WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
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Article Evaluation of Barriers Toward Data-Driven Supply Chain Sustainability Via Single-Valued Pythagorean Piprecia(Amer Inst Mathematical Sciences-AIMS, 2026) Turan, Hakan; Buyukselcuk, Elif CalogluSustainable supply chain management (SSCM) is a holistic approach that encompasses economic, social, and environmental dimensions, enabling firms to enhance their long-term competitiveness by meeting legal requirements and strengthening brand equity. The effective implementation of this approach necessitates a strong emphasis on data-driven decision-making. Accordingly, we aimed to identify the key barriers hindering the implementation of data-driven sustainable supply chain practices and to explore potential strategies to overcome these challenges. In the initial phase of the study, a comprehensive literature review was conducted to identify the major barriers to implementing data-driven sustainable supply chains. Subsequently, the relative importance of these barriers was assessed with input from top and mid-level managers working in manufacturing sector enterprises. The identified barriers were then prioritized using the Pivot Pairwise Relative Criteria Importance Assessment (PIPRECIA) method based on Pythagorean fuzzy numbers. Finally, solution proposals were developed to address the most critical barriers. The study revealed that organizational barriers constitute the most prominent category, representing 29.86% of the total identified obstacles. Closely following are technical barriers, which account for 26.41% and reflect the difficulties associated with implementing and integrating digital technologies. Internal and external environmental barriers are similarly substantial, comprising 25.87% of the total. In comparison, economic barriers make up the smallest share, with a relative weight of 17.86%. The number of researchers analyzing the importance weights of barriers in the context of SSCM 4.0 remains limited. The utilization of a more contemporary and robust method compared to previously applied techniques for determining these weights enhances the originality of this study.Article Assessment of the Nutritional Status of Syrian Refugee Women in the Lactation Period(Sage Publications Inc, 2026) Isik, Tulay; Garipagaoglu, MuazzezBackground: The Syrian civil war has caused large-scale displacement, with many Syrian refugee women migrating to T & uuml;rkiye. Lactation is a critical period requiring adequate nutrition for maternal and infant health. However, data on the nutritional status of lactating Syrian refugee women are limited. Aim: This study aimed to assess the nutritional status of lactating Syrian refugee women who migrated to T & uuml;rkiye due to the Syrian civil war. Methods: A cross-sectional study was conducted between October 5, 2017, and January 29, 2018, with 102 lactating Syrian refugee women with infants aged 0-6 months attending the Istanbul Al Farah Child and Family Support Center. Participants were selected using convenience sampling. Inclusion criteria were being a Syrian refugee woman in the lactation period, having an infant aged 0-6 months, and volunteering to participate in the study. Women with chronic illnesses or metabolic disorders were excluded. Data were collected through face-to-face interviews with the assistance of a translator, using a structured Turkish questionnaire covering demographic information, anthropometric measurements, and 3-day dietary records. Dietary intake was analyzed with the BEBIS9 program and compared to the T & uuml;rkiye Nutrition Guide recommendations. Although the dietary data were collected in 2017-2018, the analysis was conducted using the most up-to-date national guidelines to reflect current public health priorities. Results: Participants (n = 102) had an average age of 27.9 +/- 5.7 years, BMI of 27.3 +/- 4.6 kg/m(2), and monthly income of 1267 TL. Their daily energy intake was 1593.7 +/- 556.5 kcal/day. A large proportion of participants had inadequate intake of micronutrients, with the highest insufficiency observed for pyridoxine (88.2%), followed by vitamin A (81.4%), vitamin C (76.5%), thiamine (71.5%), riboflavin (63.7%), folic acid (81.4%), vitamin B12 (72.6%), iron (62.8%), and zinc (68.6%). Women with higher BMI in early lactation consumed more fat (p < 0.05). Significant associations were found between micronutrient intake and sociodemographic factors (p < 0.05). However, due to the small sample size and use of convenience