WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6
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Article Effects of Left and Bilateral Transcutaneous Auricular Vagus Nerve Stimulation on Pain, Mood, and Autonomic Nervous System in Female Patients With Fibromyalgia: a Randomized Controlled Trial(Taylor & Francis Inc, 2025) Akkurt, Mustafa Ferit; Ozden, Ali Veysel; Akkurt, Halil Ekrem; Akkurt, Burcu; Bildik, CelaleddinIntroduction: Fibromyalgia Syndrome (FMS) is a complex disease characterized by widespread pain, fatigue, emotional disturbances, and autonomic dysfunction. Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) has emerged as a potential noninvasive approach to modulate FMS-related symptoms. Purpose: To compare the effects of left and bilateral taVNS on pain, mood, functionality, and autonomic nervous system (ANS) activity in individuals with FMS. Methods: Forty female individuals with FMS were assigned to either a left (n = 20) or a bilateral (n = 20) taVNS group. Both received 11 sessions of taVNS targeting the tragus and concha regions (30 minutes each, 25 Hz, 300 mu s) over nonconsecutive days, excluding weekends and menstrual periods. Visual Analog Scale (VAS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Fibromyalgia Impact Questionnaire (FIQ) were assessed. ANS activity was evaluated via heart rate variability (HRV). After 11 sessions of taVNS, a 2-week follow-up was performed. Results: No significant differences were observed between groups except for FIQ and BAI on day 28 (p = .002-0.008). Both groups showed significant within-group improvements in VAS (r = 0.87-0.94; p < .001), BDI (r = 0.46-0.71; p < .001), FIQ (r = 0.95-0.99; p < .001), and BAI (r = 0.69-0.94; p < .001) scores. Parasympathetic Nervous System (PNS) (p = .365-0.776) and Sympathetic Nervous System (SNS) (p = .598-0.880) indices, which are the subparameters of HRV, showed no significant between-group differences, with small effect sizes (r < 0.15). Conclusion: Both stimulation protocols effectively reduced pain and improved mood and functionality in fibromyalgia, indicating a safe, noninvasive adjunctive treatment option. Clinicaltrials.gov: (Identifier: NCT06871306).Article A Randomized Trial of Cervical Stabilization Exercise Training via Telerehabilitation for Migraine(W.B. Saunders, 2025) Dusgun, Elif Sena; Karahan, Nesrin; Toprak Çelenay, Şeyda; Celenay, Seyda ToprakPurpose: To compare the effects of cervical stabilization exercise training via telerehabilitation (CSET-T) in addition to standard treatment on pain, forward head posture, cervical mobility, muscle performance, functional status, sleep quality, and quality of life in individuals with migraine in comparison to the standard treatment alone. Methods: The control group (n = 20) received standard treatment alone (medication+recommendations). The stabilization group (n = 20) was given CSET-T in addition to standard treatment 3 days a week for 8 weeks. Pain characteristics were assessed by using a pain diary, whereas forward head posture and cervical mobility were measured using a goniometer, cervical muscle performance (CMP) by using a pressure biofeedback unit, functional status by using the Migraine Disability Assessment Scale (MIDAS), sleep quality by using the Jenkins Sleep Scale (JSS), and quality of life by using the Headache Impact Test-6 (HIT-6). Results: Given the group-time interaction, it was found that pain frequency, intensity, duration, MIDAS, JSS, and HIT-6 scores decreased more significantly in the stabilization group when compared to the control group (p < .05). Moreover, the craniovertebral angle, cervical range of motions, and CMP values increased significantly more in the stabilization group (p < .05). It was found that there was no statistically significant difference between the groups in terms of compliance with standard treatment (p = .665). Conclusions: The study revealed that CSET-T in addition to standard treatment is superior to standard treatment alone in reducing pain, improving forward head posture, cervical mobility, muscle performance, functional status, and quality of life in individuals with migraine. © 2025 Elsevier B.V., All rights reserved.Conference Object Is It Fear or Pain Understanding It's Impact on Physical Performance and Rumination in Children with Rheumatic Diseases(Elsevier, 2025) Donmez, I.; Arman, N.; Yekdaneh, A.; Albayrak, A.; Acikgoz, Y.; Ayaz, N. AktayArticle Citation - WoS: 2Citation - Scopus: 2Efficacy of Different Exercises in Women With Fibromyalgia Syndrome: a Randomised Controlled Trial(Clinical & Exper Rheumatology, 2025) Sevgin, O.; Bugday, B.; Baykara, R. Aydogan; Gunendi, G.; Akkurt, B.; Atasoy, H.; Karamancioglu, B.Objective The objective of this study was to evaluate the impact of aerobic exercise, resistance exercise combined with aerobic exercise, and yoga exercises combined with aerobic exercise on pain and disease activity in patients with fibromyalgia syndrome (FM). Methods The study population comprised 60 individuals with FM who met the inclusion criteria. The participants were randomly assigned to one of three groups. The first group underwent aerobic exercise (n=20), the second group combined aerobic exercise with yoga (n=20), and the