Kahraman Kılbaş, Elmas Pınar
Loading...
Profile URL
Name Variants
Kilbas, Elmas Pinar Kahraman
Kahraman Kilbas, Elmas Pinar
Kahraman Kilbas, E.P.
Kılbaş, Elmas Pınar Kahraman
Kahraman Kilbas, Elmas Pinar
Kılbaş, E.P.K.
Kahraman Kilbas, Elmas Pinar
Kahraman Kilbas, E.P.
Kılbaş, Elmas Pınar Kahraman
Kahraman Kilbas, Elmas Pinar
Kılbaş, E.P.K.
Job Title
Öğretim Görevlisi
Email Address
elmas.kahraman@fbu.edu.tr
Main Affiliation
Tıbbi Hizmetler ve Teknikler Bölümü
Tıbbi Hizmetler ve Teknikler Bölümü
Tıbbi Hizmetler ve Teknikler Bölümü
Tıbbi Hizmetler ve Teknikler Bölümü
Tıbbi Hizmetler ve Teknikler Bölümü
Tıbbi Hizmetler ve Teknikler Bölümü
Tıbbi Hizmetler ve Teknikler Bölümü
Status
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
Sustainable Development Goals
3
GOOD HEALTH AND WELL-BEING
12
Research Products
6
CLEAN WATER AND SANITATION
1
Research Products
15
LIFE ON LAND
1
Research Products
Scholarly Output
20
Articles
20
Citation Count
11
Supervised Theses
0
20 results
Scholarly Output Search Results
Now showing 1 - 10 of 20
Review Citation - WoS: 1Citation - Scopus: 1A Systematic Review and Meta-Analysis of Molecular Characteristics on Colistin Resistance of acinetobacter Baumannii(Mdpi, 2024) Ciftci, Ihsan Hakki; Kilbas, Elmas Pinar Kahraman; Kilbas, Imdat; Tıbbi Hizmetler ve Teknikler BölümüBackground: This study aimed to determine the molecular epidemiology of colistin-resistant A. baumannii in the last ten years and the frequency of gene regions related to pathogenesis, to compare the methods used to detect genes, and to confirm colistin resistance. Methods: This meta-analysis study was conducted under Preferred Reporting Items for Systematic Reviews and Meta-Analysis Guidelines. In the meta-analysis, research articles published in English and Turkish in electronic databases between January 2012 and November 2023 were examined. International Business Machines (IBM) Statistical Package for the Social Sciences (SPSS) Statistics for Macbook (Version 25.0. Armonk, NY, USA) was used for statistical analysis. The Comprehensive Meta-Analysis (CMA) (Version 3.0. Biostat, NJ, USA) program was used for heterogeneity assessment in the articles included in the meta-analysis. Results: After evaluating the studies according to the elimination criteria, 18 original articles were included. Among colistin-resistant strains, blaOXA-51 positivity was 243 (19.61%), blaOXA-23 was 113 (9.12%), blaOXA-58 was 7 (0.56%), blaOXA-143 was 15 (1.21%), and blaOXA-72 was seen in two (0.16%) strains. The positivity rates of pmrA, pmrB, and pmrC were found to be 22 (1.77%), 26 (2.09%), and 6 (0.48%). The mcr-1 rate was found to be 91 (7.34%), the mcr-2 rate was 78 (6.29%), and the mcr-3 rate was 82 (6.61%). Conclusions: The colistin resistance rate in our study was found to be high. However, only some research articles report and/or investigate more than one resistance gene together. Additionally, it may be challenging to explain colistin resistance solely by expressing resistance genes without discussing accompanying components such as efflux pumps, virulence factors, etc.Article Sakarya İlinde İçme ve Kullanma Sularından İzole Edilen Escherichia Coli Suşlarının Antibiyotik Direnç Durumlarının Belirlenmesi(2024) Naşide,; Kılbaş, Elmas Pınar Kahraman; Çıftcı, Ihsan Hakkı; Tıbbi Hizmetler ve Teknikler BölümüSu sistemlerinde patojen kontaminasyonu giderek artmakta ve bu durum, özellikle çocuklar arasında gastrointestinal enfeksiyonların artmasına yol açmaktadır. Bu çalışmanın amacı, Sakarya il sınırlarında içme ve kullanma sularındaki Escherichia coli kontaminasyon riskini belirlemek ve izole edilen suşların antibiyotik direnç durumlarını incelemektir. Sakarya ilçelerinden 2023-2024 yılları arasında toplanan 450 su numunesinden E. coli izolasyonu, membran filtreleme yöntemi ve kromojenik koliform agar (CCA) kullanılarak yapıldı. Bakterilerin antibiyotik dirençleri