micronutrients (potassium, magnesium, vitamin A-D-K-C-81-86, Folate) but no significant correlation was found between anxiety, depression, and stress scores
Bangladesh Journal of Pharmacology
(Bangladesh Pharmacological Soc, 2024) Kulabas, Necla; Guven, Cansu Tamniku; Duracik, Merve; Ozakpinar, Ozlem Bingol; Kucukguzel, Ilkay
[No Abstract Available]
Citation - WoS: 5
Citation - Scopus: 7
Bitter Melon (Momordica charantia) Fruit Extract Ameliorates Methotrexate-Induced Reproductive Toxicity in Male Rats
(Marmara University, 2021) Kanpalta, Fatma; Özbeyli, Dilek; Sen, Ali; Cevik, O. Dağdeviren; Şener, Göksel; Ercan, Feriha
Objective: Methotrexate (MTX) is a drug commonly used for the treatment of malign neoplastic and inflammatory diseases. Anti-oxidant and anti-inflammatory effects of bitter melon (BM) were reported. The aim of this study was to examine the effects of BM fruit extract on MTX-induced testicular and epididymal damage. Materials and Methods: Sprague Dawley male rats were divided into three groups (n=8) as control, MTX and MTX+BM. A single dose of MTX (20 mg/kg) was injected intraperitoneally to the MTX and MTX+BM groups. BM fruit extract (600 mg/kg) was applied to the MTX+BM group orally for 5 days. Testes were examined for general histopathology, proliferating and apoptotic cells. The epididymis samples were used for the evaluation of sperm morphology. Oxidative and inflammatory markers were analysed biochemically. Results: Increased abnormal spermatozoa, degenerated seminiferous tubules with increased apoptotic cells and decreased proliferative cells were observed in the MTX group. TNF-α, IL-1β, 8-hydroxy-2-deoxyguanosine and caspase-3 levels increased, superoxide dismutase and catalase levels decreased in both testis and epididymis samples. All these histological and biochemical parameters were ameliorated in the MTX+BM group. Conclusion: Methotrexate causes testis damage by decreasing spermatogenic cells and increasing apoptosis through oxidative stress and inflammation. BM extract improves testis and epididymis damage with its possible anti-oxidant and anti-inflammatory effects. © 2025 Elsevier B.V., All rights reserved.
Brain in Metabolic Syndrome Model: the Effect of Exercises and Caloric Restriction
(Marmara Univ, 2022) Alev-Tuzuner, Burcin; Genc-Kahraman, Nevin; Ipekci, Hazal; Ustundag, Unsal Veli; Tunali-Akbay, Tugba; Emekli-Alturfan, Ebru; Yarat, Aysen
Caloric restriction (CR) and exercise (EX) have impacts on improving metabolic risk factors. This study aimed to investigate the changes in the brain after EX and/or CR in metabolic syndrome (MeS) induced by a high fructose diet in rats. Sprague-Dawley male rats were divided into five groups. Drinking water including 10% fructose solution was given to rats for 12 weeks to develop a MeS rat model. Animals with MeS were submitted to EX and/or CR for 6 weeks. Blood glucose, and brain tissue damage and antioxidant parameters were measured. Brain lipid peroxidation, sialic acid, mucin, fucose levels increased in the MeS group compared to the control (C) group. These parameters reduced significantly in the metabolic syndrome with caloric restriction (MeS+CR) group, and more significantly in the metabolic syndrome with exercise and caloric restriction group (MeS+EXCR), compared to the MeS group. Glutathione levels, superoxide dismutase and catalase activities decreased in the MeS group compared to the C group, increased both in the MeS+CR group, and MeS+EXCR group compared to the MeS group. High fructose diet consumption can lead to brain tissue damage and decreased antioxidant levels were found to be improved best in the MeS+EXCR group.
