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Panax Ginseng Extract Ameliorates Methotrexate-Induced Multi-Organ Damage Via the Regulation of Oxidative Stress
(Marmara Univ, 2023) Macit, Caglar; Ede-Pazarbasi, Seren; Yilmaz-karaoglu, Suemeyye; Tunali-Akbay, Tugba; Karakaya-Cimen, Fatma Bedia; Ercan, Feriha; Sener, Goksel
Oxidative damage plays an important role in organ toxicities caused by methotrexate (MTX). This study aimed to determine the antioxidant effects of Panax ginseng (PxG) extract against MTX-induced liver, lung, ileum and kidney damage. Twenty-four Sprague Dawley male rats (weight 250-300 g) were used in the study. The animals were randomly separated into three groups: a) Control, b) MTX-treated (MTX) and c) MTX+PxG-treated (MTX+PxG) groups. MTX was administered intraperitoneally at 20 mg/kg, as a single dose to MTX and MTX+PxG groups. PxG was administered orally at 100 mg/kg to the MTX+PxG group for five days. Saline was given to the control and MTX groups for 5 days. At the end of the experiment, liver, lung, ileum, and kidney samples were obtained. Malondialdehyde (MDA) and glutathione (GSH) levels, superoxide dismutase (SOD), glutathione-S-transferase (GST) and tissue factor (TF) activities were determined in all tissues. In addition, histological examinations were done through light microscopy. GraphPad Prism 5v. was used for statistics, and p<0.05 were considered significant. Administration of MTX caused severe injury in tissues. Findings showed that MDA level, SOD, and GST activities were significantly normalized in the MTX+PxG group compared to the control group. A significant reduction in GSH level observed in the MTX group was reversed with PxG administration In addition, TF activity and total protein levels were found to be impaired in the MTX group, but TF activity was significantly improved in liver and lung tissues and total protein level was significantly reversed in lung and ileum in MTX+PxG group. The results of histological examinations showed that MTX-induced damage was ameliorated with the PxG administration. In conclusion, this study shows that Panax ginseng, thanks to its antioxidant properties, reversed MTX-induced tissue damage and therefore may be beneficial against side effects in patients undergoing chemotherapy.
Citation - Scopus: 1
Cold Chain Logistics Firm Selection by Using Ahp-Vikor Integrated Method and a Case Study in Food Industry
(Springer Science and Business Media Deutschland GmbH, 2020) Buyukselcuk, E.C.
With the Industry 4.0, a new trend has started for all sectors and enterprises have entered into a period of intense working and investment to turn into intelligent systems. Cold chain logistics also has the same trend, and companies have pushed the button to be involved in this process. Due to changing lifestyles and generally decreasing prices, the world market for perishable products such as processed foods and cooled products is growing. Cold chain transportation is an important issue in basic food and health product logistics to prevent the growth of harmful microorganisms and to ensure that the products remain intact. In this study, it is aimed to determine the right cold chain logistics firm for company EDB that is a small and medium-sized enterprise (SME) operating in the food industry. Firstly, the selection criteria are defined according to the literature survey and expert views. AHP approach has been used to calculate the weight of them. After the determination of weight of criteria, VIKOR approach has been used to identify the best cold chain logistics firm for company EDB. The results were obtained by using Expert Choice 11.0 and Excel calculator finally the best one has been determined. © 2020, Springer Nature Switzerland AG.
