TR-Dizin İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/9

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Aktivist Reklamlara Yönelik Y ve Z Kuşağının Tutumunun Satın Alma Niyetine Etkisi
(2024) Ugur, Hülya; Tosun, Nurhan Zeynep
Tüketicilerin beklenti ve istekleri doğrultusunda markaların toplumsal konuları gündeme getirerek yeniden canlanması ve eşitlik, adalet gibi temel ve varoluşsal konuları içeren reklam mesajları, yeni bir reklam paradigmasının ortaya çıkmasına zemin hazırlamıştır. Aktivist reklamcılık olarak ifade edilen bu yaklaşım markaların reklam kampanyalarında hedef kitlelerine toplumsal ve sosyal konulara yönelik mesajlar iletmelerini içermektedir. Özellikle toplumsal ve sosyal konularda daha duyarlı olan ve markalardan farklılıklar bekleyen Y ve Z kuşakları için markaların aktivist bir duruş sergilemeleri büyük önem taşımaya başlamıştır. Bu doğrultuda bu çalışma, yeni bir reklamcılık akımına ışık tutan aktivist reklamlara yönelik tutumların satın alma niyeti üzerindeki etkisini değerlendirmeyi amaçlamaktadır. Bu kapsamda çalışmada reklama yönelik tutum oluşumu üzerinde önemli bir etkiye sahip olan (a) reklam değeri, (b) güvenilirlik (c) bilgilendiricilik, (d) aldatıcılık, (e) eğlendiricilik ve (f) rahatsız edicilik tutum değişkenlerinin aktivist reklama yönelik tutum ve satın alma niyeti üzerindeki etkisi de irdelenmiştir. Bu bağlamda çalışmada nicel araştırma yöntemlerinden biri olan anket tekniği kullanılarak 417'si Y kuşağı ve 417'si Z kuşağı olmak üzere 834 birey anket çalışmasıyla değerlendirilmiştir. Y ve Z kuşağı katılımcıları bağlamında aktivist reklamlara yönelik tutumların satın alma niyeti üzerindeki etkisi değerlendirildiğinde, regresyon analizinin bağımlı değişken (satın alma niyeti) ile bağımsız değişken (reklama yönelik tutum) arasındaki etkileşimi anlamlı bir şekilde ortaya konmuştur. Ayrıca reklama yönelik tutum oluşumunda önemli rol oynayan tutum değişkenleri boyutlarının aktivist reklama yönelik tutum ve satın alma niyeti üzerindeki etkisi değerlendirildiğinde, bağımlı değişkenler (tutum, satın alma niyeti) ile bağımsız değişkenler (reklam değeri, bilgilendiricilik, aldatıcılık, eğlendirici ve rahatsız edici, güvenilirlik) arasındaki etkileşimi açıklayan regresyon analizinin de anlamlı sonuçlar verdiği görülmektedir.
Citation - WoS: 0
Citation - Scopus: 0
Decreased Stuttering While Walking: Speech and Fmri Findings
(Galenos Publ House, 2023) Oge-Dasdogen, Ozlem; Ulasoglu-Yildiz, Cigdem; Kurt, Elif; Demiralp, Tamer
[No Abstract Available]
Citation - WoS: 0
Determining the Type 2 Diabetes Risks and Healthy Lifestyle Behaviors of First Year University Students
(2023) Eroglu, Nermın; Eroğlu, Nermin; Temiz, Gamze; Hemşirelik Bölümü
Objective: The present study was planned and carried out as a descriptive and cross-sectional study for determining the Type 2 diabetes risks and healthy lifestyle behaviors of first year university students. Methods: The study was carried with 185 students at a foundation university in Istanbul during the dates of November-December 2019. The data were acquired online via Student Information Form, Type 2 Diabetes Questionnaire (FINDRİSK) and Healthy Lifestyle Behaviors Scale. Results: The mean age of the students in the study was 19.79±2.47 years, 53.5 % (n=99) were male, 29.7 % (n=55 previously graduated from another university, 62.1 % (n=115) were students and it was determined that 50.3 % (n=93) had diabetic relatives. It was observed when the diabetes risk status was examined for all participants that they are in the low risk group due to a FINDRISK total score of <7. Conclusion: The study results emphasize the importance of determining the risk for university students to be diabetic in the next decade, putting forth the individuals with high risk and moving onto the next stage for diagnosis. In addition, it has been determined that the level of knowledge of students may have a positive impact on their healthy lifestyle behaviors.
