WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6

Browse

Search Results

Now showing 1 - 10 of 38
  • Article
    Gender Differences in Pain Coping Strategies, Body Awareness, Pain Beliefs, and Job Satisfaction Among Healthcare Workers With Musculoskeletal Pain: A Comparative Study
    (Wiley, 2026) Akyurek, Gokcen; Bektas, Selen Aydoner; Sirin, Ecenur; Kinikli, Gizem Irem
    Objective: To examine gender differences in pain coping strategies, body awareness, and pain beliefs, and to determine how these psychosocial factors are associated with job satisfaction among healthcare workers suffering from musculoskeletal pain. Methods: This cross-sectional study was conducted in a private hospital (June 2021-January 2022) using convenience sampling. A total of 116 healthcare workers (72 women, 44 men) completed the Pain Coping Questionnaire, Body Awareness Questionnaire, Pain Beliefs Questionnaire, and Job Satisfaction Scale. Mann-Whitney U, Spearman correlation, and multiple linear regression analyses were performed. The study followed Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Results: Women had better pain coping (t = 3.416, p = 0.001), body awareness (t = 3.372, p = 0.001), and pain beliefs (t = 2.637, p = 0.001) total scores than men. Women showed significantly higher pain coping, body awareness, and pain belief scores than men (all p < 0.05). The regression models explained 36.4% of the variance in job satisfaction among men (R-2 = 0.364, p < 0.001) and 6.6% among women (R2 = 0.066, p = 0.029). Conclusion: It is important to consider gender-specific differences in pain coping, body awareness, and pain beliefs when designing interventions aimed at improving job satisfaction among healthcare workers with musculoskeletal pain.
  • Article
    Evaluating Artificial Intelligence–Generated Nursing Care Plans: A Scenario-Based Comparative Study of Accuracy, Completeness, Quality, and Readability
    (Wiley, 2026) Basut, Elif Aylin; Konyar, Mukaddes; Eden, Arzu Baygul; Akyaz, Dilek Yilmaz; Baygul Eden, Arzu; Yilmaz Akyaz, Dilek; Cakir, Gokce Naz; Tufekci, Seyma; Esim, Deniz
    Aim This study aimed to evaluate the ability of three generative artificial intelligence tools (ChatGPT, Gemini and DeepSeek) to generate clinically accurate, comprehensive, and readable nursing care plans aligned with standardised nursing taxonomies (North American Nursing Diagnosis Association International, Nursing Interventions Classification, and Nursing Outcomes Classification). The study further explored variations in tool performance across different nursing specialties.Design A descriptive comparative design was used.Methods Ten expert-validated clinical scenarios representing five nursing specialties (Fundamentals of Nursing, Medical, Surgical, Paediatric and Psychiatric Nursing) were presented to the three artificial intelligence tools. Each tool responded to four standardised prompts based on the latest North American Nursing Diagnosis Association International, Nursing Interventions Classification and Nursing Outcomes Classification taxonomies. Outputs were assessed for quality, accuracy, completeness and readability by expert evaluators using validated scales.Results All tools produced nursing care plans of moderate-to-high quality. DeepSeek demonstrated slightly higher accuracy and completeness compared with Gemini and ChatGPT. Surgical nursing scenarios yielded the highest performance, likely reflecting the more protocolised and pathway-driven nature of perioperative care. However, all outputs were incomplete and written at a college-level readability, limiting accessibility for clinical use.Conclusion Generative artificial intelligence tools can support the production of structured nursing care plans requiring expert review and adaptation, particularly in less standardised clinical domains, but their limitations in completeness and readability indicate they should be regarded only as preliminary drafts requiring expert review and adaptation.Impact The study examined whether generative artificial intelligence can reliably assist in creating nursing care plans. All tools performed moderately well, with DeepSeek showing slight advantages, but outputs were incomplete and difficult to read. Findings are relevant to clinical nurses, educators, healthcare managers and policymakers worldwide who are exploring artificial intelligence in nursing workflows.Reporting Method This study adhered to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.Patient or Public Contribution This study did not include patient or public involvement in its design, conduct or reporting.