Evaluation of the Neuroprotective Effects of Korean Ginseng Root Extract in an Experimental Model of Multiple Sclerosis
(Marmara Univ, Fac Medicine, 2025) Donmez, Muhammet Oguzhan; Sener, Goksel; Akbay, Tugba Tunali; Sivas, Guzin Goksun; Akakin, Dilek; Unlu, Hilal; Goren, Mehmet Zafer
Objective: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterised by demyelination. The aim of this study was to evaluate the neuroprotective effects of Korean ginseng root extract (KGE) using a cuprizone-induced demyelination model. Materials and Methods: C57BL/6 mice were divided into control, demyelination and remyelination groups and each group was treated with KGE. Demyelination was induced with 0.2% cuprizone in the diet for four weeks. KGE (100 mg/kg) was administered by gavage during or after the cuprizone exposure. Body weight, food and water intake, and motor performance parameters were investigated. In addition, glutathione (GSH), glutathione-S-transferase (GST), superoxide dismutase (SOD) malondialdehyde (MDA), oligodendrocyte transcription factor-2 (OLIG2) and myelin basic protein (MBP) levels were measured in brain samples, while MBP and glial fibrillary acidic protein (GFAP) expression was assessed by immunohistochemistry and myelin status was examined using Luxol Fast Blue staining. Results: Korean ginseng root extract prevented myelin loss, promoted remyelination, and improved motor performance. It reduced oxidative stress by increasing GSH, GST, and SOD levels while decreasing MDA. KGE also suppressed demyelination by reducing astrogliosis and restoring OLIG2 and MBP levels. Conclusion: Korean ginseng root extract exhibits neuroprotective properties during demyelination and promotes remyelination, highlighting its therapeutic potential for MS.
Citation - Scopus: 1
Factors in Bread Preference: a Cross-Sectional Study of the Comparison of Anthropometric Measurements and Macronutrient Differences According To Bread Type Preferences
(Ethiopian Public Health Association, 2022) Ilktac, H.Y.; Garipagaoglu, M.
Background: Bread is one of the most consumed foods by humankind throughout history. It is important to evaluate the factors affecting the food preferences of individuals and to examine the effect of frequently consumed food on anthropometric measurements and daily energy and macronutrient intake in order to improve public health and develop nutrition policies of society. Objective: The aim of the current study was two-fold: (1) to determine the factors affecting the bread type preferences of individuals (2) to compare anthropometric measurements and macronutrient differences according to bread type preferences. Methods: The study was conducted cross-sectional from January to October 2018 with randomly selected 1554 volunteer individuals aged between 18-65 years in Istanbul Province of Turkey. The data of the study were collected through a questionnaire form applied by the face-to-face interview method. Demographic information, anthropometric measurements, the most consumed bread types, and dietary records were examined in the questionnaire form. Results: It was determined that the preference for white bread was high (%66.3). White bread and whole-grain bread were consumed 159.4±94 g/day and 131.2±89.2 g/day, respectively. BMI and waist circumference were lower, while the difference was not significant. It was determined that the group who preferred whole-grain bread had fewer carbohydrates, higher fiber, higher protein, higher fat, higher saturated fat, and higher cholesterol intakes in their daily diets. Women, having high education status and old-age popularity increased the preference of whole-grain bread 1.73, 3.39, and 1.03 times compared to the preference of white bread (p<0.001). Conclusion: It has been determined that white bread is preferred more in society. Bread type preference was not associated with anthropometric measurements. It has been determined that the distribution of daily macronutrients of individuals who prefer whole-grain bread is more unbalanced. It was found that gender, educational status, and age were the factors affecting the preference of bread type © 2022, Ethiopian Journal of Health Development.All Rights Reserved.
Forty Years of Event Graphs in Research and Education
(Institute of Electrical and Electronics Engineers Inc., 2023) Gunal, M.M.; Osais, Y.I.; Schruben, L.; Wagner, G.; Yücesan, E.
Forty years ago, in 1983, Lee Schruben proposed the Event Graph formalism and modeling language, subsequently defining the paradigm of Event-Based Simulation, in a precise way, which had been pioneered 20 years before by SIMSCRIPT. The purpose of this panel is for a group of Event Graph researchers both from Operations Research and Computer Science, including the inventor of Event Graphs and one of his former PhD students who has made essential contributions to their theory, to discuss their views on the history and potential of Event Graph modeling and simulation. In particular, the adoption of Event Graphs as a discrete process modeling language in Discrete Event Simulation and in Computer Science, and their potential as a foundation for the entire field of Discrete Event Simulation and for the fields of process modeling and AI in Computer Science is debated. © 2023 IEEE.