sampling, the generalizability of the findings is limited. Future studies with larger and more representative samples are needed to confirm these results. Conclusion: Syrian refugee women in the lactation period showed inadequate intake of energy and essential micronutrients, likely due to poor socioeconomic and living conditions. Interventions such as culturally sensitive nutrition education, postpartum micronutrient supplementation, and improved access to migrant-friendly healthcare services are needed. Additionally, targeted policies and sustainable public health nutrition programs-such as food voucher schemes, fortified food distribution, and maternal support groups-should be developed in collaboration with health institutions and NGOs to improve maternal and infant health outcomes in this vulnerable population.Article New Age Negotiations of Power in Türkiye: A Representation of Diverse Profiles(Univ Pennsylvania Press, 2026) Aytimur, Hilal; Guney, H. SerhatNew Age spirituality intersects with power relations in complex ways. This exploratory study investigates how practitioners in T & uuml;rkiye navigate these intersections. Employing a Bourdieusian framework and utilizing survey data analyzed through cluster analysis, we ity and their interactions with its media and discourses. This analysis reveals distinct approaches to power relations within both the New Age field and the broader socio- political context. Our findings identify three distinct groups: vigilant adopters, negotiated readers, and devoted practitioners. This paper argues that these diverse engagements demonstrate that New Age spirituality in T & uuml;rkiye functions not as a unified challenge to or acceptance of power relations, but as a complex field needs, and social positioning, often resulting in nuanced or even contradictory stances towards societal structures.Article 1,2,4-Triazole Conjugates as HEGFR Inhibitors: Synthesis, Anticancer Evaluation, and in Silico Studies(Wiley-V C H Verlag GmbH, 2026) Bulbul, Bahadir; Kulabas, Necla; Gurboga, Merve; Ozakpinar, Ozlem Bingol; Cakmak, Ummuhan; Tuncay, Fulya Oz; Kucukguzel, IlkayA series of novel 1,2,4-triazole-acetamide derivatives was synthesized and evaluated for anticancer and hEGFR inhibitory activity. The compounds were obtained via multistep synthesis and characterized by spectroscopic methods. Cytotoxicity was tested against PC-3, MCF-7, A549, and K562 cell lines. Compounds <bold>18</bold>, <bold>19</bold>, and especially <bold>24</bold> showed notable antiproliferative effects, with compound <bold>24</bold> exhibiting higher selectivity and potency than gefitinib. It also induced apoptosis and inhibited migration in A549 and PC-3 cells, while selectively promoting invasion in PC-3, suggesting EMT-related behavior. In vitro kinase assays revealed compound <bold>20</bold> as the most potent hEGFR inhibitor (IC50 = 43.8 +/- 1.3 nM). Molecular docking and 200 ns molecular dynamics simulations confirmed its stable interaction with EGFR, particularly involving Cys797. These findings highlight compounds <bold>20</bold> and <bold>24</bold> as promising candidates for further development as EGFR-targeted anticancer agents.Article In Vivo Antioxidant and Anti-Inflammatory Effects of Myrtus Communis Against Ionizing Radiation-Induced Gastrointestinal Injury: Trod-Grog Study(Kare Publishing, 2025) Kilic, Melisa Bagci; Varan, Melike Pekyurek; Atasoy, Ozum; Ozyilmaz, Nagehan; Pazarbasi, Seren Ede; Ertas, Busra; Atasoy, Beste Melek; Ercan, FerihaOBJECTIVE: This study aimed to investigate the in vivo radioprotective effects of Myrtus communis (MC) on the gastrointestinal system. METHODS: A total of 30 female rats were divided into four groups: i) Control; ii) irradiation (IR) only; iii) MC-pretreated; and iv) MC-treated. The rats received oral MC extract (100 mg/kg/day) for 4 days before exposure to 10 Gy IR or continued until sacrifice. On the fourth day of IR exposure, the rats were sacrificed, and histopathological and biochemical analyses were performed on the ileum, pancreas, and liver tissues. RESULTS: Malondialdehyde and myeloperoxidase levels decreased in both MC-treated groups, while glutathione levels and Na+-K+-ATPase activity increased (p<0.01), with significant histopathological improvements compared to the IR-only group. CONCLUSION: The results of this study demonstrate that MC significantly decreases ionizing radiation-induced oxidative and inflammatory damage in the gastrointestinal systems of rats. Therefore, it may be regarded as a new candidate with radioprotective potential