Scopus İndeksli Yayınlar Koleksiyonu
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Article Citation - WoS: 3Citation - Scopus: 5Analysis for Two-Dimensional Inverse Quasilinear Parabolic Problem by Fourier Method(Taylor & Francis Ltd, 2021) Kanca, Fatma; Baglan, IremIn this work, two-dimensional inverse quasi-linear parabolic problem with periodic boundary and integral overdetermination conditions is investigated. The formal solution is obtained by the Fourier approximation. Under some natural regularity and consistency conditions on the input data,the existence, uniqueness and continuously dependence upon the data of the solution are proved by iteration method. The inverse problem is first examined by linearization and then used implicit finite difference scheme for the numerical solution. Also predictor corrector method is considered in the numerical approach. Some results on the numerical solution with two examples are presented with figures and tables. The sensitivity of the scheme with respect to noisy overdetermination data is illustrated.Book Challenging Discrimination in Different Areas: Turkey(Peter Lang AG, 2021) Akincilar Köseoğlu, N.; Apak, D.This book aims to evaluate the issue of discrimination in Turkey from different points of view. Valued academics have addressed issues of discrimination in different fields such as press, sports media, social media, politics, political discourse, immigration, economics, architecture, gender, identity, and violence. Turkey is also encountered in both implicit and explicit examples of discrimination in a way as it is in many other countries. Discrimination can be adopted through discourses and can be reproduced in a wide range from politics to sports, from media to economy and can also be carried over generations. Although legal arrangements have been made against discrimination, discrimination is still active in different parts of society and in different areas. © Peter Lang GmbH Internationaler Verlag der Wissenschaften Berlin 2021.Conference Object Classification of Noisy Histopathology Images with Bayesian and Ensemble Deep Learning(SPIE, 2025) Akturk, B.; Bilgin, G.The classification of histopathology image data using deep learning algorithms is a pivotal aspect in cancer diagnosis, offering crucial benefits in terms of accuracy and rapid decision-making for pathologists, technologists, clinicians, and researchers. However, the complex process of data structuring and labeling often involves the presence of noisy or outlier labels and images, which inevitably diminish the training and predictive efficacy of classification models. This study introduces an innovative approach for classifying histopathology images with noisy characteristics, presenting a learning process resilient to noise. In this dataset, where classification performance is inherently challenged, popular transfer learning models are integrated with Bayesian deep learning and ensemble learning algorithms. This integration helps mitigate common problems such as overfitting and underfitting in outlier data predictions, yielding more stable outcomes. These hybrid methods, unaffected by the noise and uncertainty in data structures, demonstrate performance comparable to, or even surpassing, transfer learning algorithms. Consequently, the viability of addressing real-world noisy dataset scenarios is enhanced. Experimental results indicate that the proposed ensemble Bayesian transfer learning algorithms match the success of pre-trained transfer learning algorithms and offer an alternative to time-consuming model validation techniques, underscoring the practical application of ensemble Bayesian transfer learning in enhancing uncertainty assessments. · © 2025 SPIE · 0277-786X ·Article Comprehensive Proteomic and Metabolomic Analysis of Novel Substituted Fluoroquinolone Derivatives in Escherichia Coli Isolates(John Wiley and Sons Ltd, 2026) Nigiz Ş.; Kulabaş N.; Türe A.; Kablan S.; Koçak E.; Özkul C.; Küçükgüzel İ.Antimicrobial resistance is one of the most important global problems, and new antibiotic requirements have been emerging as a key point in this issue. In the present work, we focused on the efficiency of two novel promising fluoroquinolone derivatives on resistant Escherichia coli isolates at the molecular level. Their mode of action and adaptation process were evaluated by using proteomics and metabolomics analysis. Proteomics analysis showed that two compounds have an effect mainly on the ribosomal process and energy metabolism. Moreover, we observed compounds that affect various important antimicrobial targets, such as ribosomal subunits, phosphotransacetylase, and chaperone proteins. In metabolomics analysis, we found that compounds altered bacterial metabolism directly. Pathway analysis showed that cofactor biosynthesis and energy metabolism were affected mainly