disk difüzyon yöntemi ile değerlendirildi. Çalışmada 450 su numunesinin %15,6'sında E. coli tespit edildi. Geyve ilçesinden alınan su numunelerinin %72'sinde E. coli bulunmuş olup, bu oran diğer ilçelere göre istatistiksel olarak anlamlı derecede yüksek bulundu (p<0.05). İzole edilen suşların %25,71'inin bir veya daha fazla antibiyotiğe dirençli olduğu belirledi. E. coli suşları genel olarak karbapenemler ve 3. kuşak sefalosporinlere duyarlıdır, ancak bazı bakteri izolatlarında penisilin ve sefalosporinlere karşı direnç tespit edildi. Tarım ve hayvancılığın yoğun olduğu bölgelerde içme ve kullanma sularında yüksek E. coli kontaminasyonu ve antibiyotik direnci tespit edilmiştir. Bu durum, yanlış ve aşırı antibiyotik kullanımının bir sonucu olarak görülmektedir. İçme sularındaki bu kontaminasyon, halk sağlığı açısından büyük bir risk oluşturmaktadır. İçme ve kullanma sularındaki E. coli varlığı, suyun dezenfeksiyonunda eksiklikler olduğunu ve fekal kontaminasyon riskini işaret etmektedir. Su arıtma tesislerinin ve dezenfeksiyon yöntemlerinin iyileştirilmesi, antibiyotik direncinin önlenmesi ve halkın bilinçlendirilmesi büyük önem taşımaktadır. Bu çalışmanın sonuçları, suyun güvenli ve hijyenik bir şekilde temin edilmesinin gerekliliğini vurgulamaktadır.Review Citation - WoS: 6Citation - Scopus: 7Molecular Epidemiology of Carbapenem-Resistant Acinetobacter Baumannii Isolates in Turkiye: Systematic Review(Kare Publ, 2023) Kilbas, Elmas Pinar Kahraman; Kilbas, Imdat; Ciftci, Ihsan Hakki; Tıbbi Hizmetler ve Teknikler BölümüThe World Health Organization has designated carbapenem-resistant Acinetobacter baumannii (CRAB) as a "critical" pathogen on the global priority list of antibiotic-resistant bacteria. This study aims to discuss the molecular epidemiology of CRAB isolates in Turkiye in the last 12 years and the prevalence of gene regions associated with resistance or pathogenesis using a systematic review method. Our study consists of a literature search, determination of eligibility and exclusion criteria, qualitative analysis of studies, data extraction, and statistical analysis. All studies were analyzed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Guidelines. The incidence rates of blaOXA-23, blaOXA-23-like, blaOXA-24/40, blaOXA-24/40-like, blaOXA-51, blaOXA-51-like, blaOXA-58, and blaOXA-58-like genes in CRAB strains were 76.4%, 68.6%, 1.2%, 3.4%, 97.0%, 98.6%, 8.4%, and 17.1%, respectively. It was determined that the prevalence of the blaOXA-23 and blaOXA-58 gene regions showed a statistically significant change over the years. Due to the high prevalence of A. baumannii strains carrying the blaOXA-23 variant, it is necessary to follow its geographical distribution and transposon and plasmid movements. Based on available data, molecular surveillance of CRAB strains should be standardized. In addition, sterilization and disinfection processes applied within the scope of an effective struggle against CRAB strains that can remain live on surfaces for a long time should be reviewed frequently.Review Citation - WoS: 1Update on the First Year of Covid-19(Galenos Publ House, 2021) Kahraman Kilbas, Elmas Pinar; AltindIS, Mustafa; Yilancioglu, Kaan; TekIn, Ishak Ozel; Buran, Duran; Ozkan, Secil; Ilhan, Mustafa Necmi; Tıbbi Hizmetler ve Teknikler BölümüThe current outbreak of the Coronavirus, severe acute respiratory syndrome Coronavirus-2, which originated in the Wuhan province of the People's Republic of China became a pandemic. Although the clinical findings of the infection vary in adults, the most common symptoms are fever, dry cough, and shortness of breath. The diagnosis of the Coronavirus disease-2019 (COVID-19) is made by clinical symptoms, laboratory tests, and radiological methods. Many drugs such as antivirals, antibiotics, and corticosteroids are used in the treatment of COVID-19. For the successful control of the