Akcay, SumeyyeAkyol, Dudu KubraErkut, UmitCoskunsu, Dilber KaragozogluKunduracilar, ZuhalBajrami, ArsidaYavas, Arzu Dinc2026-02-102026-02-1020261545-96831552-684410.1177/15459683251412282https://doi.org/10.1177/15459683251412282https://hdl.handle.net/20.500.14627/1418Background: Respiratory dysfunction is common after stroke and may negatively affect functional recovery. Inspiratory muscle training (IMT) has been proposed to enhance diaphragmatic function and activity performance in this population. Objective: To investigate the effects of IMT on diaphragm function and activity performance in patients with subacute ischemic stroke. Methods: In this randomized controlled, single-blind trial, 26 patients with subacute ischemic stroke (>1 month post-onset) were randomly allocated to an intervention group (IG, n = 13) or control group (CG, n = 13). Both groups received standard neurorehabilitation, aerobic training, and the Active Cycle of Breathing Technique (ACBT). The IG additionally underwent IMT, 5 days per week for 6 weeks (30 sessions). Assessments included maximal inspiratory and expiratory pressures (MIP, MEP), diaphragmatic thickness (Ti, Te) and excursion via ultrasonography, 6-minute walk test (6MWT), and Canadian Occupational Performance Measure (COPM). Results: Twenty-two participants completed the study (IG = 11; CG = 11). Significant within-group improvements were observed in both groups for MIP, MEP, Ti, TF, excursion, 6MWT, and COPM scores (P < .05). Between-group analyses showed significantly greater improvements in the IG for Delta MIP (P < .001), Delta MEP (P = .003), affected-side Delta Ti (P = .007), Delta TF (P = .008), and Delta excursion (P = .005). No significant differences were found for 6MWT and COPM (P > .05). Conclusions: IMT effectively improves respiratory muscle strength, diaphragmatic thickness, and excursion in subacute ischemic stroke and may be a valuable addition to post-stroke rehabilitation programs.eninfo:eu-repo/semantics/closedAccessActivity PerformanceBreathing ExercisesDiaphragmIschemic StrokeUltrasonographyArticle