by undertreated groups. Our experiments demonstrated that novel fluoroquinolone derivatives have promising results at the molecular level and results will contribute to further studies. © 2026 John Wiley & Sons Ltd.Conference Object Citation - WoS: 1Citation - Scopus: 1Design and Development of a New Tactile Stimulator(Ieee, 2019) Kazma, Coskun; Levent, Vecdi Emre; Aydin, NizamettinWe have designed and implement a tactile stimulator to obtain information from the central nervous system. Our system consists of two main components. The first one is tactile stimulator, which was designed to stimulate index and middle finger tips, stimulating mechanoreceptors according to the test protocol. Second one is a personal computer running a desktop software for the implementation of test protocols. The flow is as follows; the subjects are asked the question of the test protocol through the personal computer. The parameters are then transmitted to the embedded board on the machine. The embedded board drives step motors to apply the relevant test parameters. The desktop software expects the individual to answer the question using the right or the left mouse button of the computer mouse. After answering the relevant question, the test proceeds to the next step. According to the test protocol, the stimulation process of the mechanoreceptors located at the index and middle finger tips must start and terminate at the same time. From this perspective, the embedded board with 3 18F46K22 PIC microcontrollers produces 2 square wave signals with different frequencies and amplitudes at the same time. The embedded system card developed with the PIC microcontroller is also developed with FPGA. The system has also been tested on 24 blue and white collar employees and a significant result has been obtained.Article The Destruction of a Generation by War: Syrian Families, Children’s Education, and the Risks for Turkey(Dr. Esmeralda F. Sanchez, 2025) Terekli, M.S.; Beşiktaş, M.Y.This study examines the phenomenon of migration, focusing on Syrian families under temporary protection who migrated to Turkey following the mass movement of people from Syria after 2011. The research explores the education of Syrian children and the risks faced by Turkey in this context. It also evaluates the economic, social, and cultural impacts of the Syrian refugee crisis on Turkey, highlighting both its positive and negative aspects, as well as related security concerns. Syrian children require increased access to psychological and psychiatric healthcare services. However, many are forced to work under harsh conditions as cheap labor. The employment rates of these children, categorized by age groups, exhibit similarities to those in Turkey but differ significantly from global trends. Applying these observations to Turkey, this study discusses the stages of educational services provided to Syrian children and suggests practical recommendations to improve their quality. The findings reveal that although Syrian children increasingly benefit from educational services each year, their participation rates remain below Turkey's national average. The study also highlights deficiencies in education, healthcare, employment, and socioeconomic conditions for children under temporary protection. Predictably, migration flows intensify during periods of intense conflict. Data from international organizations such as the United Nations High Commissioner for Refugees (UNHCR) and the International Organization for Migration (IOM) have been utilized in this research. © 2025 Elsevier B.V., All rights reserved.Book Part Detached Yet Connected: Life and Tension Between the Dodecanese Islands and the Turkish Mainland in the Interwar Period(Taylor and Francis, 2024) Papuççular, H.This chapter shows that the formation of a vague border in the Aegean Sea after the transfer of the Dodecanese to Italy created legal and quotidian problems for the islanders. It reveals that these problems, ranging from property rights to fishing and sponge-diving rights, could not be solved within this period as constant tension reigned in the Aegean. However, the formation of a border did not mean the total disruption of the connection between the islands and the Anatolian mainland. On the contrary, the mobility of the islanders generated a constant challenge to the notion of a border, the constitution of which was apparently not only a political but also a social process. © 2025 selection and editorial matter, Valerie McGuire and Aron Rodrigue.Book Part Digital Society and Togetherness Against Discrimination: Analyzing Reactions in Turkish Tweets on George Floyd Protest(Peter Lang AG, 2021) Eyrek, A.This study aims to examine how people react, interact, and come together against discrimination by using social media even if they are in a spatially different location. George Floyd