Relationship Between Resilience, Secondary Traumatic Stress and Work-Related Factors Among Mental Health Professionals
(Kare Publ, 2025) Dikec, Gul; Tokatlıoglu, Tugba Sahın; Çetinkaya, Saadet
Objectives: Resilience is the ability to maintain or rapidly recover mental health under stress. Mental health profes- sionals are often exposed to workplace stress through violence, emotional labor, restrictions, and traumatic stories. Secondary traumatic stress results from being affected by others’ traumatic experiences. Examining the relationship between resilience and secondary traumatic stress among mental health professionals is therefore essential. Methods: This descriptive study was conducted between February and April 2022. Data were collected using the Per- sonal Information Form, the Resilience Scale for Adults, and the Secondary Traumatic Stress Scale. Participants included 212 psychiatric and mental health nurses, 28 psychiatrists, 14 psychologists, and six social workers. Results: A significant positive relationship was found between resilience and secondary traumatic stress. The regres- sion model, including secondary traumatic stress, gender, educational status, willingness to work in mental health, job satisfaction, and unit of work, significantly predicted resilience. Conclusion: Secondary traumatic stress and work-related factors, such as willingness and satisfaction with working in mental health and the unit of work, were found to play an essential role in resilience. Institutional support and supervision may strengthen resilience, while reducing secondary traumatic stress can enhance motivation and well- being. Institutions are recommended to implement strategies that address these factors to improve both resilience and professional effectiveness.
Positioning School Readiness as Ecological Fit: The School Readiness Ecological Approach (SERA) for Occupational Therapy and Education
(Routledge Journals, Taylor & Francis Ltd, 2026) Aydoner Bektas, Selen
Traditional perspectives on school readiness have emphasized child-level competencies such as cognitive, language, and behavioral skills. While important, the narrow focus overlooks the ecological systems - families, teachers, and communities - that shape children's adaptation to school. The participation-oriented perspective of occupational therapy has also been largely absent from the discourse. The School Readiness Ecological Approach (SERA) reframes school readiness as a matter of ecological fit rather than merely a set of children's skills. Based on Bronfenbrenner's ecological systems theory and the Person - Environment - Occupation model, SERA conceptualizes readiness as the outcome of dynamic exchanges between children, families, educators, schools, and policy environments. SERA addresses key gaps by: (1) shifting focus from isolated child attributes to participation in real-life contexts; (2) integrating occupational therapy's holistic perspective into readiness; and (3) providing a multi-level framework to guide research, practice, and policy. SERA emphasizes four domains - child, family, educational environment, and community - as interconnected contributors to school readiness trajectories. As a conceptual bridge across education, health, and social systems, SERA will broaden theoretical scope, foster interdisciplinary collaboration, and promote inclusive, and sustainable strategies. Reconceptualizing school readiness as ecological fit will help move beyond deficit-based views and support more equitable and effective school transitions.
