WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
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Article The Relation Between Personality Traits and Chemotherapy Symptoms of Cancer Patients(Marmara Univ, Inst Health Sciences, 2025) Özkan, İlknur; Taylan, Seçil; Eroglu, Nermın; Kolac, NurcanObjective:This study is important as it is one of the first studies to evaluate the relationship between personality traits and symptoms. Methods:This study was planned as descriptive and cross-sectional. The study was conducted with 468 patients who were voluntary to participate in the study and applied to the chemotherapy unit in a private oncology hospital in Istanbul between January-June 2019. Data were obtained using the Patient Information Form, Chemotherapy Symptom Assessment Scale (C-SAS), and Big Five Inventory. Results:The data were evaluated on computer environment. The mean age of the patients was 59.46±11.78 years, 59.8% are female, 35.7% were secondary school graduate, and 36.5% were housewives.When the mean scores of the big five inventory were examined, it was found that the mean scores were 29.72±3.38 in Extraversion subscale, 28.31±5.62 in Agreeableness subscale, 27.14±4.44 in Conscientiousness subscale, 25.26±3.31 in Neuroticism subscale, and 28.31±5.62 in Openness subscale. One-unit increase in neuroticism was determined to increase post-treatment nausea by 1.14 times, diarrhea by 1.28 times, change in sexual life by 1.14 times, feeling pessimistic and sad by 1.071 times, and feeling anxious and distressed by 1.08 times. Conclusion:It was observed that the personality traits of cancer patients were correlated with the symptoms they experienced related to chemotherapy and the symptoms decreased with the increase of openness, extraversion, agreeableness and conscientiousness characteristics and the symptoms increased with the increase of neuroticism characteristic.These results indicated that healthcare professionals should consider personnel characteristics of cancer patients while evaluating the symptoms they experienced and providing care.Article Citation - WoS: 7Citation - Scopus: 6The Potential Role of Boron in the Modulation of Gut Microbiota Composition: an in Vivo Pilot Study(Mdpi, 2024) Senturk, Nermin Basak; Kasapoglu, Burcu; Sahin, Eray; Ozcan, Orhan; Ozansoy, Mehmet; Ozansoy, Muzaffer Beyza; Sahin, FikrettinBackground/Objectives: The role of the gut microbiome in the development and progression of many diseases has received increased attention in recent years. Boron, a trace mineral found in dietary sources, has attracted interest due to its unique electron depletion and coordination characteristics in chemistry, as well as its potential role in modulating the gut microbiota. This study investigates the effects of inorganic boron derivatives on the gut microbiota of mice. Methods: For three weeks, boric acid (BA), sodium pentaborate pentahydrate (NaB), and sodium perborate tetrahydrate (SPT) were dissolved (200 mg/kg each) in drinking water and administered to wild-type BALB/c mice. The composition of the gut microbiota was analyzed to determine the impact of these treatments. Results: The administration of BA significantly altered the composition of the gut microbiota, resulting in a rise in advantageous species such as Barnesiella and Alistipes. Additionally, there was a decrease in some taxa associated with inflammation and illness, such as Clostridium XIVb and Bilophila. Notable increases in genera like Treponema and Catellicoccus were observed, suggesting the potential of boron compounds to enrich microbial communities with unique metabolic functions. Conclusions: These findings indicate that boron compounds may have the potential to influence gut microbiota composition positively, offering potential prebiotic effects. Further research with additional analyses is necessary to fully understand the interaction between boron and microbiota and to explore the possibility of their use as prebiotic agents in clinical settings.