protests spreading around the world are selected as case study for explaining reaction against discrimination on social media. On May 25, 2020, George Floyd died after being arrested by police officers in Minneapolis, United States. After the footage that displays the fatal arresting of George Floyd by police officers had been circulated on social media, street demonstrations were organized. The reaction of people spread through social media networks around the world. Using social movement theories as a theoretical framework and applying a content analysis, this study focuses on the tweets that are written in Turkish under the hashtags related to George Floyd’s death. The data set involves 12 thousand tweets, between May 28 and June 4 (during the first weeks of protests). The results reveal that social media is an essential part of interaction with people and combination of solidarity against discrimination. © Peter Lang GmbH Internationaler Verlag der Wissenschaften Berlin 2021.Article Citation - WoS: 5Citation - Scopus: 5Effects of myrtus Communis L. Extract and Apocynin on Lens Oxidative Damage and Boron Levels in Rats With a High Fat-Diet(Galenos Publ House, 2021) Yasar, Ruya Kuru; Kuru, Dilruba; Sen, Ali; Sener, Goksel; Ercan, Feriha; Yarat, AysenObjectives: Nutritional obesity causes oxidant damage in the body and cataract formation in the lenses by increasing the formation of free radicals. Myrtus communis leaf extracts (Myr) have antioxidant properties, and apocynin (Apo) is an effective NADPH-oxidase inhibitor. The data on tissue boron levels are quite lacking. The aim of this novel study was to investigate the effects of Myr and Apo treatment on boron levels and oxidative lens damage in rats fed a high-fat diet (HFD). Materials and Methods: Wistar albino male rats were randomly divided into four groups: the control group, HFD group, HFD + Myr group, and HFD + Apo group. Body weight and blood lipids were determined before and after the experiment. After decapitating the rats, the lenses were removed and homogenized. Catalase (CAT) and superoxide dismutase (SOD) activities and boron, malondialdehyde (MDA), and reduced glutathione (GSH) levels in the lens homogenates were determined. Results: The HFD increased serum triglyceride (p<0.05), total cholesterol level (p<0.001), body weight (p<0.001), and lens MDA levels (p<0.01) and decreased lens GSH (p<0.05) and boron level (p<0.01), SOD (p<0.001), and CAT activity (p<0.001). However, Myr and Apo treatment reduced the rats' body weight (p<0.001), serum triglyceride (p<0.05), and total cholesterol level (p<0.001) and increased lens boron (p<0.01; p<0.001), GSH levels (p<0.05; p<0.01), and CAT activity (p<0.001). Conclusion: Both Myr and Apo may be able to reduce oxidative stress in the lenses of obese rats caused by HFD by increasing boron levels.Book Part Evaluation Awareness: A University Example(AHFE International, 2025) Akalp H.G.; Saklangıç U.; Aytaç S.Individuals’ fire safety awareness directly affects individual and institutional safety as well as social safety. Fires are among the serious dangers that can cause loss of life and property in workplaces. Fire safety is one of the basic safety precautions that should be taken in workplaces. Reducing fire risks and increasing employees’ awareness are of great importance in terms of occupational health and safety. Fire safety awareness is a critical issue in terms of preventing occupational accidents and directly affects the effectiveness of safety precautions taken in workplaces. This study aims to evaluate the fire safety awareness level of 163 people working in a higher education institution in Turkey and reached by random sampling method, to analyze the effectiveness of current training programs and precautions and thus to reveal what kind of precautions can be taken in terms of occupational safety. The results revealed that employees have a general awareness of fire safety but they lack knowledge about emergency procedures. Within the scope of the study, it was suggested that training programs within the institution should be increased and fire drills should be carried out regularly in order to increase fire safety awareness. © 2025. Published by AHFE.Book Part Evaluation of Labor Market Issues in Sport and Exercise Environment in Turkey(Taylor and Francis, 2021) Ersöz, G.Conference Object Citation - WoS: 1Citation - Scopus: 4Fpga Based Dco-Ofdm Phy Transceiver for Vlc Systems(Institute of Electrical and Electronics Engineers Inc., 2019) Levent, V.E.; Uysal, M.; Saglam, G.; Ugurdag, H.F.; Fajar Rizqi Annafianto, N.; Aydin, F.; Kebapci, B.Satisfying the demand for high bandwidth and low latency in Visible Light Communication (VLC) systems is a difficult challenge. VLC channels exhibit frequency-selectiveness at peak-speeds. This phenomenon generates a serious inter-symbol interference