WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14627/6

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The Acute Effects of Various Dynamic Stretching Exercises on Jump Performance and Range of Motion
(Universidad de Murcia, 2025) Savaan, Mustafa; Pmar, Yeliz; Pmar, Salih
This study aimed to investigate the acute effects of different dynamic stretching (DS) protocols on vertical jump performance and range of motion (ROM). Thirty healthy male participants, with an average age of 23.48 years, body weight of 76.90 kg, and height of 181.87 cm, who had engaged in recreational exercise for at least two years, participated voluntarily. A "cross-controlled randomized" experimental design was utilized to assess four distinct DS protocols: a-DS at 100 bpm for 30", b-DS at 100 bpm for 75" s, c-DS at 150 bpm for 30", and d-DS at 150 bpm for 75". Acute ROM was measured using the Passive Straight Leg Raise Test (PSLR), while jump performance was assessed via countermovement jump (CMJ). Data were analyzed using repeated measures ANOVA and paired samples T-tests with significance set at p<.05. All four DS techniques significantly increased angles measured by PSLR following application (p <.05). CMJ values also showed significant improvements in both groups subjected to the shorter protocols lasting 30"at either tempo (p <.05). Consideration should be given to application duration and tempo when planning DS exercises, as structured warmup routines can enhance flexibility and optimize athletic performance.
Citation - WoS: 38
Appraising Systematic Reviews: a Comprehensive Guide To Ensuring Validity and Reliability
(Frontiers Media Sa, 2023) Shaheen, Nour; Shaheen, Ahmed; Ramadan, Alaa; Hefnawy, Mahmoud Tarek; Ramadan, Abdelraouf; Ibrahim, Ismail A.; Flouty, Oliver
Systematic reviews play a crucial role in evidence-based practices as they consolidate research findings to inform decision-making. However, it is essential to assess the quality of systematic reviews to prevent biased or inaccurate conclusions. This paper underscores the importance of adhering to recognized guidelines, such as the PRISMA statement and Cochrane Handbook. These recommendations advocate for systematic approaches and emphasize the documentation of critical components, including the search strategy and study selection. A thorough evaluation of methodologies, research quality, and overall evidence strength is essential during the appraisal process. Identifying potential sources of bias and review limitations, such as selective reporting or trial heterogeneity, is facilitated by tools like the Cochrane Risk of Bias and the AMSTAR 2 checklist. The assessment of included studies emphasizes formulating clear research questions and employing appropriate search strategies to construct robust reviews. Relevance and bias reduction are ensured through meticulous selection of inclusion and exclusion criteria. Accurate data synthesis, including appropriate data extraction and analysis, is necessary for drawing reliable conclusions. Meta-analysis, a statistical method for aggregating trial findings, improves the precision of treatment impact estimates. Systematic reviews should consider crucial factors such as addressing biases, disclosing conflicts of interest, and acknowledging review and methodological limitations. This paper aims to enhance the reliability of systematic reviews, ultimately improving decision-making in healthcare, public policy, and other domains. It provides academics, practitioners, and policymakers with a comprehensive understanding of the evaluation process, empowering them to make well-informed decisions based on robust data.
Assessment of the Psychometric Properties of the Online Education Student Satisfaction Scale: a Methodological Study
(Springer Publishing Company, 2024) Harmancı Seren, A.K.; Alan, H.; Türkmen, E.; Gungor, S.; Baykal, Ü.
Background and Purpose: Assessing student satisfaction is essential in evaluating the quality of education. The number of valid and reliable tools that measure students’ satisfaction with online education is limited. This methodological study aimed to assess the psychometric properties of the online education student satisfaction scale. Methods: Eleven academicians from the nursing field provided expert opinions on content validity. Separate 25 students evaluated the language clarity of the draft scale. The study sample included 525 third- and fourth-year nursing students. Finally, a group of 30 nursing students different from the sample participated in the test–retest. The study created an item pool based on the recent literature. The researchers calculated the items’ content validity rates and the scale’s content validity index by taking the experts’ opinions. In addition, item–total score correlation analysis, exploratory factor analysis, discrimination analysis, stability test, and internal consistency analysis were performed. Results: An item with a low-correlation value was excluded from the scale. The correlation coefficients of the remaining items were between.536 and.811. In the second round of exploratory factor analysis, a five-factor structure emerged that explained 72.1% of the total variance. In addition, item discrimination, stability, and internal consistency test results ensured that the scale was valid and reliable. Conclusions: The online education student satisfaction scale with five subdimensions containing 28 items is a valid and reliable tool. Researchers, educators, and managers may use it to evaluate students’ satisfaction with online education. © Copyright 2024 Springer Publishing Company, LLC.
