WoS İndeksli Yayınlar Koleksiyonu
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Article Determination of Age- and Gender-Specific Reference Values for Different Functional Tests with or without Cognitive Dual-Task in Young Adults: An Observational Study(Turkey Assoc Physiotherapists, 2025) Analay Akbaba, Yildiz; Emirza Cilbir, Cigdem; Poyraz Isleyen, Tugce; Evrendilek, Halenur; Gungor Eroglu, Nazli; Asena Yekdaneh, Aye; Gungor, Feray; Güngör, Nazlı; Emirza, Cigdem; İşleyen, Tuğçe Poyraz; Analay, Yıldız; Yekdaneh, Ayşe AsenaPurpose: To determine the age-and gender-specific reference values for the five functional tests performed with or without cognitive dual-task in young adults. Methods: In this cross-sectional observational study, a total of 107 participants were divided into four subgroups based on gender and age: females 18-25 years (G1), and 26-35 years (G2), and males 18-25 years (G3), and 26-35 years (G4). Participants completed the timed up and go test (TUG), 4 meter gait speed test, 10 meter walk test (10MWT), timed 25-foot walk test, and 1 minute sit-to-stand test (1MSTS) with and without dual-tasks. The mean value of each test was recorded. Results: Significant differences were observed in some functional tests. TUG was longer in G1 compared to G2 (p=0.019), 10MWT dual-task performance differed between G1 and G3 (p=0.041), and 1MSTS and 1MSTSdual scores were higher in G3 compared to G4 (p=0.044 and p=0.035, respectively). All dual-task conditions led to decreased performance compared to single-task conditions (p<0.001) Conclusion: The dual-task added to the performance tests changes the time, speed, and number of repetitions in healthy individuals, and these effects may vary according to age and gender. These reference values can guide clinical assessments of dual-task performance in this population.Article The Relation Between Personality Traits and Chemotherapy Symptoms of Cancer Patients(Marmara Univ, Inst Health Sciences, 2025) Özkan, İlknur; Taylan, Seçil; Eroglu, Nermın; Kolac, NurcanObjective:This study is important as it is one of the first studies to evaluate the relationship between personality traits and symptoms. Methods:This study was planned as descriptive and cross-sectional. The study was conducted with 468 patients who were voluntary to participate in the study and applied to the chemotherapy unit in a private oncology hospital in Istanbul between January-June 2019. Data were obtained using the Patient Information Form, Chemotherapy Symptom Assessment Scale (C-SAS), and Big Five Inventory. Results:The data were evaluated on computer environment. The mean age of the patients was 59.46±11.78 years, 59.8% are female, 35.7% were secondary school graduate, and 36.5% were housewives.When the mean scores of the big five inventory were examined, it was found that the mean scores were 29.72±3.38 in Extraversion subscale, 28.31±5.62 in Agreeableness subscale, 27.14±4.44 in Conscientiousness subscale, 25.26±3.31 in Neuroticism subscale, and 28.31±5.62 in Openness subscale. One-unit increase in neuroticism was determined to increase post-treatment nausea by 1.14 times, diarrhea by 1.28 times, change in sexual life by 1.14 times, feeling pessimistic and sad by 1.071 times, and feeling anxious and distressed by 1.08 times. Conclusion:It was observed that the personality traits of cancer patients were correlated with the symptoms they experienced related to chemotherapy and the symptoms decreased with the increase of openness, extraversion, agreeableness and conscientiousness characteristics and the symptoms increased with the increase of neuroticism characteristic.These results indicated that healthcare professionals should consider personnel characteristics of cancer patients while evaluating the symptoms they experienced and providing care.Article Citation - WoS: 1Citation - Scopus: 1A Comparative Study of Biochemical, Antimicrobial Effects and Phytochemical Composition Analysis of Glycyrrhiza Glabra L. Varieties Root Extracts(Marmara University, 2025) Sen, Ali; Servı, Hüseyın; Barak, Timur