effect. A physical layer (PHY) design that can carry out physical layer communication tasks to overcome all these strains is required. In this study, an FPGA based PHY design that implements DCO-OFDM algorithm is described for VLC systems. A demo was performed with the developed PHY design using an LED transmitter and a photodetector receiver. © 2019 Chamber of Turkish Electrical Engineers.Article From Global Evidence to Local Action Plan: A Novel Building Decarbonization Maturity Scale and Roadmap for nZEB Office Buildings in Developing Contexts − Case of Türkiye(Elsevier Ltd, 2025) Karanfil, B.Y.; Kayaçetin, N.C.; Tereci, A.; Bıyıklı, N.; Kılınç Gilisıralıoğlu, M.; Karaer, D.To effectively combat climate change, various policies and strategies are being developed to reduce emissions by 2050. The construction sector assumes a pivotal role in achieving decarbonization targets. It is imperative to acknowledge the potential of practices in developing countries, which can provide the critical part of carbon reduction on a global scale. In this context, Nearly Zero Energy Buildings (nZEB) are attracting global attention as a key component of sustainable construction and urban regeneration. Despite high level of energy efficiency and potential to utilize renewable energy, nZEBs have not found widespread application in developing countries. This study benefits from a systematic review of the whole-life decarbonization process of nZEB office buildings. The study evaluated policy frameworks, implementation, and potential emission reduction strategies through energy efficiency measures, material selection, and the integration of renewable energy. In response, the study proposes a structured, context-sensitive decarbonization maturity scale and roadmap to guide policy and practice in developing countries and utilized Türkiye as a case study example. The findings reveal that Türkiye’s current nZEB definition positions it at Level 2 (Emerging) on the decarbonization maturity scale. The country’s high carbon intensity signals the urgency of prioritizing demand reduction and efficiency. Despite enhancements, nZEB offices in Türkiye exhibit high carbon emissions, with operational emissions ranging from 7.5 to 35 kgCO2-eq/m2/year and embodied carbon from 182 to 201 kgCO2-eq/m2. As a result, the maturity scale identifies leverage points offering a mechanism to benchmark progress and accelerate climate action in line with international examples approaching Level 5. © 2025 Elsevier B.V., All rights reserved.Article Fully Synthetic, Nature-Inspired Exosome-Mimetics for Melanoma Therapy(Elsevier B.V., 2026) Arda Ozturk N.Z.; Majchrzak O.B.; Ulivi G.; Kirmizibayrak P.B.; Borchard G.; Patrulea V.; Ozer O.Fully synthetic exosome-mimetics (FSEMs) represent a nature-inspired drug delivery system designed to replicate the key physicochemical and biological properties of natural exosomes, while offering the potential to address limitations in scalability and reproducibility associated with natural exosomes. In this study, we prepared FSEMs at the laboratory scale. We loaded them with (–)-epigallocatechin-3-gallate (EGCG) and microRNA-23a (miR-23a), aiming to co-deliver therapeutic small molecules and nucleic acids for the treatment of melanoma. FSEMs were fabricated using three methods: thin-film hydration, ethanol injection, and microfluidics. They were surface-functionalized with either CD9, a tetraspanin involved in membrane fusion, or TSP-1, an adhesion protein promoting cellular interactions. Through physicochemical characterization via dynamic light scattering, we found that FSEMs were ∼ 100 nm in size, of low polydispersity (∼0.2) and showed a negative zeta potential (∼–55 mV). Both EGCG and miR-23a were efficiently encapsulated. SDS-PAGE analysis confirmed successful protein incorporation and correct positioning. In vitro release studies showed minimal premature leakage, supporting their suitability for cellular uptake-mediated delivery. When tested on melanoma cells (MDA-MB-435) and progenitor human dermal fibroblasts (FE002-SK2), FSEMs selectively killed melanoma cells while sparing fibroblasts. Importantly, EGCG within FSEMs was more effective than the free compound. Compared to conventional DOTAP-based liposomes, FSEMs were more selective and induced less off-target cytotoxicity. This study presents a proof-of-concept for fully synthetic, protein-functionalized FSEMs as dual carriers for both chemical and gene-based agents, offering a safer and potentially more effective alternative to traditional cationic liposomes. These results lay the groundwork for future in vivo validation and translational cancer research. © 2026 The Author(s)Book Part Global Cyberspace Security and Critical Information Infrastructure Protection(Springer International Publishing, 2023) Eldem, T.Book Part Government Responses To the