  • Article
    Nurses on the Frontline of Disaster: A Qualitative Metasynthesis of Post-Earthquake Care Experiences
    (Wiley, 2026) Kolac, Nurcan; Taylan, Secil; Eroglu, Nermin
    Background Earthquakes generate urgent and complex care needs, positioning nurses as key responders. Exploring their post-earthquake care experiences is vital for strengthening disaster preparedness and nursing practice.Aim This study aimed to synthesise qualitative evidence on nurses' experiences of providing care in the aftermath of earthquakes.Study Design This research was conducted through a systematic review and meta-synthesis of qualitative studies. The data were analysed using thematic analysis. The qualitative systematic review was conducted using Sandelowski and Barroso's four-step meta-synthesis methodology. This metasynthesis study, conducted in accordance with the PRISMA statement, is registered in PROSPERO. The following electronic databases and platforms were used for the literature review: MEDLINE, Academic Search Ultimate, CINAHL Complete, Complementary Index, Supplemental Index, Directory of Open Access Journals and WOS.Findings Based on 27 included studies, the research identified four main themes and 13 sub-themes related to nurses' post-earthquake care experiences. These themes were: (1) early post-earthquake nursing challenges, (2) conflict experiences, (3) valued experiences and methods of coping with challenges and (4) impact of rescue experiences.Conclusions This research highlighted nurses' post-earthquake care experiences, emphasising how they overcame challenges, redefined their profession and emerged stronger. It also identified the limitations and facilitators within the post-earthquake care environment, providing valuable insights for enhancing care settings during future earthquakes.Relevance to Clinical Practice This study identified limitations and facilitators in the post-earthquake care environment of clinical settings, providing valuable insights to improve care environments during future earthquakes.
  • Article
    Verification Trials Can Create the Illusion of VO2max in Addition to Contributing to Its Confirmation
    (Wiley, 2026) Cabuk, Refik; Alp, Egemen; Murias, Juan Manuel; Karsten, Bettina
    This study examined whether constant-workload verification trials performed at intensities below, at, and above the ramp-incremental peak power output (PPO) contribute to confirming maximal oxygen uptake (VO2max). Fifteen trained to well-trained male cyclists (VO2max: 63.6 +/- 5.6 mL & centerdot;kg(-1)& centerdot;min(-1)) completed maximal ramp testing followed by seven randomized verification trials (80%-110% PPO at 5% intervals) on separate days. Differences in VO2 responses were analyzed using linear mixed-effects models. Effect size was calculated using Hedges' g. The peak VO2 attained during the verification trials was expressed relative to the ramp-derived VO2max and classified as lower (< 95%), within normal variability (95%-105%), or higher (> 105%). The peak VO2 values at 80%, 105%, and 110% PPO were significantly lower than ramp-derived VO2max (p < 0.05), whereas no significant differences were observed at 85%, 90%, and 95% PPO. Effect sizes were small at 85%-95% PPO (Hedges' g = 0.29-0.32), medium at 100%-105% PPO (Hedges' g = 0.63-0.66), and large at 80% and 110% PPO (Hedges' g = 1.21-1.34). Of 105 verification trials, 81 were within +/- 5% of ramp VO2max, 22 were lower (mainly at 80% and 110% PPO), and two exceeded ramp VO2max (at 85% and 95% PPO). Although verification trials did not meaningfully contribute to the verification of VO2max, trials performed at 85%-95% PPO provided the best chances of confirming VO2max in trained individuals. Interpretation of verification trials relative to ramp-derived PPO is protocol dependent, which may limit generalizability across different ramp designs.
  • Article
    Early Detection of Lower Adherence to Long-Term E-Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis
    (Wiley, 2026) Dramburg, S.; Hernandez Toro, C. J.; Grittner, U.; Tripodi, S.; Arasi, S.; Acar Sahin, A.; Matricardi, P. M.
    Background: Digital symptom monitoring via e-Diary apps can support the diagnosis and management of chronic diseases with trigger-induced exacerbations such as pollen allergies. Attrition is a major challenge for continuous e-Diary usage with an unsupervised approach. Objective: To investigate adherence to e-Diary reporting, its early determinants and predictors in a blended care setting among pollen allergic patients with heterogeneous cultural backgrounds. Methods: The @IT.2020 observational multicenter study recruited patients with diagnosed seasonal allergic rhinitis from seven Southern European/Mediterranean countries. Baseline characteristics were investigated through questionnaires, skin prick tests and serum specific IgE measurements. The study doctors asked patients to record their allergy symptoms via e-Diary (AllergyMonitor, TPS) daily during the clinically relevant season of pollination and increased mould concentrations. Results: Among 815 patients (467 adults, 348 children), the average prescribed e-Diary recording period was 106 (SD 47.1) days, with an average completion rate of 75.2% (SD 21.2%). Children (>= 10 years) filled 73.8% (95% CI 68.1-79.4) of prescribed days without parental support. We identified a stable 'higher' and a more variable 'lower' adherence cluster. Adherence was weakly associated with disease severity, but not with age, gender, country, education or digital literacy. Short-term (first 3 weeks) adherence was strongly associated with long-term adherence (partial R-2 = 0.387, p < 0.001), with 87.6% of lower adherent patients remaining poorly adherent beyond 3 weeks. Conclusion: In a blended care setting, adherence to e-Diary compilation among pollen allergic patients is high, irrespective of age and cultural background. Early identification of lower adherence is possible and might inform early interventions to improve patient adherence.