Hakan; Tekin, Fethullah; Şener, Azize; Marzi, Mahdi; Gülmez, GizemPlants are the significant global interest as alternative treatment sources with their biologically activecompounds. This study compares the chemical composition and the antioxidant, antidiabetic, and antimicrobialproperties of ethanol extracts of G. glabra L. two different varieties from different regions. The phytochemicalcompositions was determined using GC-MS. Additionaly, total phenolic (TPC), flavonoid (TFC) and triterpene (TTC)contents were determined. Glycyrrhizic acid contents were analysed by HPLC. G. glabra var. glandulifera (GF1) showedthe highest antioxidant activity. All extracts had strong antidiabetic effects, besides GF1 showing the highest effect. TheMIC values was determined against 8 bacterial and 1 yeast strain and values ranged from 2.500 to 0.500; 2.500 to 0.714;2.500 to 0.714 for G. glabra var. glabra (GB), GF1, G. glabra var. glandulifera (GF2) respectively. Phytochemical studies haveshown that TPC was 100.60±5.06, 127.90±0.30, 69.01±0.30 mg GAE /g extract; TFC was 80.07±0.15, 25.35±0.0, 16.58±0.31mg KE/g and TTC was 217.30±6.05,172.40±2.17, 126.30±4.50 mg OE/g extract for GB, GF1, GF2, respectively. GF1 inparticular has the highest glycyrrhizic acid content. This study will contribute to the creation of new treatment strategiesand potential therapeutic agents in addition to the use of G. glabra L. in traditional treatments. Our study is also apreliminary study for future studies.Article The Current Face of Mosaic Art: Flacking Istanbul Examples(Bursa Uludag University, 2025) Ural, A.G.French artist Ememem is an anonymous artist who started producing his artworks in the city of Lyon in 2016. The unknown street artist brought a contemporary perspective to the art of mosaic by decorating or patching the sidewalks with mosaic art. The term ‘flacking’, which he developed to express the combination of various fields such as upcycling, street art, mosaic art, is becoming increasingly common and attracting the attention of local municipalities. The aim of this study is to discuss the art of flacking, which is a face of mosaic art, which is a very old branch of art, derived from current terms. In terms of scope, examples from Istanbul will be tried to be found and compared with foreign examples. French artist Ememem is an anonymous artist who started producing his artworks in the city of Lyon in 2016. The unknown street artist brought a contemporary perspective to the art of mosaic by decorating or patching the sidewalks with mosaic art. The term ‘flacking’, which he developed to express the combination of various fields such as upcycling, street art, mosaic art, is becoming increasingly common and attracting the attention of local municipalities. The aim of this study is to discuss the art of flacking, which is a face of mosaic art, which is a very old branch of art, derived from current terms. Examples from around the world show how mosaic art can be transformed into impressive and meaningful projects in public spaces. However, it has been seen that modern mosaic trials are still insufficient in our country. It has been determined that for the development of mosaic art, various courses, workshops, contemporary examples to be applied in public spaces and initiatives should be made in order not to lose this valuable art. © (2025), All Rights Reserved.Article Relationship Between Resilience, Secondary Traumatic Stress and Work-Related Factors Among Mental Health Professionals(Kare Publ, 2025) Dikec, Gul; Tokatlıoglu, Tugba Sahın; Çetinkaya, Saadet; Yasar, SaadetObjectives: Resilience is the ability to maintain or rapidly recover mental health under stress. Mental health profes- sionals are often exposed to workplace stress through violence, emotional labor, restrictions, and traumatic stories. Secondary traumatic stress results from being affected by others’ traumatic experiences. Examining the relationship between resilience and secondary traumatic stress among mental health professionals is therefore essential. Methods: This descriptive study was conducted between February and April 2022. Data were collected using the Per- sonal Information Form, the Resilience Scale for Adults, and the Secondary Traumatic Stress Scale. Participants included 212 psychiatric and mental health nurses, 28 psychiatrists, 14 psychologists, and six social workers. Results: A significant positive relationship was found between resilience and secondary traumatic stress. The regres- sion model, including secondary traumatic stress, gender, educational status, willingness to work in mental health, job satisfaction, and unit of work, significantly predicted resilience. Conclusion: Secondary traumatic stress and work-related factors, such as willingness and satisfaction with working in mental health and the unit of work, were found to play an essential role in resilience. Institutional support and supervision may strengthen resilience, while reducing secondary traumatic stress can enhance motivation and well- being. Institutions are recommended to implement strategies that address these factors to improve both resilience and professional effectiveness.Article Evaluation of Dietary Habits and Related Parameters in a Group of Inpatients With Mental Disorders(Kare Publ, 2025) Dikec, Gul; Ata, Elvan Emıne; Özer, Duygu; Çalışkan, Mahinur Betül; Taliskan, Mahinur BetulObjectives: This study aimed to examine the dietary habits and related parameters of individuals with mental disorders. Methods: This study was descriptive and cross-sectional. The sample consisted of 94 individuals hospitalized in the psychiatric clinic of a hospital between June and December 2021. Data were collected using an information form cre- ated by the researchers. Results: Of the participants, 83% were male, and 25.5% had a chronic physical illness. The patients had a diagnosis of mental disorder for an average of 6.07 years. The most common side effect was an increase in appetite (36.4%). Additionally, 76.6% ate within 15 minutes, 93.6% consumed fish once a week or never, and 56.4% never exercised. In- dividuals who consumed home-cooked meals had lower BMI averages than those who consumed fast food. A weakly significant positive correlation was found between BMI and waist circumference averages and the duration of medica- tion use. Individuals with anxiety disorders had lower waist circumference, glucose, and LDL values compared to those with mood disorders. In contrast, individuals with psychotic disorders had significantly lower LDL levels than those diagnosed with mood disorders. Conclusion: Individuals with mental disorders were found to have inadequate and unbalanced nutrition, consuming diets rich in carbohydrates and low in protein, which negatively affected their parameters. Psychiatric nurses should evaluate the dietary habits of patients and provide counseling about healthy nutrition.Article Post Challenge Effects of Ozg-38.61.3 Gamma Irradiated SARS-CoV Vaccine on Organ Protection in Transgenic Mouse Model(Marmara University, Institute of Health Sciences, 2025) Telci, Dilek; Akpınar, Gürler; Tuğlu, Mehmet İbrahim; Ovalı, Ercüment; Oztatlıcı, Hulya; Şahin, Fikrettin; Demir, Sevda; Kancagi, Derya Dilek; Turan, Raife Dilek; Oztatlici, Mustafa; Karakus, Gozde Sir; Yurtsever, BulutObjective: Coronavirus disease 2019 (COVID-19) is an infectious outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) and virus-related deaths are increasing day by day. For this reason, vaccine studies and their urgent use are of great importance to prevent the pandemic. In this study, multi-organ damages caused by SARS-CoV-2 virus in human- angiotensin-converting enzyme type 2 (ACE2) transgenic mice and the protective effects of OZG-38.61.3 gamma irradiated SARS-CoV-2 vaccine against viral damage were investigated. Methods: For this purpose, transgenic K18-hACE2 BALB/c mice were randomly allocated into 4 groups, negative control group (NC), positive control group (PC, SARS-CoV-2 infected), and 2 different doses of OZG-38.61.3 vaccine (Challenge 1, dose of 10 13 and Ch2, 10 14 viral