for future clinical application.Article The Influence of Leisure Screen Time on Sleep Patterns and Feeding Behaviors in Primary School Children(Routledge Journals, Taylor & Francis Ltd, 2026) Aydoner Bektas, Selen; Bumin, GoncaThe increasing use of screen-based devices in children's daily lives has raised concerns about their effects on health behaviors such as sleep and feeding. This study investigated the relationship between leisure screen time and sleep and feeding problems in primary school children. A cross-sectional survey was conducted with 322 children aged 7-10 years and their parents. Parents completed questionnaires measuring children's daily leisure screen time, sleep patterns, and feeding behaviors. Results showed that weekend leisure screen time (M = 149.4 minutes/day) was higher than weekdays. Significant positive correlations were found between leisure screen time and both total feeding problem scores (weekdays: r = 0.22; weekends: r = 0.25, p < .01) and sleep disturbances (weekdays: r = 0.29; weekends: r = 0.32, p < .01). The most affected areas were selective eating and sleep initiation/maintenance. Regression analysis revealed that weekend leisure screen time significantly predicted feeding problems (beta = 0.22, p = .001) and sleep disturbances (beta = 0.27, p < .001), explaining 8% and 12% of the variance, respectively. The findings indicate the importance of managing children's screen time - particularly on weekends - to support healthier sleep and eating patterns and guide family-based interventions.Article Evaluation of Barriers to the Integration of Renewable Energy Technologies into Industries in Türkiye(MDPI, 2026) Caloglu Buyukselcuk, Elif; Turan, HakanThe transition to renewable energy technologies is one of the most important ways to achieve the sustainable development goals (SDGs) of affordable and clean energy (SDG7); industry, innovation and infrastructure (SDG9); responsible production and consumption (SDG12); and climate action (SDG13). The widespread use of renewable energy technologies in developing countries will reduce dependence on imported fossil resources, increase industrial competitiveness, and support low-carbon development. Despite all their advantages, the integration of renewable energy technologies into industrial and domestic systems in developing countries remains slow due to a number of barriers. Financial constraints, technical and technological deficiencies, political restrictions and uncertainties, and organizational and managerial inadequacies are some of the barriers to the widespread adoption of renewable energy technologies. This study aims to identify, classify, and prioritize the barriers to the implementation of renewable energy technologies by applying multi-criteria decision-making methods in a fuzzy environment, with T & uuml;rkiye considered as a case study. The relative importance of the barriers identified using the Single-Valued Spherical Fuzzy SWARA method was assessed, and their interconnections and significance were systematically demonstrated. The findings will contribute to the development of policy and management strategies aligned with global sustainability goals, thereby facilitating a more effective and equitable transition to clean and resilient energy systems.Article Metformin Attenuates PTZ-Induced Seizures and Cognitive Impairment and Is Associated with Altered NOS/NO Signaling: Combined in Vivo and in Silico Evidence(Taylor & Francis Ltd, 2026) Ciltas, Arzuhan Cetindag; Sahin, Bilal; Hacisuleyman, Levent; Çetindağ Çiltaş, ArzuhanBackground: Epilepsy remains a major neurological disorder with high rates of drug resistance and cognitive decline. Repurposing neuroprotective drugs offers a promising approach. Metformin, a widely used antidiabetic agent, has shown anticonvulsant effects, yet its impact on nitric oxide synthase (NOS) isoforms in distinct brain regions remains unclear. Methods: Adult male Wistar rats were allocated into control, pentylenetetrazole (PTZ), or metformin+PTZ groups. Metformin (200 mg/kg, i.p.) was administered for 7 days before induction of acute PTZ seizures (45 mg/kg, i.p.). Seizure severity and latency were assessed using Racine's scale, and cognition was evaluated by the passive avoidance test (PAT). Nitric oxide (NO) and the expression of its synthesizing enzymes, inducible (iNOS), neuronal (nNOS), and endothelial (eNOS), were quantified in the cortex and hippocampus via enzyme-linked immunosorbent assay (ELISA). In silico analyses included target prediction and molecular docking to assess