Avatar: a Film at the Center of the Feminine Other
(Univ Pittsburgh, Univ Library System, 2025) Dereboyu, Pelin Guregen; Guzel, Ebru; Olaru, Gabriela Oana; Ayberk, Erhan
This study analyzes James Cameron's 2009 film Avatar from the perspective of the feminine other through deconstruction. In the movie, nature and the Na'vi people are depicted as feminine, while modern man and the science, technology, and military power he represents are portrayed as masculine. Although it critiques the colonialist structure of modernity, the film's narrative structure and character portrayals indicate that it reproduces the superiority of Western-centered ideology and the masculine mind. The study analyzes how the film's narrative and character representations implicitly support masculine centrism. The analysis reveals how nature and marginalized cultures are romanticized and presented in the film and how the notion that the feminine can only survive by adopting masculine traits is processed in the subtext. Grounded in a conceptual and theoretical framework, this research focuses on the sustainability of the patriarchal capitalist system and gender politics while critically examining how cinema reconstructs ideological structures through the narratives in the film.
Biopsychosocial-Based Exercise Model for Rheumatic Diseases Via Telerehabilitation: a Case Series With a One Year Follow Up
(Nova Southeastern Univ, 2025) Nacar, Nazli Elif; Karaca, Nur Banu; Bulut, Zeynep Irem; Sari, Erkin Oguz; Bulut, Senem
Purpose: This study aims to examine the sustainability of the biopsychosocial exercise performed by telerehabilitation on individuals with rheumatic disease, with and without supervision, and investigate the effect of the biopsychosocial-based exercise model on biopsychosocial status, general health status, and anxiety-depression levels of individuals. Method: Twenty patients with rheumatic diseases performed a biopsychosocial-based exercise model Cognitive Exercise Therapy Approach via telerehabilitation with physiotherapist-supervised and unsupervised exercises who continued for three sessions per week for 12 months. Outcome measures were Health Assessment Questionnaire, Hospital Anxiety and Depression Scale, and Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire. Patients were assessed at baseline, 3rd, 6th, 9th, and 12th months. Results: There was no significant difference by time for Health Assessment Questionnaire (p=0.512) and Hospital Anxiety and Depression Scale-anxiety and depression scores (p=0.162 and p=0.825, respectively) between the five measures at the one-year followup. Similarly, there is no significant difference in Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire score outcomes by time (p=0.184). Conclusion: In this study a group of rheumatic patients with face-to-face biopsychosocial exercise habits were able to maintain their exercise habits with realtime telerehabilitation with or without supervised during the 1-year follow-up period during the COVID-19 pandemic was shown. Although there was no improvement in the parameters during the pandemic period when social isolation and depression-anxiety disorders increased, the level of recovery which individuals had previously gained was not adversely affected and the healing properties were preserved with the help of telerehabilitation.
Citation - WoS: 2
Citation - Scopus: 4
Comparison of Motorcyclists' Hand Grip Strength and Reaction Time
(Asoc Didactica Andalucia, 2022) Tekin, D.; Tekin, Demet; Agopyan, A.; Terapi ve Rehabilitasyon Bölümü
The purpose of this study was to compare hand grip strength and reaction times in male motorcycle racers grouped according to different ages and the classes of motorcycle used and determine the relation between these characteristics. Sixty-five healthy male motorcycle racers were divided into four groups according to their age and the power of the motorcycles' engine: (Group-1 [G1] = 600CC/23-34 years; Group-2 [G2] = 600-CC/35-48 years; Group-3 [G3] = 1000-CC/23-34 years; Group-4 [G4] = 1000-CC/35-48 years). Then, Nelson's reaction time and maximal hand grip strength were measured for both hands. There were no significant differences between the groups' grip strength (p>0.05). It was found that G1's right-and left-hand reaction time was faster than that of G2, and G1's left-hand reaction time was faster than that of G3 (p<0.05). The right-hand visual reaction time was found to have a negative weak correlation with the left-hand absolute grip strength (r=-0.247, p=0.047), and there was a weak positive correlation between the left-hand visual reaction time and height (r=0.315, p=0.011). G1's right-hand visual reaction time was better than that of G2 (p < 0.001), and G1's visual left-hand reaction time was better than those of G2 (p < 0.034) and G3 (p < 0.011). Although the absolute and relative hand grip strength values did not differ according to the ages and the engine power of the motorcycle used, it was found that the simple reaction time increased with increasing age.
