Scopus İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/7

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  • Article
    Comparative Evaluation of Vision Transformers and Convolutional Networks for Breast Ultrasound Image Classification
    (Open Exploration Publishing Inc, 2026) Naral S.; Cakmak Y.; Pacal I.; Pacal, Ishak; Cakmak, Yigitcan; Naral, Suleyman
    Aim: Interobserver variability continues to limit the consistency of breast ultrasound interpretation. This study compares two Vision Transformer (ViT) models and two Convolutional Neural Network (CNN) models for automated three-class breast ultrasound classification, with a specific focus on the tradeoff between predictive performance and computational efficiency. Methods: Swin Transformer Base and DeiT Base were evaluated alongside InceptionV3 and MobileNetV3 Large using the public Breast Ultrasound Images (BUSI) dataset, which contains 780 images labeled as benign, malignant, and normal. A consistent on-the-fly augmentation pipeline was applied during training to promote robustness and reduce sensitivity to incidental image variations. Results: Swin Transformer Base achieved the highest test accuracy (0.9167) and F1 score (0.8981). MobileNetV3 Large reached an accuracy of 0.8583 with substantially lower computational demand. The efficiency contrast was pronounced, with Swin requiring 30.33 GFLOPs versus 0.43 GFLOPs for MobileNetV3 Large. Conclusions: On this benchmark, ViT models can yield higher classification performance, while lightweight CNNs offer a strong efficiency profile that may better match deployment-constrained settings. These results suggest that model selection should be guided by both predictive accuracy and operational feasibility within the target clinical workflow. © The Author(s) 2026.
  • Article
    Psychological Effects of Robotic Rehabilitation in Individuals With Spinal Cord Injury: A Narrative Review
    (BMC, 2025) Ibrahim, Ismail A.; Mounir, Mennatallah M.; Hussein, Omar; Parnian, Nadieh; Sefertas, Ece; Ravanbod, Amin; Arican, Tuna Eren
    IntroductionSpinal cord injury (SCI) is associated with severe physical, psychological, and social burdens. Robotic rehabilitation, especially robotic-assisted gait training, is increasingly used to improve functional recovery. Nonetheless, its psychological effects which are key to motivation, compliance, and long-term prognosis have received little scrutiny.MethodsWe conducted a narrative review across five databases (PubMed, Web of Science, Scopus, Cochrane, Embase) from inception to January 2025. Studies were included if they evaluated robotic rehabilitation in SCI and reported psychological outcomes. Findings were synthesized thematically into domains of anxiety/technophobia, motivation/engagement, self-efficacy/dependence, and frustration/quality of life.ResultsRobotic systems frequently improved autonomy, motivation, and self-confidence, which corresponded to less depression and a better quality of life. Nevertheless, negative effects including technophobia, frustration from technological malfunction, and loss of self-efficacy from excessive dependence were found. Patient experiences ranged: empowerment and new optimism were reported by some patients, whereas others experienced the devices as complicated, emotionally alienating, or inadequately adjustable.DiscussionRobotic rehabilitation has a dual psychological effect. On one hand, it encourages engagement and emotional resilience; on the other, it carries risks of interdependence and diminished autonomy. There are ethical issues to be resolved access disparities, data protection, and preserving human connection that require careful management. The inclusion of psychological screening, education of patients, and specific goal-setting within protocols can maximize results.ConclusionRobotic rehabilitation is highly capable of promoting progress after SCI if psychological considerations are completely incorporated into rehabilitation interventions. A multimodal approach that is interdisciplinary and ethically solid is required to achieve optimized functional improvement as well as psychosocial health.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    A Comparative Study of Biochemical, Antimicrobial Effects and Phytochemical Composition Analysis of Glycyrrhiza Glabra L. Varieties Root Extracts