Canlı Karaciğer Donör Adaylarında Hepatosteatozun Saptanmasında Biyopsi, Bilgisayarlı Tomografi ve Manyetik Rezonans Görüntülemenin Karşılaştırılması
(2021) Sokmen, Bedriye Koyuncu; Şahin, Tolga; Koçak, Erdem; Oral, Alihan
Amaç: Karaciğer donöründe hepatosteatoz (HS) varlığı, karaciğer transplantasyonu sonuçları üzerinde olumsuz etkilere sahiptir. Bu nedenle, donörde HS’nin tespiti, nakil öncesi dönemde hayati önem taşımaktadır. Bu çalışmanın amacı, canlı karaciğer donör adaylarında HS’nin saptanmasında karaciğer biyopsisi ve radyolojik yöntemlerin etkinliğini karşılaştırmaktır. Gereç ve Yöntem: Demiroğlu Bilim Üniversitesi’ne karaciğer transplantasyonu için donör adayı olarak kabul edilen 226 sağlıklı birey çalışmaya dahil edildi. Donörlerin demografik, histopatolojik, laboratuvar ve görüntüleme bulguları retrospektif olarak incelendi. Donörlerin bilgisayarlı tomografi (BT) ve manyetik rezonans görüntüleme (MRG) taramaları geriye dönük olarak yeniden değerlendirildi ve karaciğer yağ ölçümleri kaydedildi. Bulgular: Hastaların %39’u (88) kadın, %61’i (138) erkekti. Çalışma popülasyonunda ortalama yaş 34,3±8,7 yıl, ortalama ağırlık 78,0±12,6 kg, ortalama boy 169,1±9,6 cm ve ortalama vücut kitle indeksi 27,2±4,0 idi. Karaciğer biyopsisinde donörlerin %42’sinde <%5 HS vardı ve donörlerin %58’inde >%5 HS vardı. Hem BT hem de MRG, HS saptamada biyopsi ile anlamlı korelasyon gösterdi (p<0,05). Sonuç: Çalışmamızda MRG’nin BT kadar biyopsi ile ilişkili olduğu ve HS’nin saptanmasında rahatlıkla kullanılabileceği bulunmuştur. Karaciğer donörlerinde MRG kullanımı, iyonizan radyasyon içermemesinden dolayı nakil öncesi donör için daha uygun bir yöntem olabilir.
The Challenges Experienced by International Nursing Students in Nursing Education: a Qualitative Study
(Ataturk Univ, 2024) Elmali Simsek, Hulya; Karali, Ece; Arslan, Gunay
Objective: The study aimed to determine the challenges experienced by international nursing undergraduate students during their education period. Methods: A phenomenological research design was used. The study was conducted with 20 international nursing students enrolled in a foundation university in T & uuml;rkiye. Colaizzi's phenomenological data analysis method was employed in the study. Results: Based on the study's results, three main themes, 'Learning in a different environment', 'Challenges', 'Solution-Non Solution' and 'System difference, Language problems in clinical practice, Broad nursing curriculum, Facilitators, Language barrier, Feeling homesick, Racism and discrimination, Housing difficulties, Lack of funding, Instant solution, Failing to find a solution sub-themes themes were created. Conclusion: It has been observed that students experience different environments, uncertainties, and various challenges, and that these situations directly affect their education and success. To that end, both the institutions they receive education and the academicians must support the students in various ways.
Citation - WoS: 1
Chatgpt as a Solution To Emotional Loneliness: a New Tool for Interpersonal Communication
(Marmara Univ, Fac Communication, 2024) Sarioglu, Elif Basak; Guregen, Esra Pelin
Loneliness stands as one of the most pervasive and universal health issues in contemporary society. This study, conducted within the scope of emotional loneliness, delves into the nuances of loneliness, understanding its origin and how it manifests in individuals. In the research where students from the Faculty of Communication of a foundation university in Istanbul were chosen as the sample, the data collected through in-depth interviews, a qualitative data collection tool, were analyzed using content analysis method. This phenomenological research design aimed to assess participants' attitudes toward utilizing a chatbot (ChatGPT) as a tool to combat emotional loneliness. Despite their generally positive disposition and strong tendency to anthropomorphize, participants were found to approach the use of ChatGPT with caution. The majority harbored negative judgments about ChatGPT and technological tools meeting emotional and social needs. However, a significant portion believes that the widespread adoption of ChatGPT and similar tools for socialization is imminent in the near future. Concerns predominantly revolve around mistrust in artificial intelligence technologies' ability to meet emotional needs and the potential harms they could inflict on socio-cultural life, with ethical issues forming another major theme. Notably, when expressing their apprehensions, participants frequently referenced artificial intelligence representations in popular culture, such as films, series, and games.

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