pandemic, prevention strategies are the key. There is strong consensus that, in addition to wearing masks, hand hygiene, and social distancing, an effective COVID-19 vaccine is probably the most effective approach to sustainably control the pandemic. In this article, current information about the pathogenesis, epidemiology, risk groups, diagnosis, treatment, prevention strategies, and vaccination of the disease in the first year of the COVID-19 pandemic are discussed.Article Acute Serious Hepatitis of Unknown Cause in Children(Galenos Publishing House, 2022) Kılbaş, E.P.K.; Altındiş, M.; Tıbbi Hizmetler ve Teknikler BölümüOn April 5, 2022, an increase in cases of acute hepatitis of unknown etiology was reported in previously healthy children under the age of 10 in the United Kingdom. Since there is no link between these patients, called acute non-HepA-E hepatitis, and viral hepatitis agents (hepatitis A, B, C, D, and E), the possible etiology, and pathogenesis of this emergency is being investigated. One of the alarming features of this epidemic is the high requirement for liver transplantation in a fraction of the cases. In cases other than hepatitis A, B, C, D, and E, a case definition is made by looking at a series of clinical pictures, including serum transaminase levels and age. As of August 26, 2022, 513 cases of acute hepatitis have been reported in Europe and 1,010 globally. Adenovirus was detected in 75% of cases tested in the UK, but data for other countries are still lacking. The role of other etiologic agents is still under investigation. The exact disease pathogenesis has not yet clear. Evidence of human-to-human transmission of the disease remains unclear. Epidemiological studies are critical in clarifying the uncertainties regarding the existence of links between the cases reported to date. Continuing the national and international surveillance activities of the countries in an organized manner is the most basic issue required for the elimination of the epidemic. Copyright © 2022 Tehran University of Medical Sciences.Review Citation - WoS: 1Citation - Scopus: 2Seroprevalence of Torch Viral Agents in Pregnant Women in Turkey: Systematic Review and Meta-Analysis(Mdpi, 2025) Kilbas, Elmas Pinar Kahraman; Ciftci, Ihsan Hakki; Kilbas, Imdat; Toptan, Hande; Tıbbi Hizmetler ve Teknikler BölümüRubella Virus, Cytomegalovirus (CMV), Herpes Simplex Virus-2 (HSV-2), Hepatitis B (HBV) and Hepatitis C virus (HCV) can cause serious fetal disease. The seropositivity rates of these agents vary among countries and geographic regions. This study aimed to analyze the prevalence rates and diagnostic methods used in studies investigating the seroprevalence of viral pathogens in the TORCH group among pregnant women in Turkey between 2005 and 2024. A systematic search was conducted using electronic databases between January 2005 and January 2024. A total of 60 studies meeting the inclusion criteria were included. Data quality control was assessed using the Joanna Briggs Institute guideline prevalence studies checklist. Heterogeneity was measured using the I-squared (I-2) statistic in the Comprehensive Meta Analysis (CMA) program. The average seropositivity rates for Rubella, CMV, HSV-2, HBV and HCV in Turkey were determined as 91.18%, 94.81%, 35.52%, 1.66% and 0.25%, respectively. When the diagnostic methods were examined, it was determined that ELISA and ECLIA methods were used most frequently. The seropositivity of the agents did not show statistically significant differences according to the year periods, geographical regions and age of the patients (p > 0.05). The highest prevalence rates of Rubella and HSV-2 in pregnant women were reported in the Mediterranean region, the highest prevalence rates of CMV and HCV in the Southeastern Anatolia region and the highest seroprevalence of Anti HBs in the Marmara region. The results of this study support the