Citation - WoS: 8
Citation - Scopus: 10
Defining and Modeling Risks in Service Supply Chains
(University of Cincinnati, 2021) Karadayi-Usta, S.; Usta, Saliha Karadayı; Serdarasan, S.; Endüstri Mühendisliği Bölümü
Risk management in supply chains is of growing importance and has been studied extensively in manufacturing supply chains. However, risk in service supply chains (SSCs) is largely neglected. Since SSCs are not immune to disruptions, there is a need to study and understand supply chain risks from a service perspective. This paper sets out to identify, define and examine risks in SSCs. Using a systematic literature review, the paper explicitly defines seven risk types associated with SSCs: financial, relationship, demand, operational, service delivery, Information technology (IT), and external risks. To gain a deeper understanding of these risks and their consequences, a structural model of the relationships among them was developed using ISM and MICMAC. This study helps us to identify and understand all the risks that need to be assessed in SSCs, which in turn would lead to enhanced risk management and business sustainability. © 2021 University of Cincinnati. All rights reserved.
Citation - WoS: 1
Citation - Scopus: 1
Design and Development of a New Tactile Stimulator
(Ieee, 2019) Levent, Vecdi Emre; Levent, Vecdi Emre; Aydin, Nizamettin; Bilgisayar Mühendisliği Bölümü
We have designed and implement a tactile stimulator to obtain information from the central nervous system. Our system consists of two main components. The first one is tactile stimulator, which was designed to stimulate index and middle finger tips, stimulating mechanoreceptors according to the test protocol. Second one is a personal computer running a desktop software for the implementation of test protocols. The flow is as follows; the subjects are asked the question of the test protocol through the personal computer. The parameters are then transmitted to the embedded board on the machine. The embedded board drives step motors to apply the relevant test parameters. The desktop software expects the individual to answer the question using the right or the left mouse button of the computer mouse. After answering the relevant question, the test proceeds to the next step. According to the test protocol, the stimulation process of the mechanoreceptors located at the index and middle finger tips must start and terminate at the same time. From this perspective, the embedded board with 3 18F46K22 PIC microcontrollers produces 2 square wave signals with different frequencies and amplitudes at the same time. The embedded system card developed with the PIC microcontroller is also developed with FPGA. The system has also been tested on 24 blue and white collar employees and a significant result has been obtained.
Determining the Injury Risk Levels of Kyorugi and Poomsae Taekwondo Athletes and Comparing Them With Selected Athletic Performance Parameters
(Stowarzyszenie Idokan Polska-Idokan Poland Assoc, 2025) Ergin, Ceren z.; Pinar, Yeliz; Sani, Fatih; Cumbur, Cansel; Ramazanoglu, Nusret
Background. Different disciplines within the same sport can lead to varying injury risks and performance requirements due to differences in energy systems, techniques, and competition rules. Problem and aim. This study assesses and compares injury risk levels among taekwondo athletes in the kyorugi and poomsae disciplines alongside selected athletic performance parameters. Material and Method. The study included 10 women (22 +/- 2.37 years) and 10 men (22 +/- 1.25 years) from the kyorugi discipline, and 10 women (19.4 +/- 2.55 years) and 10 men (18.8 +/- 3.29 years) from poomsae. All participants had competed in licensed elite-level competitions for at least 4 years. Injury risk and performance were evaluated using the Y balance test (YBT), reactive strength index (RSI), and functional movement screen (FMS). Results. Significant differences were found between male kyorugi and poomsae athletes in rotary stability (p=0.042), dominant leg Y balance (p=0.012), and composite scores (p=0.012). For female athletes, differences in dominant leg Y balance (p=0.049), anterior reach (p=0.027), RSI (p=0.001), and jump height (p=0.001) were noted. Female poomsae athletes had RSI values below normative standards. According to the YBT, the male poomsae group had the lowest number of athletes at risk of injury, whereas the female kyorugi group had the highest. Conclusions. Generally, taekwondo athletes displayed low injury risks based on FMS and YBT values, with moderate to low RSI risk levels. Increased reactive strength may correlate with higher injury risk. Female poomsae athletes should work to improve RSI scores, while kyorugi athletes should focus on strategies to address asymmetry-related injuries.
