Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/7

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  • Article
    Citation - Scopus: 1
    Critical Spatial Reasoning in Designing: A Visitor’s Centre Relating to Beylikdüzü Archaeological Site, Istanbul
    (Jomard Publishing, 2025) Agboola, Oluwagbemiga Paul; Uzun, Türkan İrgin; Çakır, Hülya Soydaş
    Architectural Design Studio helps students develop the skills to abstract, conceptualise and analyse space. This paper addresses the process of developing critical thinking and design, focusing on the central project, relating to Beylikdüzü Archaeological Excavation Site in Istanbul, Turkiye. This project provides the opportunity for students to explore the context, restrictions of the site and metaphors in design while operating more as an incubator for collaboration than a formal studio course. More specifically, the project aims to improve links between the welcome centre and the archaeological site and hence fills a research gap by exploring the value of producing three-dimensional thinking able to deliver architectural solutions that are new to the context. The purpose of the study is to investigate students' abilities in site analysis, topography and environment for appropriate designs that are functional and sustainable. Methods such as SWOT analysis and topographical studies are incorporated within the framework to propose a unified design solution that is sensitive to both the archaeological site and cultural attachment. The results show integrated and innovative solutions that combined the welcome centre with the archaeological area, helping to enrich the visitor experience. Cultural preservation and taking into consideration the value of archaeological sites to integrate them with minimum damage in new architectural interventions is another aspect seen through this project. © 2025 Elsevier B.V., All rights reserved.
  • Article
    Citation - WoS: 2
    Citation - Scopus: 2
    Twenty-Year Course of Antifungal Resistance in Candida Albicans in Türkiye: A Systematic Review and Meta-Analysis
    (MDPI, 2025) Kilbas, Imdat; Kahraman Kilbas, Elmas Pinar; Horhat, Florin George; Ciftci, Ihsan Hakki
    This study aimed to systematically evaluate the resistance rates of Candida albicans to various antifungals based on studies conducted in Turkiye and published between 2005 and 2025 and to analyze the factors contributing to resistance. A systematic literature search was conducted using various keywords in electronic databases (PubMed, Embase, Web of Science, EBSCO, Scopus, Turk Medline and Google Scholar). A total of 42 studies were included in the meta-analysis according to the determined criteria. The quality of the studies was assessed using the Joanna Briggs Institute checklist, and the analyses were performed using appropriate statistical software. The highest resistance rates for fluconazole, itraconazole, and voriconazole were observed in the Aegean and Marmara regions. In the analyses performed with the random-effects model, heterogeneity was found to be high for itraconazole, fluconazole, posaconazole, voriconazole, and caspofungin, and the strongest explanatory variable of this heterogeneity was the geographical region variable. In our study, we determined that antifungal resistance in C. albicans strains in Turkiye is generally low; however, an increasing trend has been observed over the years, especially in amphotericin B resistance. Although the low resistance rates to major antifungal agents such as fluconazole, voriconazole and echinocandins are promising, regional differences and methodological heterogeneity necessitate the development of treatment strategies based on local data.