The Raid in the Editorial Office of the Turkish Newspaper Tan, 1945, and Its Impact on the State of Soviet-Turkish and Us Turkish Relations in the Post-Wwii Period
(Peoples Friendship Univ Russia, 2020) Sivis, Efe
The author examines the demonstrations carried out by university students in Istanbul on December 4, 1945 and the raid on the printing operations of the pro-Soviet 7an newspaper, known as the Tan Raid, in light of U.S. State Department documents, namely the related files in National Archives Records Administration. The influence of the Tan Raid on Turkey's international relations is discussed in the context of Turkish-American and Turkish-Soviet relations. The Raid is regarded as a significant incident since it coincides with the post WW2 period when Turkey's relations with the Soviet Union had already deteriorated due to Moscow's demands to revise the Montreux Convention by 19th of March 1945. Furthermore, Turkish-American diplomatic contacts in the aftermath of the Raid show Washington's perspective on policy towards Soviet Union, as U.S. officials advised a moderate line to their Turkish counterparts. On the other hand, preparations for the Raid seem highly controversial since Turkish government officials did not strongly condemn the event and the police did not intervene against the protestors despite of their violent actions towards Tan and some left leaning bookstores. The slogans during the demonstration show its anti-Soviet character, which Ankara denied in order to decrease tensions with the Soviets by arguing that it was Tan's owner, the Sertel couple to whom the anger was directed, not the Soviet Union. The intelligence obtained by diplomats at the U.S. Embassy in Ankara, the meetings they conducted with Turkish politicians, their conclusions regarding the process leading up to the raid, and their opinions on Turkish-Soviet relations provide the background for the analysis.
The Effects Of Panax Ginseng on Serum Oxidative Stress Following Bisphenol a Exposure
(Istanbul Univ, 2024) Fazalyar, Najiullah; Pazarbasi, Seren Ede; Dorucu, Dogancan; Sener, Goksel; Tunali-Akbay, Tugba
Objective: Bisphenol A (BPA) is a toxic compound that causes oxidative stress by disrupting antioxidant enzymes and promoting tissue lipid peroxidation. This study aimed to examine the impacts of BPA on serum oxidative stress in rats and to detect the antioxidant feature of Panax ginseng (PxG) in reducing BPA-induced oxidative stress. Materials and Methods: Wistar Albino rats (250-300 g) were divided into control, control + PxG, BPA, and BPA + PxG groups. 50 mg/kg BPA and 100 mg/g PxG were given for six weeks. Serum total antioxidant and oxidant status, lipid peroxidation, and glutathione levels were determined. Results: BPA administration increased total oxidant status and lipid peroxidation, while PxG administration to the BPA group decreased these parameters. PxG also increased total antioxidant status and glutathione levels compared to the BPA group. Conclusion: BPA was seen to cause an increase in oxidative parameters and PxG administration to restore the oxidative stress that was generated after BPA exposure, suggesting that this may help to prevent the adverse effects caused by BPA exposure.
Citation - WoS: 3
Citation - Scopus: 4
Association Between Carbohydrate Quality Index and Dietary Patterns, Sleep Quality, Anxiety Level, and Depression Symptoms: a Cross-Sectional Study
(Soc Chilena Nutricion, Bromatologia & Toxicologia, 2022) Yuksel, Aysun; Yilmaz-Onal, Hulya; Basturk, Berrak; Yalcin, Bahar
Aim: This study was conducted to determine the relationship between carbohydrate quality and sleep quality, depression, anxiety, stress and anthropometric measurements. Methods: The carbohydrate quality was calculated using the total fiber intake, ratio of whole grains to total grains, the ratio of solid carbohydrates to total carbohydrates, and the glycemic index. Sleep status was determined using the Pittsburgh Sleep Quality Index (PSQI) and nutritional status was determined by taking a 1-day food consumption record and food consumption frequency. Results: It was found that 20% of the participants with the highest carbohydrate quality had the highest sleep quality and the lowest body mass index. Conclusion: Adults should be informed that the quality of carbohydrates that they consume, was associated with better sleep quality and some micronutrients (potassium, magnesium, vitamin A-D-K-C-81-86, Folate) but no significant correlation was found between anxiety, depression, and stress scores
Re-Functioning of Pembe Yalı: Evaluation Within the Scope of Turkey Architectural Heritage Conservation Charter and Principles for the Conservation of Wooden Built Heritage
(Abidin Temizer, 2025) Ural, A.G.
