TR-Dizin İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/9
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Article The Current Face of Mosaic Art: Flacking Istanbul Examples(Bursa Uludag University, 2025) Ural, A.G.French artist Ememem is an anonymous artist who started producing his artworks in the city of Lyon in 2016. The unknown street artist brought a contemporary perspective to the art of mosaic by decorating or patching the sidewalks with mosaic art. The term ‘flacking’, which he developed to express the combination of various fields such as upcycling, street art, mosaic art, is becoming increasingly common and attracting the attention of local municipalities. The aim of this study is to discuss the art of flacking, which is a face of mosaic art, which is a very old branch of art, derived from current terms. In terms of scope, examples from Istanbul will be tried to be found and compared with foreign examples. French artist Ememem is an anonymous artist who started producing his artworks in the city of Lyon in 2016. The unknown street artist brought a contemporary perspective to the art of mosaic by decorating or patching the sidewalks with mosaic art. The term ‘flacking’, which he developed to express the combination of various fields such as upcycling, street art, mosaic art, is becoming increasingly common and attracting the attention of local municipalities. The aim of this study is to discuss the art of flacking, which is a face of mosaic art, which is a very old branch of art, derived from current terms. Examples from around the world show how mosaic art can be transformed into impressive and meaningful projects in public spaces. However, it has been seen that modern mosaic trials are still insufficient in our country. It has been determined that for the development of mosaic art, various courses, workshops, contemporary examples to be applied in public spaces and initiatives should be made in order not to lose this valuable art. © (2025), All Rights Reserved.Article Reading Basic Design Principles Through Modern Architectural Structures(Nilay Ozsavas Ulucay, 2023) Yıldırım Coruk, İ.; Coruk, Ipek YildirimBasic design principles are taught within the scope of basic design education in the first-year studios. Basic design education and its content have different dimensions from the education system the student previously received due to its structure and difficulty comprehending because it contains new literature for the student and often has abstract educational content. On the other hand, the students have difficulty perceiving the information acquired in this course and question how they can benefit from it in the following years and professional life. Therefore, the aim of the study is to analyze the basic design principles through modern architectural structures. In the study created by qualitative research method, the data were obtained by analyzing the principles mentioned in the determined examples. These examples were selected among the Bauhaus and later modern buildings by considering the role of the Bauhaus school, where the basic design principles emerged in the spread of modern architecture, and the scope of the study was created. As a result of the study, concrete uses and equivalents of basic design principles were revealed with the determined examples. Thus, data on how students will benefit from basic design principles have been revealed. © 2023, Nilay OZSAVAS ULUCAY. All rights reserved.Article Panax Ginseng Extract Ameliorates Methotrexate-Induced Multi-Organ Damage Via the Regulation of Oxidative Stress(Marmara Univ, 2023) Macit, Caglar; Ede-Pazarbasi, Seren; Yilmaz-karaoglu, Suemeyye; Tunali-Akbay, Tugba; Karakaya-Cimen, Fatma Bedia; Ercan, Feriha; Sener, Goksel; Akbay, Tugba Tunalı-Oxidative damage plays an important role in organ toxicities caused by methotrexate (MTX). This study aimed to determine the antioxidant effects of Panax ginseng (PxG) extract against MTX-induced liver, lung, ileum and kidney damage. Twenty-four Sprague Dawley male rats (weight 250-300 g) were used in the study. The animals were randomly separated into three groups: a) Control, b) MTX-treated (MTX) and c) MTX+PxG-treated (MTX+PxG) groups. MTX was administered intraperitoneally at 20 mg/kg, as a single dose to MTX and MTX+PxG groups. PxG was administered orally at 100 mg/kg to the MTX+PxG group for five days. Saline was given to the control and MTX groups for 5 days. At the end of the experiment, liver, lung, ileum, and kidney samples were obtained. Malondialdehyde (MDA) and glutathione (GSH) levels, superoxide dismutase (SOD), glutathione-S-transferase (GST) and tissue factor (TF) activities were determined in all tissues. In addition, histological examinations were done through light microscopy. GraphPad Prism 5v. was used for statistics, and p<0.05 were considered significant. Administration of MTX caused severe injury in tissues. Findings showed that MDA level, SOD, and GST activities were