The Protective Effects of <i>myrtus Communis</I> Subsp. on Ovariectomized Diabetic Rats' Renal and Intestinal Tissues: <i>in Vivo</I> and <i>in Silico</I> Approaches

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dc.authoridSener, Goksel/0000-0001-7444-6193
dc.authoridERTIK, Onur/0000-0001-5437-3513
dc.authoridKadioglu Yaman, Suha Beril/0000-0001-8887-4826
dc.authorscopusid57199398578
dc.authorscopusid59345191900
dc.authorscopusid55250649800
dc.authorscopusid55662834600
dc.authorscopusid6701546641
dc.authorwosidKadıoğlu Yaman, Beril/IXD-6478-2023
dc.authorwosidErtik, Onur/GWC-1868-2022
dc.contributor.authorŞener, Göksel
dc.contributor.authorKadioglu-Yaman, Beril
dc.contributor.authorSen, Ali
dc.contributor.authorSener, Goksel
dc.contributor.authorYanardag, Refiye
dc.contributor.otherEczacılık Meslek Bilimleri Bölümü
dc.date.accessioned2025-01-11T13:03:20Z
dc.date.available2025-01-11T13:03:20Z
dc.date.issued2024
dc.departmentFenerbahçe Universityen_US
dc.department-temp[Ertik, Onur; Yanardag, Refiye] Istanbul Univ Cerrahpasa, Fac Engn, Dept Chem, Istanbul, Turkiye; [Ertik, Onur] Bursa Tech Univ, Fac Engn & Sci, Dept Chem, Bursa, Turkiye; [Kadioglu-Yaman, Beril] Baskent Univ, Fac Pharm, Dept Pharmacol, Ankara, Turkiye; [Sen, Ali] Marmara Univ, Fac Pharm, Dept Pharmacognosy, Istanbul, Turkiye; [Sener, Goksel] Fenerbahce Univ, Fac Pharm, Dept Pharmacol, Istanbul, Turkiyeen_US
dc.descriptionSener, Goksel/0000-0001-7444-6193; ERTIK, Onur/0000-0001-5437-3513; Kadioglu Yaman, Suha Beril/0000-0001-8887-4826en_US
dc.description.abstractIntroductionPostmenopausal diabetes is a condition that affects millions of women and their quality of life. Also, kidney and small intestine tissues are damaged due to diabetes. The present study aimed to examine the protective effects of an extract prepared from Myrtus communis leaves on kidney and small intestine tissues against experimentally created postmenopausal diabetes. MethodsFor this purpose, experimental rats were randomly divided into six groups (Control; ovariectomy:OVX, diabetic:D, ovariectomy + diabetic:OVX + D, ovariectomy + diabetic + oestrogen:OVX + D+E2, ovariectomy + diabetic + MC: OVX + D+MC) and kidney and small intestine tissues were taken after the experimental procedure. ResultsEvaluations of biochemical parameters (glutathione and glutathione-related enzymes, antioxidant enzymes, etc.) showed that MC had a protective effect on kidney and small intestine tissues in diabetes and ovariectomy groups. ConclusionIt can be suggested that MC extract has a protective effect on small intestine and kidney tissues in postmenopausal diabetes and may be a good herbal source for this purpose.en_US
dc.description.woscitationindexScience Citation Index Expanded
dc.identifier.citation0
dc.identifier.doi10.1080/13813455.2024.2406895
dc.identifier.issn1381-3455
dc.identifier.issn1744-4160
dc.identifier.pmid39324246
dc.identifier.scopus2-s2.0-85205073336
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1080/13813455.2024.2406895
dc.identifier.urihttps://hdl.handle.net/20.500.14627/259
dc.identifier.wosWOS:001320739100001
dc.identifier.wosqualityQ2
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMyrtus Communisen_US
dc.subjectDiabetesen_US
dc.subjectOxidative Stressen_US
dc.subjectOvariectomizeen_US
dc.subjectIn Silicoen_US
dc.titleThe Protective Effects of <i>myrtus Communis</I> Subsp. on Ovariectomized Diabetic Rats' Renal and Intestinal Tissues: <i>in Vivo</I> and <i>in Silico</I> Approachesen_US
dc.typeArticleen_US
dspace.entity.typePublication
relation.isAuthorOfPublication68ac39be-51c5-4820-a6c9-0bef06348d93
relation.isAuthorOfPublication.latestForDiscovery68ac39be-51c5-4820-a6c9-0bef06348d93
relation.isOrgUnitOfPublication5052e089-e75d-4aec-a280-6353973e4819
relation.isOrgUnitOfPublication.latestForDiscovery5052e089-e75d-4aec-a280-6353973e4819

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