third group engaged in aerobic and resistance exercise (n=20). All exercise interventions were conducted for a total of 12 weeks. Disease activity was evaluated using the Fibromyalgia Impact Questionnaire (FIQ), while pain status was assessed with the Melzack-Melzack Pain Questionnaire (MMPQ). All assessments were conducted before and following the completion of the exercise programme. The clinical trial number of this study is NCT06006494. Results The measurements of the aerobic exercise and yoga group were significantly lower than those of the aerobic and resistance exercise group. A statistically significant difference was observed between the groups in terms of post-treatment MMPQ scores. The measurements of the aerobic exercise and yoga group were significantly lower than those of the aerobic exercise only and aerobic and resistance exercise groups. No statistically significant difference was observed between the post-treatment MMPQ scores of the aerobic and aerobic resistance exercise groups. Conclusion The combination of aerobic exercise and yoga is more efficacious in the treatment of FM than aerobic exercise alone or a combination of resistance exercises and aerobic exercise.Article Comparison of the Effect of Maternal Breast Milk Odor, Facilitated Tucking, and Nonnutritive Sucking Applied To Preterm Neonates During Heel Stick on Pain and Physiological Parameters: a Randomized Controlled Trial(Mary Ann Liebert, inc, 2024) Akbari, Negarin; Mutlu, Birsen; Khoddam, HomeiraBackground: Preterm infants in the neonatal intensive care unit (NICU) frequently undergo painful procedures, which can lead to both short-term and long-term complications, including potential mortality. Effective pain management is crucial in this context. Although numerous studies have explored non-pharmacological pain relief methods for preterm infants, no research has simultaneously compared the effects of maternal breast milk odor, facilitated tucking, and nonnutritive sucking. Aim: This study aims to comparatively investigate the efficacy of nonnutritive sucking, facilitated tucking, and maternal breast milk odor in reducing pain in preterm neonates during heel sticks. Methods: A randomized controlled trial was conducted in a tertiary-level NICU with 144 preterm neonates (gestational age 31-36 weeks) requiring heel sticks. The infants were randomly assigned to four groups: control, nonnutritive sucking, facilitated tucking, and maternal breast milk odor. Pain and physiological parameters were assessed through video recordings of the procedures and scored at 1-minute intervals using the Premature Infant Pain Profile and Data Evaluation Form. Data were collected at baseline and at 1, 2, and 3 minutes before, during, and after the heel stick. Results: The study found significant effects of the interventions on physiological parameters and pain (heart rate: F = 7.5, p < 0.001; oxygen saturation: F = 16.39, p < 0.001; respiratory rate: F = 6.56, p < 0.001; pain: F = 61.45, p < 0.001). Facilitated tucking resulted in significantly lower pain scores (6.61 +/- 1.44) compared with the control group (14.22 +/- 3.61), maternal breast milk odor (12.22 +/- 3.08), and nonnutritive sucking (10.41 +/- 1.71) (p < 0.001). Conclusions: All interventions demonstrated effectiveness in maintaining physiological stability and alleviating pain. Nevertheless, the intervention identified as most effective in reducing pain was facilitated tucking group.Article Citation - WoS: 8Citation - Scopus: 12The Effect of Aromatherapy and Su Jok Interventions on Post-Cesarean Pain(Elsevier Sci Ltd, 2022) Simsek, Hulya Elmali; Alpar, Sule Ecevit; Ecevi̇t Alpar, Şule; Elmali Şi̇mşek, HülyaObjective: The aim of this study was to determine the effect of aromatherapy and Su Jok interventions as non-pharmacological methods of relieving pain after cesarean section. Materials and methods: This randomized controlled trial was conducted with 120 women who had cesarean delivery in the gynecology and obstetrics department of a training and research hospital between February 9 and October 2, 2019. The participants were allocated to the aromatherapy group, Su Jok group, Su Jok and aromatherapy group, or control group using block randomization based on parity. Su Jok was performed using buckwheat seed; aromatherapy was applied using lavender, eucalyptus, or rose oil. Data were collected using a participant information form and pain was assessed using the Visual Analog Scale. Results: There was no significant difference between the groups in mean pain levels before or after the intervention, although the control group had less initial pain compared to the intervention groups. However, all three intervention groups showed significant decreases in pain levels immediately and 30 min after the intervention compared to pre-intervention levels (p < 0.05). The intervention in all three groups reduced the level of pain. In particular, the pain level of the Su Jok group reached from moderate to mild. There was no significant change in the control group. Conclusions: Aromatherapy and Su Jok interventions performed separately and simultaneously in addition to routine hospital care were more effective in reducing post-cesarean pain than routine care alone.