  • Article
    Investigating the Personal and Professional Variables That Predict Discrimination Attitudes Among Nurses and Physicians
    (Wiley, 2025) Tekin, Suat; Seren, Arzu Kader Harmanci; Harmanci Seren, Arzu Kader
    Introduction: Healthcare professionals are expected to provide holistic care to their patients without discrimination based on factors such as religion, language, age, gender, and race. Design: It is a cross-sectional descriptive study. Aim: The study aimed to examine the discriminatory attitudes of nurses and physicians working in hospitals in Sanliurfa and to define whether the personal and professional variables predict discriminatory attitudes among them. Methods: The STROBE reporting method, which is one of the EQUATOR guidelines, was followed. Data were collected from a total of 376 physicians and nurses through online platforms between March and June 2020 via the information form and the Discrimination Attitude Scale. Results: The discriminatory attitudes of the nurses and physicians participating in the study were above average. The total discriminatory attitudes scores of the participants varied according to sex, income levels, profession, hospital experience, and unit (p < 0.05). In addition, sex, profession and unit variables predicted the total discriminatory attitudes of nurses and physicians (p < 0.05). Conclusion: Although nurses' and physicians' discriminatory attitudes scores were generally higher, the highest mean score was in the subscale "discrimination against other nationalities." Sex, profession, and unit variables predicted the total discriminatory attitudes of nurses and physicians. Further quantitative and qualitative research is needed to understand the reasons for the highest discriminatory attitudes towards other nationalities among healthcare professionals, to overcome this issue. Clinical Relevance: Nursing or healthcare managers, as well as policymakers, may consider the predictive variables when staffing and training nurses and physicians working in similar regions and conditions.
  • Article
    Ludwig's Angina in a 6-Year Child: Case Report
    (Wiley, 2025) Akbari, Negarin; Razavi, Ali; Sabzi, Zahra; Parhiz, Jabbar
    Ludwig's angina is a rare but potentially fatal cellulitis that affects the submandibular, sublingual, and submental spaces, typically triggered by dental infections. This case report details a severe presentation of Ludwig's angina in a 6-year-old girl who presented with submandibular swelling, fever, voice alterations, and respiratory distress. Diagnosis was based on clinical evaluation, supported by CT imaging, revealing significant airway narrowing and lymphadenopathy. The patient was promptly intubated to secure the airway, followed by emergency surgical drainage and intravenous antibiotics. Postoperative care included sedation, ongoing monitoring in the PICU, and close follow-up by multiple specialties. After a 10-day hospitalization, the patient showed significant recovery with no complications. The case underscores the importance of early diagnosis and intervention in preventing severe complications such as airway obstruction, sepsis, and mediastinal spread. It highlights the critical role of interdisciplinary collaboration, including pediatric infectious disease specialists, surgeons, and anesthesiologists, in managing this life-threatening condition effectively.
  • Article
    Citation - WoS: 2
    Citation - Scopus: 3
    Biological Activities of Etodolac-Based Hydrazone, Thiazolidinone and Triazole Derivatives on Breast Cancer Cell Lines MCF-7 and MDA-MB
    (Wiley, 2025) Sevinc, Sevgi Kocyigit; Cikla-Suzgun, Pelin; Tiber, Pinar Mega; Kucukguzel, S. Guniz; Orun, Oya; Güniz Küçükgüzel, Ş.
    In this study, several etodolac-based hydrazone, thiazolidinone, and triazole derivatives that we synthesized and characterized in our earlier research were tested against the hormone-responsive breast cell line MCF-7 and the triple-negative MDA-MB-231, as well as the murine origin fibroblast cell line L-929, at varying doses for their effects on cell viability and toxicity and for their inhibitory activity on cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) formation. Cell viability and apoptosis tests were utilized to assess the anti-cancer potential of etodolac and its derivatives after the cells were exposed to varied concentrations of synthesized compounds for three different time periods. ELISA and Western blot methods were used to detect protein levels. All synthesized compounds demonstrated higher anti-cancer activity at significantly lower doses compared to etodolac (half-maximal inhibitory concentration [IC50] of 0-50 mu M range in derivatives versus 0.5-1 mM range in etodolac). Except for SGK 242, which had a major toxic effect on all cells, the chemicals SGK 206 and SGK 217 had a twice-less impact on control murine L-929 fibroblasts. Similar to proliferation, low concentrations of SGK 206 and SGK 217 (25-50 mu M) significantly induced apoptosis in breast cancer cells but not in normal cells. Additionally, they inhibited COX-2 protein expression at 50 mu M, and SGK 206 inhibited PGE2 release more effectively than etodolac in cancer cells. The results of this study suggest that, in comparison to a healthy control group, the thiazolidinone derivative SGK 206 and the thiazolidinone derivative SGK 217 are more effective than etodolac when it comes to the breast cancer cell lines MCF-7 and MDA-MB-231. SGK 206 exhibits a low IC50 value, a distinct dose-response relationship, and strong apoptotic effects, particularly on MDA-MB-231 cells.
