WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
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Article The Relationship Between Spiritual Well-Being, Resilience, and Adherence Among Patients Receiving Hemodialysis Treatment in Türkiye(Springer, 2026) Bulbul, Elif; Sukut, Ozge; Dikec, GulThis study examined the relationship between spiritual well-being, resilience, and adherence of hemodialysis patients and the factors affecting them. The data were collected from 182 hemodialysis patients receiving treatment in a dialysis center who met the inclusion criteria by purposive sampling method in Istanbul. The data were collected with the patient description questionnaire, which measures patient sociodemographic characteristics and characteristics related to the medical diagnosis, the Spiritual Well-Being Scale, the Brief Resilience Scale, and the End-Stage Renal Failure-Adherence Questionnaire. Gender, educational status, employment status, and mean age of patients were found to be correlated with psychological resilience. Marital status, employment status, cohabitants, and mean age of patients were found to be correlated with spiritual well-being. Gender, number of weekly dialysis sessions, and dialysis competencies were found to be correlated with hemodialysis patients' adherence to their treatment. Hemodialysis patients' adherence was positively correlated with both the faith subscale of spiritual well-being and psychological resilience. According to regression analysis, gender and resilience explained 12.8% of the total variance of adherence. This study determined that resilience is an essential factor in increasing the adherence of hemodialysis patients.Article Citation - WoS: 1Citation - Scopus: 1Dual-Phase Malicious User Detection Scheme for IM-OFDMA Systems Using IQ Imbalance(Wiley, 2025) Alaca, Ozgur; Althunibat, Saud; Riza Ekti, Ali; Yarkan, Serhan; Miller, Scott L.; Qaraqe, Khalid A.Physical-layer security techniques have contributed to the achievement of various security objectives in an efficient and lightweight manner. Thus, these techniques have been widely considered for limited-resource networks such as Internet of Things networks. Among the different security objectives, malicious user detection by exploiting physical-layer parameters has demonstrated efficient performance. In this work, malicious user detection in the recently proposed index modulation-based orthogonal frequency division multiple access (IM-OFDMA) is addressed. The proposed malicious user detection scheme exploits the hardware impairments, especially the in-phase and quadrature imbalance parameters, for both legitimate and malicious users to design a dual-phase efficient detection scheme. The proposed scheme accounts for the special characteristics of IM-OFDMA transmission that are different from other multiple-access techniques. The performance of the proposed scheme was evaluated considering detection probability and false alarm probability performance metrics. Moreover, closed-form expressions of these metrics were derived for both phases and were validated by Monte Carlo simulation results under different configurations of IM-OFDMA systems.Article Citation - WoS: 6Citation - Scopus: 6Psychometrics of Job Stress-Related Presenteeism Scale Among Turkish Nurses(Sage Publications inc, 2023) Beklemis, Nihal; Seren, Arzu K. Harmanci K.; Gilbreath, Brad; Harmanci Seren, Arzu K.Presenteeism occurs when workers are present at work but with diminished work capacity due to illness, stress, or other causes. Recent studies report that nursing is one of the leading professional groups experiencing presenteeism. Although studies of illness-related presenteeism predominate, fewer studies have investigated stress-related presenteeism. Nurses in Turkey are particularly vulnerable to stress-related presenteeism because of the country's low nurse-to-patient ratio. A scale for measuring presenteeism from job stress - the Job-Stress-Related-Presenteeism Scale-has been developed but not validated. This study had two objectives: to adapt the Job-Stress-Related-Presenteeism Scale to Turkish to use in measuring of presenteeism from job stress among nurses; and to assess the scale's validity. We conducted a cross-sectional study to test the content validity, construct validity, reliability, and stability of a Turkish version of the Job-Stress-Related Presenteeism Scale on a sample of 261 nurses. The content validity index of the Job-Stress-Related Presenteeism Scale was .65. Item-total score correlation values varied between .44 and .77. The confirmatory factor analyses confirmed the six-item, one-factor construct. The Cronbach's alpha internal consistency coefficient was .86. Results indicated that our adapted version of the Job-Stress-Related Presenteeism Scale is valid and suitable for use in Turkey.Article Citation - WoS: 4Citation - Scopus: 4An Efficient