WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6

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  • Article
    Effects of Left and Bilateral Transcutaneous Auricular Vagus Nerve Stimulation on Pain, Mood, and Autonomic Nervous System in Female Patients With Fibromyalgia: a Randomized Controlled Trial
    (Taylor & Francis Inc, 2025) Akkurt, Mustafa Ferit; Ozden, Ali Veysel; Akkurt, Halil Ekrem; Akkurt, Burcu; Bildik, Celaleddin
    Introduction: Fibromyalgia Syndrome (FMS) is a complex disease characterized by widespread pain, fatigue, emotional disturbances, and autonomic dysfunction. Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) has emerged as a potential noninvasive approach to modulate FMS-related symptoms. Purpose: To compare the effects of left and bilateral taVNS on pain, mood, functionality, and autonomic nervous system (ANS) activity in individuals with FMS. Methods: Forty female individuals with FMS were assigned to either a left (n = 20) or a bilateral (n = 20) taVNS group. Both received 11 sessions of taVNS targeting the tragus and concha regions (30 minutes each, 25 Hz, 300 mu s) over nonconsecutive days, excluding weekends and menstrual periods. Visual Analog Scale (VAS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Fibromyalgia Impact Questionnaire (FIQ) were assessed. ANS activity was evaluated via heart rate variability (HRV). After 11 sessions of taVNS, a 2-week follow-up was performed. Results: No significant differences were observed between groups except for FIQ and BAI on day 28 (p = .002-0.008). Both groups showed significant within-group improvements in VAS (r = 0.87-0.94; p < .001), BDI (r = 0.46-0.71; p < .001), FIQ (r = 0.95-0.99; p < .001), and BAI (r = 0.69-0.94; p < .001) scores. Parasympathetic Nervous System (PNS) (p = .365-0.776) and Sympathetic Nervous System (SNS) (p = .598-0.880) indices, which are the subparameters of HRV, showed no significant between-group differences, with small effect sizes (r < 0.15). Conclusion: Both stimulation protocols effectively reduced pain and improved mood and functionality in fibromyalgia, indicating a safe, noninvasive adjunctive treatment option. Clinicaltrials.gov: (Identifier: NCT06871306).
  • Article
    The Effectiveness of Proprioceptive Neuromuscular Facilitation Techniques Versus Conventional Therapy in Patients With Proximal Humerus Fracture: Randomized Controlled Trial
    (Taylor & Francis Inc, 2025) Kus, Gamze; Alpozgen, Ayse Zengin; Ozdincler, Arzu Razak; Gungor, Feray; Altun, Suleyman; Razak Ozdincler, Arzu; Zengin Alpozgen, Ayse
    Background To date, no study has investigated the effectiveness of proprioceptive neuromuscular facilitation (PNF) techniques for patients with proximal humerus fractures (PHF). Objective To compare the effect of PNF, conventional physicaltherapy (CPT) on shoulder passive and active range of motion (ROM), function, muscle strength, pain, kinesiophobia, quality of life (QoL), and patient satisfaction in patients with PHF. Methods A total of 40 patients with PHF were randomly allocated into two groups of CPT and PNF. Both groups received treatment programs three times a week for 6 weeks. The primary measures were shoulder ROM, function, and muscle strength. The secondary measures were pain, kinesiophobia, QoL, and patient satisfaction. Results Forty patients analyzed at the end of the study. There were no statistically significant group-by-time interactions for function, pain, shoulder ROM (active and passive), or muscle strength (p > .05). However, there were statistically significant group-by-time interactions in role limitations due to physical health subscale of the 36-item Short Form Survey (SF-36) in CPT (p = .046, eta(2)(p) = 0.078). In addition, a significant difference was found in patient satisfaction at 3 weeks in CPT (p = .021) but no difference at 6 weeks between groups (p > .05). Conclusion The PNF techniques demonstrated similar outcomes to the CPT in reducing pain, improving function and shoulder ROM, and enhancing quality of life in patients with PHF in short time. According to our findings, PNF techniques are as effective as CPT and can be proposed as a potential adjunctive treatment for patients with PHF. Clinicaltrialnumber NCT05960435