It is known that Pembe Yalı, located in Beykoz District of Istanbul Province, was built in the 19th century. The building has the importance of being one of the 366 mansions in the Bosphorus, which are historical monuments. The aim of the study was to evaluate the project in the context of Icomos Turkey Architectural Heritage Conservation Charter. While preparing the study, the general scanning model and the documentary scanning model from qualitative research methods were used. By using the documentary scanning method, the old and new projects and photographs of the Pembe Yalı, which is the subject of the research, were accessed. The restoration process of the building, whose projects were prepared by the author and her team, was compiled from project and application experiences. Using the documentary scanning model, the Turkey Architectural Heritage Conservation Charter was examined and the Principles for the Conservation of Wooden Built Heritage were also taken into consideration. The findings were evaluated using the content analysis method. In the research, it is aimed to evaluate the structural problems, the methods used and the analysis and the refunctioning process of the Pink Mansion in the design phase. © 2025 Elsevier B.V., All rights reserved.
Child And Adolescent Mindfulness Measure Turkish Validity And Reliability Study;
(Galenos Publishing House, 2024) Bilaç, Ö.; Dikeç, G.; Akyol, C.K.; Kale, M.K.; Sapmaz, Ş.Y.; Kandemir, H.; Aydemir, Ö.
Objectives: The number of studies on mindfulness in children and adolescents has rised in recent years, and it is crucial to evaluate the mindfulness-based interventions applied with standardized measurement tools. This aim of this study was to make the Turkish language validity and reliability of the Child and Adolescent Mindfulness Measure (CAMM), which can be used in children and adolescents about mindfulness, which has been very well-liked in recent years, and which has validity and reliability in many languages, and to bring it into our language for the ages of 9-18. Materials and Methods: The total sample of the current study consisted of 156 children and adolescents, 48 of whom were children and adolescents with any mental disorderdiagnosis according to Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5). One hundred eight of them did not have any mental disorders diagnosis according to DSM-5, who had only periodic problems or were brought for counseling. Results: In the reliability analysis of the scale, the Cronbach’s alpha coefficient was found to be 0.76 for the whole scale. In test-retest reliability two weeks apart, the two measurements have a strong correlation between the measurements (r=0.634 p<0.0001). Conclusion: In conclusion, our findings show that the Turkish version of the CAMM is a valid and reliable measurement tool for the 9-18 age group. © 2024, Galenos Publishing House. All rights reserved.
In Vitro Efficacy of Sumac (Rhus coriaria) Extracts Against Leishmania Tropicana and Leishmania Mexicana: A Preliminary Study from Turkiye
(Istanbul Univ, 2025) Mete, Ergun; Ozel, Yener; Bardakci, Hilal; Durmuskahya, Cenk; Koseler, Aylin; Kurt, Ozgur
Objective: Cutaneous leishmaniasis (CL) is a common clinical manifestation of leishmaniasis. Here, the in vitro anti-leishmanial efficacy of sumac extracts was tested for the first time on both Leishmania (L.) tropica and L. mexicana isolates using Rhus (R.) coriaria plant, which was collected in western Anatolia. Materials and Methods: The dried and powdered fruits of R. coriaria were macerated in acetone, ethyl alcohol, and ethyl alcohol-water mixture at room temperature for two days. The pooled extracts were evaporated under reduced pressure and lyophilized form for the study. Isolates of L. tropica and L. mexicana in Acibadem University R&D Laboratory were initially thawed and cultivated in NNN medium. Assessments were made using the haemocytometer and MTT methods at 24 and 48 h, compared with meglumine antimoniate as the control group. Results: For L. tropica, the effective concentration ranges of the extracts and the infusion were found to be 578.13-289.06 pg/mL and 289.06-144.53 pg/mL, respectively. For L. mexicana, the ranges were found to be 289.06-144.53 pg/mL and 144.53-72.27 pg/mL, respectively. It was shown that all extracts of R. coriaria were effective against both L. tropica and L. mexicana in higher doses, compared to meglumine antimoniate. Conclusion: An interesting finding was that higher sumac doses were required to eliminate L. tropica of the Old World, compared to L. mexicana of the New World. In addition, the aqueous alcohol extract showed efficacy that lasted for 48 h in half doses compared to others in L. tropica. Further assessments for both the identification of the active compounds within R. coriaria and their efficacy in vivo are planned.
