Browsing by Author "Altinok, Oyku"

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Citation - WoS: 4
Citation - Scopus: 4
Collagen Peptides and Saccharomyces Boulardii Cncm I-745 Attenuate Acetic Acid-Induced Colitis in Rats by Modulating Inflammation and Barrier Permeability
(Wiley, 2025) Altinok, Oyku; Bas, Murat; Dolanbay, Elif Gelenli; Kolgazi, Meltem; Mert, Tugay; Uslu, Unal
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by recurrent episodes of inflammation and tissue damage, with limited treatment options. This study aimed to investigate the effects of collagen peptides and Saccharomyces boulardii on acetic acid (AA)-induced colitis. Thirty-six male Sprague-Dawley rats were randomly divided into the following four groups: normal control (NC), colitis control (CC), collagen peptide (CP; 0.6 g/kg/day), and S. boulardii (SB; 250 mg/day). Colitis was induced by an intrarectal administration of AA in all groups except NC, and treatments were administered daily for 7 days. The therapeutic effects were evaluated by assessing the disease activity index (DAI), colon mass index, macroscopic and microscopic tissue damage, histopathological changes, zonula occludens (ZO)-1 protein expression, and myeloperoxidase (MPO) activity. The results showed that CP and SB treatments substantially alleviated DAI scores (p < 0.05) and reduced the colon mass index. Colon macroscopic and microscopic damages improved compared to the CC group (p < 0.01). Histologically, both treatments reduced inflammatory cell infiltration, crypt damage, and ulceration, with CP showing a slightly more pronounced effect. Immunohistochemical analysis revealed significant restoration of ZO-1 protein expression in the treated groups, indicating improvement in intestinal barrier integrity (p < 0.01). Furthermore, MPO activity was reduced in both CP and SB groups, significantly in the SB group (p < 0.01). These findings are consistent with previous studies that highlight the anti-inflammatory and barrier-enhancing effects of collagen peptides and probiotics in UC models.
Citation - WoS: 2
Citation - Scopus: 2
Coach Candidates' and Coaches' Nutrition Knowledge Affects Dietary Recommendations Indirectly: Mediator Effects of Self-Efficacy
(Mdpi, 2025) Altinok, Oyku; Bas, Murat
Background/Objectives: The nutritional knowledge and behavior of athletes are considerably influenced by the dietary recommendations of their coaches, which, in turn, affect their health and performance. In the context of social cognitive theory, this study examines the impact of general and sports nutrition knowledge (GeSNK), nutrition self-efficacy (NSE), and nutrition counseling self-efficacy (NCSE) on the dietary recommendations (DRs) provided by coach candidates and coaches (CC&Cs). Additionally, it explores variations in GeSNK, NSE, and NCSE among CC&Cs based on their sports positions, genders, and types of sports. Methods: This study included 70 coach candidates and 102 coaches, with data collected via validated scales for GeSNK, NSE, and NCSE. Using the PROCESS macro, the serial multiple mediator model was applied, and group comparisons were conducted via the Mann-Whitney U test. Results: The results revealed that 36% of participants achieved adequate GeSNK scores, but only 6.4% abstained from providing DRs. Participants engaged in individual sports exhibited higher NSE and NCSE scores than those involved in team sports. Additionally, 22.7% of CC&Cs identified their former coaches as a primary source of nutrition information. The study findings revealed that GeSNK, NSE, and NCSE significantly influenced DRs, collectively accounting for 23% of the variance in DRs. The direct effect of NCSE on DRs was statistically significant, whereas the direct effects of GeSNK and NSE were not significant. GeSNK and NSE jointly explained only 41% of the variance in NCSE, suggesting that additional factors influencing NCSE and DRs remain unexplored. Conclusions: To address the issue of inadequate dietary recommendations stemming from insufficient information, it is crucial to identify and understand these additional factors affecting NCSE and DRs. Diversifying nutrition education programs to enhance the nutrition knowledge of CC&Cs is essential. Furthermore, fostering collaboration between CC&Cs and nutritionists can ensure that athletes receive accurate and comprehensive nutritional guidance.
Beyond Age: Understanding How Mindful Eating and Food Label Reading Shape Generational Differences in Health Outcomes – A Cross-Sectional Study
(BMC, 2025) Altinok, Oyku; Yalcin, Bahar; Deniz, Melike Seyma; Celikayar, Melike Nur; Sevdin, Sezen; Bingul, Bengi Cetiner; Garipagaoglu, Muazzez
BackgroundThe increasing prevalence of obesity and diet-related chronic diseases poses a considerable threat to public health. Consequently, understanding generational differences in dietary behaviors has gained growing importance. This study aims to examine the direct and indirect effects of generational cohort on anthropometric indicators and self-rated diet quality (SRDQ), mediated through mindful eating and food label reading attitudes.MethodThis cross-sectional design study involved 2725 participants from Generations X (n = 786), Y (n = 933), and Z (n = 1006) living in Istanbul, T & uuml;rkiye. Participants' sociodemographic characteristics and anthropometric measurements, including body mass index (BMI), waist circumference (WC), and waist-hip ratio (WHR), were recorded. Data on SRDQ were collected, alongside responses to the Mindful Eating Questionnaire and the Food Label Reading Attitude Scale. Descriptive statistics, one-way analysis of variance, and chi-square tests were applied to the data. The direct and indirect effects of generation groups were analyzed using structural equation modeling.ResultsIncreasing mindful eating scores were associated with higher label reading attitude and SRDQ scores, while they were related to lower anthropometric risk indicators. Higher label reading attitudes showed an association with reduced WHR and increased SRDQ. Generation Z participants reported significantly lower scores for mindful eating, label reading attitude, anthropometric measures, and SRDQ than Generation X participants. Lower mindful eating scores were related to increased BMI among Generation Z, whereas lower label reading attitude scores were positively associated with WC and WHR. Furthermore, poor mindful eating and label reading attitudes and the combined effects of low mindful eating and label reading attitudes were linked to lower SRDQ.ConclusionPoor mindful eating and label reading attitudes in Generation Z may threaten long-term health sustainability and increase the risk of developing chronic diseases. Combining generation-specific public health strategies with interventions aimed at improving nutritional literacy and mindful eating habits from an early age could enhance individual and societal health outcomes.