WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6

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COAR Access Rights: search.filters.coarAccessRights.metadata only accessStart date: 2020

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  • Conference Object
  • Conference Object
    Preclinical Applications of Lentiviral Gene Therapy in X-Linked Agammaglobulinemia (XLA)
    (Springer Nature, 2025) Sahin, Ilayda; Kiykim, Ayca; Ocak, Suheyla; Eken, Yunus; Onder, Gizem; Gundogdu, Merve; Ng, Yuk Yin
  • Article
    Ramadan Fasting and Seizure Activity in Adults with Epilepsy: A Systematic Review and Meta-Analysis
    (Academic Press Inc Elsevier Science, 2026) Ibrahim, Ismail A.; Shaaban, Sally; Elewa, Mandy; Rahman, Muhammad Samir Haziq Bin Abd; Mohamed, Lobna Ahmed; Talaia, Ahmed M.; Khoo, Ching Soong; Haziq bin Abd Rahman, Muhammad Samir
    Purpose: Ramadan fasting in Muslims entails abstaining from food and fluids from dawn to sunset, which can influence sleep patterns, medication timing, and food intake. Building on evidence that ketogenic diets and intermittent fasting may improve seizure control, we aim to analyze the link between intermittent Ramadan fasting in adults with epilepsy and seizure activity. Method: We systematically searched PubMed, Scopus, Web of Science, Cochrane Library, and Embase between 2000 and January 2025 for articles that appeared between these dates. The terms used for searching included fasting in Ramadan with epilepsy or seizures. The seizure frequency and seizure status of the participants are the outcomes that we analyzed. Two reviewers independently screened and extracted data, with a third resolving any differences that arose between them. Meta-analysis was done using the random-effects model with statistical heterogeneity using the I2 statistic. Results: Of the 1485 articles, only eight were found to be relevant, and 4 of these included 564 patients who met the inclusion criteria. The analysis of the pooled data demonstrated that 61.1% of patients remained seizure-free throughout Ramadan (95% CI: 38.8%-83.4%), with considerable heterogeneity (I2 = 87.7%). Seizure risk was higher in patients on polytherapy with poor baseline seizure control, increased fasting times, or high potassium levels. In contrast, extended seizure-free intervals and increased sleep duration pre-Ramadan were good predictors of safe fasting, and each seizure-free week increased the chance of remaining seizure-free by 10%, as did each extra hour of sleep by 30%. Seizure frequency increases were caused by interruption of daily rhythms, psychological tension, tiredness, and extended fasting. Conclusion: While many patients remained seizure-free during Ramadan, high study variability highlights the need for standardized research. With proper medical supervision, fasting may be safely practiced for selected epilepsy patients.
  • Conference Object
    Comparison of the Effectiveness of Connective Tissue Massage and Classical Massage in Patients with Migraine
    (Elsevier, 2025) Ozdincler, Arzu Razak; Kaya, Begum Kara; Kahleogullari, Elif
  • Article
    Telerehabilitation Transforms Recovery: Elevating Outcomes for Lower Limb Amputees
    (Wolters Kluwer Health, 2026) Ozturk, Basar
    Background: Telerehabilitation provides a viable alternative for individuals facing barriers to in-person rehabilitation because of transportation issues and physical limitations. It enables remote monitoring and guidance, allowing patients to continue rehabilitation at home. Objective: This study aimed to assess the effectiveness of a telerehabilitation program in improving physical and psychological outcomes for lower limb amputees and to evaluate adherence to a home-based exercise program delivered via video. Study design: A randomized controlled trial. Methods: Sixty participants with lower limb amputations were randomized to an experimental group (telerehabilitation) or a control group (standard care). The intervention involved a 4-week supervised phase followed by a 4-week unsupervised phase. Primary outcomes were physical capacity, measured by the Six-Minute Walk Test (6MWT), and psychological status, assessed using the Hospital Anxiety and Depression Scale. Secondary outcomes included adherence rates and patient satisfaction. Results: The experimental group showed significant improvements in 6MWT distance and Hospital Anxiety and Depression Scale scores compared to the control group. The mean 6MWT distance increased by 20% from baseline to the end of the supervised phase (P < 0.01) and was maintained during the unsupervised phase. Anxiety and depression scores significantly decreased (P < 0.05). Adherence was higher during the supervised phase (85%) but dropped during the unsupervised phase (60%). Conclusions: Telerehabilitation significantly improved physical and psychological outcomes for lower limb amputees. High adherence during the supervised phase emphasizes the importance of clinician support, whereas strategies are needed to sustain long-term engagement during the unsupervised phase.
