WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
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Article Citation - WoS: 1Safety and Efficacy of Depatuxizumab Mafodotin Monotherapy or in Combination With Temozolomide in Patients With/Without EGFR-Amplified Recurrent Glioblastoma: A Systematic Review(Lippincott Williams & Wilkins, 2025) Moghib, Khaled; Hassan, Malak A.; Eljadid, Ghaith Y.; Salomon, Izere; Algazar, Mansour A.; Abu Arafeh, Muhannad Wael; Ibrahim, Ismail A.This study aimed to assess the safety and efficacy of depatuxizumab mafodotin as a monotherapy or in combination with temozolomide in patients with recurrent epidermal growth factor receptor (EGFR)-amplified glioblastoma multiforme, focusing on overall survival (OS) and progression-free survival (PFS). A comprehensive literature search was conducted across PubMed, Cochrane Library, Web of Science, and Scopus databases up to August 2024. Randomized controlled trials (RCTs) and observational studies were included, comparing depatuxizumab mafodotin alone or with temozolomide in patients with and without EGFR amplification. Data extraction encompassed participant demographics, treatment regimens, and clinical outcomes. Of 102 screened publications, 10 RCTs and cohort studies involving 1431 patients met the inclusion criteria. The included studies examined depatuxizumab mafodotin as a standalone therapy and in combination with other agents, revealing OS ranging from 5 to 14 months and considerable variability in PFS. While depatuxizumab mafodotin shows the potential to improve survival outcomes, the heterogeneity in results highlights the need for further research. Future studies should refine patient selection criteria and explore alternative therapeutic combinations, such as depatuxizumab mafodotin with gemcitabine or cisplatin, to optimize treatment strategies.Article Citation - WoS: 3Need To Address the Gender Disparities in Neurosurgery in India(Lippincott Williams & Wilkins, 2024) Anand, Ayush; Ibrahim, Ismail A.; Kathayat, Priyangi; Ansari, Ayesha; Aggarwal, Yash; Wahi, Riddhpreet Kaur; Rustagi, Sarvesh[No Abstract Available]Article Citation - WoS: 3Nipah Virus Transmission: a Persistent Threat To Public Health Demanding Rapid Diagnosis, Innovative Therapeutics, Vigilance, and Research Progress(Lippincott Williams & Wilkins, 2024) Islam, Md. Aminul; Ibrahim, Ismail A.; Hemo, Mizbahul Karim[No Abstract Available]Article Citation - WoS: 7Citation - Scopus: 9The Relationship Between Perceived Quality of Care and the Patient Safety Culture of Turkish Nurses(Lippincott Williams & Wilkins, 2022) Karaca, Anita; Akin, Semiha; Harmanci Seren, Arzu KaderBackground Evaluating nurses' perceived quality of care and safety culture is an essential part of the nursing practice and critical to improving the quality of nursing care. Purpose This study aimed to examine the relationship between perceived quality of care and Turkish nurses' patient safety culture. Methods This was a descriptive cross-sectional study. The data were collected from a foundation university hospital in Istanbul. The sample consisted of 116 nurses, and data were collected using the Caring Behaviors Inventory-24 and Patient Safety Culture Scale. The nurses were asked to complete the questionnaires. Results The mean age of participating nurses was 25.95 (SD = 6.72) years. The mean duration of professional experience of the participants was 6.37 (SD = 6.05) years. Most (72.4%) of the participants were women who had graduated from vocational high schools (52.6%) and were working in the neonatal intensive care unit (37.9%). The highest mean subdimension score on the Caring Behaviors Inventory-24 was 5.78 (SD = 0.43) for the knowledge and skills subdimension. The highest mean subdimension score on the Patient Safety Culture Scale was 3.55 (SD = 0.48) for the unexpected event and error reporting subdimension. Statistically significant correlations were found between Caring Behaviors Inventory-24 and Patient Safety Culture Scale scores (r = .553, p < .01), with the lowest correlation found between the employee behavior and knowledge and skills dimensions (r = .305, p = .001). The highest statistically significant correlation coefficients that were found were between the Patient Safety Culture Scale total scores and the connectedness dimension of the Caring Behaviors Inventory-24 (r = .58, p < .001). Conclusions/Implications for Practice Nurses perceive patient care positively and have a positive perception of safety culture. Evaluating the perceived quality of care and patient safety culture perceptions will help prevent adverse events related to patient care and improve the quality of care.