Determining the Type 2 Diabetes Risks and Healthy Lifestyle Behaviors of First Year University Students
(Dokuz Eylul Univ inst Health Sciences, 2022) Eroglu, Nermin; Eroğlu, Nermin; Temiz, Gamze; Hemşirelik Bölümü
Introduction: The present study was planned and carried out as a descriptive and cross-sectional study for determining the Type 2 diabetes risks and healthy lifestyle behaviors of first year university students. Material and Methods: The study was carried with 185 students at a foundation university in Istanbul during the dates of November-December 2019. The data were acquired online via Student Information Form, Type 2 Diabetes Questionnaire (FINDRISK) and Healthy Lifestyle Behaviors Scale. Results: The mean age of the students in the study was 19.79 +/- 2.47 years, 53.5 % (n=99) were male, 29.7 % (n=55 previously graduated from another university, 62.1 % (n=115) were students and it was determined that 50.3 % (n=93) had diabetic relatives. It was observed when the diabetes risk status was examined for all participants that they are in the low risk group due to a FINDRISK total score of <7. Conclusion: The study results emphasize the importance of determining the risk for university students to be diabetic in the next decade, putting forth the individuals with high risk and moving onto the next stage for diagnosis. In addition, it has been determined that the level of knowledge of students may have a positive impact on their healthy lifestyle behaviors.
Determining the Type 2 Diabetes Risks and Healthy Lifestyle Behaviors of First Year University Students (Vol 6, Pg 420, 2022)
(Dokuz Eylul Univ inst Health Sciences, 2023) Eroglu, Nermin; Temiz, Gamze
Citation - WoS: 1
Citation - Scopus: 1
Do We Learn To Internalize Stigma From Our Parents? Comparison of Internalized Stigmatization in Adolescents Diagnosed With Adhd and Their Parents
(Mdpi, 2022) Dikeç, Gül; Bilac, Oznur; Kardelen, Cansin; Sapmaz, Sermin Yalin; Hemşirelik Bölümü
This study compared internalized stigmatization levels of adolescents diagnosed with attention deficit and hyperactivity disorder (ADHD) with those of their parents. The study's data were collected from 107 adolescents diagnosed with ADHD and their parents between July 2020 and March 2021. The adolescents were followed up in the child and adolescent psychiatry outpatient clinic of a university hospital in western Turkey. The information forms for adolescents and parents, the Internalized Stigma of Mental Illness Scale-Adolescent Form (ISMI-AF) and the Parental Internalized Stigma of Mental Illness Scale (PISMI), were used to collect the data. There was no statistically significant difference between the total scores of internalized stigma and subscale mean scores of the adolescents and their parents (p > 0.05); only the subscale scores for stereotype endorsement were found to be significantly different (p < 0.05). PISMI scores affected ISMI-AF scores, which can be interpreted as parents' perspectives and attitudes toward stigmatization affecting adolescents. For ADHD, whose frequency is increasing daily, intervention studies should be conducted to reduce adolescents' and parents' internalized stigma and to enhance the educational outcomes of adolescents.