  • Conference Object
    The Homeostasis-Enrichment (HEP®) Approach: A Novel Early Intervention Model for OT
    (Amer Occupational Therapy Assoc, Inc, 2025) Balikci, Aymen; Sirma, Gamze Cagla; May-Benson, Teresa A.
  • Article
    Evaluation of the Effect of Simulation-Based Training Provided to Nurses in the Hospital Environment on Child Neglect and Abuse: Quasi-Experimental Research
    (Elsevier Science Inc, 2026) Sanci, Yagmur; Genc, Canan; Kokkiz, Rukiye
    Background: Child neglect and abuse are major public health concerns, and nurses play a critical role in early recognition. Simulation-based training is a promising method to strengthen knowledge and preparedness. Methods: This quasi-experimental pretest-posttest study was conducted with 20 nurses working in a pediatric emergency unit of a state hospital between March and April 2024. Data were collected using a socio-demographic form and the "Scale for Determining the Knowledge Level of Nurses and Midwives in Diagnosing the Symptoms and Risks of Child Abuse and Neglect." Nurses participated in simulation-based training with a structured scenario, followed by debriefing and posttest. Results: Knowledge scores significantly increased after training, particularly in recognizing physical and behavioral symptoms of abuse. However, improvements were limited in identifying children at higher risk of neglect and abuse. Conclusion: Simulation-based training enhances nurses' knowledge of child abuse recognition and should be integrated into nursing education and in-service programs to improve clinical preparedness. (c) 2026 International Nursing Association for Clinical Simulation and Learning. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
  • Article
    Assessment of the Nutritional Status of Syrian Refugee Women in the Lactation Period
    (Sage Publications Inc, 2026) Isik, Tulay; Garipagaoglu, Muazzez
    Background: The Syrian civil war has caused large-scale displacement, with many Syrian refugee women migrating to T & uuml;rkiye. Lactation is a critical period requiring adequate nutrition for maternal and infant health. However, data on the nutritional status of lactating Syrian refugee women are limited. Aim: This study aimed to assess the nutritional status of lactating Syrian refugee women who migrated to T & uuml;rkiye due to the Syrian civil war. Methods: A cross-sectional study was conducted between October 5, 2017, and January 29, 2018, with 102 lactating Syrian refugee women with infants aged 0-6 months attending the Istanbul Al Farah Child and Family Support Center. Participants were selected using convenience sampling. Inclusion criteria were being a Syrian refugee woman in the lactation period, having an infant aged 0-6 months, and volunteering to participate in the study. Women with chronic illnesses or metabolic disorders were excluded. Data were collected through face-to-face interviews with the assistance of a translator, using a structured Turkish questionnaire covering demographic information, anthropometric measurements, and 3-day dietary records. Dietary intake was analyzed with the BEBIS9 program and compared to the T & uuml;rkiye Nutrition Guide recommendations. Although the dietary data were collected in 2017-2018, the analysis was conducted using the most up-to-date national guidelines to reflect current public health priorities. Results: Participants (n = 102) had an average age of 27.9 +/- 5.7 years, BMI of 27.3 +/- 4.6 kg/m(2), and monthly income of 1267 TL. Their daily energy intake was 1593.7 +/- 556.5 kcal/day. A large proportion of participants had inadequate intake of micronutrients, with the highest insufficiency observed for pyridoxine (88.2%), followed by vitamin A (81.4%), vitamin C (76.5%), thiamine (71.5%), riboflavin (63.7%), folic acid (81.4%), vitamin B12 (72.6%), iron (62.8%), and zinc (68.6%). Women with higher BMI in early lactation consumed more fat (p < 0.05). Significant associations were found between micronutrient intake and sociodemographic factors (p < 