  • Article
    The Effect of Compulsory Citizenship Behaviors on Subjective Vitality Among Nurses
    (Wiley, 2025) Elibol, Esengul; Yildiz, Bora; Seren, Arzu Kader Harmanci
    Aim The study aims to assess the extent of compulsory citizenship behaviors (CCBs) and their impact on the nurses' subjective vitality based on self-determination theory. Background CCBs are harmful to both nurses and organizations. These behaviors mean employees are expected to perform additional tasks outside their job descriptions. Although CCBs are highlighted within the recent nursing literature, empirical evidence of their effects is lacking. Methods This is descriptive cross-sectional research. The study included 244 staff nurses using a convenience sampling method who worked in two hospitals in Istanbul. Data were collected via a survey consisting of a personal information form, the compulsory citizenship scale, and the subjective vitality scale. STROBE guidelines were followed when reporting the study. Descriptive statistical analyses, independent samples t-test, one-way ANOVA test, Pearson's correlation, and hierarchical simple linear regression analyses were used. Results The participants' mean scores for compulsory citizenship and subjective vitality were 3.34 out of 5 (SD = 1.05) and 4.15 out of 7 (SD = 1.36), respectively. Nurses' compulsory citizenship scores significantly differed according to their education level, income, and sector. Their subjective vitality scores statistically differed according to their income levels. Regression analysis revealed that CCBs were significant negative predictors of subjective vitality (beta = -0.22, p < 0.01). Conclusion By examining the CCBs and subjective vitality relationship, the current study extended the existing knowledge by drawing attention to the destructive and harmful effects of CCBs on positive psychological sources of nurses' subjective vitality. CCBs negatively predicted subjective vitality. Clinical Relevance Organizational factors such as CCBs, which leads to a lack of autonomy, affect nurses' well-being, thus affecting care quality and patient safety. As the International Council of Nurses mentioned, "Nurses cope with many physical, mental, emotional, and ethical challenges. It is essential that we address these challenges in a way that supports their overall health". In this regard, managers and policymakers in hospitals should develop preventive cautions for CCBs. However, in-service training activities should be carried out to increase awareness about the harmful effects of CCBs on nurses' psychological well-being.
  • Article
    Citation - WoS: 4
    Citation - Scopus: 4
    Collagen Peptides and Saccharomyces Boulardii Cncm I-745 Attenuate Acetic Acid-Induced Colitis in Rats by Modulating Inflammation and Barrier Permeability
    (Wiley, 2025) Altinok, Oyku; Bas, Murat; Dolanbay, Elif Gelenli; Kolgazi, Meltem; Mert, Tugay; Uslu, Unal; Gelenli Dolanbay, Elif
    Ulcerative colitis (UC) is an inflammatory bowel disease characterized by recurrent episodes of inflammation and tissue damage, with limited treatment options. This study aimed to investigate the effects of collagen peptides and Saccharomyces boulardii on acetic acid (AA)-induced colitis. Thirty-six male Sprague-Dawley rats were randomly divided into the following four groups: normal control (NC), colitis control (CC), collagen peptide (CP; 0.6 g/kg/day), and S. boulardii (SB; 250 mg/day). Colitis was induced by an intrarectal administration of AA in all groups except NC, and treatments were administered daily for 7 days. The therapeutic effects were evaluated by assessing the disease activity index (DAI), colon mass index, macroscopic and microscopic tissue damage, histopathological changes, zonula occludens (ZO)-1 protein expression, and myeloperoxidase (MPO) activity. The results showed that CP and SB treatments substantially alleviated DAI scores (p < 0.05) and reduced the colon mass index. Colon macroscopic and microscopic damages improved compared to the CC group (p < 0.01). Histologically, both treatments reduced inflammatory cell infiltration, crypt damage, and ulceration, with CP showing a slightly more pronounced effect. Immunohistochemical analysis revealed significant restoration of ZO-1 protein expression in the treated groups, indicating improvement in intestinal barrier integrity (p < 0.01). Furthermore, MPO activity was reduced in both CP and SB groups, significantly in the SB group (p < 0.01). These findings are consistent with previous studies that highlight the anti-inflammatory and barrier-enhancing effects of collagen peptides and probiotics in UC models.