    (Marmara University, 2025) Sen, Ali; Servı, Hüseyın; Barak, Timur Hakan; Tekin, Fethullah; Şener, Azize; Marzi, Mahdi; Gülmez, Gizem
    Plants are the significant global interest as alternative treatment sources with their biologically activecompounds. This study compares the chemical composition and the antioxidant, antidiabetic, and antimicrobialproperties of ethanol extracts of G. glabra L. two different varieties from different regions. The phytochemicalcompositions was determined using GC-MS. Additionaly, total phenolic (TPC), flavonoid (TFC) and triterpene (TTC)contents were determined. Glycyrrhizic acid contents were analysed by HPLC. G. glabra var. glandulifera (GF1) showedthe highest antioxidant activity. All extracts had strong antidiabetic effects, besides GF1 showing the highest effect. TheMIC values was determined against 8 bacterial and 1 yeast strain and values ranged from 2.500 to 0.500; 2.500 to 0.714;2.500 to 0.714 for G. glabra var. glabra (GB), GF1, G. glabra var. glandulifera (GF2) respectively. Phytochemical studies haveshown that TPC was 100.60±5.06, 127.90±0.30, 69.01±0.30 mg GAE /g extract; TFC was 80.07±0.15, 25.35±0.0, 16.58±0.31mg KE/g and TTC was 217.30±6.05,172.40±2.17, 126.30±4.50 mg OE/g extract for GB, GF1, GF2, respectively. GF1 inparticular has the highest glycyrrhizic acid content. This study will contribute to the creation of new treatment strategiesand potential therapeutic agents in addition to the use of G. glabra L. in traditional treatments. Our study is also apreliminary study for future studies.
  • Article
    Tsunami Awareness: A Case Study Of Hasköy, Beyoğlu, İstanbul
    (Afet ve Acil Durum Yönetimi Başkanlığı (AFAD), 2025) Taskin, H.; Gunaydin, D.H.; Yücel, G.
    An earthquake-triggered tsunami, originating from seismic activity in seas and oceans, poses a significant threat to coastal settlements within its impact zone. As part of risk reduction efforts, enhancing public awareness of tsunamis is crucial for mitigating potential disaster-related damages. Accordingly, this study emphasizes the importance of tsunami awareness initiatives by assessing the pre-disaster knowledge levels of the community. The study aims to measure the tsunami-related knowledge and awareness levels of residents in a settlement exposed to tsunami hazards. In this qualitative research, data were collected through semi-structured interviews conducted with business owners and employees in a purposively selected settlement. The study was carried out in the Piripaşa neighborhood of the Hasköy district in Istanbul’s Beyoğlu region, specifically within the coastal area parallel to the shoreline of the Golden Horn. Data were obtained from 22 active commercial enterprises out of 50 located along this coastal road. During the interviews, five key questions were posed to assess the respondents’ basic knowledge of tsunami awareness. The questionnaire also included images of tsunami evacuation route signs. The questions covered demographic characteristics, business activity sector, knowledge of tsunami hazards, awareness of the region’s tsunami risk, familiarity with tsunami evacuation procedures, and knowledge of relevant institutions and organizations involved in tsunami preparedness. The findings of the study indicate that the majority of the surveyed enterprises predominantly operate within the service sector. Furthermore, the results reveal a notably low level of awareness among participants regarding tsunami hazards, as well as limited knowledge of appropriate response behaviors during such events. While 50% of participants believe that the region is not at risk of tsunamis, 59% reported being aware of tsunami warning signs, which is a notable observation. Enhancing awareness of tsunami hazards and the region’s tsunami risk level is both essential and a priority. © (2025), (Afet ve Acil Durum Yonetimi Baskanligi (AFAD)). All right reserved.