0.05). However, due to the small sample size and use of convenience sampling, the generalizability of the findings is limited. Future studies with larger and more representative samples are needed to confirm these results. Conclusion: Syrian refugee women in the lactation period showed inadequate intake of energy and essential micronutrients, likely due to poor socioeconomic and living conditions. Interventions such as culturally sensitive nutrition education, postpartum micronutrient supplementation, and improved access to migrant-friendly healthcare services are needed. Additionally, targeted policies and sustainable public health nutrition programs-such as food voucher schemes, fortified food distribution, and maternal support groups-should be developed in collaboration with health institutions and NGOs to improve maternal and infant health outcomes in this vulnerable population.
  • Article
    The Role of High-Fidelity Simulators in Vascular Surgery Training: A Systematic Review
    (Springer Nature, 2026) Abdelkader, Rem Ehab; Amgad, Ahmed; Alshurman, Saba Hussein; Almanaseer, Ghadeer M.; Manoj, Rachel Mary; Iqbal, Uzair; Ibrahim, Ismail A.
    BackgroundIn vascular surgery, endovascular procedures demonstrated lower morbidity and shorter hospital stays. However, learning these skills is highly challenging. A new method that offers secure, controlled settings for skill development is simulation-based training.AimThis systematic review aims to examine the different high-fidelity simulation programs and their effectiveness in enhancing endovascular skills among vascular surgery trainees.MethodsA comprehensive literature search was conducted across PubMed, SCOPUS, Cochrane CENTRAL, and Web of Science using PRISMA guidelines. We included all studies of all designs involving high-fidelity simulation in vascular surgery training. The eligibility criteria focused on studies assessing simulation interventions comparing pre- and post-course outcomes. Data extraction was done manually using Excel spreadsheets by two independent reviewers, and quality assessment was performed using a 19-point scale. The studies were also evaluated using Kirkpatrick's adapted hierarchy based on their educational impact.ResultsA total of 35 studies met the inclusion criteria, covering a range of simulation modalities, including virtual reality, augmented reality, and physical simulators. The findings demonstrated significant improvements in procedural skills, operation time, operative errors, and participant's confidence across all training levels. However, there were great variations in study methods and design, as well as a lack of a specific framework for skill assessment.ConclusionFor endovascular training, high-fidelity simulation is a useful tool for skill development. However, Standardized training techniques and additional research are needed to assess long-term skill retention.
  • Article
    Effect of Gender Equality Education on Health Students Gender Perceptions and Roles: A Randomized Controlled Trial
    (Routledge Journals, Taylor & Francis Ltd, 2026) Isbay Aydemir, Beyzanur; Sahin Tokatlioglu, Tugba; Kuru Akturk, Nur Bahar; Dikec, Gul
    Aim To evaluate the impact of community gender equality education program on health sciences students' perceptions of gender, gender roles, and their awareness of social norms and gender inequality. Design A single-blind, two-arm, parallel-group randomized controlled trial. Methods Conducted with 70 students at a foundation university in Istanbul (2024-2025). The intervention group received two weeks structured training. Data were collected using the Perception of Gender Scale (PGS) and Gender Roles Attitude Scale (GRAS). Results No significant differences were observed at baseline. Post-intervention, the intervention group showed significant improvements in PGS and GRAS scores, while no change was found in the control group. Conclusion Short-term gender equality education program effectively improved students' gender perceptions and attitudes.