necessity of increasing public awareness in the control of fetal infection caused by TORCH viral agents, prenatal screening, vaccination for Rubella and HBV and compliance with hygiene conditions for agents such as CMV, HSV-2 and HCV. The results of this study highlight the need to increase public awareness on prenatal screening for the control of fetal infection caused by all TORCH viral agents, vaccination for Rubella and HBV and compliance with hygiene conditions for agents such as CMV, HSV-2 and HCV.Review Citation - WoS: 3Citation - Scopus: 3Seroprevalence of coxiella Burnetii in Human and Animal Populations in Tiirkiye: Meta-Analysis(Kafkas Univ, veteriner Fakultesi dergisi, 2023) Kilbas, Imdat; Kahraman Kilbas, Elmas Pinar; Ciftci, Ihsan Hakki; Tıbbi Hizmetler ve Teknikler BölümüThis study aims to reveal Coxiella burnetii by examining the studies reporting Q fever seroprevalence in humans and animals in the last 25 years in Turkiye. In this study, based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), various databases were searched between January 1997 and October. 2022. A literature review was carried out using data analyses performed using the IBM SPSS Version 25.0 statistical package program and Comprehensive Meta-Analysis (CMA) program. Overall prevalence of C. burnetii in humans was 22.78% (95% CI: 16.43%-29.12%), overall prevalence in animals was 13.49% (95% CI: 10.04-16.93%) was detected. The mean prevalence of C. burnetii in sheep was 19.1%+/- 10.88, 10.46 +/- 6.39% in cattle, 15.21 +/- 10.01% in studies including cattle and sheep together, 11.17 +/- 10.74 in cattle, sheep and goats, and 12.4%+/- 1.15% in sheep and goats. As a result of this study, it was determined that the prevalence of Q fever in humans in Turkiye is high in those dealing with animals, women who had a miscarriage, and infertile individuals. Although it is known that this disease is seen in Turkiye, there are not enough case reports in the literature. Detailed studies on Q fever in humans and animals need to be conducted. Further studies are needed to evaluate Q fever risk factors and prevalence data together within the scope of One Health approach.Article Citation - WoS: 3Evaluation of the Relationship Between Dentist Knowledge of the Covid-19 and the Using of the Rubber Dam in Endodontic Treatment(Amber Publication, 2021) Bilgili, Duygu; Kilbas, Elmas Pinar Kahraman; Tıbbi Hizmetler ve Teknikler BölümüPurpose: The aim of this study is to assess the change of the using of rubber dam related to COVID-19 pandemic and knowledge of dentists about this virus. Material and Methods: A questionnaire developed by the researchers in our study was sent to dentists through various channels (university websites, social media) to fill out. A total of 389 participants participated in the study. The questionnaire consists of 3 parts and consists of 31 questions in total. In the first part, there are 8 questions about the demographic characteristics of the participants, 7 in the second part that evaluate the use of rubber dam by the dentists, and in the third part there are 16 questions that measure their knowledge level about COVID-19. Results: In our study, 27.5% of all participants and 56.4% of endodontists reported that the frequency of using rubber dam during endodontic procedures increased during the COVID-19 pandemic. However; it was found that the knowledge levels of all participants and endodontists (when evaluated separately) did not differ according to their education on COVID-19 and the use of rubber dam. (p>0.05). Conclusion: Although the using of the rubber dam has increased with the COVID-19 pandemic, the using of the rubber dam during root canal treatment is still very low, in our study. Although no relationship was found between the knowledge level of COVID-19 and the using of the rubber dam, the factors affecting the using of the rubber dam should