WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
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Article Assessment of the Nutritional Status of Syrian Refugee Women in the Lactation Period(Sage Publications Inc, 2026) Isik, Tulay; Garipagaoglu, MuazzezBackground: The Syrian civil war has caused large-scale displacement, with many Syrian refugee women migrating to T & uuml;rkiye. Lactation is a critical period requiring adequate nutrition for maternal and infant health. However, data on the nutritional status of lactating Syrian refugee women are limited. Aim: This study aimed to assess the nutritional status of lactating Syrian refugee women who migrated to T & uuml;rkiye due to the Syrian civil war. Methods: A cross-sectional study was conducted between October 5, 2017, and January 29, 2018, with 102 lactating Syrian refugee women with infants aged 0-6 months attending the Istanbul Al Farah Child and Family Support Center. Participants were selected using convenience sampling. Inclusion criteria were being a Syrian refugee woman in the lactation period, having an infant aged 0-6 months, and volunteering to participate in the study. Women with chronic illnesses or metabolic disorders were excluded. Data were collected through face-to-face interviews with the assistance of a translator, using a structured Turkish questionnaire covering demographic information, anthropometric measurements, and 3-day dietary records. Dietary intake was analyzed with the BEBIS9 program and compared to the T & uuml;rkiye Nutrition Guide recommendations. Although the dietary data were collected in 2017-2018, the analysis was conducted using the most up-to-date national guidelines to reflect current public health priorities. Results: Participants (n = 102) had an average age of 27.9 +/- 5.7 years, BMI of 27.3 +/- 4.6 kg/m(2), and monthly income of 1267 TL. Their daily energy intake was 1593.7 +/- 556.5 kcal/day. A large proportion of participants had inadequate intake of micronutrients, with the highest insufficiency observed for pyridoxine (88.2%), followed by vitamin A (81.4%), vitamin C (76.5%), thiamine (71.5%), riboflavin (63.7%), folic acid (81.4%), vitamin B12 (72.6%), iron (62.8%), and zinc (68.6%). Women with higher BMI in early lactation consumed more fat (p < 0.05). Significant associations were found between micronutrient intake and sociodemographic factors (p < 0.05). However, due to the small sample size and use of convenience sampling, the generalizability of the findings is limited. Future studies with larger and more representative samples are needed to confirm these results. Conclusion: Syrian refugee women in the lactation period showed inadequate intake of energy and essential micronutrients, likely due to poor socioeconomic and living conditions. Interventions such as culturally sensitive nutrition education, postpartum micronutrient supplementation, and improved access to migrant-friendly healthcare services are needed. Additionally, targeted policies and sustainable public health nutrition programs-such as food voucher schemes, fortified food distribution, and maternal support groups-should be developed in collaboration with health institutions and NGOs to improve maternal and infant health outcomes in this vulnerable population.Article The Influence of Leisure Screen Time on Sleep Patterns and Feeding Behaviors in Primary School Children(Routledge Journals, Taylor & Francis Ltd, 2026) Aydoner Bektas, Selen; Bumin, GoncaThe increasing use of screen-based devices in children's daily lives has raised concerns about their effects on health behaviors such as sleep and feeding. This study investigated the relationship between leisure screen time and sleep and feeding problems in primary school children. A cross-sectional survey was conducted with 322 children aged 7-10 years and their parents. Parents completed questionnaires measuring children's daily leisure screen time, sleep patterns, and feeding behaviors. Results showed that weekend leisure screen time (M = 149.4 minutes/day) was higher than weekdays. Significant positive correlations were found between leisure screen time and both total feeding problem scores (weekdays: r = 0.22; weekends: r = 0.25, p < .01) and sleep disturbances (weekdays: r = 0.29; weekends: r = 0.32, p < .01). The most affected areas were selective eating and sleep initiation/maintenance. Regression analysis revealed that weekend leisure screen time significantly predicted feeding problems (beta = 0.22, p = .001) and sleep disturbances (beta = 0.27, p < .001), explaining 8% and 12% of the variance, respectively. The findings indicate the importance of managing children's screen time - particularly on weekends - to support healthier sleep and eating patterns and guide family-based interventions.Article Metformin Attenuates PTZ-Induced Seizures and Cognitive Impairment and Is Associated with Altered NOS/NO Signaling: Combined in Vivo and in Silico Evidence(Taylor & Francis Ltd, 2026) Ciltas, Arzuhan Cetindag; Sahin, Bilal; Hacisuleyman, Levent; Çetindağ Çiltaş, ArzuhanBackground: Epilepsy remains a major neurological disorder with high rates of drug resistance and cognitive decline. Repurposing neuroprotective