Karagöz, Atakan

Profile URL
https://hdl.handle.net/20.500.14627/636
Name Variants
Karagoz, A. Karagoz, A.
Job Title
Öğretim Görevlisi
Email Address
atakan.karagoz@fbu.edu.tr
Main Affiliation
Dişçilik Hizmetleri Bölümü
Status
Website
ORCID ID
0000-0002-6310-1752
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
JJR-1963-2023
Files
photo_384185.jpg.JPG (2.03 MB)

Research Topics

Domains
Health SciencesLife Sciences
Fields
MedicineAgricultural and Biological Sciences
Subfields
Radiology, Nuclear Medicine and ImagingPulmonary and Respiratory MedicineFood SciencePlant Science
Specific Research Areas
Effects of Radiation Exposure
Radiation Dose and Imaging
Radiation Therapy and Dosimetry
Botanical Research and Applications
Plant Stress Responses and Tolerance

Sustainable Development Goals

SDG data is not available

Publication Collaboration

Affiliation Name Count
Istanbul Medipol University 6
Marmara University 6
Istanbul University-Cerrahpaşa 4
Fenerbahçe University 3
Istanbul University 1
1 / 2
Data obtained from OpenAlex
Scholarly Output

7

Articles

2

WoS Citation Count

0

Scopus Citation Count

0

Filters

2024 - 20267

Settings

Author of Publication: search.filters.isAuthorOfPublication.5bc48b7d-2b15-48b5-b944-8fd170a44c33

Scholarly Output Search Results

Now showing 1 - 7 of 7
  • Conference Object
    Toothpastes with Different Detergent Contents Affect Morphogenesis and Redox System Parameters in Zebrafish Embryos
    (Wiley, 2024) Karagoz, Atakan; Beler, Merih; Egilmezer, Gizem; Unal, Ismail; Cansiz, Derya; Emekli-Alturfan, Ebru
  • Conference Object
    Effects of Blue Led Light Exposure on Early Development and Craniofacial Morphology in Zebrafish Embryos
    (Wiley, 2026) Unal, I; Karagoz, A.; Emekli-Alturfan, E.; Mizrak, Z.; Beler, M.; Egilmezer, G.; Akkus-Yaylamis, E., I
  • Conference Object
    Toothpastes with Different Detergent Contents Affect Morphogenesis and Redox System Parameters in Zebrafish Embryos
    (Wiley, 2024) Karagoz, A.; Beler, M.; Unal, I.; Cansiz, D.; Emekli-Alturfan, E.
  • Other
    Low-Dose Ionising Radiation Exerts Effects Comparable to MPTP through Alterations in Locomotor Activity, Oxidant/Antioxidant Status and Mitochondrial Homeostasis in Zebrafish Embryos
    (2025) Ünal, İsmail; Bayramov, Ezgi Cahide Aydaş; Yaltkaya, Selma; Beler, Merih; Yalçınkaya, ̧şebnem Erçalık; Eğilmezer, Gizem; Cansız, Derya
  • Article
    Biocompatibility Assessment of Chlorhexidine Gluconate Versus a Natural Mouthwash Containing Olea Europaea and Opuntia Ficus-Indica in Zebrafish Embryos
    (2025) Ünal, İsmail; Emekli-Alturfan, Ebru; Cansız, Derya; Yalcinkaya, Sebnem Ercalik; Beler, Merih; Eğilmezer, Gizem; Karagöz, Atakan; Bayramov, Ezgi Cahide Aydaş; Emekli‐alturfan, Ebru; Akkuş, E.; Yaltkaya, Selma; Ozel, Armagan Begum
    Various chemical solutions are available for oral hygiene and care, but these chemical solutions also cause various side effects in living systems. Therefore, the trend towards the production of highly biocompatible, natural-based oral care products has increased. This study aimed to compare the biocompatibility profiles of a conventional chlorhexidine gluconate-based mouthwash and a natural formulation containing Olea europaea leaf and Opuntia ficus-indica extracts using the zebrafish embryo model. Zebrafish embryos were exposed to two concentrations (100 ppm and 1000 ppm) of each mouthwash for 72 hours post-fertilization. Developmental properties such as mortality, hatching rate, pericardial edema, and body length were evaluated. Biochemical analyses included oxidative stress parameters and acetylcholinesterase (AChE) activity. Chlorhexidine exposure resulted in increased embryonic mortality, pericardial edema, and reduced body length. Biochemically, chlorhexidine increased lipid peroxidation and glutathione S-transferase (GST) activity while decreasing superoxide dismutase (SOD) and AChE activities. In contrast, embryos exposed to the natural formulation showed no significant developmental abnormalities and exhibited increased SOD and AChE activities without changes in lipid peroxidation. These findings provide evidence regarding the differential biocompatibility of synthetic and plant-based mouthwashes in early developmental models.
  • Conference Object
    Structural and Biochemical Alterations in Zebrafish Embryos Exposed to Toothpastes with Different Detergent Contents
    (Wiley, 2025) Karagoz, A.; Beler, M.; Egilmezer, G.; Unal, I.; Cansiz, D.; Emekli, E.
  • Article
    Low Dose Ionising Radiation Elicits MPTP Comparable Alterations in Locomotor Function, Oxidative Balance and Mitochondrial Homeostasis in Zebrafish Embryos
    (Nature Portfolio, 2025) Cahide, Ezgi; Bayramov, Aydas; Beler, Merih; Cansiz, Derya; Unal, Ismail; Egilmezer, Gizem; Yalcinkaya, Sebnem Ercalik
    Prenatal exposure to environmental factors including low-dose ionising radiation and neurotoxins may disrupt the oxidant-antioxidant balance. Our aim was to assess the effects of exposure to low-dose ionising radiation (LDIR) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), which is a neurotoxin used to model Parkinson's disease (PD), on developing zebrafish embryos, focusing on the oxidant-antioxidant system and markers of mitochondrial damage associated with PD. Zebrafish embryos were divided into four groups: control, LDIR, MPTP, and LDIR combined with MPTP (LDIR + MPTP). A dental x-ray unit (60 kVp, 7 mA) was used for the exposures. The 0.08 s LDIR exposure was measured as 0.065 mGy using optically stimulated dosimeters. At the end of 72 h after fertilization, locomotor activities, acetylcholine esterase (AChE) activity, oxidative stress and antioxidant status were assessed. Expressions of genes associated with in PD as markers of mitochondrial damage (pink1, parkin, dj1 and lrrk2) were determined by RT-PCR. Developmental toxicity was observed in all exposure groups as evidenced by pericardial edema, yolk sac edema and spinal curvature. LDIR exposure in zebrafish embryos affected oxidative and mitochondrial stress markers, as well as locomotor activity and AChE as a marker of cognitive function at levels comparable to the MPTP exposure. Our study is the first to determine the effects of LDIR from a dental x-ray unit on the response to MPTP, and we aim to further elucidate the mechanism of these changes observed particularly in the LDIR + MPTP group.