particle after SARS-CoV-2 infection). After the administrations, lung, heart and kidney tissues were examined by histopathological, immunohistochemical and TUNEL analysis. Results: Our results showed that the vaccine doses decreased the apoptosis, oxidative stress and inflammation parameters caused by virus in lung, heart, and kidney tissues. It was also found that the vaccine protected the expressions of tight junction proteins in the kidneys. Conclusion: According to our findings, it is suggested that the OZG-38.61.3 can be an effective and protective vaccine that can be safely used against the SARS-CoV-2 virus.Article Measuring Shoulder Abduction Strength Using 2 Different Dynamometers: Comprehensive Intrarater and Interrater Reliability and Validity(Turkish Assoc Orthopaedics Traumatology, 2025) Atli, Ecenur; Topaloglu, Mahir; Hosbay, Zeynep; Ozdincler, Arzu RazakObjective: The purpose of this study is to investigate the intrarater and interrater reliability of handheld dynamometer (HHD) measurements in assessing isometric muscle strength of the shoulder abductors and to compare these results with those obtained using a fixed dynamometer (FD). Methods: The study involved 25 voluntary participants, all over the age of 18, asymptomatic (with no injuries in the upper extremity), and not engaged in overhead sports. The participants were evaluated twice by 2 different testers who were experienced in orthopedic rehabilitation, at 90 degrees of shoulder abduction in the scapular plane. On the first measurement day, Tester 1 performed measurements using both HHD and FD, while on the second measurement day, both testers used only the HHD. A 3-to 7-day interval separated the 2 measurement sessions. Paired-samples t-tests were used to evaluate the systematic bias between the testers. Spearman's rank correlation coefficient, intraclass correlation coefficient, standard error of measurement, and minimal detectable change were calculated. The statistical significance level was accepted as P < .05. Results: Data from 22 participants (15 women, 7 men; mean age: 23.00 +/- 3.19 years) were analyzed, as 3 individuals did not attend the final assessment. A strong correlation (r = 0.772) was found between Tester 1's HHD measurements and FD, while a similarly strong correlation (r = 0.748) was observed for Tester 2's HHD measurements. Excellent intrarater reliability (intraclass correlation coefficient [ICC]= 0.941) was found between Tester 1's measurements, and excellent interrater reliability (ICC= 0.889) was found between testers. Conclusion: Handheld dynamometer has demonstrated excellent interrater and intrarater reliability and high validity for assessing shoulder abductor muscle strength in research and clinical use. Since the muscle strength of testers using the HHD may influence the results, the FD may be a more appropriate option when the study population is stronger than the testers. Studies involving different clinical populations and testers with varying experience levels are needed to improve the relevance of the results. Level of Evidence: Level III, Diagnostic Study.Article Determination of Post-Earthquake Trauma Level and Investigation of the Relationship with Physical Activity Status(Turkish Physiotherapy Association, 2025) Tosun, Anil; Yılmaz, Nergis; Luque, Demet Tekın De Las Penas; Tekin De Las Penas Luque, DemetAmaç: Çalışmanın amacı; 06 Şubat 2023’te meydana gelen Pazarcık-Elbistan merkezli depremler sebebiyle kişilerde oluşan travma düzeyinin, kişinin fiziksel aktivite durumu ile ilişkisini incelemektir. Aynı zamanda, kişilerde deprem sonrası ağrı varlığının sorgulanması ve bu durumun travma düzeyi ile ilişkisini ortaya koymaktır. Yöntem: Veriler çevrimiçi olarak Google formları aracılığıyla toplandı, 18-65 yaş arası 388 gönüllü katılımcı (299 kadın, 89 erkek) çalışmaya dahil edildi. Katılımcıların genel özelliklerini belirlemek için “Sosyodemografik Bilgi Formu”, travma düzeyini değerlendirmek için “Deprem Sonrası Travma Düzeyini Belirleme Ölçeği” (DSTDBÖ) ve fiziksel aktivite durumlarını belirlemek