Citation - WoS: 0
Molecular Characterization of Resistance and Virulence Genes in Enterococcus Faecium Strains Isolated Between 2000-2021; Systematic Review
(Bilimsel Tip Yayinevi, 2022) Kahraman Kılbaş, Elmas Pınar; Kilbas, Imdat; Ciftci, Ihsan Hakki; Tıbbi Hizmetler ve Teknikler Bölümü
Introduction: The spread of Vancomycin-Resistant Enterococci (VRE) is a major threat in healthcare institutions, especially for patients in the risk group. The aim of this study is to reveal the antibiotic resistance genes, virulence genes and other accompanying factors detected in vancomycin resistant Enterococcus faecium strains isolated from various clinical specimens in different parts of Turkiye. Material and Methods: For this purpose, a systematic search was carried out using different electronic databases between January 2000 and September 2021. A total of 17 studies were evaluated within the scope of systematic review. Results: The vanA gene was detected the most between the years 2000-2007, and no statistically significant difference was found according to the years. The prevalence of the vanB gene was highest between 2008 and 2013, and no statistical difference was found according to the years (p> 0.05). The vanA gene was mostly detected in Eastern Anatolia, Black Sea, Mediterranean and Aegean, vanB Central Anatolia and Southeastern Anatolia regions. No reports related to the vanC gene were found. Since all strains were E. faecium in our study, it is an expected finding that the vanC gene region was never reported. The esp and hyl gene between 2014-2021. Conclusion: The prevalence of resistance and virulence genes among bacteria is a matter of great concern, limiting treatment options. In particular, effective measures should be taken to prevent healthcare-associated VRE infections, and each institution should report its own resistance data.
Citation - WoS: 4
Citation - Scopus: 4
Molecular Epidemiology of Carbapenem-Resistant Acinetobacter Baumannii Isolates in Turkiye: Systematic Review
(Kare Publ, 2023) Kahraman Kılbaş, Elmas Pınar; Kilbas, Imdat; Ciftci, Ihsan Hakki; Tıbbi Hizmetler ve Teknikler Bölümü
The World Health Organization has designated carbapenem-resistant Acinetobacter baumannii (CRAB) as a "critical" pathogen on the global priority list of antibiotic-resistant bacteria. This study aims to discuss the molecular epidemiology of CRAB isolates in Turkiye in the last 12 years and the prevalence of gene regions associated with resistance or pathogenesis using a systematic review method. Our study consists of a literature search, determination of eligibility and exclusion criteria, qualitative analysis of studies, data extraction, and statistical analysis. All studies were analyzed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Guidelines. The incidence rates of blaOXA-23, blaOXA-23-like, blaOXA-24/40, blaOXA-24/40-like, blaOXA-51, blaOXA-51-like, blaOXA-58, and blaOXA-58-like genes in CRAB strains were 76.4%, 68.6%, 1.2%, 3.4%, 97.0%, 98.6%, 8.4%, and 17.1%, respectively. It was determined that the prevalence of the blaOXA-23 and blaOXA-58 gene regions showed a statistically significant change over the years. Due to the high prevalence of A. baumannii strains carrying the blaOXA-23 variant, it is necessary to follow its geographical distribution and transposon and plasmid movements. Based on available data, molecular surveillance of CRAB strains should be standardized. In addition, sterilization and disinfection processes applied within the scope of an effective struggle against CRAB strains that can remain live on surfaces for a long time should be reviewed frequently.
Citation - Scopus: 1
Nurse Employment In Some Countries In The World And In Turkey
(Association of Executive Nurses, 2023) Soydaş, K.; Harmancı Seren, A.K.
For a well-functioning health system, employing a sufficient number of appropriately qualified nurses is essential. The quantity and quality of nursing care are affected by the physical conditions of the workplace, support services, information systems, administrative practices, training and experience of nurses, care delivery models, and the number of nurses in the unit. Many criteria have been developed considering these different variables. These criteria are used in line with the health policies of each country. The aim of this review is to offer a framework for the employment policies of nurses in the world and Turkey. © 2023 The Authors.
Citation - WoS: 0
The Use of Probiotics in the Treatment and Prophylaxis of Various Diseases in Turkiye: a Systematic Review
(Bilimsel Tip Yayinevi, 2023) Kahraman Kılbaş, Elmas Pınar; Altindis, Mustafa; Tıbbi Hizmetler ve Teknikler Bölümü
The aim of this study is to analyze the available information on the use of probiotics containing different microorganisms, singly or in combination, in order to investigate the effect of probiotics on the treatment, prophylaxis and microbiota of various diseases. In addition to Pubmed, Google Scholar, SCOPUS, EMBASE, Cochrane Library of Systematic Reviews, CINAHL, AMED, Turkish Medline electronic da- tabases, the gray literature was searched to cover the years 2004-2021. Randomized controlled studies (RCTs) included in the specified selection criteria were brought together. RCTs were evaluated using the Cochrane risk of bias tool. Of the 32 RCTs included in total, only yeast (Saccharomyces spp.) was administered in fourteen, only Lactobacillus spp. in six, Bifidobacterium spp. only in four, and probiotic supplementation containing more than one bacterial strain in six. Only 10/32 of the included studies fully reported the probiotic strain, and 22/32 reported only at the species level. In all nine studies using probiotics for the treatment of diarrhea, probiotics were reported to shorten the duration of diarrhea and length of hospital stay. Four of the five studies reporting the use of probiotics in the treatment of necrotizing enterocolitis reported that probiotics were not effective in reducing the incidence of necrotizing enterocolitis, but could improve nutritional tolerance. In two of the four RCTs investigating the use of probiotics in the treatment of Helicobacter pylori infec- tion, it was stated that the side effects associated with eradication therapy decreased. In both studies conducted for prophylaxis, it was reported that probiotics prevent antibiotic-associated diarrhea. This study shows that probiotics have positive results for the treatment indications and prophylaxis of various diseases. For the sustainability of these health benefits and the safe administration of probiotics, more research is needed that includes strain information and side effect reports.