significantly normalized in the MTX+PxG group compared to the control group. A significant reduction in GSH level observed in the MTX group was reversed with PxG administration In addition, TF activity and total protein levels were found to be impaired in the MTX group, but TF activity was significantly improved in liver and lung tissues and total protein level was significantly reversed in lung and ileum in MTX+PxG group. The results of histological examinations showed that MTX-induced damage was ameliorated with the PxG administration. In conclusion, this study shows that Panax ginseng, thanks to its antioxidant properties, reversed MTX-induced tissue damage and therefore may be beneficial against side effects in patients undergoing chemotherapy.Article Nonviolent Communication in Lifelong Education(Hacettepe Univ, 2023) Baban, Ece; Erdinc, Ece Dogan; Doğan, Ece; Doğan Erdinç, EceIn today's world, the increase of othering and xenophobia with acts of violence, along with the changes that consume resources due to climate changes such as wars, irregular migration movements, famine and thirst, are an important necessity for understanding nonviolent communication and its application in the field of lifelong education. This requirement brought the problem of "adult education" to the agenda and accelerated the studies on the lifelong learning approach. In addition, key messages developed by UNESCO and the European Commission defined the characteristics that the lifelong learning approach should have. Within the scope of the study, the concept of nonviolent communication explained, and the "Make a Gesture Your Opponent" campaign, which includes nonviolent communication training for Turkey Football Federation first league teams, examined. Within the scope of the study, the "Make a Gesture to Your Opponent" campaign was determined as a case study. Accordingly, the official website of the campaign was examined. As a result of the analysis carried out in line with the key messages, the nonviolent communication approach that the "Make a Gesture Your Opponent" project wanted to instill in its participants shows how important education is in all areas of life.Article The Effects Of<i> Panax</I><i> Ginseng</I> on Serum Oxidative Stress Following Bisphenol a Exposure(Istanbul Univ, 2024) Fazalyar, Najiullah; Pazarbasi, Seren Ede; Dorucu, Dogancan; Sener, Goksel; Tunali-Akbay, Tugba; Ede-pazarbasi, SerenObjective: Bisphenol A (BPA) is a toxic compound that causes oxidative stress by disrupting antioxidant enzymes and promoting tissue lipid peroxidation. This study aimed to examine the impacts of BPA on serum oxidative stress in rats and to detect the antioxidant feature of Panax ginseng (PxG) in reducing BPA-induced oxidative stress. Materials and Methods: Wistar Albino rats (250-300 g) were divided into control, control + PxG, BPA, and BPA + PxG groups. 50 mg/kg BPA and 100 mg/g PxG were given for six weeks. Serum total antioxidant and oxidant status, lipid peroxidation, and glutathione levels were determined. Results: BPA administration increased total oxidant status and lipid peroxidation, while PxG administration to the BPA group decreased these parameters. PxG also increased total antioxidant status and glutathione levels compared to the BPA group. Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure.Article Citation - WoS: 3Citation - Scopus: 3Investigation of the Protective and Therapeutic Efficacy of <i>myrtus Communis</I> Extract in Aluminum Chloride and Dgalactose-Induced Alzheimer's Disease in Rats(Marmara Univ, 2022) Yalman, Kiibra; Sen, Ali; Cevik, Ozge; Kadioclu-Yaman, Beril; Ertas, Biiva; Yildiz, Sila; Sener, Goksel; Yaman, Beril Kadıoğlu; Kadioğlu-Yaman, BerilThis study investigated the possible protective and therapeutic effects of Myrtus communis subsp. communis ethanol extract (MC) in aluminum chloride (AlCl3) and D-galactose (D-Gal) induced Alzheimer's disease in rats. MC was orally given to rats as a protective treatment for 90 days and, in other two groups starting from the 60th day MC (100-200 mg/kg) was administered, concomitantly with AlCl3 and D-Gal. Learning and memory functions were evaluated by the behavioral tests. Biological activities of MC treatment were examined in hippocampal tissues by ELISA tests. D-Gal and AlCl3-treated rats showed increased amyloid beta (A ss) and 8-hydroxy-2-deoxyguanosine (8OHdG) levels, acetylcholinesterase activity and decreased neprilysin, Na+-K+ATPase and SOD levels in parallel with a decrease in Novel Object Recognition Test, Morris Water Maze and Passive Avoidance Test scores. On the other hand, MC administration reversed the behavioral impairments and improved learning and memory. Moreover, MC treatment decreased A ss and 8-OHdG levels and acetylcholinesterase activity and increased neprilysin levels, Na+-K+ATPase and SOD levels. Our results suggest that MC has beneficial effects on cognitive and neuronal functions through its anticholinesterase and antioxidant properties.