Synergistic Anticancer Effects of the PLK1 Inhibitor BI-2536 and β-Glucan in Colon and Gastric Cancer Cells
| dc.contributor.author | Saraç, Bülent | |
| dc.contributor.author | Joha, Ziad | |
| dc.contributor.author | Takci, Rabia Gökçe | |
| dc.contributor.author | Hacisüleyman, Levent | |
| dc.contributor.author | Şahİnbaş, Burcu | |
| dc.date.accessioned | 2026-05-12T15:04:04Z | |
| dc.date.available | 2026-05-12T15:04:04Z | |
| dc.date.issued | 2026 | |
| dc.description.sponsorship | Research Projects Commission; Sivas Cumhuriyet Üniversitesi, (T-2022-987); Sivas Cumhuriyet Üniversitesi | |
| dc.description.sponsorship | pro-apoptotic effects in HT-? 笀 colon and AGS gastricFunding? cancer cell lines, primarily through G2/M cell cycle arrest. Importantly, the combination of BI-2536 with This study was funded by Sivas Cumhuriyet University the immunomodulator β-glucan enhanced these effects, Scienti ?ic Research Projects Commission (Project No: showing synergistic interactions and allowing for ef 퀀icacy T-球爃球琁笃稃礁 Doctoral Thesis Project, CUBAP, Türkiye). at lower drug concentrations. | |
| dc.description.sponsorship | This study was funded by Sivas Cumhuriyet University Scientific Research Projects Commission (Project No: T-2022-987, Doctoral Thesis Project, CUBAP, Türkiye). | |
| dc.identifier.doi | 10.21873/anticanres.18041 | |
| dc.identifier.issn | 0250-7005 | |
| dc.identifier.scopus | 2-s2.0-105031753611 | |
| dc.identifier.uri | https://hdl.handle.net/123456789/1544 | |
| dc.identifier.uri | https://doi.org/10.21873/anticanres.18041 | |
| dc.language.iso | en | |
| dc.publisher | International Institute of Anticancer Research | |
| dc.relation.ispartof | Anticancer Research | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | Β-glucan | |
| dc.subject | Gastric Cancer | |
| dc.subject | Cell Cycle | |
| dc.subject | Colon Cancer | |
| dc.subject | PLK1 | |
| dc.subject | Apoptosis | |
| dc.subject | BI-2536 | |
| dc.title | Synergistic Anticancer Effects of the PLK1 Inhibitor BI-2536 and β-Glucan in Colon and Gastric Cancer Cells | en_US |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| gdc.author.scopusid | 57781078400 | |
| gdc.author.scopusid | 60046510300 | |
| gdc.author.scopusid | 57302291600 | |
| gdc.author.scopusid | 60046601400 | |
| gdc.author.scopusid | 6508124395 | |
| gdc.description.department | ||
| gdc.description.departmenttemp | [Takci R.G.] Faculty of Medicine, Pharmacy, Sivas Cumhuriyet University, Sivas, Turkey; [Saraç B.] Faculty of Medicine, Pharmacy, Sivas Cumhuriyet University, Sivas, Turkey; [Hacisüleyman L.] Faculty of Pharmacy, Fenerbahçe University, Istanbul, Turkey; [Şahİnbaş B.] Faculty of Medicine, Pharmacy, Sivas Cumhuriyet University, Sivas, Turkey; [Joha Z.] Ziad Joha, Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas, 58140, Turkey | |
| gdc.description.endpage | 1474 | |
| gdc.description.issue | 3 | |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| gdc.description.startpage | 1461 | |
| gdc.description.volume | 46 | |
| gdc.identifier.pmid | 41760244 | |
| gdc.index.type | PubMed | |
| gdc.index.type | Scopus |