WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
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Article The Current Face of Mosaic Art: Flacking Istanbul Examples(Bursa Uludag University, 2025) Ural, A.G.French artist Ememem is an anonymous artist who started producing his artworks in the city of Lyon in 2016. The unknown street artist brought a contemporary perspective to the art of mosaic by decorating or patching the sidewalks with mosaic art. The term ‘flacking’, which he developed to express the combination of various fields such as upcycling, street art, mosaic art, is becoming increasingly common and attracting the attention of local municipalities. The aim of this study is to discuss the art of flacking, which is a face of mosaic art, which is a very old branch of art, derived from current terms. In terms of scope, examples from Istanbul will be tried to be found and compared with foreign examples. French artist Ememem is an anonymous artist who started producing his artworks in the city of Lyon in 2016. The unknown street artist brought a contemporary perspective to the art of mosaic by decorating or patching the sidewalks with mosaic art. The term ‘flacking’, which he developed to express the combination of various fields such as upcycling, street art, mosaic art, is becoming increasingly common and attracting the attention of local municipalities. The aim of this study is to discuss the art of flacking, which is a face of mosaic art, which is a very old branch of art, derived from current terms. Examples from around the world show how mosaic art can be transformed into impressive and meaningful projects in public spaces. However, it has been seen that modern mosaic trials are still insufficient in our country. It has been determined that for the development of mosaic art, various courses, workshops, contemporary examples to be applied in public spaces and initiatives should be made in order not to lose this valuable art. © (2025), All Rights Reserved.Article Protective Effects of Cuscuta Sp. Against Cardiorenal Injury in Bile Duct-Ligated Rats(Istanbul Univ, 2025) Hatipoglu, Bilge Nur; Ozbeyli, Dilek; Sen, Ali; Cevik, Ozge; Ercan, Feriha; Albayrak, Omercan; Sener, GokselObjective: Bile duct ligation (BDL) obstructs bile flow, resulting in bile and toxic substances buildup that causes liver damage. This study investigated the protective effects of Cuscuta sp. methanol extract (CUS) against cardiorenal injury in bile duct-ligated rats. Materials and Methods: Rats were categorised into four groups: Control (C), CUS, BDL, and BDL+CUS. The C and BDL groups received saline, whereas the other groups received oral 250 mg/kg CUS. After 28 days, blood, kidney, and heart tissue samples were collected for biochemical and histological analyses. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), direct bilirubin (DB), and total bilirubin (TB) levels were analysed to determine liver function, while Transforming growth factor-beta (TGF-beta) and hydroxyproline (HYP) levels were evaluated for fibrosis, and 8-hydroxy-2-deoxyguanosine (8-OHdG) levels alongside Na+/K+-ATPase activity were analysed to assess oxidative stress and membrane injury in the heart and renal tissues. Results: AST, ALT, DB, and TB levels were significantly elevated in the BDL group compared with the C group; however, the levels were distinctly lower in the BDL+CUS group than in the BDL group. Additionally, in both tissues, TGF-beta, HYP, and 8-OHdG levels were higher in the BDL group than in the C group, but decreased in the BDL+CUS group, with Na+/K+-ATPase activity being lower in BDL group compared with the C group and significantly increased in BDL+CUS group. Conclusion: CUS has protective effects against oxidative damage and offers antioxidant and anti-inflammatory benefits against cholestasis-induced tissue injury.Article Citation - WoS: 3Citation - Scopus: 2Morphological and Biochemical Investigation of the Protective Effects of Panax Ginseng on Methotrexate-Induced Testicular Damage(Istanbul Univ, 2023) Karakaya-Cimen, Fatma Bedia; Macit, Caglar; Sivas, Guzin Goksun; Akbay, Tugba Tunali; Sener, Goksel; Ercan, Feriha; Cımen, Fatma Bedia KarakayaObjective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in both experimental and clinical studies. This study aims to examine the healing effect of PxG on testicular damage induced by MTX. Materials and Methods: Sprague Dawley male rats (8-week-olds) were used in the study. A single dose ofMTXdissolved in saline (20 mg/kg) was given to MTX and MTX+PxG groups by intraperitoneal injection. PxG dissolved in saline (100 mg/kg) was given by orogastric gavage once a day for 5 days to the MTX+PxG group. Saline was given to the control and MTX groups orally during the experiments. After decapitation, the testis sampleswere obtained. Seminiferous tubules and basement membranewere evaluated histopathologically. Seminiferous tubule diameter and germinal epithelium thickness were measured. Furthermore, oxidative stress parameters such as malondialdehyde, glutathione, superoxide dismutase, and glutathione-S-transferase were measured. Results: MTX treatment caused seminiferous tubule degeneration with a decrease in Johnsen's score, the seminiferous tubule's diameter, and the germinal epithelium's thickness. Parallel with the histopathological results increased testicular oxidative stress with an increase in malondialdehyde level and a decrease of endogenous anti-oxidant activity with a decrease in glutathione level and glutathione-S-transferase and superoxide dismutase activities. PxG treatment improved these histological and biochemical parameters in MTX-induced testis cytotoxicity. Conclusion: MTX treatment causes testicular damage via the oxidative processes. PxG treatment ameliorates MTX-induced testicular damage by inhibiting oxidative stress.Article Reading Basic Design Principles Through Modern Architectural Structures(Nilay Ozsavas Ulucay, 2023) Yıldırım Coruk, İ.; Coruk, Ipek YildirimBasic design principles are taught within the scope of basic design education in the first-year studios. Basic design education and its content have different dimensions from the education system the student previously received due to its structure and difficulty comprehending because it contains new literature for the student and often has abstract educational content. On the other hand, the students have difficulty perceiving the information acquired in this course and question how they can benefit from it in the following years and professional life. Therefore, the aim of the study is to analyze the basic design principles through modern architectural structures. In the study created by qualitative research method, the data were obtained by analyzing the principles mentioned in the determined examples. These examples were selected among the Bauhaus and later modern buildings by considering the role of the Bauhaus school, where the basic design principles emerged in the spread of modern architecture, and the scope of the study was created. As a result of the study, concrete uses and equivalents of basic design principles were revealed with the determined examples. Thus, data on how students will benefit from basic design principles have been revealed. © 2023, Nilay OZSAVAS ULUCAY. All rights reserved.Article Citation - WoS: 3Psychometrics of Stanford Presenteeism Scale-Short Form in Turkish(Cordus, 2022) Teoman, Ezgi; Seren, Arzu Kader HarmanciAIM: Presenteeism means that employees feel obliged to go to work even if there is a real problem that they cannot work.The main purpose is to to adapt the "Stanford Presenteeism Scale-Short Form" into Turkish on Nurses. METHOD: This is a methodological study. The study sample included the nurses working at the medical and surgical clinics of two public hospitals in 2017 in Istanbul. A total of 290 nurses participated in the study. Language, content, construct validities, total item correlation analysis, Kaiser Meyer Olkin, Bartlett tests, confirmatory and explanatory factor analysis (EFA), stability, and Cronbach's alpha reliability analyses were tested. RESULTS: The content validity index of the scale was.92. Two items that have correlation values below.40 were removed from the Turkish form. Cronbach's alpha internal consistency coefficient was.762. The structure of the four-item and single-factor Turkish form was confirmed. CONCLUSION: Stanford Presenteeism Scale-Short Form is a valid and reliable tool for the nurses in Turkey. It is recommended to be used among nurses in different studies. Hospital and nursing care service managers should deal with "presenteeism," since it is becoming a critical health human resource workforce issue. Health care managers may use this tool to evaluate the presenteeism level of their employees.