  • Article
    19. Yüzyıl İstanbul Endüstri Mirasına Palimpsest Kavramı Üzerinden Ontolojik Değerlendirme
    (Atatürk Üniversitesi, 2025) Ural, Ayşe Gülçin
    Eski yazılı parşömen kağıtlarının silinip üzerine yeniden yazılar yazılması, ancak eski yazı izlerinin hala görünüyor olması hali palimpsest olarak tariflenmektedir. Mekân üzerinden bu kavramı incelemek gerekirse; yeniden işlevlendirilen yapılar içinden eski işlevin ve yapım biçiminin izlerini hala görebilmek şeklinde yorumlanabilmektedir. İstanbul gibi büyük tarihe sahip bir kentte, yeniden işlevlendirilmeye ihtiyaç duyan pek çok tarihi yapı bulunmaktadır. Bu yapılar içinde palimpsest kavramının daha net bir şekilde algılanabileceği yapı tipinin endüstri yapıları olduğu düşünülmüştür. Bu nedenle çalışma İstanbul, Avrupa ve Anadolu yakasında bulunan 19. yy. endüstri yapıları ile sınırlandırılmıştır. Çalışmanın amacı ise İstanbul’da bulunan 19. yy. endüstri yapılarının 2024 yılındaki durumlarına göre palimpsest kavramı üzerinden değerlendirme ve sorgulama yapmaktır. Çalışmada veri toplama yöntemi olarak nitel araştırma yöntemlerinden genel tarama modeli, belgesel tarama modeli ve tarihsel tarama modelinden faydalanılmıştır. Kavramsal zemini oluşturmak için genel tarama modeli ile palimpsest kavramına ve mekân ontolojisine dair inceleme yapılmıştır. Belgesel tarama yoluyla, tespit edilen yapıların çeşitli özelliklerine dair veri toplanmıştır. Tarihsel tarama ile ise yapıların yapım yılından itibaren geçirdiği süreç ve 2024 aralık ayında ne durumda olduğuna dair tespit yapmak istenmiştir. Toplanan teknik veriler ve görseller hermenötik yöntem ile değerlendirilmiştir. Çalışmanın sonucunda İstanbul’da bulunan 19. yy. endüstri yapıları içinde 11 adet Avrupa yakasında, 4 adet Anadolu yakasında palimpsest olarak değerlendirilebilecek yapı tespit edilmiştir. Araştırma; İstanbul’da bulunan 19. yy. endüstri yapılarının 2024 yılındaki durumlarını listelemek açısından ve bu yapıları mekânın ontolojisi üzerinden değerlendirilerek palimpsest kavramı ile yorumlamak açısından gerekli görülmüştür.
  • Article
    Relationship Between Resilience, Secondary Traumatic Stress and Work-Related Factors Among Mental Health Professionals
    (Kare Publ, 2025) Dikec, Gul; Tokatlıoglu, Tugba Sahın; Çetinkaya, Saadet; Yasar, Saadet
    Objectives: Resilience is the ability to maintain or rapidly recover mental health under stress. Mental health profes- sionals are often exposed to workplace stress through violence, emotional labor, restrictions, and traumatic stories. Secondary traumatic stress results from being affected by others’ traumatic experiences. Examining the relationship between resilience and secondary traumatic stress among mental health professionals is therefore essential. Methods: This descriptive study was conducted between February and April 2022. Data were collected using the Per- sonal Information Form, the Resilience Scale for Adults, and the Secondary Traumatic Stress Scale. Participants included 212 psychiatric and mental health nurses, 28 psychiatrists, 14 psychologists, and six social workers. Results: A significant positive relationship was found between resilience and secondary traumatic stress. The regres- sion model, including secondary traumatic stress, gender, educational status, willingness to work in mental health, job satisfaction, and unit of work, significantly predicted resilience. Conclusion: Secondary traumatic stress and work-related factors, such as willingness and satisfaction with working in mental health and the unit of work, were found to play an essential role in resilience. Institutional support and supervision may strengthen resilience, while reducing secondary traumatic stress can enhance motivation and well- being. Institutions are recommended to implement strategies that address these factors to improve both resilience and professional effectiveness.