Dodder (Cuscuta Sp.) Extract Prevents Cognitive Deficits in a Rat Model of Hepatic Encephalopathy
(Kare Publ, 2024) Albayrak, Omercan; Hatipoglu, Bilge Nur; Ozbeyli, Dilek; Sen, Ali; Koyuncuoglu, Turkan; Cevik, Ozge; Sener, Goksel
OBJECTIVE: In our study, the protective effect of dodder plant extract against encephalopathy induced by cholestatic liver disease model was investigated. METHODS: Spraque Dawley rats were used in the study. For the cholestatic liver disease model, the bile duct ligation (BDL) was applied. The groups were determined as control, Cuscuta sp. (CUS), BDL and BDL + CUS. Double ligation was performed in the bile duct in the BDL groups. For the applications, saline (SF) was administered to the control and BDL groups for 28 days while 250 mg/ kg of Cuscuta sp. extract was given by oral gavage to the CUS and BDL + CUS groups. At the end of the experiment, cognitive evaluations were made by applying new object recognition and Morris water maze tests. After these tests, blood-brain barrier (BBB) measurements were made in half of the groups. In the other half of the groups, brain tissue samples were taken by decapitation and transforming growth factor-beta (TGF-beta), 8-hydroxydeoxyguanosine (8-OHdG) and sodium-potassium adenosine triphosphatase (Na+/K+-ATPase) measurements were made in the tissues. Histological examinations of the tissues were also performed. RESULTS: Cognitive performance was low, and BBB permeability was found to be increased in the group with bile duct ligation. In addition, TGF-beta and 8-OHdG levels were increased in tissues, while Na+/K+-ATPase enzyme activity was suppressed. Treatment with Cuscuta sp. increased cognitive performance and decreased BBB permeability. Other biochemical parameters examined were significantly (p<0.05-0.001) reversed and supported by histological findings. CONCLUSION: Our findings in the study suggest that dodder plant may be beneficial for the protection of cognitive performance and brain tissue in encephalopathy caused by cholestasis.
The Effect of Neck Mobilization Vs. Combined Neck and Lumbar Mobilization on Pain and Range of Motion in People With Cervical Disc Herniation: a Randomized Controlled Study
(Elsevier, 2025) Ozdincler, Arzu; Aktas, Dogan; Reyhanioglu, Duygu Aktar; Ozturk, Basar
Background: To assess the effectiveness of Kaltenborn-Evjenth Orthopedic Manual Therapy (KEOMT) applied to cervical-only mobilization versus both lumbar and cervical regions on pain intensity and range of motion (ROM) in individuals with cervical disc herniation. Methods: Thirty-three participants were enrolled in the study. The patients were randomly assigned to two groups. Group A received cervical-only KEOMT, while Group B received combined lumbar and cervical KEOMT. Interventions were administered three times a week for four weeks. Pain was measured using the Visual Analog Scale (VAS), ROM was assessed for flexion and lateral flexion, and Neck Pain and Disability Index (NPDI) and Short-Form 36 Health Survey (SF-36) were used for evaluation. Results: In intra-group measurements, a statistically significant difference was observed in all parameters of pain, ROM, disability, and quality of life for the mobilization methods applied in both groups (p < 0.05). Group B demonstrated significantly greater improvements in ROM/flexion, pain, and disability outcomes compared to Group A in inter-group measurements (p < 0.05). Physical and emotional sub-groups of quality of life measures also favored Group B in intergroup analysis (p < 0.05). However, the power values for ROM and quality of life parameters were found to be low. Conclusions: The cervical plus lumbar KEOMT technique is more effective than cervical-only mobilization in improving pain and disability. However, low power values for ROM and quality of life suggest these results may lack clinical significance, warranting further research.
The Effect of Vitamin D and Paricalcitol on Protein Disulfide Isomerase
(Marmara Univ, Fac Pharmacy, 2024) Koksal, Muhammed Murat; Sekerler, Turgut; Sener, Azize
Protein disulfide isomerase (PDI), a multifunctional protein plays an important role as oxidoreductase, isomerase and chaperone in the cell. Prior studies have identified PDI is highly expressed in many different cancer types and presented as a new potential target for cancer treatment. Here, we investigated vitamin D and its analogue paricalcitol in silico interaction of the human PDI and inhibition of PDI reductase activity in vitro. We observed a non-covalent mechanism where the main skeleton of the vitamin D3 and paricalcitol structure is located at the hydrophobic site in the b' domain of PDI and forms a hydrogen bond with a residue (His138) in this domain. They also form multiple weak hydrophobic interactions with various chemical groups of the b' subunit. For the first time, we demonstrate that 1,25dihydroxyvitamin D3 (1 alpha,25(OH)2 vitamin D3) and paricalcitol inhibit the PDI reductase activity in vitro and their IC50 values are 20.79 +/- 1.43 nmol/L and 32.82 +/- 3.15 nmol/L respectively. The two compounds can also block the denitrosation activity of PDI.