drugs offers a promising approach. Metformin, a widely used antidiabetic agent, has shown anticonvulsant effects, yet its impact on nitric oxide synthase (NOS) isoforms in distinct brain regions remains unclear. Methods: Adult male Wistar rats were allocated into control, pentylenetetrazole (PTZ), or metformin+PTZ groups. Metformin (200 mg/kg, i.p.) was administered for 7 days before induction of acute PTZ seizures (45 mg/kg, i.p.). Seizure severity and latency were assessed using Racine's scale, and cognition was evaluated by the passive avoidance test (PAT). Nitric oxide (NO) and the expression of its synthesizing enzymes, inducible (iNOS), neuronal (nNOS), and endothelial (eNOS), were quantified in the cortex and hippocampus via enzyme-linked immunosorbent assay (ELISA). In silico analyses included target prediction and molecular docking to assess metformin - NOS interactions. Results: Metformin significantly reduced seizure severity, prolonged latency to the first myoclonic jerk, and prevented PTZ-induced memory impairment (all p < 0.001). These behavioral effects were accompanied by reductions in cortical and hippocampal nNOS and iNOS expression, decreased cortical eNOS levels, and lower NO accumulation. TargetNet predicted NOS isoforms among potential metformin targets, and docking indicated moderate binding affinity (-5.2 to -5.9 kcal/mol). Conclusion: Metformin exerted seizure-suppressing and cognition-preserving effects in an acute PTZ model, associated with reductions in NOS isoform expression and NO levels, suggesting altered NOS/NO signaling and supporting its potential as an adjunctive candidate for mitigating seizure-related neuronal dysfunction.Article The Effect of Sportive Latin American Ballroom Dance on Foot and Ankle Posture(Amer Podiatric Med Assoc, 2025) Kayiskiran, Onurcan; Coskunsu, Dilber Karagozoglu; Isiklar, CagdasBackground: Correct use of the feet, step techniques, and positions constitute significant factors in the success of a dancer. Moreover, the type of dance has crucial effects on the posture of the foot and ankle. Therefore, the primary aim of our study was to determine whether there was a relationship between dancesport, dance experience (years), shoe-wearing time (hours), and shoe heel height (centimeters) in dance athletes performing Sportive Latin American Ballroom (SLAB) dance. Second, we aimed to compare the foot posture of SLAB dancers and nondancers with similar demographic characteristics. Methods: Twenty-six professional SLAB dancers and 26 nondancers who had similar demographic characteristics and did not use high-heeled shoes volunteered to take part in this study. Foot posture (using the Foot Posture Index [FPI]), foot pronation (using the navicular drop test [NDT]), tibiocalcaneal angle, hallux valgus angle (HVA) (using a goniometer), and ankle dorsiflexion range of motion (ROM) (using the weightbearing lunge test) were evaluated. Results: There was a positive moderate correlation between FPI score and shoe-wearing time on the dominant (P = .041; r = 0.40) and nondominant (P = .026; r = 0.43) sides. A positive very good correlation was found between shoe heel height and HVA (P < .001; r = 0.75). A negative good correlation was observed between years of dancing and nondominant ankle dorsiflexion ROM (P = .027; r =-0.43). When dancers and nondancers were compared, a statistically significant difference was found between FPI and NDT scores (P < .001). The FPI and NDT scores, tibiocalcaneal angle, HVA, and ankle dorsiflexion ROM were significantly greater in the dancer group compared with the nondancer group (P < .001) in all measurements of the dominant and nondominant sides. Conclusions: Revealing the relationship between dance experience and shoe-wearing time and the difference between the foot posture and deformities of athletes who perform SLAB dance and those of nondancers constitutes a pivotal endeavor that will increase awareness and knowledge among dancers and clinicians. (J Am Podiatr Med Assoc 115(6), 2025; doi:10.7547/24-030)Article Examination of the Relationship Between Mothers' Self-Confidence and Maternal Attachment in the Postpartum Period(Springer Publishing Co, 2025) Kilic, Melek; Yilmaz, Tulay; Kaya, Husniye Dinc; Gunaydin, Sevil; Dinç Kaya, HüsniyeOBJECTIVE: The relationship between self-confidence and maternal attachment during the postpartum period is critical to both the infant's healthy development and the mother's psychosocial adjustment. This study aimed to evaluate the association between mothers' self-confidence levels and maternal attachment during the postpartum period. METHOD: The study employed a descriptive and correlational design. A purposive sampling method was used in the study, and 147 mothers who were between 1 and 4 months postpartum, over the age of 18 years, able to communicate in Turkish and competent to fill out an online survey were included in the study. The data collection tools included the Descriptive Information Form, the Karitane Parenting Confidence Scale (KPCS), and the Maternal Attachment Inventory (MAI). The collected data were processed and analyzed using the Statistical Package for the Social Sciences for Windows, version 24.0. RESULTS: The participants' mean total KPCS score was 35.95 +/- 4.39, and the mean MAI score was 92.71 +/- 5.34. No statistically significant association was found between maternal attachment and parental confidence levels (p > .05). Additionally, no significant differences were observed between participants' sociodemographic characteristics and their scale scores (p > .05). CONCLUSIONS: The findings suggest that maternal confidence and attachment, although both essential components of postpartum adjustment, function as independent constructs influenced by different psychological and contextual mechanisms. Understanding these dimensions separately may provide insights for developing targeted interventions to support mothers in the early postpartum period.Article Myrtus Communis Ameliorates Ionizing Radiation-Induced Cardiopulmonary Injury in Rats: Trod-Grog Study(Keai Publishing Ltd, 2026) Aytekin, Aynur; Isci, Oguzhan; Ozyilmaz, Nagehan; Karaoglu, Sumeyye Yilmaz; Ertas, Busra; Sen, Ali; Atasoy, Beste Melek; Yılmaz Karaoğlu, SümeyyeObjectives: Ionizing radiation (IR), widely used in diagnostic and therapeutic procedures, can damage vital organs such as the heart and lungs through oxidative stress. This study aims to assess the potential radioprotective effect of Myrtus communis (MC) against cardiopulmonary injury. Methods: Thirty female rats were divided into four groups. Control (C) and IR (R) groups received oral saline. The treatment (R+MC) and pretreatment (R+preMC) groups received MC (100 mg/kg) for 4 days (starting on the day of IR) and 8 days (starting 4 days before IR), respectively. All IR-exposed groups (R, R+MC, R+preMC) received a single 10 Gy whole-body irradiation. Histopathological changes were assessed by hematoxylin-eosin staining, while oxidative stress was evaluated by measuring malondialdehyde (MDA), glutathione (GSH), myeloperoxidase (MPO), nitric oxide (NO), superoxide dismutase (SOD), glutathione S-transferase (GST), and tissue factor activity (TFa) levels. Protein profiles in tissues were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Results: Histopathologically, MC reduced alveolar and cardiomyocyte damage in both R+MC and R+preMC groups. IR increased all oxidative stress markers and decreased antioxidant parameters in heart and lung tissues (p < 0.05-0.001). Both MC treatment and pretreatment reversed these effects, significantly reducing oxidative/inflammatory markers and restoring antioxidant enzyme activities (p < 0.05-0.001). The R+preMC group demonstrated a stronger protective effect than the R+MC group. Conclusion: Our study shows that MC has a radioprotective effect on the cardiopulmonary system by decreasing oxidative damage. MC appears to be a promising natural compound for advanced radioprotection research, and further molecular and clinical studies could clarify its mechanisms and potential applications<bold>.</bold>Article Implementation of the Homeostasis-Enrichment (Hep®) Approach for an Infant at Risk for Autism Spectrum Disorder: A Case Report(Necmettin Erbakan Univ, Fac Medicine-Neu Press, 2025) Balikci, Aymen; Balikci, Ayse Firdevs Aracikul; Demirbag, Izgi Miray; Sirma, Gamze Cagla; Beaudry-Bellefeuille, Isabelle; May-Benson, Teresa A.Background and Clinical Significance: This case report explicates the implementation and outcomes of the Homeostasis-Enrichment-Plasticity (HEP (R)) Approach in a 10-month-old male infant with an increased risk of Autism Spectrum Disorder (ASD) who exhibited challenges in sensory functioning and motor development. Case Presentation: The intervention was carried out utilizing the eleven-step HEP (R) Approach process. The Peabody Developmental Motor Scale-2 (PDMS-2), Test of Sensory Function in Infants (TSFI), Adaptive Behavior Assessment System-3 (ABAS-3), and Goal Attainment Scale (GAS) were used as outcome measures before and after the intervention. A pediatric physical therapist conducted an hour-long intervention weekly for 10 weeks using the HEP (R) Approach implementation guide. Post-intervention, the infant's fine and gross motor skill scores in the PDMS-2 and General Adaptive Composite in the ABAS-3 exhibited significant improvement, as determined by the 95% confidence interval overlap analysis. The TSFI total score also improved categorically. An overall GAS score of +1.6 corresponded to a t-score of 74.12, indicating significant progress towards the individualized intervention goals. Conclusions: The HEP (R) Approach enhanced motor development, sensory functioning, general adaptive skills, and parental goals in a 10-month-old infant at risk for ASD. The results support further examination of the HEP approach's effectiveness in infants at risk for ASD.Article Evaluation of Pulmonary Function Test and Peripheral Muscle Strength in Smoking and Non-Smoking University Students(Georg Thieme Verlag KG, 2025) Tekeoglu Tosun, Anil; Yilmaz, Nergis; Uysal, Ogulcan; Aydin, Buket; Cambel, Ilayda; Karagozoglu Coskunsu, DilberObjective This study was conducted to compare pulmonary function and peripheral muscle strength in smoking and non-smoking university students. Materials and Methods Data were collected from 120 volunteer university students aged between 18 and 25 