Determination of Age- and Gender-Specific Reference Values for Different Functional Tests with or without Cognitive Dual-Task in Young Adults: An Observational Study
(Turkey Assoc Physiotherapists, 2025) Analay Akbaba, Yildiz; Emirza Cilbir, Cigdem; Poyraz Isleyen, Tugce; Evrendilek, Halenur; Gungor Eroglu, Nazli; Asena Yekdaneh, Aye; Gungor, Feray
Purpose: To determine the age-and gender-specific reference values for the five functional tests performed with or without cognitive dual-task in young adults. Methods: In this cross-sectional observational study, a total of 107 participants were divided into four subgroups based on gender and age: females 18-25 years (G1), and 26-35 years (G2), and males 18-25 years (G3), and 26-35 years (G4). Participants completed the timed up and go test (TUG), 4 meter gait speed test, 10 meter walk test (10MWT), timed 25-foot walk test, and 1 minute sit-to-stand test (1MSTS) with and without dual-tasks. The mean value of each test was recorded. Results: Significant differences were observed in some functional tests. TUG was longer in G1 compared to G2 (p=0.019), 10MWT dual-task performance differed between G1 and G3 (p=0.041), and 1MSTS and 1MSTSdual scores were higher in G3 compared to G4 (p=0.044 and p=0.035, respectively). All dual-task conditions led to decreased performance compared to single-task conditions (p<0.001) Conclusion: The dual-task added to the performance tests changes the time, speed, and number of repetitions in healthy individuals, and these effects may vary according to age and gender. These reference values can guide clinical assessments of dual-task performance in this population.
Citation - WoS: 3
Citation - Scopus: 4
Oral Pharmabiotic Tablet Formulations
(Marmara Univ, 2024) Kandur, Buse; Ugurlu, Timucin; Rayaman, Erkan; Ahbaz, Sevinc S.
Pharmabiotic is a unique and recent term used to describe formulations containing probiotics. Pharmabiotics are probiotics prepared in a pharmaceutical form used to treat diseases and disorders by making physicochemical changes in human health. Probiotics, prebiotics, and synbiotics are included in this scope, and enzobiotics, which are a rising class of supplements, should be evaluated in this context, as they are a subspecies of synbiotics. Pharmabiotics, unlike nutribiotics, do not necessarily contain live microorganisms. The best examples of these are paraprobiotics and postbiotics. Tablet formulations are suitable dosage forms for pharmabiotics due to their redundant superiority over other solid dosage forms. Tablets are frequently preferred because they can be produced at low cost, are easily transported, and modified, are suitable for large-scale production, and are more stable than other dosage forms. Considering the examples in the literature and the definition of pharmabiotic, several tablet formulations can be mentioned as pharmabiotics. They can be divided into conventional uncoated tablets, chewable tablets, and effervescent tablets. With recent studies, this classification has expanded, and buccal mucoadhesive tablets, ODTs (orally disintegrating tablets) and FDTs (fast disintegrating tablets), layered/multi-layered tablets, and tablets within tablets have also taken their place in the classification. This article focuses on oral tablet formulations that can be classified as pharmabiotics.