Citation - WoS: 1
The War Against the Resistance of acinetobacter Baumannii: a Meta-Analysis of Findings in Turkiye
(Erciyes Univ Sch Medicine, 2022) Kahraman Kılbaş, Elmas Pınar; Kilbas, Imdat; Kilbas, Elmas Pinar Kahraman; Tıbbi Hizmetler ve Teknikler Bölümü
Objective: Bacterial resistance to antibiotics continues to be a significant challenge to the global health system. This study was designed to examine changes in the antibiotic resistance of Acinetobacter baumannii (A. baumannii) strains isolated from various clinical samples taken between 2005 and 2020 and to support the development of new antibiotics policies for empirical treatment of multidrug-resistant isolates in Turkiye. Materials and Methods: This meta-analysis included a data search phase, determination of eligibility criteria, qualitative analysis of the studies selected, data extraction, and statistical analyses. All of the data were analyzed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results: According to Clinical and Laboratory Standards Institute and/or European Committee on Antimicrobial Susceptibility Testing standards and a random effects model, the breakpoint estimate of A. baumannii strain resistance in Turkiye for ampicillin-sulbactam, ceftazidime, imipenem, meropenem, gentamicin, amikacin, ciprofloxacin, piperacillin-tazobactam, trimethoprim-sulfamethoxazole, netilmicin, colistin, and tigecycline was 90.7%, 92.1%, 86.8%, 87.3%, 72.6%, 63.7%, 88%, 91.2%, 76.7%, 27.1%, 7.9%, and 18.5%, respectively. Conclusion: The reported rates of A. baumannii resistance from different regions demonstrated heterogeneity. Unfortunately, the use of standard antibiotics is unlikely to provide effective therapy throughout Turkiye. New therapy options and protocols are needed.
Yeşil Kimya Teknikleri ve Moleküler Docking Yöntemleri ile Yeni Florokinolon Hibrit Moleküllerin Sentezi, Dna Giraz, Topoizomeraz Iv İnhibisyonu ve Antibakteriyel Aktivitelerinin Araştırılması
(2021) Durukan, İnci; Kulabaş, Necla; Akdemir, Atilla; Faiz, Özlem; Ayvaz, Aslıhan; Kilic, Ali Osman; Demirbaş, Ahmet
Bu projede öncelikle, literatür verilerinden ve grubumuzun daha önceki çalışmalardan elde ettikleri sonuçlara (yapı-aktivite ilişkileri, SAR) dayanılarak DNA giraz ve topoizomeraz IV inhibisyonu göstermesi öngörülen ve florokinolon-heterohalka hibrit bileşikleri içeren sanal veribankası oluşturulmuştur. Daha sonra bu veribankasından ön çalışmalarımızda geliştirdiğimiz ve valide ettiğimiz sanal tarama yöntemleri ile E. coli veya S. aureas DNA giraz veya DNA topoizomeraz IV enzimlerini inhibe etme potansiyeline sahip olan 75 bileşik sentez için önerilmiştir. Sentezlenen bütün bileşikler enzim inhibisyonu ve antimikrobial aktivite deneylerinde test edilmiştir. Sentezlenen bileşiklerin bazılarının giraz ve topoizomeraz IV inhibisyonu göstermemesine karşılık bilinen antibakteriyel ilaçlar olan norfloksazin, siprofloksazin kadar veya onlara yakın derecede antibakteriyel aktivite göstermesi, bunların florokinolon antibiyotiklerinden farklı bir mekanizma üzerinden etki ettiklerini göstermektedir ki bu durum özellikle ilaç direnci probleminin üstesinden gelme çalışmalarına katkı sağlama potansiyeli göstermektedir. Sentez çalışmalarında geleneksel ısıtma veya karıştırma yöntemlerine ilaveten mikrodalga veya ultrasonik ışınlandırma tekniklerinin de denenmiş ve geleneksel yöntemlere üstünlük sağlayan sonuçların elde edilmiş olması, bu çalışmayı yeşil kimya tekniklerinin geliştirilmesi açısından da değerli kılmaktadır.

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