WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6

Browse

Filters

2020 - 20256

Settings

Publisher: search.filters.publisher.SpringerScopus Q: search.filters.scopusQuartile.Q3

Search Results

Now showing 1 - 6 of 6
  • Article
    Unraveling the Persistent Renal Impact of Intrauterine Growth Restriction and Catch-Up Growth: Integrating Morphological Insights with Metabolomic Profiling
    (Springer, 2025) Esrefoglu, Mukaddes; Koktasoglu, Fatmanur; Bayindir, Nihan; Cimen, Fatma Bedia Karakaya; Kirmizikan, Seda; Hekimoglu, Emine Rumeysa; Selek, Sahabettin
    The study aimed to investigate the long-term effects of IUGR and consequent catch-up growth on metabolic health by using a comprehensive approach that included histopathological, immunohistochemical, biochemical, and metabolomics analyses. Sprague-Dawley pregnant rats either undergo bilateral uterine artery ligation or a sham surgery on the 19th day of gestation. The offspring reached catch-up growth, kidney samples were collected at postnatal weeks 2, 4, and 8 for analysis. IUGR rats exhibited a spectrum of changes including reduced glomeruli number, proliferating cell number, altered oxidative stress markers, various enzymes involved in Krebs cycle, mitochondrial dynamics, and energy metabolism. Examination of the 8-week-old cohort identified a broader spectrum of metabolic alterations, notably in the biosynthesis of phenylalanine, tyrosine, and tryptophan, phenylalanine, tyrosine, glyoxylate, dicarboxylate, pyruvate, alanine, aspartate, and glutamate metabolism, glycolysis/gluconeogenesis and citrate (TCA) cycle. Our metabolomics analysis provides insights into the potential disease susceptibility of individuals born with IUGR, including obesity, diabetes, hypertriglyceridemia, cardiovascular diseases, and mental retardation. These findings underscore the intricate interplay between intrauterine conditions and long-term metabolic health outcomes, highlighting the need for further investigation into preventive and therapeutic strategies to mitigate the risk of metabolic diseases in individuals with a history of IUGR.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Evaluation of the Effect of Sociodemographic Characteristics of Patients With Prostate Cancer on Their Sexual Experiences and Self-Efficacy Sexual Experiences and Self-Efficacy of Individuals With Prostate Cancer
    (Springer, 2023) Eroglu, Nermin; Ozkan, Ilknur
    The study was planned as a descriptive study to evaluate the effects of sociodemographic characteristics of prostate cancer patients on their sexual experiences and self-efficacy. The sample of the study consisted of 69 patients with prostate cancer who were followed up for treatment in the outpatient clinic of an oncology hospital between December 2020 and March 2021 and met the inclusion criteria of the stud. Research data were collected by using the Patient Information Form, Arizona Sexual Experiences Scale (ASEX)-Male, and Sexual Self-Efficacy Scale (SSES). The mean age of prostate cancer patients was 67.1 & PLUSMN; 11.74 years, 95.7% (n = 66) were married, 37.7% (n = 66) were university graduates, and 75.4% (n = 52) were unemployed. Patients' mean scores were 19.29 & PLUSMN; 7.66 on the total Sexual Self-Efficacy Scale and 22.08 & PLUSMN; 4.92 on the total Arizona Sexual Experiences Scale. In the study, it was determined that the sexual experiences and sexual self-efficacy of prostate cancer patients differed according to their education level, employment status, and duration of treatment. In the study, it was determined that patients with prostate cancer experienced sexual dysfunction and had low self-efficacy. In line with these results, our recommendations are for health professionals to evaluate the sexual functions of patients with prostate cancer and their sexual self-efficacy, which is an important determinant of sexual life, during the diagnosis, treatment, and care process. In addition, the sociodemographic characteristics of the patients should be considered when planning interventions that increase sexual self-efficacy in the management of sexual problems.
  • Article
    Citation - Scopus: 1
    Irrational Beliefs and Moral Behaviors: Are Irrational Performance Beliefs Predictor of Prosocial and Antisocial Behaviors in Athletes?
    (Springer, 2024) Urfa, Osman; Asci, F. Hulya