metformin - NOS interactions. Results: Metformin significantly reduced seizure severity, prolonged latency to the first myoclonic jerk, and prevented PTZ-induced memory impairment (all p < 0.001). These behavioral effects were accompanied by reductions in cortical and hippocampal nNOS and iNOS expression, decreased cortical eNOS levels, and lower NO accumulation. TargetNet predicted NOS isoforms among potential metformin targets, and docking indicated moderate binding affinity (-5.2 to -5.9 kcal/mol). Conclusion: Metformin exerted seizure-suppressing and cognition-preserving effects in an acute PTZ model, associated with reductions in NOS isoform expression and NO levels, suggesting altered NOS/NO signaling and supporting its potential as an adjunctive candidate for mitigating seizure-related neuronal dysfunction.Article Peloid Therapy Versus Hot Pack Treatment in Patients With Chronic Low Back Pain: Effects on Pain, Function, and Quality of Life(Romanian Assoc Balneology, 2025) Akkurt, Burcu; Alptekin, Hasan Kerem; Aydin, TeomanThis study aimed to compare the efficacy of peloid and hotpack for chronic low back pain (CLBP) due to lumbar disc herniation (LDH). Sixty individuals aged 18-50 years with CLBP due to LDH were randomized into two groups: peloid therapy (n=30) and hot pack therapy (n=30). Treatments were applied five days a week for 15 sessions, and all partici-pants received 20 minutes of lumbar TENS per session. Evaluations were conducted before and after treatment, including pain (VAS), Back Pain Functional Scale (BPFS), Oswestry Disability Index (ODI), quality of life (SF-36), range of motion, and finger-floor distance (FFD). Peloid group showed significant improvements in BPFS, physical functioning, role limitations due to emotional problems, vitality, emotional well-being, pain, and general health compared to the hot pack group (p<0.05). Both groups showed significant reducti-ons in VAS, ODI and FFD scores (p<0.05), with no significant between-group differences (p>0.05). In conclusion, while both treatments were effective in reducing pain and disabili-ty, peloid therapy provided superior improvements in functional status and quality of life compared to hot pack therapy.Article The Effect of Sportive Latin American Ballroom Dance on Foot and Ankle Posture(Amer Podiatric Med Assoc, 2025) Kayiskiran, Onurcan; Coskunsu, Dilber Karagozoglu; Isiklar, CagdasBackground: Correct use of the feet, step techniques, and positions constitute significant factors in the success of a dancer. Moreover, the type of dance has crucial effects on the posture of the foot and ankle. Therefore, the primary aim of our study was to determine whether there was a relationship between dancesport, dance experience (years), shoe-wearing time (hours), and shoe heel height (centimeters) in dance athletes performing Sportive Latin American Ballroom (SLAB) dance. Second, we aimed to compare the foot posture of SLAB dancers and nondancers with similar demographic characteristics. Methods: Twenty-six professional SLAB dancers and 26 nondancers who had similar demographic characteristics and did not use high-heeled shoes volunteered to take part in this study. Foot posture (using the Foot Posture Index [FPI]), foot pronation (using the navicular drop test [NDT]), tibiocalcaneal angle, hallux valgus angle (HVA) (using a goniometer), and ankle dorsiflexion range of motion (ROM) (using the weightbearing lunge test) were evaluated. Results: There was a positive moderate correlation between FPI score and shoe-wearing time on the dominant (P = .041; r = 0.40) and nondominant (P = .026; r = 0.43) sides. A positive very good correlation was found between shoe heel height and HVA (P < .001; r = 0.75). A negative good correlation was observed between years of dancing and nondominant ankle dorsiflexion ROM (P = .027; r =-0.43). When dancers and nondancers were compared, a statistically significant difference was found between FPI and NDT scores (P < .001). The FPI and NDT scores, tibiocalcaneal angle, HVA, and ankle dorsiflexion ROM were significantly greater in the dancer group compared with the nondancer group (P < .001) in all measurements of the dominant and nondominant sides. Conclusions: Revealing the relationship between dance experience and shoe-wearing time and the difference between the foot posture and deformities of athletes who perform SLAB dance and those of nondancers constitutes a pivotal endeavor that will increase awareness and knowledge among dancers and clinicians. (J Am Podiatr Med Assoc 115(6), 2025; doi:10.7547/24-030)