Browsing by Author "Sel, Figen Abatay"

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    Cell-Based Therapy for Cancer in Regenerative Medicine
    (CRC Press, 2025) Sel, Figen Abatay; Oǧuz, Fatma Savran
    Regenerative medicine focuses on developing and applying new cell-based therapies to heal tissues and organs and restore function lost due to aging, disease, tissue damage, or cancer. Cancer is a complex disease. It can occur with dysfunction in multiple systems, including DNA repair and apoptotic and immune functions. One form of regenerative medicine is cancer immunotherapy. In cancer immunotherapy, the immune system is activated, replaced, engineered, or regenerated to fight cancer. Stem cells are the most widely used for cancer immunotherapy. Stem cells have a natural capacity for self-healing via asymmetric division. Mesenchymal stem cells (MSCs) are a specific group of stem cells that have the potential to be used most often in regenerative medicine. In addition to MSCs, induced pluripotent stem cells (iPSCs) and hematopoietic stem cells (HSCs) are used in regenerative medicine for cancer treatment. This chapter will discuss using different types of stem cells in other cancers and the pros and cons of using stem cell-based therapies. © 2025 Elsevier B.V., All rights reserved.