be investigated by other studies.Article Twenty-Year Course of Antifungal Resistance in Candida Albicans in Türkiye: A Systematic Review and Meta-Analysis(MDPI, 2025) Kilbas, Imdat; Kahraman Kilbas, Elmas Pinar; Horhat, Florin George; Ciftci, Ihsan Hakki; Tıbbi Hizmetler ve Teknikler BölümüThis study aimed to systematically evaluate the resistance rates of Candida albicans to various antifungals based on studies conducted in Turkiye and published between 2005 and 2025 and to analyze the factors contributing to resistance. A systematic literature search was conducted using various keywords in electronic databases (PubMed, Embase, Web of Science, EBSCO, Scopus, Turk Medline and Google Scholar). A total of 42 studies were included in the meta-analysis according to the determined criteria. The quality of the studies was assessed using the Joanna Briggs Institute checklist, and the analyses were performed using appropriate statistical software. The highest resistance rates for fluconazole, itraconazole, and voriconazole were observed in the Aegean and Marmara regions. In the analyses performed with the random-effects model, heterogeneity was found to be high for itraconazole, fluconazole, posaconazole, voriconazole, and caspofungin, and the strongest explanatory variable of this heterogeneity was the geographical region variable. In our study, we determined that antifungal resistance in C. albicans strains in Turkiye is generally low; however, an increasing trend has been observed over the years, especially in amphotericin B resistance. Although the low resistance rates to major antifungal agents such as fluconazole, voriconazole and echinocandins are promising, regional differences and methodological heterogeneity necessitate the development of treatment strategies based on local data.Article Distribution of Respiratory Infection Viruses in 2019-2020 Season and Determination of Oseltamivir Resistance of Influenza Viruses(2024) Kaya, Tuğba; Terzi, Hüseyin Agah; Toptan, Hande; Kılbaş, Elmas Pınar Kahraman; Bayrakdar, Fatma; Cosgun, Yasemin; Altındiş, Mustafa; Tıbbi Hizmetler ve Teknikler BölümüObjective: This study aimed to determine the seasonal distribution of the factor data of viral agents determined by the multiplex PCR method in routine practice in patients admitted to the hospital with upper respiratory tract infection symptoms and to detect oseltamivir resistance in viruses that are positive for Influenza A (H1N1). Methods: Nasopharyngeal swab and bronchoalveolar lavage samples of 354 patients between the ages of 0-94 who were admitted to the Sakarya University Sakarya Training and Research Hospital with symptoms of upper respiratory tract infection between 12 September 2019 and 19 February 2020 were studied with the multiplex PCR method. Oseltamivir resistance was investigated in 11 samples selected from Influenza A (H1N1) positive samples by Sanger sequence analysis method. Results: One or more respiratory viruses were identified in 233 (66%) of 354 respiratory samples evaluated. Of these, 64 (27.5%) are Influenza A/H1N1, 4 (1.7%) are Influenza A/H3N2, 24 (10.3%) are Influenza B, 64 (27.5) are Respiratory. Syncytial Virus A/B (RSV A/B), 58 (24.9%) Rhinovirus/Enterovirus, 18 (7.7%) Adenovirus, 12 (5.2%) Human Metapneumo Virus (hMPV) ), 10 (4.3%) Bocavirus, 4 (1.7%) Parainfluenza 1, 7 (3%) Parainfluenza 3, 3 (1.3%) Parainfluenza 4, 5 (2.1%) were found to be Coronavirus HKU1 and 13 (5.6%) were found to be Coronavirus NL63. More than one factor was detected simultaneously in 45 of 233 positive samples (19.3%). Oseltamivir resistance was not found in any of the 11 influenza A/H1N1 positive samples. Conclusion: No oseltamivir resistance was observed in any of the Influenza A/H1N1 positive samples evaluated in this study. Periodic analysis of influenza A/H1N1 strains for oseltamivir resistance is necessary to guide empirical treatment.
