TR-Dizin İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/9

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  • Article
    Citation - WoS: 4
    Citation - Scopus: 3
    Multidrug Resistance in Pathogens of Community-Acquired Urinary Tract Infections in Turkey: a Multicentre Prospective Observational Study
    (Tubitak Scientific & Technological Research Council Turkey, 2023) Sencan, Irfan; Karabay, Oguz; Altay, Fatma Aybala; Suzuk Yildiz, Serap; Simsek, Husniye; Gozukara, Melih Gaffar; Surme, Serkan; Engin, Derya Öztürk; Cag, Yasemin; Kul, Gülnur; Habip, Zafer; Kaya, Safak; Tasbakan, Meltem
    Background/aim: To have country-wide information about multidrug resistance (MDR) in isolates from community-acquired urinary tract infections (CAUTI) of Turkey, in terms of resistance rates and useful options.Materials and methods: We used a geocode standard, nomenclature of territorial units for statistics (NUTS), and a total of 1588 community-acquired isolates of 20 centres from 12 different NUTS regions between March 2019 and March 2020 were analysed. Results: Of the 1588 culture growths, 1269 (79. 9%) were Escherichia coli and 152 (9.6%) were Klebsiella spp. Male sex, advanced age, and having two or more risk factors showed a statistically significant relation with MDR existence (p < 0.001, p: 0.014, p < 0.001, respectively) that increasing number of risk factors or degree of advancing in age directly affects the number of antibiotic groups detected to have resistance by pathogens. In total, MDR isolates corresponded to 36.1% of our CAUTI samples; MDR existence was 35.7% in E. coli isolates and 57.2% in Klebsiella spp. isolates. Our results did not show an association between resistance or MDR occurrence rates and NUTS regions.Conclusion: The necessity of urine culture in outpatient clinics should be taken into consideration, at least after evaluating risk factors for antibacterial resistance individually. Community-acquired UTIs should be followed up time-and region-dependently. Antibiotic stewardship programmes should be more widely and effectively administrated.
  • Article
    Citation - WoS: 1
    International Cybersecurity Norms and Responsible Cyber Sovereignty
    (Istanbul Univ, Fac Law, 2021) Eldem, Tuba
    Initially envisioned as a free and open communication space between people, free from state regulation and intervention, cyberspace has become a fundamental subject of national and global politics over the last decade. Allegedly state-sponsored cyber operations against Estonia in 2007, Georgia in 2008 and Iran in 2010 played an important role in turning cybersecurity into a national and international security issue. Although the development of cyber diplomacy and international cybersecurity law were left behind the militarization of cyberspace, nevertheless, there have been many international initiatives to adopt international cybersecurity norms in the past decade. Within the framework of the life cycle model of the norms developed by Martha Finnemore and Kathryn Sikkink (1998), this article aims to shed light on the emergence of international cybersecurity norms by focusing on the negotiations held at the First Committee of the United Nations for more than twenty years. The article argues that those negotiations held under the First Committee dealing with disarmament and international security issues indicate the first stage of the formation of international rules related to cyberspace, and the negotiations to be completed under the UN Open-Ended Working Group in 2021 is critical for the transition of international cybersecurity norms from the first to the second stage.