and Robust 3d Medical Image Classification Approach Based on 3d Cnn, Time-Distributed 2d Cnn-Blstm Models, and Mrmr Feature Selection(Wiley, 2024) Akbacak, Enver; Muzoglu, NedimThe advent of 3D medical imaging has been a turning point in the diagnosis of various diseases, as voxel information from adjacent slices helps radiologists better understand complex anatomical relationships. However, the interpretation of medical images by radiologists with different levels of expertise can vary and is also time-consuming. In the last decades, artificial intelligence-based computer-aided systems have provided fast and more reliable diagnostic insights with great potential for various clinical purposes. This paper proposes a significant deep learning based 3D medical image diagnosis method. The method classifies MedMNIST3D, which consists of six 3D biomedical datasets obtained from CT, MRA, and electron microscopy modalities. The proposed method concatenates 3D image features extracted from three independent networks, a 3D CNN, and two time-distributed ResNet BLSTM structures. The ultimate discriminative features are selected via the minimum redundancy maximum relevance (mRMR) feature selection method. Those features are then classified by a neural network model. Experiments adhere to the rules of the official splits and evaluation metrics of the MedMNIST3D datasets. The results reveal that the proposed approach outperforms similar studies in terms of accuracy and AUC.Article Citation - WoS: 18Citation - Scopus: 21Exercise Improves Testicular Morphology and Oxidative Stress Parameters in Rats With Testicular Damage Induced by a High-Fat Diet(Wiley, 2022) Elmas, Merve Acikel; Ozakpinar, Ozlem Bingol; Kolgazi, Meltem; Sener, Goksel; Arbak, Serap; Ercan, FerihaObesity and male infertility are problems that affect population. Exercise is a nonpharmacological way to reduce the negative health effects of obesity. The purpose of this study was to examine the effects of exercise on hormone levels, blood-testis barrier, and inflammatory and oxidative biomarkers in rats that became obese due to a high-fat diet (HFD). Male rats received a standard diet (STD group) or a HFD (HFD group) for 18 weeks. During the final 6 weeks of the experiment, swimming exercises (1 h/5 days/week) were given to half of these animals (STD + EXC and HFD + EXC groups). Finally, blood and testicular tissues were analysed by biochemical and histological methods. Body weight, leptin, malondialdehyde, interleukin-6, TNF-alpha and myeloperoxidase levels, apoptotic cells and DNA fragmentation were increased, and testis weight, insulin, FSH, LH, testosterone, glutathione and superoxide dysmutase levels, proliferative cells, ZO-1, occludin, and gap junction protein Cx43 immunoreactivity were decreased in the HFD group. All these hormonal, morphological, oxidative and inflammatory biomarkers were enhanced in the HFD + EXC group. It is thought that exercise protected testicular cytotoxicity by regulating hormonal and oxidant/antioxidant balances and testicular function, inhibiting inflammation and apoptosis, as well as preserving blood-testis barrier.Article Citation - WoS: 5Citation - Scopus: 5Paricalcitol Protects Against Hydrogen Peroxide-Induced Injury in Endothelial Cells Through Suppression of Apoptosis(Frontiers Media Sa, 2023) Koksal, Muhammet Murat; Sekerler, Turgut; Cevik, Ozge; Sener, AzizeThe vascular endothelium is one of the main targets of oxidative stress which plays an important role in the pathophysiology of vascular damage. Recent studies show that vitamin D can positively regulate endothelial functions in various chronic diseases and in cases of increased oxidative stress. In our study, we investigated the restorative and protective potentials of paricalcitol which is frequently used in patients with chronic renal failure, a vitamin D analogue, in human umbilical vein endothelial cells (HUVEC) before and after H2O2-induced oxidative stress. Paricalcitol treatment after the oxidative stress induced by H2O2 increased cell viability in endothelial cells depending on the dose that was used. While paricalcitol (500 nM) decreased caspase-3 activity and mitochondrial membrane potential loss, it increased nitric oxide (NO) production and reduced glutathione (GSH) levels. Paricalcitol treatment before oxidative stress increased cell viability. It increased NO production and mitochondrial membrane potential while significantly reducing caspase-3 activity. While paricalcitol caused a significant inhibition of protein disulfide isomerase (PDI) reductase activity in healthy endothelial cells, it did not cause a significant change on the PDI reductase activity under oxidative stress conditions. Present study showed that paricalcitol has restorative and protective effects on endothelial cells against oxidative injury, but these effects occur at high concentrations of paricalcitol.