Citation - Scopus: 1
The Effect of Whey Proteins on the Brain and Small Intestine Nitric Oxide Levels: Protein Profiles in Methotrexate-Induced Oxidative Stress
(Istanbul Univ, 2022) Yılmaz Karaoğlu, Sümeyye; Tufan, Elif; Sivas, Guzin Goksun; Gokmen, Begum Gurel; Dursun, Ercan; Ozbeyli, Dilek; Tunali-Akbay, Tugba; Eczane Hizmetleri Bölümü
Objectives: The aim of this study was to determine the effects of whey proteins on methotrexate (MTX)-induced brain and small intestine damage. Materials and Methods: 30 Sprague Dawley rats (200-300 g) were divided into four groups: Control, control + whey, MTX, and MTX+whey. MTX was administered at 20 mg/kg (single dose) intraperitoneally to the MTX group rats, and 2 mg/kg of whey protein were administered by oral gavage for 10 days to the whey groups. Lipid peroxidation, glutathione, and nitric oxide (NO) levels, as well as glutathione-Stransferase and superoxide dismutase activities were measured in the brain and small intestine. SDS-polyacrylamide gel electrophoresis of the brain and intestine tissues were also carried out. Results: While MTX treatment caused oxidative damage in the brain and small intestine, whey protein administration ameliorated MTXinduced oxidative stress. MTX administration did not change the brain's NO level, while an increase in intestinal NO level was detected. Conclusion: MTX induced oxidative stress in the brain and small intestine changed the protein metabolism in these tissues regardless of reduced food intake. Consecutive 10-day administration of whey proteins has shown its therapeutic effect on MTX-induced brain and small intestine oxidative damage.
The Effects of Pelvic Floor Muscle Training Applied Via Telerehabilitation During the Postpartum Period: a Randomized Controlled Study
(Mary Ann Liebert, inc, 2025) Razak Ozdincler, Arzu; Korkmaz Dayican, Damla; Ozyurek, Burcin
Purpose: To examine the short- and medium-term effects of pelvic floor muscle training (PFMT) applied via telerehabilitation (TR) on pelvic floor muscle function, pelvic floor symptoms, and quality of life. Methods: Fifty-eight women between the ages of 18 and 35 who were between 6 and 8 weeks postpartum were included. The participants were randomized into the PFMT applied via TR (TR-PFMT) group or the supervised PFMT (S-PFMT) group. The PFMT was performed for 8 weeks, 2 days a week, and 45-50 min a day. The participants' pelvic floor muscle function, pelvic floor symptoms, and quality of life were evaluated with the superficial electromyography, the Pelvic Floor Distress Inventory-20 (PFDI-20), and the Pelvic Floor Impact Questionnaire-7, respectively. Results: Phasic, tonic, and endurance activities of the pelvic floor muscles were significantly higher in both groups immediately after and 8 weeks after the exercise program (all p < 0.05). In addition, total PFDI-20 and all subscales' scores decreased significantly in the TR-PFMT group (all p < 0.05). In the S-PFMT group, total PFDI-20 (p = 0.012) and Urinary Distress Inventory-6 (p = 0.012) scores improved significantly. A significant difference was found between the groups in favor of the TR-PFMT group in terms of total PFDI-20 (p = 0.024; p = 0.024) and Urinary Distress Inventory-6 (p = 0.033; p = 0.040) scores immediately after and 8 weeks after the exercise program. Conclusions: TR-PFMT and S-PFMT improved women's pelvic floor muscle function, pelvic floor symptoms, and quality of life in the short and medium term. Improvement in urinary symptoms was greater after TR-PFMT. TR-PFMT should be considered for postpartum women.
