Molecular Characterization of Resistance and Virulence Genes in Enterococcus Faecium Strains Isolated Between 2000-2021; Systematic Review

dc.authorwosid Kılbaş, Elmas/HRC-3339-2023
dc.authorwosid Ciftci, Ihsan Hakki/ADQ-5984-2022
dc.contributor.author Kahraman Kılbaş, Elmas Pınar
dc.contributor.author Kilbas, Imdat
dc.contributor.author Ciftci, Ihsan Hakki
dc.contributor.other Tıbbi Hizmetler ve Teknikler Bölümü
dc.date.accessioned 2025-01-11T13:00:43Z
dc.date.available 2025-01-11T13:00:43Z
dc.date.issued 2022
dc.department Fenerbahçe University en_US
dc.department-temp [Kahraman Kilbas, Elmas Pinar] Fenerbahce Univ, Med Lab Tech Program, Vocat Sch Hlth Serv, Istanbul, Turkey; [Kilbas, Imdat] Istanbul Univ, Inst Hlth Sci, PhD Med Microbiol, Istanbul, Turkey; [Ciftci, Ihsan Hakki] Sakarya Univ, Dept Med Microbiol, Fac Med, Sakarya, Turkey en_US
dc.description.abstract Introduction: The spread of Vancomycin-Resistant Enterococci (VRE) is a major threat in healthcare institutions, especially for patients in the risk group. The aim of this study is to reveal the antibiotic resistance genes, virulence genes and other accompanying factors detected in vancomycin resistant Enterococcus faecium strains isolated from various clinical specimens in different parts of Turkiye. Material and Methods: For this purpose, a systematic search was carried out using different electronic databases between January 2000 and September 2021. A total of 17 studies were evaluated within the scope of systematic review. Results: The vanA gene was detected the most between the years 2000-2007, and no statistically significant difference was found according to the years. The prevalence of the vanB gene was highest between 2008 and 2013, and no statistical difference was found according to the years (p> 0.05). The vanA gene was mostly detected in Eastern Anatolia, Black Sea, Mediterranean and Aegean, vanB Central Anatolia and Southeastern Anatolia regions. No reports related to the vanC gene were found. Since all strains were E. faecium in our study, it is an expected finding that the vanC gene region was never reported. The esp and hyl gene between 2014-2021. Conclusion: The prevalence of resistance and virulence genes among bacteria is a matter of great concern, limiting treatment options. In particular, effective measures should be taken to prevent healthcare-associated VRE infections, and each institution should report its own resistance data. en_US
dc.description.woscitationindex Emerging Sources Citation Index
dc.identifier.citation 0
dc.identifier.doi 10.5578/flora.20229613
dc.identifier.endpage 647 en_US
dc.identifier.issn 1300-932X
dc.identifier.issn 2602-2842
dc.identifier.issue 4 en_US
dc.identifier.scopusquality N/A
dc.identifier.startpage 637 en_US
dc.identifier.trdizinid 1168564
dc.identifier.uri https://doi.org/10.5578/flora.20229613
dc.identifier.uri https://hdl.handle.net/20.500.14627/62
dc.identifier.volume 27 en_US
dc.identifier.wos WOS:000926400900015
dc.language.iso tr en_US
dc.publisher Bilimsel Tip Yayinevi en_US
dc.relation.publicationcategory Diğer en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Enterococcus Spp. en_US
dc.subject Antibiotic Resistance en_US
dc.subject Vana en_US
dc.subject Vanb en_US
dc.subject Virulence Genes en_US
dc.title Molecular Characterization of Resistance and Virulence Genes in Enterococcus Faecium Strains Isolated Between 2000-2021; Systematic Review en_US
dc.type Review en_US
dc.wos.citedbyCount 0
dspace.entity.type Publication
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relation.isAuthorOfPublication.latestForDiscovery cc28c727-07ae-40d8-9418-75b409b22d85
relation.isOrgUnitOfPublication 71e25e1a-470b-4aba-b574-5311c2551e2d
relation.isOrgUnitOfPublication.latestForDiscovery 71e25e1a-470b-4aba-b574-5311c2551e2d

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