  • Article
    Evaluation of Dietary Habits and Related Parameters in a Group of Inpatients With Mental Disorders
    (Kare Publ, 2025) Dikec, Gul; Ata, Elvan Emıne; Özer, Duygu; Çalışkan, Mahinur Betül; Taliskan, Mahinur Betul
    Objectives: This study aimed to examine the dietary habits and related parameters of individuals with mental disorders. Methods: This study was descriptive and cross-sectional. The sample consisted of 94 individuals hospitalized in the psychiatric clinic of a hospital between June and December 2021. Data were collected using an information form cre- ated by the researchers. Results: Of the participants, 83% were male, and 25.5% had a chronic physical illness. The patients had a diagnosis of mental disorder for an average of 6.07 years. The most common side effect was an increase in appetite (36.4%). Additionally, 76.6% ate within 15 minutes, 93.6% consumed fish once a week or never, and 56.4% never exercised. In- dividuals who consumed home-cooked meals had lower BMI averages than those who consumed fast food. A weakly significant positive correlation was found between BMI and waist circumference averages and the duration of medica- tion use. Individuals with anxiety disorders had lower waist circumference, glucose, and LDL values compared to those with mood disorders. In contrast, individuals with psychotic disorders had significantly lower LDL levels than those diagnosed with mood disorders. Conclusion: Individuals with mental disorders were found to have inadequate and unbalanced nutrition, consuming diets rich in carbohydrates and low in protein, which negatively affected their parameters. Psychiatric nurses should evaluate the dietary habits of patients and provide counseling about healthy nutrition.
  • Article
    Comparison of HLA-G Levels for Cord Blood Derived-MSC and Wharton's Jelly Derived-MSC
    (Walter de Gruyter GmbH, 2025) Abatay Sel, Figen; Erol Bozkurt, Ayse; Karatas, Sule; Suleymanoglu, Mediha; Yasa, Beril; Yasa, Cenk; Savran Oguz, Fatma; Oǧuz, Fatma Savran; Sel, Figen Abatay; Bozkurt, Ayşe Erol
    Objectives: A special group of stem cells with multipotent and immunomodulatory properties are mesenchymal stem cells (MSCs). Many modulatory factors are thought to mediate immunomodulatory properties of MSCs. One of these modulatory factors is thought to be HLA-G, one of human leukocyte antigens (HLA). This study aimed to compare HLA-G levels in both stimulated and unstimulated of peripheral blood mononuclear cell (PBMC) cultures with "cord blood-MSC" (CB-MSC) and "Wharton's jelly-MSC" (WJ-MSC) at different rates and different incubation periods. Methods: WJ-MSCs were obtained by explant method, and CB-MSCs using Ficoll-paque. They were characterized by flow cytometry. MSCs and PBMCs were directly co-cultured for 24 and 72 h at 1:5 and 1:10, respectively. After incubations, the media were collected and HLA-G levels were measured by ELISA. Results: In the unstimulated group, the highest HLA-G level was found in the PBMC:WJ-MSC-72-1:5 group, while the lowest HLA-G level was found in the PBMC:CB-MSC-72-1:5. When 24-1:5 and 72-1:5 groups were examined, the HLA-G level decreased significantly in CB-MSC groups compared to WJ-MSC, while it increased significantly in the 24-1:10 and 72-1:10 groups (p<0.05). In stimulated groups, the highest HLA-G level was observed in the PBMC:CB-MSC-24-1:5. Conclusions: Our study aimed to evaluate the immunomodulatory effect of MSCs via HLA-G molecule. HLA-G levels changed with different incubation times of two different MSC sources. In this study, we suggest that MSCs as a cell therapy, in particular for immune system-related disease, may be a preliminary in vitro approach to evaluate the immunomodulatory effect via HLA-G.