The Effects Of Panax Ginseng on Serum Oxidative Stress Following Bisphenol a Exposure
(Istanbul Univ, 2024) Ede Pazarbaşı, Seren; Şener, Göksel; Dorucu, Dogancan; Sener, Goksel; Tunali-Akbay, Tugba; Eczane Hizmetleri Bölümü; Eczacılık Meslek Bilimleri Bölümü
Objective: Bisphenol A (BPA) is a toxic compound that causes oxidative stress by disrupting antioxidant enzymes and promoting tissue lipid peroxidation. This study aimed to examine the impacts of BPA on serum oxidative stress in rats and to detect the antioxidant feature of Panax ginseng (PxG) in reducing BPA-induced oxidative stress. Materials and Methods: Wistar Albino rats (250-300 g) were divided into control, control + PxG, BPA, and BPA + PxG groups. 50 mg/kg BPA and 100 mg/g PxG were given for six weeks. Serum total antioxidant and oxidant status, lipid peroxidation, and glutathione levels were determined. Results: BPA administration increased total oxidant status and lipid peroxidation, while PxG administration to the BPA group decreased these parameters. PxG also increased total antioxidant status and glutathione levels compared to the BPA group. Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure.
Empowering a Mother of Children With Autism: a Case Report on the Impact of Tele-Occupational Performance Coaching on Parent-Child Relationships, Maternal Self-Efficacy, and Occupational Performance
(Routledge Journals, Taylor & Francis Ltd, 2025) Bektas, Selen Aydoner; Bumin, Gonca
This case report aimed at tele-occupational performance coaching to empower the mother of a child with autism spectrum disorder by enhancing occupational performance, parent-child relationships, and maternal self-efficacy. Over 8 weeks, the intervention addressed goals collaboratively identified by the mother, including self-care, productivity, and leisure-related tasks. Results revealed clinically significant improvements, with a two-point increase in Canadian Occupational Performance Measure scores for both performance and satisfaction. Significant score increases were also obtained on the Parent-Child Relationship Scale and the Early Intervention Parenting Self-Efficacy Scale. The findings underscore the effectiveness of tele-occupational performance coaching in enhancing family dynamics and parental capabilities while emphasizing the potential of telehealth as a scalable and accessible modality for delivering family-centered occupational therapy. Future research should expand on these findings by incorporating diverse populations and assessing long-term outcomes.
Citation - Scopus: 1
Ethanolic Extract of Cotinus Coggygria Leaves Attenuates Crystalluria and Kidney Damage in Ethylene Glycol-Induced Urolithiasis in Rats
(Kare Publishing, 2023) Gumru, S.; Şener, Göksel; Ozgur, G.; Ertas, B.; Sen, A.; Eker, P.; Sener, T.E.; Sener, G.; Eczacılık Meslek Bilimleri Bölümü
OBJECTIVE: Nephrolithiasis is a common cause of kidney insufficiency. Nephrolithiasis is proven to be the result of various biochemical and inflammatory processes that result in crystal formation and subsequent aggregation. Cotinus coggygria L. (CCog) is a plant extract which has been used as a Turkish remedy for kidney stones. With this study, we planned to evaluate the effects of CCog extract in ethylene glycol (EG)-induced nephrolithiasis model in rats. METHODS: The study group comprised 32 Wistar albino rats which were divided into Control (C), EG, CCog Prophylaxis (CC+EG+CC), and CCog Treatment (EG+CC) groups. Stone formation was induced by adding EG (0.75%) into rat’s drinking water. Normal drinking water was given to Control group for 8 weeks. Throughout the study period of 8 weeks, EG group was given only EG (0.75%) and CC+EG+CC group was given both EG and CCog. In EG+CC group, EG (0.75%) was given for 8 weeks whereas CCog was given for the past 4 weeks. After the 8th week, 24-h urine samples were collected. Rats were then sacrificed and kidney tissue samples were harvested. RESULTS: Metabolites (calcium, citrate) and creatinine in 24 h urine samples were decreased in CC+EG+CC and EG+CC groups. While hyperoxaluria was observed in the EG group, oxalate levels were similar to control levels in the P-CCog and C-CCog groups. The N-acetyl-β-glucosaminidase and myeloperoxidase activities were both increased in EG group and these parameters were significantly decreased on CCog treatment. CONCLUSION: We can conclude that C. coggygria extract can have beneficial effect on lowering concentration of stone-forming metabolites in urine and consequently protect renal tissues from damage due to nephrolithiasis. C. coggygria extract can be considered as a potential prophylactic and therapeutic option in high-risk stone formers. Furthermore, our data confirm ethnobotanical use of CC against nephrolithiasis. © 2023 by Istanbul Provincial Directorate of Health.

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