years, who were divided into two groups regardless of gender after their smoking status had been determined. Data were collected using a sociodemographic form, the Pulmonary Function Test (PFT), and the Five Times Sit-to-Stand and Six-Minute Walk tests to assess peripheral muscle strength. These tests were applied to both smoking and non-smoking groups. Results According to GLI 2012 reference values, female non-smokers exhibited significantly higher FEV1 and FEV1/FVC z-scores compared to female smokers (p<0.001 and p=0.008, respectively), whereas no significant differences were observed among males. No significant differences were found between smokers and non-smokers in peripheral muscle strength tests overall; however, gender-specific analyses revealed significant differences in some tests. Conclusion Significant differences were found in some pulmonary function tests between smoking and non-smoking university students, while no overall difference was observed in peripheral muscle strength. Gender-based subgroup analyses suggested varying effects on muscle strength and pulmonary function. Developing targeted smoking awareness programs for university students is important for public health.Article A Novel Acoustic Source Localization Technique for Edge AI Applications: A Lightweight Framework and Implementation for IoT and Smart Sensing Devices(Istanbul University, 2025) Yarkan, S.This paper presents a novel and computationally efficient three-point signal estimation method for acoustic direction finding, designed specifically for low-cost embedded platforms. The proposed approach offers a lightweight alternative to traditional cross-correlation techniques by minimizing computational complexity while preserving high angular resolution. The method was implemented and tested on an STM32F429 microcontroller using a pair of MAX4466 electret microphones arranged on a fixed baseline. The system architecture leverages bare-metal signal processing routines optimized with Acorn RISC Machine Cortex. Microcontroller Software Interface Standard (ARM CMSIS-DSP) libraries, enabling real-time performance on resource-constrained hardware. Extensive experiments were conducted to evaluate the angular estimation accuracy under varying signal-tonoise ratios and source orientations. Results show that the system maintains sub-degree mean square error for source angles up to 30°, with noticeable performance degradation observed at 40° due to the directional response characteristics of the microphone elements. A comprehensive explanation is provided linking this degradation to reduced microphone sensitivity at wider angles of incidence. The proposed solution is ideal for applications requiring embedded acoustic localization, including smart interfaces, vehicular monitoring, and surveillance systems. In addition, the paper discusses the implications of deploying such systems in artificial intelligence (AI)-enabled and security-critical environments, highlighting emerging threats such as adversarial acoustic interference and spoofing attacks. These challenges underscore the importance of resilient and efficient DF methods that can operate reliably within the constraints of embedded systems. The presented work lays the foundation for future research in secure, scalable, and AI-compatible acoustic sensing platforms. © 2025 Elsevier B.V., All rights reserved.Article Psychometric Properties and Transcultural Adaptation of Turkish Version of the Basel Assessment of Adherence to Immunosuppressive Medication Scale(Baskent Univ, 2025) Koken, Zeliha Ozdemir; Ordin, Yaprak Sarigol; Seren, Arzu Kader HarmanciObjectives: This study aimed to translate BAASIS (Basel Assessment of Adherence to Immunosuppressive Medication Scale) into Turkish and to test the psychometric properties of the translated Turkish version of the instrument. Materials and Methods: In this single-center crosssectional study, we included 100 kidney transplant recipients in a university hospital in a western city of Turkiye. The Translation and Cultural Adaptation Report from Professional Society for Health Economics and Outcomes Research was used for the transcultural adaptation of BAASIS to Turkish. We tested the validity of the BAASIS Turkish version by the level of evidence according to the American Educational Research Association guidelines: content validity, internal structure, and relations to other variables. We calculated item-total correlations of the BAASIS Turkish version to examine internal consistency reliability. Results: The content validity index score of BAASIS was calculated as 1.00, indicating agreement between the experts. Exploratory factor analysis evaluated the internal structure of BAASIS, and the coefficients for inter-item correlations ranged from 0.170 to 0.395. The Immunosuppressive Treatment Adherence Scale and the BAASIS nonadherent scores were significantly correlated (r = 0.673, P < .001). The coefficients for item-total correlation analyses ranged from 0.160 to 0.470. Conclusions: The BAASIS Turkish version has acceptable psychometric properties. The scale can be used in clinical practice and research projects in transplantation to assess immunosuppressive medication adherence.