Karagöz, Atakan

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Profile URL
https://hdl.handle.net/20.500.14627/636
Name Variants
Karagoz, A.
Karagoz, A.
Job Title
Öğretim Görevlisi
Email Address
atakan.karagoz@fbu.edu.tr
Main Affiliation
Dişçilik Hizmetleri Bölümü
Status
Website
ORCID ID
0000-0002-6310-1752
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
JJR-1963-2023
Files
photo_384185.jpg.JPG (2.03 MB)

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4

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1

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0

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2024 - 20253
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Now showing 1 - 3 of 3
  • Thumbnail Image
    Conference Object
    Toothpastes with Different Detergent Contents Affect Morphogenesis and Redox System Parameters in Zebrafish Embryos
    (Wiley, 2025) Karagoz, Atakan; Beler, Merih; Egilmezer, Gizem; Unal, Ismail; Cansiz, Derya; Emekli-Alturfan, Ebru
  • Thumbnail Image
    Conference Object
    Toothpastes with Different Detergent Contents Affect Morphogenesis and Redox System Parameters in Zebrafish Embryos
    (Wiley, 2024) Karagoz, A.; Beler, M.; Unal, I.; Cansiz, D.; Emekli-Alturfan, E.
  • Thumbnail Image
    Article
    Biocompatibility Assessment of Chlorhexidine Gluconate Versus a Natural Mouthwash Containing Olea Europaea and Opuntia Ficus-Indica in Zebrafish Embryos
    (2025) Ünal, İsmail; Emekli-Alturfan, Ebru; Cansız, Derya; Yalcinkaya, Sebnem Ercalik; Beler, Merih; Eğilmezer, Gizem; Karagöz, Atakan
    Various chemical solutions are available for oral hygiene and care, but these chemical solutions also cause various side effects in living systems. Therefore, the trend towards the production of highly biocompatible, natural-based oral care products has increased. This study aimed to compare the biocompatibility profiles of a conventional chlorhexidine gluconate-based mouthwash and a natural formulation containing Olea europaea leaf and Opuntia ficus-indica extracts using the zebrafish embryo model. Zebrafish embryos were exposed to two concentrations (100 ppm and 1000 ppm) of each mouthwash for 72 hours post-fertilization. Developmental properties such as mortality, hatching rate, pericardial edema, and body length were evaluated. Biochemical analyses included oxidative stress parameters and acetylcholinesterase (AChE) activity. Chlorhexidine exposure resulted in increased embryonic mortality, pericardial edema, and reduced body length. Biochemically, chlorhexidine increased lipid peroxidation and glutathione S-transferase (GST) activity while decreasing superoxide dismutase (SOD) and AChE activities. In contrast, embryos exposed to the natural formulation showed no significant developmental abnormalities and exhibited increased SOD and AChE activities without changes in lipid peroxidation. These findings provide evidence regarding the differential biocompatibility of synthetic and plant-based mouthwashes in early developmental models.