Covid-19 Pandemic: Comparative Health Policies in the Us and Canada(Taylor and Francis, 2023) Erhan, C.; Sıvış, E.In this chapter, we seek to analyse how the United States (US) and Canada handled the COVID-19 pandemic, the resulting consequences on domestic politics, and the overall effect on global geopolitics. The record voter turnout for the 2020 US elections is viewed as an outcome of increased polarisation, politicisation and disinformation, and the general lack of transparency and accountability regarding the COVID-19 crisis under the Trump Administration. On the other hand, although Trump’s isolationist and right-wing policies, in general, pushed Canada into a lonely position in tackling the virus, Canada was able to perform better at handling the virus effectively. Due to robust lockdowns and fiscal stimulus packages and investments in healthcare and COVID-related research, Canada recovered well. Moreover, a comparison of the results of the 2020 US and 2021 Canadian elections indicates that while most Americans distrusted Trump’s pandemic agenda, most Canadians chose to re-elect Prime Minister Justin Trudeau given his successful handling of the virus. © 2024 selection and editorial matter, Erman Akilli, Burak Güneş and Ahmet Gökbel.Book Part Citation - Scopus: 1Green jobs in green transformation story(IGI Global, 2024) Alkan, B.Governments around the world are enacting green recovery and transition programs in collaboration with international agencies. Their coordinated efforts attempt to balance economic growth with environmental preservation, emphasizing that for a sustainable and green future the green transformation is an urgent requirement. The employment component of the green transformation has significant social and economic repercussions. Depending on how prepared countries are for the transition process, skill adaptation and the creation of new job opportunities can provide socioeconomic benefits. "Green jobs" are discussed in the chapter as an important part of the transition strategy to a green economy. The chapter outlines what a "green job" is and is not, presents the connection between employment and skills, and emphasizes the relevance of green jobs in the transition process. © 2024, IGI Global. All rights reserved.Book Part Human-Centered Safety and Ergonomic Design for Women in High-Risk Industrial Occupations: A Systematic Review within Intelligent Systems Context(AHFE International, 2026) Aytac S.; Akalp H.G.; Yamankaradeniz N.; Arlı N.B.Women’s participation in high-risk sectors such as mining, construction, transportation, and healthcare continues to increase, yet industrial safety and ergonomics remain dominated by gender-neutral design assumptions. This systematic review synthesizes evidence on physical, psychosocial, and organizational challenges faced by women in hazardous environments through a human-cantered systems lens. Following PRISMA 2020 guidelines, 24 peer-reviewed studies (2010–2025) from Scopus, Web of Science, and PubMed were analyzed. The literature highlights exposure to musculoskeletal disorders (MSDs), PPE mismatch, postural load, and inequitable access to safety resources. Thematic analysis reveals that ergonomic inequalities intersect with exclusion from safety training and organizational barriers in risk management. Findings underscore the need for interdisciplinary approaches integrating ergonomics, intelligent systems, and gender studies to enable safer and more inclusive workplaces for women in high-risk occupations. © 2026 The Authors.Book Part Hybrid Swara-Vikor Based on Neutrosophic Fuzzy Numbers: an Application(IGI Global, 2024) Büyükselçuk, E.C.In recent years, the burgeoning activity in medical tourism has prompted countries to allocate investments to the healthcare sector, signalling a significant resurgence in national economies. Turkey, like many other nations, has witnessed favourable advancements in this domain. Buoyed by these positive trends and government support, Turkey has expanded its market presence in medical tourism. Concurrently, both public and private hospitals and clinics are endeavouring to capitalize on this growing market share by initiating fresh investments in the sector. This study focuses on assessing the performance of a private healthcare institution operating within Turkey. Leveraging performance criteria established through expert opinions and a thorough literature review, the evaluation of various hospital branches within the healthcare sector was conducted utilizing integrated SWARA-VIKOR methods, employing neutrosophic fuzzy numbers. © 2025 by IGI Global Scientific Publishing. All rights reserved.Editorial Introduction: General Information About Discrimination in Turkey(Peter Lang AG, 2021) Akincilar Köseoğlu, N.; Apak, D.[No abstract available]
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