    The aim of this study was to investigate the atemporal mediating role of secondary irrational beliefs in the relationship between primary irrational beliefs and prosocial-antisocial behaviors in athletes. Ninety-two males (Mage=19.83 +/- 2.80) and 32 females (Mage=19.28 +/- 1.44), a total of 124 athletes (Mage=19.69 +/- 2.52) voluntarily participated in this study. Irrational Performance Belief Inventory-2 and Prosocial and Antisocial Behavior Scale were administered, and regression analysis was performed by using bootstrapping via PROCESS macro v4.2. Analysis indicated a significant atemporal direct effect of awfulizing belief on prosocial behaviors toward teammates and opponents. The direct effect of low frustration tolerance belief on prosocial behaviors toward opponents was also significant. Demandingness, awfulizing, and depreciation beliefs had atemporal direct effects on antisocial behaviors toward teammates. There were significant atemporal indirect effects of demandingness belief on prosocial behaviors toward teammates through awfulizing, prosocial behaviors toward opponents through low frustration tolerance, and antisocial behaviors toward teammates through low frustration tolerance and depreciation. In conclusion, there is atemporal mediating role of secondary irrational performance beliefs in the relationship between primary irrational performance beliefs and prosocial-antisocial behaviors.
  • Article
    Citation - WoS: 5
    Citation - Scopus: 6
    Comparison of <i>in Vitro</I> Antifungal Activity Methods Using Extract of Chitinase-Producing <i>aeromonas</I> Sp. Bhc02
    (Springer, 2023) Cadirci, Bilge Hilal; Yilmaz, Gulesme
    Biological control to prevent fungal plant diseases offers an alternative approach to facilitate sustainable agriculture. Since the chitin in fungal cell walls is a target for biocontrol agents, chitinases are one of the important antifungal molecules. In this study, the aim was to investigate a new chitinase isolated from a fluvial soil bacterium and to show the antifungal activity of the characterized chitinase by comparing the three common methods. The bacterium with the highest chitinase activity was identified as Aeromonas sp. by 16 S rRNA sequence analysis. Following the determination of the optimum enzyme production time, the enzyme was partially purified, and the physicochemical parameters of the enzyme were investigated. In the antifungal studies, direct Aeromonas sp. BHC02 cells or partially purified chitinase were used. As a result, in the first method in which the Aeromonas sp. BHC02 cells were spread on the surface of petri dishes, no zone formation was observed around the test fungi spotted on the surface. However, zone formation was observed in the methods in which the antifungal activity was investigated using the partially purified chitinase enzyme. For example, in the second method, the enzyme was spread on the surface of PDA, and zone formation was observed only around Penicillum species among the test fungi spotted on the surface. In the third method, in which the necessary time was given for the formation of mycelium of the test fungi, it was observed that the growth of Fusarium solani, Alternaria alternata and Botrytis cinerea was inhibited by the partially purified chitinase. This study concludes that the results of the antifungal activities depend on the method used and all fungal chitins cannot be degraded with one strain's chitinase. Depending on the variety of chitin, some fungi can be more resistant.
  • Article
    Citation - WoS: 2
    Citation - Scopus: 3
    Solution of the Boundary-Value Problem of Heat Conduction With Periodic Boundary Conditions
    (Springer, 2020) Kanca, F.; Baglan, I.
    We investigate the solution of the inverse problem for a linear two-dimensional parabolic equation with periodic boundary and integral overdetermination conditions. Under certain natural regularity and consistency conditions imposed on the input data, we establish the existence, uniqueness of the solution, and its continuous dependence on the data by using the generalized Fourier method. In addition, an iterative algorithm is constructed for the numerical solution of the problem.
  • Article
    Citation - WoS: 4
    Citation - Scopus: 4
    The Direct and Indirect Effects of Irrational Beliefs on Perceived Performance: The Mediation Role of Emotions and Automatic Thoughts
    (Springer, 2023) Urfa, Osman; Asci, Fevziye Hulya
    The aim of this study was to examine the relationship between irrational beliefs and perceived performance and the atemporal mediator role of emotions and automatic thoughts in this relationship. A cross-sectional study design with a convenient sampling method was used in the study. Participants included 395 athletes from basketball, football, handball, and volleyball and consisted of 267 male (Mage = 20.73, SD = 2.37) and 128 female (Mage = 21.33, SD = 2.17) athletes who voluntarily participated in the study. Data was analyzed via a path analysis and irrational beliefs were shown to negatively predict positive emotions and positive automatic thoughts, but these beliefs positively predicted negative emotions and negative automatic thoughts. The direct effect of irrational beliefs on perceived performance was not significant, but its indirect effect on perceived performance through emotions and automatic thoughts was significant. Irrational beliefs negatively predict perceived performance through emotions and automatic thoughts. It is concluded that emotions and automatic thoughts play a significant role in the relationship between irrational beliefs and perceived performance.