  • Article
    Determination of Post-Earthquake Trauma Level and Investigation of the Relationship with Physical Activity Status
    (Turkish Physiotherapy Association, 2025) Tosun, Anil; Yılmaz, Nergis; Luque, Demet Tekın De Las Penas; Tekin De Las Penas Luque, Demet
    Amaç: Çalışmanın amacı; 06 Şubat 2023’te meydana gelen Pazarcık-Elbistan merkezli depremler sebebiyle kişilerde oluşan travma düzeyinin, kişinin fiziksel aktivite durumu ile ilişkisini incelemektir. Aynı zamanda, kişilerde deprem sonrası ağrı varlığının sorgulanması ve bu durumun travma düzeyi ile ilişkisini ortaya koymaktır. Yöntem: Veriler çevrimiçi olarak Google formları aracılığıyla toplandı, 18-65 yaş arası 388 gönüllü katılımcı (299 kadın, 89 erkek) çalışmaya dahil edildi. Katılımcıların genel özelliklerini belirlemek için “Sosyodemografik Bilgi Formu”, travma düzeyini değerlendirmek için “Deprem Sonrası Travma Düzeyini Belirleme Ölçeği” (DSTDBÖ) ve fiziksel aktivite durumlarını belirlemek için “Uluslararası Fiziksel Aktivite Anketi Kısa Formu” (IPAQ-KF) kullanıldı. Bulgular: Deprem bölgesinde bulunma durumuna göre DSTDBÖ genel puan ortalamaları arasında anlamlı fark saptandı (p<0,001). Deprem bölgesinde bulunan 126 kişinin DSTDBÖ genel puan ortalaması 57,66±19,87 iken, bölgede bulunmayan 262 kişinin ortalaması 49,00±18,49 olarak bulundu. Spearman korelasyon analiziyle deprem bölgesinde olan ve olmayan bireylerin IPAQ-KF toplam puanları, DSTDBÖ alt faktör ve toplam puanları arasındaki ilişki incelenmiş olup sadece “Bilişsel Yapılandırma” alt faktörü ile IPAQ-KF toplam puanları arasında anlamlı bir ilişkiyi yansıtmayan negatif zayıf ilişki bulundu (deprem bölgesinde olanlar için Spearman korelasyon katsayı değeri =-0,18, p=0,042). Ve deprem sonrası ağrı yaşayan bireylerin DSTDBÖ puanları, ağrı yaşamayanlardan daha yüksek olarak saptandı (p=0,000). Sonuç: Bu çalışma ile deprem sonrası travma düzeyinin, fiziksel aktivite ile negatif ilişki gösterdiği belirlendi. İnaktif bireyler daha yüksek travma düzeylerine sahipken, minimal aktif bireylerde travma düzeyleri daha düşük bulundu. Bu bulgular, deprem sonrası fiziksel aktivitenin artırılmasının travma düzeylerini azaltmada etkili bir strateji olabileceğini göstermektedir. Bu alanda daha fazla araştırma, eğitim ve proje çalışmalarının yapılması gerekmektedir.
  • Article
    In Vitro Efficacy of Sumac (Rhus coriaria) Extracts Against Leishmania Tropicana and Leishmania Mexicana: A Preliminary Study from Turkiye
    (Istanbul Univ, 2025) Mete, Ergun; Ozel, Yener; Bardakci, Hilal; Durmuskahya, Cenk; Koseler, Aylin; Kurt, Ozgur
    Objective: Cutaneous leishmaniasis (CL) is a common clinical manifestation of leishmaniasis. Here, the in vitro anti-leishmanial efficacy of sumac extracts was tested for the first time on both Leishmania (L.) tropica and L. mexicana isolates using Rhus (R.) coriaria plant, which was collected in western Anatolia. Materials and Methods: The dried and powdered fruits of R. coriaria were macerated in acetone, ethyl alcohol, and ethyl alcohol-water mixture at room temperature for two days. The pooled extracts were evaporated under reduced pressure and lyophilized form for the study. Isolates of L. tropica and L. mexicana in Acibadem University R&D Laboratory were initially thawed and cultivated in NNN medium. Assessments were made using the haemocytometer and MTT methods at 24 and 48 h, compared with meglumine antimoniate as the control group. Results: For L. tropica, the effective concentration ranges of the extracts and the infusion were found to be 578.13-289.06 pg/mL and 289.06-144.53 pg/mL, respectively. For L. mexicana, the ranges were found to be 289.06-144.53 pg/mL and 144.53-72.27 pg/mL, respectively. It was shown that all extracts of R. coriaria were effective against both L. tropica and L. mexicana in higher doses, compared to meglumine antimoniate. Conclusion: An interesting finding was that higher sumac doses were required to eliminate L. tropica of the Old World, compared to L. mexicana of the New World. In addition, the aqueous alcohol extract showed efficacy that lasted for 48 h in half doses compared to others in L. tropica. Further assessments for both the identification of the active compounds within R. coriaria and their efficacy in vivo are planned.