Determination of Post-Earthquake Trauma Level and Investigation of the Relationship with Physical Activity Status
(Turkish Physiotherapy Association, 2025) Tosun, Anil; Yılmaz, Nergis; Luque, Demet Tekın De Las Penas
Amaç: Çalışmanın amacı; 06 Şubat 2023’te meydana gelen Pazarcık-Elbistan merkezli depremler sebebiyle kişilerde oluşan travma düzeyinin, kişinin fiziksel aktivite durumu ile ilişkisini incelemektir. Aynı zamanda, kişilerde deprem sonrası ağrı varlığının sorgulanması ve bu durumun travma düzeyi ile ilişkisini ortaya koymaktır. Yöntem: Veriler çevrimiçi olarak Google formları aracılığıyla toplandı, 18-65 yaş arası 388 gönüllü katılımcı (299 kadın, 89 erkek) çalışmaya dahil edildi. Katılımcıların genel özelliklerini belirlemek için “Sosyodemografik Bilgi Formu”, travma düzeyini değerlendirmek için “Deprem Sonrası Travma Düzeyini Belirleme Ölçeği” (DSTDBÖ) ve fiziksel aktivite durumlarını belirlemek için “Uluslararası Fiziksel Aktivite Anketi Kısa Formu” (IPAQ-KF) kullanıldı. Bulgular: Deprem bölgesinde bulunma durumuna göre DSTDBÖ genel puan ortalamaları arasında anlamlı fark saptandı (p<0,001). Deprem bölgesinde bulunan 126 kişinin DSTDBÖ genel puan ortalaması 57,66±19,87 iken, bölgede bulunmayan 262 kişinin ortalaması 49,00±18,49 olarak bulundu. Spearman korelasyon analiziyle deprem bölgesinde olan ve olmayan bireylerin IPAQ-KF toplam puanları, DSTDBÖ alt faktör ve toplam puanları arasındaki ilişki incelenmiş olup sadece “Bilişsel Yapılandırma” alt faktörü ile IPAQ-KF toplam puanları arasında anlamlı bir ilişkiyi yansıtmayan negatif zayıf ilişki bulundu (deprem bölgesinde olanlar için Spearman korelasyon katsayı değeri =-0,18, p=0,042). Ve deprem sonrası ağrı yaşayan bireylerin DSTDBÖ puanları, ağrı yaşamayanlardan daha yüksek olarak saptandı (p=0,000). Sonuç: Bu çalışma ile deprem sonrası travma düzeyinin, fiziksel aktivite ile negatif ilişki gösterdiği belirlendi. İnaktif bireyler daha yüksek travma düzeylerine sahipken, minimal aktif bireylerde travma düzeyleri daha düşük bulundu. Bu bulgular, deprem sonrası fiziksel aktivitenin artırılmasının travma düzeylerini azaltmada etkili bir strateji olabileceğini göstermektedir. Bu alanda daha fazla araştırma, eğitim ve proje çalışmalarının yapılması gerekmektedir.
The Correlation Between Vitamin D Levels and Thyroid Functions in Early Pregnancy
(Yuzuncu Yil Universitesi Tip Fakultesi, 2025) Dinmez, Sinem; Özlem, Dülger; Oğul, Zeynep
Vitamin D deficiency (serum vitamin D <10 ng/ml) and thyroid dysfunctions are prevalent issues globally, particularly during pregnancy. Evidence suggests a potential link between thyroid function and vitamin D levels. This study aims to investigate the correlation between serum vitamin D levels and thyroid functions in wome n during the first trimester of pregnancy. The study was conducted retrospectively at a University Education and Research Hospital’s pregnancy clinic, covering data from August 2023 to March 2024. The sample group consisted of first -trimester pregnant women who attended routine pregnancy check-ups and had complete vitamin D levels and thyroid function tests (n=185). The sociodemographic data form and blood serum level assessment forms were used as data collection tools. The data were analyzed using descriptive statistics and correlation analysis. The average age of the pregnant women participating in our study was 27.6±4.9 years, and the Body Mass Index (BMI) was 25.4±4.8 (overweight). The mean number of pregnancies was 1.13±0.3, and the gestational week was 8.19±1.8. Of the participants, 35 had subclinical hypothyroidism, 37 had thyroiditis, and 113 had normal thyroid functions. The study identified 36 women with normal/adequate vitamin D levels (≥20 ng/ml), 113 with vitamin D insufficiency (10–20 ng/ml), and 36 with vitamin D deficiency (<10 ng/ml). The correlation analysis revealed no significant relationship between the thyroid function tests and vitamin D levels of the pregnant women. It was determined that vitamin D levels do not affect thyroid gland function in the first trimester.
