The Protective Effects of Myrtus Communis Subsp. on Ovariectomized Diabetic Rats’ Renal and Intestinal Tissues: in Vivo and in Silico Approaches
| dc.contributor.author | Ertik, O. | |
| dc.contributor.author | Kadıoğlu-Yaman, Beril | |
| dc.contributor.author | Şen, Ali | |
| dc.contributor.author | Şener, Göksel | |
| dc.contributor.author | Yanardag, Refiye | |
| dc.contributor.other | Eczacılık Meslek Bilimleri Bölümü | |
| dc.date.accessioned | 2025-01-11T13:03:20Z | |
| dc.date.available | 2025-01-11T13:03:20Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Introduction: Postmenopausal diabetes is a condition that affects millions of women and their quality of life. Also, kidney and small intestine tissues are damaged due to diabetes. The present study aimed to examine the protective effects of an extract prepared from Myrtus communis leaves on kidney and small intestine tissues against experimentally created postmenopausal diabetes. Methods: For this purpose, experimental rats were randomly divided into six groups (Control; ovariectomy:OVX, diabetic:D, ovariectomy + diabetic:OVX + D, ovariectomy + diabetic + oestrogen:OVX + D+E2, ovariectomy + diabetic + MC: OVX + D+MC) and kidney and small intestine tissues were taken after the experimental procedure. Results: Evaluations of biochemical parameters (glutathione and glutathione-related enzymes, antioxidant enzymes, etc.) showed that MC had a protective effect on kidney and small intestine tissues in diabetes and ovariectomy groups. Conclusion: It can be suggested that MC extract has a protective effect on small intestine and kidney tissues in postmenopausal diabetes and may be a good herbal source for this purpose. © 2024 Informa UK Limited, trading as Taylor & Francis Group. | en_US |
| dc.identifier.citation | 0 | |
| dc.identifier.doi | 10.1080/13813455.2024.2406895 | |
| dc.identifier.issn | 1381-3455 | |
| dc.identifier.scopus | 2-s2.0-105002050453 | |
| dc.identifier.uri | https://doi.org/10.1080/13813455.2024.2406895 | |
| dc.language.iso | en | en_US |
| dc.publisher | Taylor and Francis Ltd. | en_US |
| dc.relation.ispartof | Archives of Physiology and Biochemistry | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Diabetes | en_US |
| dc.subject | In Silico | en_US |
| dc.subject | Myrtus Communis | en_US |
| dc.subject | Ovariectomize | en_US |
| dc.subject | Oxidative Stress | en_US |
| dc.title | The Protective Effects of Myrtus Communis Subsp. on Ovariectomized Diabetic Rats’ Renal and Intestinal Tissues: in Vivo and in Silico Approaches | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | Sener, Goksel/0000-0001-7444-6193 | |
| gdc.author.id | ERTIK, Onur/0000-0001-5437-3513 | |
| gdc.author.id | Kadioglu Yaman, Suha Beril/0000-0001-8887-4826 | |
| gdc.author.institutional | Şener, Göksel | |
| gdc.author.scopusid | 57199398578 | |
| gdc.author.scopusid | 59345191900 | |
| gdc.author.scopusid | 55250649800 | |
| gdc.author.scopusid | 55662834600 | |
| gdc.author.scopusid | 6701546641 | |
| gdc.description.department | Fenerbahçe University | en_US |
| gdc.description.departmenttemp | [Ertik O.] Faculty of Engineering, Department of Chemistry, Istanbul University-Cerrahpaşa, Avcilar, Istanbul, Turkey, Faculty of Engineering and Science, Department of Chemistry, Bursa Technical University, Bursa, Yildirim, Turkey; [Kadıoğlu-Yaman B.] Faculty of Pharmacy, Department of Pharmacology, Başkent University, Etimesgut, Ankara, Turkey; [Şen A.] Faculty of Pharmacy, Department of Pharmacognosy, Marmara University, Maltepe, Istanbul, Turkey; [Şener G.] Faculty of Pharmacy, Department of Pharmacology, Fenerbahçe University, Atasehir, Istanbul, Turkey; [Yanardag R.] Faculty of Engineering, Department of Chemistry, Istanbul University-Cerrahpaşa, Avcilar, Istanbul, Turkey | en_US |
| gdc.description.endpage | 226 | en_US |
| gdc.description.issue | 2 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q2 | |
| gdc.description.startpage | 210 | en_US |
| gdc.description.volume | 131 | en_US |
| gdc.description.woscitationindex | Science Citation Index Expanded | |
| gdc.description.wosquality | Q2 | |
| gdc.identifier.pmid | 39324246 | |
| gdc.identifier.wos | WOS:001320739100001 | |
| gdc.scopus.citedcount | 0 | |
| gdc.wos.citedcount | 0 | |
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