için “Uluslararası Fiziksel Aktivite Anketi Kısa Formu” (IPAQ-KF) kullanıldı. Bulgular: Deprem bölgesinde bulunma durumuna göre DSTDBÖ genel puan ortalamaları arasında anlamlı fark saptandı (p<0,001). Deprem bölgesinde bulunan 126 kişinin DSTDBÖ genel puan ortalaması 57,66±19,87 iken, bölgede bulunmayan 262 kişinin ortalaması 49,00±18,49 olarak bulundu. Spearman korelasyon analiziyle deprem bölgesinde olan ve olmayan bireylerin IPAQ-KF toplam puanları, DSTDBÖ alt faktör ve toplam puanları arasındaki ilişki incelenmiş olup sadece “Bilişsel Yapılandırma” alt faktörü ile IPAQ-KF toplam puanları arasında anlamlı bir ilişkiyi yansıtmayan negatif zayıf ilişki bulundu (deprem bölgesinde olanlar için Spearman korelasyon katsayı değeri =-0,18, p=0,042). Ve deprem sonrası ağrı yaşayan bireylerin DSTDBÖ puanları, ağrı yaşamayanlardan daha yüksek olarak saptandı (p=0,000). Sonuç: Bu çalışma ile deprem sonrası travma düzeyinin, fiziksel aktivite ile negatif ilişki gösterdiği belirlendi. İnaktif bireyler daha yüksek travma düzeylerine sahipken, minimal aktif bireylerde travma düzeyleri daha düşük bulundu. Bu bulgular, deprem sonrası fiziksel aktivitenin artırılmasının travma düzeylerini azaltmada etkili bir strateji olabileceğini göstermektedir. Bu alanda daha fazla araştırma, eğitim ve proje çalışmalarının yapılması gerekmektedir.Article Citation - WoS: 1Citation - Scopus: 1Synthesis, Characterization, and Antimicrobial Evaluation of Some Novel Hydrazinecarbothioamides(Galenos Publishing House, 2025) Güler, Emrah; Dinç, Harika Öykü; Dincel, Efe Doğukan; Güzeldemirci, Nuray Ulusoy; Başoğlu-ünal, Faika; Kuran, Ebru Dıdem; Başoğlu, Faika; Ulusoy Güzeldemirci, NurayObjectives: This study focused on synthesizing and characterizing novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety and evaluating their antimicrobial activity against several bacterial strains. The research aimed to identify key structural features that enhance antimicrobial efficacy through structure-activity relationship analysis and identify the minimum inhibitory concentration (MIC) of the most potent compounds to assess their potential for further development as antimicrobial agents. Materials and Methods: Nine novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety were synthesized by reacting 1,2,4-triazole derivatives with thiosemicarbazide precursors, and the products were characterized using infrared spectroscopy, proton nuclear magnetic resonance (1H-NMR), carbon-13 nuclear magnetic resonance (13C-NMR) spectroscopy, and elemental analysis. The antimicrobial activity of these compounds (5a-i) was tested against Klebsiella pneumoniae (K. pneumoniae), Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, and Pseudomonas aeruginosa (P. aeruginosa), using microdilution, disk diffusion, and broth microdilution methods. Dimethyl sulfoxide was used as a negative control, and Vancomycin and Meropenem were used as positive controls, with all results converted to µM for consistent analysis. Results: The synthesized thiosemicarbazide derivatives (5a-i) were confirmed to be structurally correct through Fourier-transform infrared spectroscopy, 1H-NMR, and 13C-NMR spectroscopy. Among the tested compounds, 5e (4-bromophenyl) and 5g (n-propyl) showed significant antimicrobial activity, with 5g exhibiting the strongest effects against S. aureus and P. aeruginosa. Other derivatives, such as 5b (4-NO2Ph), 5c (4-FPh), and 5d (4-ClPh), showed moderate activity, while no significant activity was observed against K. pneumoniae or E. faecalis. Conclusion: The study successfully synthesized a series of novel thiosemicarbazide derivatives with a 1,2,4-triazole moiety and evaluated their antimicrobial potential. Compounds 5e and 5g exhibited significant antibacterial activity, particularly against S. aureus and P. aeruginosa, with MIC values in the low micromolar range. These findings suggest that the compounds hold promise as potential antimicrobial agents, and further studies should focus on optimizing their efficacy and exploring their mechanism of action.