Citation - Scopus: 3
Comparison of the Hidden Curriculum for Nursing Education of Two Different Universities in the East and West of Turkiye
(Inonu University, 2024) Elmali Şimşek, H.; Aksoy, M.
The present study aimed to determine and compare the hidden curriculum of two institutions that provide undergraduate nursing education in two different regions of Türkiye. The descriptive and cross-sectional research was conducted with 319 nursing students. Data were collected with the Introductory Information Form and Hidden Curriculum Evaluation Scale in Nursing Education (HCES-N). While the mean score of the HCES-N total score of the nursing students attending the university in the West of Türkiye was 163.31 ± 21.69. The HCES-N total mean score of the nursing students attending in the East of Türkiye was calculated as 145.50 ± 25.81. While the HCES-N total score, school atmosphere, and professional achievement scores of the nursing students attending the university in the West of Türkiye were statistically higher than the nursing students attending the university in the east, the student-teacher-school interaction score was statistically lower. It was determined that the perceptions of the students participating in the study towards the hidden curriculum were moderate, while the perceptions of the students studying in the West of Türkiye were better. In line with these results, it is important to improve the physical conditions of schools in improving the hidden curriculum. © 2024, Inonu University. All rights reserved.
Citation - Scopus: 1
The Relationship Between Turnover Intention And Compulsory Citizenship Behaviour Of Nurses
(Association of Executive Nurses, 2024) Selçuk, D.; Harmancı Seren, A.K.
Aim: This study aimed to examine whether there is a relationship between turnover intention and compulsory citizenship behavior among nurses working in a training and research hospital in Istanbul. Method: The data of this descriptive and relationship-seeking study were collected with the participation of 191 nurses working in a training and research hospital in İstanbul between December 2016 and February 2017. Research data was collected through a questionnaire aimed at learning participants' personal information, Turnover Intention Scale and Compulsory Citizenship Behavior Scale. Data was analyzed on a computer. Descriptive statistics, parametric and non-parametric comparison analyze and Pearson correlation analyzes were performed. Results: Point averages of the nurses between “Turnover Intention Scale” and “Compulsory Citizenship Behavior Scale” were 2.90 (SD=1.11) and 3.42 (SD=0.90) respectively. The correlation coefficient for the relationship between the intention to quit the job and compulsory citizenship behavior was found to be r=0.315 (p<0.001). Conclusion: It has been determined that nurses have the intention to leave the job below the medium level, they exhibit compulsory citizenship behavior at the above medium level, and there is a positive, medium strength and very significant linear relationship between the intention to leave the job and the compulsory citizenship behaviour. © 2024 The Authors.
The Challenges Experienced by International Nursing Students in Nursing Education: a Qualitative Study
(Ataturk Univ, 2024) Elmali Simsek, Hulya; Karali, Ece; Arslan, Gunay
Objective: The study aimed to determine the challenges experienced by international nursing undergraduate students during their education period. Methods: A phenomenological research design was used. The study was conducted with 20 international nursing students enrolled in a foundation university in T & uuml;rkiye. Colaizzi's phenomenological data analysis method was employed in the study. Results: Based on the study's results, three main themes, 'Learning in a different environment', 'Challenges', 'Solution-Non Solution' and 'System difference, Language problems in clinical practice, Broad nursing curriculum, Facilitators, Language barrier, Feeling homesick, Racism and discrimination, Housing difficulties, Lack of funding, Instant solution, Failing to find a solution sub-themes themes were created. Conclusion: It has been observed that students experience different environments, uncertainties, and various challenges, and that these situations directly affect their education and success. To that end, both the institutions they receive education and the academicians must support the students in various ways.

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